Patent application number | Description | Published |
20080262016 | ISOQUINOLINE DERIVATIVES AND METHODS OF USE THEREOF - The invention provides novel classes of Isoquinoline Derivatives. Pharmaceutical compositions and methods of making and using the compounds, are also described. | 10-23-2008 |
20130317031 | Nuclear Transport Modulators And Uses Thereof - The present invention relates to compounds of formula I: | 11-28-2013 |
20140155381 | COMPOUNDS AND METHODS - The present invention relates to novel retinoid-related orphan receptor gamma (RORγ) modulators and their use in the treatment of diseases mediated by RORγ. | 06-05-2014 |
20140155419 | COMPOUNDS AND METHODS - The present invention relates to novel retinoid-related orphan receptor gamma (RORγ) modulators and their use in the treatment of diseases mediated by RORγ. | 06-05-2014 |
20140256740 | COMPOUNDS AND METHODS - The present invention relates to novel retinoid-related orphan receptor gamma (RORγ) modulators and their use in the treatment of diseases mediated by RORγ. | 09-11-2014 |
20140315881 | COMPOUNDS AND METHODS - The present invention relates to novel retinoid-related orphan receptor gamma (RORγ) modulators and their use in the treatment of diseases mediated by RORγ. | 10-23-2014 |
20150111893 | Nuclear Transport Modulators and Uses Thereof - The present invention relates to compounds of formula I: and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising the compounds of formula I, and methods of using said compounds, salts and compositions in the treatment of various disorders associated with CRM1 activity. | 04-23-2015 |
Patent application number | Description | Published |
20100183384 | Machine tool and cutting ring for a machine tool - The invention relates to a machine tool for use in tool machines, comprising a cutting element which is preferably configured as a cutting ring and at least two insert seats that are provided in the cutting element at distance to each other in the circumferential direction. The insert seats are fitted with at least one group of at least two identical insert tips that are detachably arranged therein and that have one working edge each, the effective working edges of the insert tips of one group being cut to the same nominal size. The insert tips are configured as indexable inserts, every single indexable insert of a group being associated with a defined insert seat in all possible positions of adjustment, and the indexable inserts of a group having at least two working edges each, one of these edges being always in the effective and at least one other edge being in the ineffective position, depending on the position of the indexable inserts in the associated insert seats. The indexable inserts of a group assume identical positions of adjustment in which defined working edges of every indexable insert of a group have the same orientation in the associated insert seat, the working edges of the indexable inserts of a group being cut to a nominal size in all common positions of adjustment. | 07-22-2010 |
20110116877 | ROTATING CUTTING TOOL WITH SUPPORT ELEMENT - The invention relates to a rotating cutting tool, in particular a boring tool for use in machine tools. The cutting tool comprises at least one cutting insert, designed as an indexable insert, that has an active main blade located near a corner of the insert, the outer end of said blade defining a circular flight path radius (R) as the blade rotates, said blade penetrating into a work piece at a pre-determined cutting depth (t) near a pre-formed round hole. Also provided is a secondary blade that is disposed opposite to an advancing direction and that aligns with the outermost end of the main blade, the entire length of said blade having a smaller radius than the circular flight path radius (R) of the main blade, wherein a secondary blade free surface aligns with the secondary blade opposite to the direction of rotation. A unique characteristic of the invention is that the secondary blade free surface comprises a support part disposed at a distance from the secondary blade, the peripheral radius of said part being larger than the circular flight path radius R of the active main blade by an overshoot amount (Y). | 05-19-2011 |
20110123281 | MACHINE TOOL WITH ADJUSTABLE CUTTING PLATE - The invention relates to a machine tool with an adjustable cutting plate. The rotating machine tool substantially comprises a base member with a rotating axis, at least one pocket formed in the base member and at least one blade support holding a cutting plate. Two side surfaces of the blade support sit against a side support surface, respectively, said blade support side surfaces making an angle between them, and the base of the blade support sits against a base support surface of the pocket, the blade support being clamped in the pocket removably by way of a clamp element. The cutting plate protrudes over the blade support with an effective blade and over the base member outward. In order to enable a fine-adjustment of tangential cutting plates in the base member, it is proposed that the base support surface form a wedge surface that includes an acute angle together with a shift axis, said wedge surface disposed at an adjusting member that can shift relative to the base member along said shift axis, the base of said blade support, in the shape of a complementary wedge, abutting against said wedge surface. Also, the two side support surfaces form guide surfaces for the blade support that are directed substantially perpendicular relative to the shift axis of the adjusting member when said blade support makes a shifting motion by way of a shifting of the adjusting member. | 05-26-2011 |
