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Erickson, MD

Donald Charles Erickson, Annapolis, MD US

Patent application numberDescriptionPublished
20090031999Charge air chiller - A system for chilling the pressurized charge air to a reciprocating engine is disclosed wherein the chilling is provided by a thermally activated refrigeration cycle powered by waste heat from the engine system. This reduces the required compression power, and also retards knock, making higher compression ratios possible. The chilling system is designed to minimize the amount of chilling required, and also to enable use of compression heat to power the chiller. The disclosed improvement also accommodates exhaust gas recirculation, plus providing activation heat from the exhaust gas, plus Miller cycle timing of the intake valves. Referring to FIG. 02-05-2009
20090049836Thermally powered turbine inlet air chiller heater - An improvement to the air compressor of a combustion turbine system is disclosed, which makes the air compression more energy efficient plus have higher capacity on warm days. The same equipment with minimal modification is used to prevent inlet air icing conditions on cold days. Referring to FIG. 02-26-2009
20100096115Multiple concentric cylindrical co-coiled heat exchanger - A compact shell and coil heat exchanger is disclosed that accommodates widely differing volumetric flowrates between the two fluids undergoing heat exchange. Multiple co-coiled helical coils of tubing are concentrically arranged, and coil spacers are provided which maintain the tubes in overall staggered alignment, as illustrated in FIG. 04-22-2010
20100175395Hybrid spray absorber - A hybrid absorber is disclosed for a closed absorption cycle apparatus. The hybrid absorber is comprised of a non-adiabatic section plus an adiabatic spray section in that order, with absorbent solution and vapor supplied sequentially to them. The spray section preferably also includes a non-adiabatic spray cooler. Coolant is supplied to the non-adiabatic absorber and the cooler either in parallel or in series, countercurrently to the absorbent.07-15-2010
20100229594Chilling economizer - Chilling is produced from heat that is normally wasted in the economizer section of a steam boiler. A thermally-activated ammonia-water absorption chiller is powered by a heat recovery unit. The heat recovery unit supplies boiler exhaust heat to desorb the working fluid of the chiller. That can be directly, such that the heat recovery unit is a heat recovery vapor generator that can be colocated with an economizer, in parallel or series. The exhaust heat can alternatively be supplied to the AARC indirectly, via a heat transfer loop and a separate generator. The desorbed ammonia vapor is rectified, condensed, and then used to produce the chilling. The heat released in the chiller when low pressure ammonia vapor is re-absorbed is used to preheat the boiler feedwater.09-16-2010
20100275629Liquid desiccant chiller - A thermally activated air conditioning system is disclosed that both dries and chills the air being conditioned. Drying is by a liquid desiccant subsystem, and chilling is by an absorption chilling subsystem. A very high COP (1.25) is obtainable owing to the use of reject heat from the absorption subsystem to power the desiccant subsystem. The overall system (or cycle) is powered by relatively low temperature input heat (e.g. 245° F.). That heat can be obtained from flat plate or evacuated tube solar collectors, or other sources. The low driving temperature is made possible by the disclosed integration between the two subcycles.11-04-2010
20100293973Combined cycle exhaust powered turbine inlet air chilling - An ammonia absorption refrigeration apparatus is disclosed that has advantageous features to enable it to be integrated with a power plant comprised of a combustion turbine plus a heat recovery steam generator (e.g. a combined cycle plant), in a manner so as to enhance the performance of the power plant. Exhaust heat from the power plant powers the AAR, and refrigeration from the AAR chills the inlet air to the combustion turbine. Thus the power plant output is markedly increased on hot days at high efficiency, with little or no parasitic penalty.11-25-2010

John W. Erickson, Potomac, MD US

Patent application numberDescriptionPublished
20100009935RESISTANCE-REPELLENT RETROVIRAL PROTEASE INHIBITORS - Resistance-repellent and multidrug resistant retroviral protease inhibitors are provided. Pharmaceutical composition comprising such compounds, and methods of using such compounds to treat HIV infections in mammals, are also provided.01-14-2010
20110098237METHODS FOR INHIBITING DRUG DEGRADATION - Methods of inhibiting cytochrome P450 enzymes are provided that can be used for improving the treatment of diseases by preventing degradation of drugs or other molecules by cytochrome P450. Pharmaceutical compositions are provided that can act as boosters to improve the pharmacokinetics, enhance the bioavailability, and enhance the therapeutic effect of drugs that undergo in vivo degradation by cytochrome P450 enzymes.04-28-2011
20110112137HIV PROTEASE INHIBITOR AND CYTOCHROME P450 INHIBITOR COMBINATIONS - Compositions and methods of treating viral infections are provided. More particularly, compositions including a combination of protease inhibitors and cytochrome p450 enzyme inhibitors are provided. Methods of using the compositions for treatment of diseases or disorders caused by a virus such as HIV infections are also provided.05-12-2011

Patent applications by John W. Erickson, Potomac, MD US

John W. Erickson, Frederick, MD US

Patent application numberDescriptionPublished
20110166061LONG LASTING FUSION PEPTIDE INHIBITORS FOR HIV INFECTION - The present invention is concerned with This invention relates to C34 peptide derivatives that are inhibitors of viral infection and/or exhibit antifusogenic properties. In particular, this invention relates to C34 derivatives having inhibiting activity against human immunodeficiency virus (HIV), respiratory syncytial virus (RSV), human parainfluenza virus (HPV), measles virus (MeV), and simian immunodeficiency virus (SIV) with long duration of action for the treatment of the respective viral infections.07-07-2011