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Eynon, US
Elizabeth Eynon, New Haven, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20110200982 | GENETICALLY MODIFIED MICE AND ENGRAFTMENT - A mouse with a humanization of the mIL-3 gene and the mGM-CSF gene, a knockout of a mRAG gene, and a knockout of a mIl2rg subunit gene; and optionally a humanization of the TPO gene is described. A RAG/Il2rg KO/hTPO knock-in mouse is described. A mouse engrafted with human hematopoietic stem cells (HSCs) that maintains a human immune cell (HIC) population derived from the HSCs and that is infectable by a human pathogen, e.g., | 08-18-2011 |
John S. Eynon, Bellingham, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090131478 | Growth Hormone Secretagogues - A family of peptides and peptidomimetic compounds useful as GHS analogs according to either formula (I) or (II) as depicted below: or a pharmaceutically acceptable salts thereof, wherein the variables are as defined in the specification. | 05-21-2009 |
| 20100016550 | Methods for Site-Specific Pegylation - The present invention relates to methods for the chemo-selective pegylation of the cysteine residue having unoxidized sulfhydryl side-chain and free α-amino group in proteins, peptides and other molecules. Similar methods are provided for the chemo-selective pegylation of the homocysteine, selenocysteine, penicillamine, and N-methyl-cysteine residues. | 01-21-2010 |
| 20100234564 | METHODS AND INTERMEDIATES FOR CHEMICAL SYNTHESIS OF POLYPEPTIDES AND PROTEINS - The present invention relates to methods and intermediates for chemical synthesis of polypeptides and proteins, and more particularly to methods and intermediates for chemically ligating a peptide fragment containing N-terminal N-methyl-cysteine (SEQ ID NO: 1) with another peptide fragment having C-terminal thioester to generate a β-(methylamino)-thioester intermediate that spontaneously rearranges to form an amide bond. Furthermore, the invention relates to methods of converting N-methyl-thiazolidine to N-methyl-cysteine (SEQ ID NO: 1) of polypeptides and proteins. The invention also relates to methods of synthesizing peptide-thioester from peptide-acid fluoride. | 09-16-2010 |
John Stuart Eynon, Bellingham, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100160604 | BOC AND FMOC SOLID PHASE PEPTIDE SYNTHESIS - A solid phase method for synthesizing a peptide containing three or more amino acid residues utilizing both Boc and Fmoc protected amino acids and a chloromethylated polystyrene resin. | 06-24-2010 |
Michael Eynon, Santa Cruz, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110099430 | METHOD AND SYSTEM TO MONITOR A DIVERSE HETEROGENEOUS APPLICATION ENVIRONMENT - A method to detect potential problems within a heterogeneous and diverse application environment. Operations data is received from a plurality of application servers within the application environment. The operations data pertains to operations performed at the plurality of application servers over a predetermined time interval. The operations data is aggregated. The aggregated data is compared to reference data, and a potential problem within the application environment is detected if the aggregated data deviates from the reference data in a predetermined manner. | 04-28-2011 |
Michael Eynon, Mountain View, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110185421 | SYSTEM AND METHOD FOR NETWORK SECURITY INCLUDING DETECTION OF MAN-IN-THE-BROWSER ATTACKS - A method is performed in a network security system implemented in a computer or electronic device that is coupled to secured online resources for detecting unauthorized accesses of those secured online resources. The method includes monitoring a user activity session. It is determined whether the user activity session is indicative of a hidden session by an attacker, where the determination includes comparing the user activity session to an average user activity session. | 07-28-2011 |
Mike Eynon, Mountain View, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20100235908 | System and Method for Detection of a Change in Behavior in the Use of a Website Through Vector Analysis - A system and method for identifying the change of user behavior on a website includes analyzing the actions of users on a website comprising a plurality of parameters or parameters that identify the actions performed on a website including parameters or fields related to previous actions by that user or other users of the website. The parameters or fields are represented in a vector format where each vector represents a different session of activity on the website, page of the website, user of the website, or other attribute of the use of a website. Analysis is performed to determine if new sessions are similar or dissimilar to previously known sessions. | 09-16-2010 |
| 20100235909 | System and Method for Detection of a Change in Behavior in the Use of a Website Through Vector Velocity Analysis - A system and software for identifying the change of user behavior on a website includes analyzing the actions of users on a website comprising a plurality of fields or input parameters that identify the actions performed on a website including fields related to previous actions by that user or other users of the website. The fields or input parameters are represented in a vector format where vectors represent different sessions of activity on the website, pages of the website, users of the website, or other attributes of the use of a website. Analysis is performed to determine if new sessions are similar or dissimilar to previously known sessions and if a session is converging or diverging from known sessions based on the velocity and direction of the velocity of the vectors in the vector space. | 09-16-2010 |