20110318118 | MACHINE TOOL HAVING ADJUSTABLE PLATE ELEMENT - The main body ( | 12-29-2011 |
20140348606 | REAMING TOOL AND METHOD FOR THE PRODUCTION THEREOF - The invention relates to a reaming tool, comprising a rotationally drivable main body ( | 11-27-2014 |
Patent application number | Description | Published |
20090304907 | COATING SYSTEM AND METHOD FOR COATING A SUBSTRATE - A coating system comprises a lock-in chamber and a lock-out chamber. Furthermore, the coating system comprises a first transfer chamber connected with the lock-in chamber and the lock-out chamber. In the transfer chamber a first rotatable transfer module is arranged. The substrate holders may be rotated around a central axis such that substrate holders may be positioned in alignment with the lock-in chamber and the lock-out chamber, respectively. The coating station further includes a first process chamber and a second process chamber. Furthermore, the coating system includes a second transfer chamber having a second rotatable transfer module including a third substrate holder and a fourth substrate holder. The second transfer chamber is connected with the first process chamber and the second process chamber as well as a third process chamber and a fourth process chamber. The third process chamber and the fourth process chamber are arranged parallel, i.e., like a cluster arrangement, at the second transfer chamber. The invention provides for a possibility to increase the availability of the system by a sandwich arrangement of two parallel coating chambers and arranged on a forward path and a return path, respectively, between two transfer chambers which are configured to transfer the substrate from the forward path to the return path and vice versa. | 12-10-2009 |
20090324368 | PROCESSING SYSTEM AND METHOD OF OPERATING A PROCESSING SYSTEM - A coating system comprises a swing station including a swing module and an arrangement of chambers. The arrangement of chambers comprises a lock chamber and a first coating chamber. The lock chamber is configured as a combined lock-in/lock-out chamber. The arrangement of chambers has a first substantially linear transport path indicated by dashed lines, and a second substantially linear transport path indicated by dashed lines. The arrangement of the paths establishes a dual track. The system includes a transport system for moving a substrate through the arrangement of chambers, along the first transport path and/or along the second transport path as indicated by arrows. One or particularly both chambers comprise transfer means for transferring the substrate/carrier from the first path to the second path by a lateral movement and/or from the second path to the first path. | 12-31-2009 |
20110299961 | PROCESSING SYSTEM AND METHOD OF OPERATING A PROCESSING SYSTEM - A coating system | 12-08-2011 |
20120213938 | SYSTEM FOR UTILIZATION IMPROVEMENT OF PROCESS CHAMBERS AND METHOD OF OPERATING THEREOF - A substrate processing system for processing an essentially vertically oriented substrate is described. The system includes a first processing chamber having a first processing region and being adapted to deposit a first layer comprising a first material, a second processing chamber having a second processing region and being adapted to deposit a second layer over the first layer, the second layer comprising a second material, a third processing chamber having a third processing region and being adapted to deposit a layer comprising the second material, a transfer chamber providing essentially linear transport paths with the first, the second, and the third chambers, respectively, and a further chamber comprising a first and a second transportation track, wherein at least one of the first and second transportation tracks forms an essentially linear transportation path with the first processing chamber, wherein the first chamber is adapted to receive the substrate from the transfer chamber, and to deposit a further layer comprising the first material. | 08-23-2012 |
20140044880 | COATING APPARATUS AND METHOD - A substrate processing system for processing an essentially vertically oriented substrate is described. The system includes a first processing chamber having a first processing region to deposit a first layer comprising a first material, a second processing chamber having a second processing region to deposit a second layer over the first layer, the second layer comprising a second material, a third processing chamber having a third processing region to deposit a layer comprising the second material, a transfer chamber providing essentially linear transport paths with the first, second, and third chambers, respectively, and a chamber comprising a first and a second transportation track, wherein at least one of the first and second transportation tracks forms an essentially linear transportation path with the first processing chamber, wherein the first chamber is adapted to receive the substrate from the transfer chamber, and to deposit a further layer comprising the first material. | 02-13-2014 |
20150303041 | METHOD AND SYSTEM FOR MAINTAINING AN EDGE EXCLUSION SHIELD - A method for extracting a shielding element from a processing chamber of a substrate processing system or inserting the shielding element into the processing chamber is provided. The substrate processing system includes the processing chamber, a first shielding element for excluding application of material onto parts of a substrate, and a substrate transportation system for transporting substrates or substrate carriers into and out of the processing chamber. The method includes transporting the first shielding element by the substrate transportation system. | 10-22-2015 |