Patent application number | Description | Published |
20100014050 | APPARATUS AND METHOD OF DIAGNOSIS OF OPTICALLY IDENTIFIABLE OPHTHALMIC CONDITIONS - An apparatus that can measure images of at least a portion of an eye and record data sets indicative of a neurological condition. A method interrelates an image and a data set to provide an interpretive result. The apparatus and method thereby provide guidance as to the presence of a medical condition in a patient. The apparatus and method can be used in an iterative measurement process, in which the apparatus attempts to discern normal health from a state of health that is not normal health. If the interpretive result is consistent with normal health, the process terminates, information is recorded, and an optional report is given. If the interpretive result is not consistent with normal health, the apparatus and method attempts to distinguish which condition is consistent with the data and images used, and can iterate with additional measurements and information to attempt to provide a useful interpretive result. | 01-21-2010 |
20100238404 | DIAGNOSIS OF OPTICALLY IDENTIFIABLE OPHTHALMIC CONDITIONS - An apparatus for performing multiple procedures involving the eye. The apparatus includes an imager for imaging at least a portion of an eye of a patient, a data collection apparatus for collecting a data set corresponding to at least a portion of an eye of a patient, and a data analysis module. The imager is configured to provide image data. The data collection apparatus is configured to provide data indicative of a neurological disorder. The data analysis module interrelates the image data and the data indicative of a neurological disorder to provide an interpretive result. | 09-23-2010 |
20100238405 | DIAGNOSIS OF OPTICALLY IDENTIFIABLE OPHTHALMIC CONDITIONS - An apparatus for performing multiple procedures involving the eye. The apparatus includes a data collection apparatus and a data analysis module. The data collection apparatus for collecting a data set corresponding to at least a portion of an eye of a patient is configured to provide data indicative of at least two neurological disorders selected from the group consisting of glaucoma, macular degeneration, diabetic retinopathy, Parkinson's disease, Alzheimer's disease, dyslexia, multiple sclerosis, optic neuritis, LDS, head trauma, diabetes, and inappropriate responses to contrast sensitivity patterns. The data analysis module interrelates the data indicative of at least two neurological disorders to provide an interpretive result. | 09-23-2010 |
20130267784 | DIGITAL OTOSCOPE - An otoscope includes an instrument head, a tip element and an optical system. The instrument head has a distal insertion portion for insertion into an ear of a human or veterinary subject. The distal insertion portion has a distal opening. The tip element is releasably attached to the distal insertion portion. The tip element has a distal opening. The optical system is contained within the instrument head. The optical system includes a plurality of optical components. The optical system further comprises a viewing component for viewing of an image of a target of interest aligned along an optical axis disposed within said distal opening. The optical system is configured to provide a field of having a diameter equaling at least 7 mm at a distance of at least 15 mm from a distal opening of said attached tip element. The optical system is further configured to simultaneously provide a distance range of optimal focus having a range of at least 8 mm. The distance range of optimal focus includes a location at a working distance equal to about 30 mm. | 10-10-2013 |
20140176134 | APPARATUS FOR DIAGNOSIS OF OPTICALLY IDENTIFIABLE OPHTHALMIC CONDITIONS - An apparatus that can measure images of at least a portion of an eye and record data sets indicative of a neurological condition. A method interrelates an image and a data set to provide an interpretive result. The apparatus and method thereby provide guidance as to the presence of a medical condition in a patient. The apparatus and method can be used in an iterative measurement process, in which the apparatus attempts to discern normal health from a state of health that is not normal health. If the interpretive result is consistent with normal health, the process terminates, information is recorded, and an optional report is given. If the interpretive result is not consistent with normal health, the apparatus and method attempts to distinguish which condition is consistent with the data and images used, and can iterate with additional measurements and information to attempt to provide a useful interpretive result. | 06-26-2014 |
