Evaldas
Evaldas Ciplys, Vilnius LT
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20150191713 | Generation of Native Recombinant Secreted Human Endoplasmic Reticulum Chaperones by Using Their Native Signal Sequences in Yeast Expression Systems - A method using yeast as a host for production of human ER chaperone proteins, using endogenous signal peptides of intracellular human proteins that are recognized and correctly processed in the yeast cells to subsequently lead to the secretion of the human proteins. The resultant proteins possessed native amino acid sequence and were biologically active. Moreover, secretion allowed simple one-step purification of native recombinant human proteins with high yields. | 07-09-2015 |
Evaldas Katilius, Superior, AZ US
Patent application number | Description | Published |
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20100009868 | Self-Assembled Combinatorial Encoding Nanoarrays for Multiplexed Biosensing - The present invention provides combinatorial encoding nucleic acid tiling arrays and methods for their use and synthesis. | 01-14-2010 |
20120231467 | Aptamers for C. Difficile Diagnostics - The present disclosure relates generally to the field of nucleic acids and, more particularly, to aptamers capable of binding to toxins produced by | 09-13-2012 |
20150031585 | Multiaptamer Target Detection - Described herein are compositions comprising a first aptamer, second aptamer and a target that are capable of forming a ternary complex, and wherein the first aptamer and the second aptamer comprise C-5 pyrimidine modification schemes that are different, and methods of making and using such compositions. | 01-29-2015 |
20150125867 | Aptamers for Clostridium Difficile Diagnostics - The present disclosure relates generally to the field of nucleic acids and, more particularly, to aptamers capable of binding to toxins produced by | 05-07-2015 |
20150141259 | Aptamer-Based Multiplexed Assays - The present disclosure describes methods, devices, reagents, and kits for the detection of one or more target molecules that may be present in a test sample. The described methods, devices, kits, and reagents facilitate the detection and quantification of a non-nucleic acid target (e.g., a protein target) in a test sample by detecting and quantifying a nucleic acid (i.e., an aptamer) where the aptamer-aptamer interactions are significantly reduced or eliminated while maintaining the aptamer-target interaction. | 05-21-2015 |
Evaldas Katilius, Phoenix, AZ US
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20090054250 | Methods to create fluorescent biosensors using aptamers with fluorescent base analogs - The present invention provides improved methods for generating fluorescent aptamer polynucleotides, novel polynucleotides, and methods for use thereof. | 02-26-2009 |
Evaldas Malinauskas, Berlin, CT US
Patent application number | Description | Published |
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20080202180 | SHAPED TOP PIN FOR BUMP RESISTANT CYLINDER - The present invention provides a pin and tumbler cylinder lock and a retrofitted cylinder lock which minimizes unauthorized openings of the lock by bumping. The cylinder lock utilizes specially designed driver pins which are correlated in size to the largest possible stack height of the tumbler pins with a bump key inserted in the plug portion of the lock and the shear line height of the lock. All the driver pins are about the same height and preferably symmetrical with a lip on each end. The invention also provides a method for retrofitting existing locks by removing at least one of the driver pins and replacing the removed driver pin or pins with the driver pins of the invention. | 08-28-2008 |
Evaldas Pabreza, Vilnius LT
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20160123888 | SURFACE ENHANCED RAMAN SCATTERING (SERS) SENSOR AND A METHOD FOR PRODUCTION THEREOF - A plasmonic sensor, having at least a substrate, a laser processed active surface area on the said substrate, and a metal coating on the activate surface, where the laser processed surface is fabricated by means of short laser pulses in such a way that in a shallow layer of the surface material, the viscosity is reduced and under the influence of the same pulse, which was used to reduce the viscosity, or a successive incident one or more pulses a self-organized, stochastic nanostructure is formed, which has features smaller than 1 μm. In some implementations, the substrate material is amorphous, such as soda-lime glass or similar. Also disclosed is a slide and/or a slip cover, which are used in microscopy, for forming the active sensor area on top surface of it. | 05-05-2016 |