Inventors list

Assignees list

Classification tree browser

Top 100 Inventors

Top 100 Assignees


Exley, US

Jeremy Exley, Minneapolis, MN US

Patent application numberDescriptionPublished
20110005394MEDIA FOR REMOVAL OF ORGANIC COMPOUNDS - An air filter having a low pressure drop and adsorbent capabilities when placed in a fluid stream is disclosed. The air filter contains activated carbon incorporated into a filter media that can be shaped into a fluted configuration. The fluted shape is maintained during operation of the air filter through the use of flow restrictors along the length of the flute. The fluted material can be rolled or stacked.01-13-2011

John T. Exley, Toledo, OH US

Patent application numberDescriptionPublished
20100154435TURBINE ENGINE HAVING TWO OFF-AXIS SPOOLS WITH VALVING-ENABLED MODULATION BETWEEN HIGH AND LOW POWER MODES - A turbine engine particularly suited for VTOL aircraft is disclosed. According to various embodiments, the core of the turbine engine includes two spools—a low pressure (LP) spool and a high pressure (HP) spool—where the LP spool is independently mounted remote to the HP spool. The engine may be modulated for operation by a modulation diverter valve assembly and through the fuel flow to the engine. The power output from the engine can be modulated from high levels to low levels and vice versa through control of the air flow through the engine using the modulation diverter valve assembly. In lift mode operation both the LP and HP spools may be operational, while during the forward flight cruise mode of operation the HP spool is operational and the LP spool may or may not be operational depending upon the power required for the flight condition. For HP spool only operation, the LP spool may be shut down using the modulation diverter valve assembly and an inlet flow diverter valve assembly. The convertible configuration may be achieved by the diverter valving-enabled modulation of the engine airflow direction to produce a characteristic for one embodiment having shaft power output for the vertical lift mode to propulsive thrust output for forward flight mode.06-24-2010

Mark A. Exley, Chestnut Hill, MA US

Patent application numberDescriptionPublished
20100068222Hapten-carrier conjugates for use in drug abuse therapy and methods for preparation of same - Hapten-carrier conjugates capable of eliciting anti-hapten antibodies in vivo by administering, in a therapeutic composition, are disclosed. Methods of preparing said conjugates and therapeutic compositions are also disclosed. Where the hapten is a drug of abuse, a therapeutic composition containing the hapten-carrier conjugate is particularly useful in the treatment of drug addiction, more particularly, cocaine addiction. Passive immunization using antibodies raised against conjugates of the instant invention is also disclosed. The therapeutic composition is suitable for co-therapy with other conventional drugs.03-18-2010
20100105672Hapten-carrier conjugates for use in drug-abuse therapy and methods for preparation of same - Hapten-carrier conjugates capable of eliciting anti-hapten antibodies in vivo by administering, in a therapeutic composition, are disclosed. Methods of preparing said conjugates and therapeutic compositions are also disclosed. Where the hapten is a drug of abuse, a therapeutic composition containing the hapten-carrier conjugate is particularly useful in the treatment of drug addiction, more particularly, cocaine addiction. Passive immunization using antibodies raised against conjugates of the instant invention is also disclosed. The therapeutic composition is suitable for co-therapy with other conventional drugs.04-29-2010
20100209449HAPTEN-CARRIER CONJUGATES FOR USE IN DRUG-ABUSE THERAPY AND METHODS FOR PREPARATION OF SAME - Hapten-carrier conjugates capable of eliciting anti-hapten antibodies in vivo by administering, in a therapeutic composition, are disclosed. Methods of preparing said conjugates and therapeutic compositions are also disclosed. Where the hapten is a drug of abuse, a therapeutic composition containing the hapten-carrier conjugate is particularly useful in the treatment of drug addiction, more particularly, cocaine addiction. Passive immunization using antibodies raised against conjugates of the instant invention is also disclosed. The therapeutic composition is suitable for co-therapy with other conventional drugs.08-19-2010

Patent applications by Mark A. Exley, Chestnut Hill, MA US

Mark A. Exley, Boston, MA US

Patent application numberDescriptionPublished
20090068210IMMUNOTHERAPY FOR HEMATOLOGICAL MALIGNANCIES - Methods and compositions for treating, preventing and/or managing various hematological malignancies are disclosed. Specific methods and compositions relate to use of tumor cells engineered to express antigen presenting molecules which present antigens recognized by iNKT cells and eliciting antitumor immune response from iNKT cells using such tumor cells, optionally in combination with an immunomodulatory compound.03-12-2009

Ray W. Exley, Beverly Hills, CA US

Patent application numberDescriptionPublished
201101054342-AMINO PURINE DERIVATIVES AND THEIR USE AS ANTI-HERPETIC AGENTS - Anti-herpetic material such as 2-amino purine derivatives to prevent or treat autoimmune disease or a disease originating from an abnormal functioning of the sympathetic chain in a human subject. The disease is often of a tissue or organ associated with decreased blood flow to the tissue or organ (correlated with hypertonicity of the vessels feeding the tissue or organ). The treatment reduces inflammation, scarring, destruction, and pain in the tissue or organ affected and returns the tissue or organ to nearly normal functioning, while showing none of the side effects of previous treatments. Prolonged use of the anti-herpetic compounds reduces prodrome, vesicle formation and viral shedding. The anti-herpetic compounds may be administered alone or in combination with a compound that reduces the rate of renal excretion of the anti-herpetic compound. The anti-herpetic compounds are particularly useful when administered at a level equivalent in activity to 250 mg/kg famciclovir per day.05-05-2011
20110112117TREATMENT OF HERPES VIRUS RELATED DISEASES - Anti-herpetic material such as 2-aminopurine derivatives, e.g., the aminocyclopropylcarboxylate derivatives of acyclovir, penciclovir, and ganciclovir, are described to prevent or treat autoimmune disease or a disease originating from an abnormal functioning of the sympathetic chain in a human subject. Prolonged use of the anti-herpetic compounds reduces prodrome, vesicle formation and viral shedding. The anti-herpetic compounds may be administered alone or in combination with a compound that reduces the rate of renal excretion of the anti-herpetic compound. The anti-herpetic compounds are particularly useful when administered at a level equivalent in activity to at—least about 150 mg/kg famciclovir per day.05-12-2011

Ross Exley, Clifton, NJ US

Patent application numberDescriptionPublished
20110278869TWEEZERS - A hand tool includes a main body, a pair of arms connected to the main body, first tips connected to the arms and configured to grasp an object, and second tips connected to the arms and configured to grasp an object. The first tips are connected to the second tips. Another aspect of the invention is directed to a hand tool including a main body, a pair of arms connected to the main body, and a scoop portion at one end of the main body.11-17-2011

Ross James Exley, Hoboken, NJ US

Patent application numberDescriptionPublished
20100116115Flat paper punch - A punch for punching a sheet of material the punch having a body formed with a fissure for receiving the sheet of material, a pivot shaft defining a pivot point and a lever retaining means secured to said body. A lever pivotably mounted about the pivot point of said pivot shaft, is provided, the lever having an open position when one end of the lever is elevated to a height above the pivot point, and the lever having a closed position in which the lever is positioned parallel to the fissure. A block is provided which is positionable between the lever and the body. The body is provided with longitudinal support ridges and the lever is provided with side ridges, with the pivot point positioned in substantially the same plane as the longitudinal support ridge so that when the punch is closed, the side ridges of the lever pass outside of the support ridges of the body in a nesting relationship, allowing the punch to form a flat profile when closed.05-13-2010