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Esben Peter Friis

Esben Peter Friis, Herlev DK

Patent application numberDescriptionPublished
20090170157Asparaginases - The invention relates to new asparaginases having improved properties, preferably improved thermotolerance, such as improved activity at high temperatures and/or improved thermostability. The invention also relates to DNA sequences encoding such improved asparaginases, their production in a recombinant host cell, as well as methods of using the asparaginases, in particular for reduction of acrylamide in foods. The invention furthermore relates to methods of generating and preparing asparaginase variants having improved properties.07-02-2009
20090312221DETERGENT COMPOSITION COMPRISING A VARIANT OF A FAMILY 44 XYLOGLUCANASE - The present invention relates to detergent compositions comprising a variant of a parent xyloglucanase.12-17-2009
20100055726ASPARAGINASES - The invention relates to new asparaginases having improved properties, preferably improved thermotolerance, such as improved activity at high temperatures and/or improved thermostability. The invention also relates to DNA sequences encoding such improved asparaginases, their production in a recombinant host cell, as well as methods of using the asparaginases, in particular for reduction of acrylamide in foods. The invention furthermore relates to methods of generating and preparing asparaginase variants having improved properties.03-04-2010
20100083392HAFNIA PHYTASE VARIANTS - The present invention relates to phytases having at least 76% identity to a phytase derived from 04-01-2010
20100221385ASPARAGINASES - The invention relates to new asparaginases having improved properties, preferably improved thermotolerance, such as improved activity at high temperatures and/or improved thermostability. The invention also relates to DNA sequences encoding such improved asparaginases, their production in a recombinant host cell, as well as methods of using the asparaginases, in particular for reduction of acrylamide in foods. The invention furthermore relates to methods of generating and preparing asparaginase variants having improved properties.09-02-2010
20110039752Stabilized Liquid Enzyme Compositions - Peptide aldehydes or ketone derivatives are particularly efficient for stabilizing subtilisin-type proteases in aqueous compositions such as liquid detergents, including peptide compounds with OH-substituted phenylalanine aldehyde as the C-terminal residue.02-17-2011
20110092409VARIANTS OF A FAMILY 44 XYLOGLUCANASE - The present invention relates to variants of a parent xyloglucanase. The present invention also relates to polynucleotides encoding the variant xyloglucanases and to nucleic acid constructs, vectors, and host cells comprising the polynucleotide.04-21-2011
20110124576Transferrin Variants and Conjugates - Based on the three-dimensional structure of transferrin, the inventors have designed variant polypeptides (muteins) which have one or more Cysteine residues with a free thiol group (hereinafter referred to as thiotransferrin). The variant polypeptide may be conjugated through the sulphur atom of the Cysteine residue to a bioactive compound.05-26-2011

Patent applications by Esben Peter Friis, Herlev DK

Esben Peter Friis, Valby DK

Patent application numberDescriptionPublished
20080280328Glucoamylase Variants - The present invention relates to glucoamylase variants with improved properties and methods of utilizing the glucoamylase variants.11-13-2008
20110045572PROTEIN VARIANTS HAVING MODIFIED IMMUNOGENICITY - The present invention relates to a method of selecting a protein variant having modified immunogenicity as compared to the parent protein comprising the steps obtaining antibody binding peptide sequences, using the sequences to localise epitope sequences on the 3-dimensional structure of parent protein, defining an epitope area including amino acids situated within 5 Å from the epitope amino acids constituting the epitope sequence, changing one or more of the amino acids defining the epitope area of the parent protein by genetical engineering mutations of a DNA sequence encoding the parent protein, introducing the mutated DNA sequence into a suitable host, culturing said host and expressing the protein variant, and evaluating the immunogenicity of the protein variant using the parent protein as reference. The invention further relates to the protein variant and use thereof, as well as to a method for producing said protein variant.02-24-2011

Patent applications by Esben Peter Friis, Valby DK