Patent application number | Description | Published |
20130219871 | Mounting Assembly for a Reductant Injector - A mounting assembly for an injector is located in a curved portion of an exhaust line having an exhaust flow from an upstream end to a downstream end. The mounting assembly includes an indent extending at least partially into the exhaust line curved portion and disposed in the exhaust flow. The downstream wall has an interior surface oriented to substantially face the exhaust line downstream end. A recess extends from the downstream wall in a direction away from the exhaust line downstream end, and a recess aperture is formed in the recess and configured to fluidly communicate with the injector. The recess reduces the amount of exhaust heat reaching the injector tip. | 08-29-2013 |
20140174696 | Injector Cooling Apparatus and Method - A system for cooling a reductant injector in an emissions module is provided. The system includes an emissions module, coupled to an engine exhaust duct, and a cooling system fluidly coupled to the emissions module. The emissions module includes a reductant system and a selective catalytic reduction (SCR) module. The reductant system includes a reductant injector having a cooling passage. The cooling system includes a reservoir tank, a supply pump fluidly coupled to the reservoir tank, and a siphon tank fluidly coupled to the supply pump and the reductant injector cooling passage. The siphon tank is disposed proximate to the reductant injector, and a gravitational elevation of a base of the siphon tank is greater than a gravitational elevation of the reductant injector. | 06-26-2014 |
20140331655 | Mounting Assembly for a Reductant Injector - A mounting assembly for an injector is located in a curved portion of an exhaust line having an exhaust flow from an upstream end to a downstream end. The mounting assembly includes an indent extending at least partially into the exhaust line curved portion and disposed in the exhaust flow. The downstream wall has an interior surface oriented to substantially face the exhaust line downstream end. A recess extends from the downstream wall in a direction away from the exhaust line downstream end, and a recess aperture is formed in the recess and configured to fluidly communicate with the injector. The recess reduces the amount of exhaust heat reaching the injector tip. | 11-13-2014 |
20140369899 | MULTI-COMPARTMENT PHAE SEPARATION TANK FOR MULTIPLE REDUCTANT INJECTORS - A cooling system in an aftertreatment unit for a multi-cylinder internal combustion engine is disclosed. The aftertreatment unit includes a selective catalyst reduction (SCR) module, an exhaust conduit portion, and a number of reductant injectors. Each reductant injector includes an injector coolant outlet. The cooling system supplies coolant to the reductant injectors by a coolant pump. A phase separation tank, positioned at a higher gravitational potential downstream of the reductant injectors, includes a number of compartments. Each compartment includes at least one inlet portion and at least one outlet portion. Each inlet portion is in fluid communication to the injector coolant outlet and each outlet portion is in fluid communication with the coolant reservoir. A coolant anti-siphon line portion facilitates fluid communication between the reductant injectors and the phase separation tank. Additionally, a coolant vent line facilitates fluid communication between the phase separation tank and the coolant reservoir. | 12-18-2014 |
Patent application number | Description | Published |
20090049563 | USING CYTOSINE DEAMINASES TO DIMINISH RETROELEMENT TRANSFER FROM PIGS TO HUMANS - Transgenic pigs that express one or more non-porcine cytosine deaminases are described as well as methods of making and using such pigs. | 02-19-2009 |
20100105140 | PLAICE DNA TRANSPOSON SYSTEM - This document describes the Passport transposon system and methods of making and using the same. | 04-29-2010 |
20100146655 | METHODS AND MATERIALS FOR PRODUCING TRANSGENIC ANIMALS - Transgenic artiodactyls are described as well as methods of making and using such artiodactyls. | 06-10-2010 |
20100251395 | USING CYTOSINE DEAMINASES TO DIMINISH RETROELEMENT TRANSFER FROM PIGS TO HUMANS - Transgenic pigs that express one or more non-porcine cytosine deaminases are described as well as methods of making and using such pigs. | 09-30-2010 |
