Patent application number | Description | Published |
20110104179 | PROTEASE INHIBITORY PEPTIDES - The present invention relates to compounds, peptides, peptidomimetics and pharmaceutical compositions that inhibit protease activity, and the use of these compounds, peptides, peptidomimetics and pharmaceutical compositions comprising them to treat or prevent a condition. In particular the condition may be periodontal disease. The compounds, peptides and peptidomimetics may be obtained from various caseins, for example α-casein, β-casein and κ-casein. The protease activity which the compounds, peptides, peptidomimetics and pharmaceutical compositions of the invention inhibit includes that of the gingipains. | 05-05-2011 |
20120283174 | ANTIBIOFILM GLYCOPEPTIDES - The present invention relates to peptides and compositions that have antibiofilm properties. In particular, the peptides and compositions of the invention can be used for the treatment or prevention of various conditions including dental caries, gingivitis, periodontitis, oral mucositis, dry mouth and xerostomia. | 11-08-2012 |
20130028847 | BIOFILM TREATMENT - The invention provides a method of preventing, inhibiting or reducing a | 01-31-2013 |
20130129768 | TREATMENT OR PREVENTION OF INFECTION - The invention relates to a method of reducing the incidence or severity of a disease or condition in a subject, said disease or condition being one associated with the presence of a microbial pathogen in an oral tissue of a subject, and including the use of a composition forming an anti-microbial and an immunogen against a microbial pathogen. | 05-23-2013 |
20130202641 | IMMUNOLOGY TREATMENT FOR BIOFILMS - The invention provides a composition for use in raising an immune response to | 08-08-2013 |
20140056824 | IONIC COMPLEXES - The present invention provides a phosphopeptide or phosphoprotein (PP) stabilised amorphous calcium phosphate or amorphous calcium fluoride phosphate complex having a calcium ion greater than about 30 moles of calcium per mole of PP. | 02-27-2014 |
20140147512 | DENTAL MINERALIZATION - A method is provided for mineralizing a dental surface or subsurface including contacting the dental surface with a protein disrupting agent and stabilized amorphous calcium phosphate (ACP) or amorphous calcium fluoride phosphate (ACFP). | 05-29-2014 |
20140288007 | GINGIPAIN INHIBITORY PROPEPTIDES - The disclosure relates to compounds, peptides or peptidomimetics that inhibit, reduce or prevent protease activity and the use of these compounds, peptides or peptidomimetics to treat or prevent a condition. In particular the condition may be periodontal disease. The protease activity may be activity of a gingipain. The compounds, peptides or peptidomimetics of the invention may also be used in assays for the identification of protease inhibitors. | 09-25-2014 |