20110059160 | METHODS AND COMPOSITIONS FOR TARGETED GENE MODIFICATION - Disclosed herein are methods and compositions for gene targeting utilizing fusion molecules comprising a recombinase domain and a sequence-specific DNA-binding domain. | 03-10-2011 |
20110197290 | METHODS AND MATERIALS FOR PRODUCING TRANSGENIC ARTIODACTYLS - Swine animal models comprising a genomic disruption of an endogenous gene chosen from the group consisting of a Low-Density Lipoprotein Receptor gene LDLR, Duchene's Muscular Dystrophy (DMD) gene, and hairless gene (HR). Methods of preparing transfected cells useful for making a transgenic animal comprising exposing a first group of cells to a transfection agent and reseeding the group with additional cells that have not been exposed to the agent. The transgenic animals are useful for medical and scientific animal models of human diseases and conditions, as well as sources for cells, tissues, and biomaterials. | 08-11-2011 |
20120220037 | METHODS AND MATERIALS FOR PRODUCING TRANSGENIC ARTIODACTYLS - Swine animal models comprising a genomic disruption of an endogenous gene chosen from the group consisting of a Low-Density Lipoprotein Receptor gene LDLR, Duchene's Muscular Dystrophy (DMD) gene, and hairless gene (HR). Methods of preparing transfected cells useful for making a transgenic animal comprising exposing a first group of cells to a transfection agent and reseeding the group with additional cells that have not been exposed to the agent. The transgenic animals are useful for medical and scientific animal models of human diseases and conditions, as well as sources for cells, tissues, and biomaterials. | 08-30-2012 |
20120222143 | GENETICALLY MODIFIED ANIMALS AND METHODS FOR MAKING THE SAME - Compositions and methods for use of TALENs to make genetically modified livestock are set forth. The methods may include reporters for selecting cells or embryos that have been modified by TALENs for use as progenitor cells to make founder animals. | 08-30-2012 |
20130090522 | METHOD AND MATERIALS FOR PRODUCING A GENETICALLY MODIFIED ANIMAL - Transgenic artiodactyls are described as well as methods of making and using such artiodactyls. | 04-11-2013 |
20130117870 | GENETICALLY MODIFIED ANIMALS AND METHODS FOR MAKING THE SAME - Compositions and methods for use of TALENs to make genetically modified livestock or other animals are set forth. Some of the embodiments of the invention provide for making an founder animal that is completely free of all unplanned genetic modifications. Some embodiments are directed to removing genetic faults in established breeds without making other alterations to the genome. Other embodiments are directed to particular tools or processes such as a TALENs with a preferred truncation. | 05-09-2013 |
20140041066 | PRODUCTION OF FMDV-RESISTANT LIVESTOCK BY ALLELE SUBSTITUTION - A genetically modified livestock animal comprising a genomic modification to an eIF4G gene. Cells, genes, and proteins encompassing a protease-resistant eIF4G protein or gene. | 02-06-2014 |
20140201857 | HORNLESS LIVESTOCK - Compositions and methods for making livestock with a polled allele are presented, including migrating a polled allele into a bovine species without changing other genes or chromosomal portions. | 07-17-2014 |
20140338007 | METHOD AND MATERIALS FOR PRODUCING A GENETICALLY MODIFIED ANIMAL - Transgenic artiodactyls are described as well as methods of making and using such artiodactyls. | 11-13-2014 |
20140351965 | SWINE GENETICALLY MODIFIED WITH SPECIFICITY FOR LDL-R KNOCKOUT - Compositions and methods for swine LDL-R gene knockouts. | 11-27-2014 |
20140359796 | GENETICALLY STERILE ANIMALS - A genetically modified livestock animal, and methods of making and using the same, the animal comprising a genetic modification to disrupt a target gene selectively involved in gametogenesis, wherein the disruption of the target gene prevents formation of functional gametes of the animal. Animals that create progeny with donor genetics, and methods of making and using the same. Cells, and methods of making and using the cells, with a genetic modification to disrupt a target gene selectively involved in gametogenesis. | 12-04-2014 |
20150067898 | EFFICIENT NON-MEIOTIC ALLELE INTROGRESSION - Methods, uses, and animals for introgression of alleles between animals, including SNPs. One embodiment involves introducing a targeted targeting endonuclease system and a HDR template into a cell with a mismatch in the binding of the targeting endonuclease and the targeted site. | 03-05-2015 |