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Erbacher
Jonathan George Erbacher, Twinsburg, OH US
| Patent application number | Description | Published |
|---|---|---|
| 20090302050 | BIASED PAPER DISPENSING DEVICE - Disclosed is a biased paper dispensing device for dispensing paper. The dispensing device has a housing with an elongated body for containing paper. The housing has a lift system which may include a tray for holding the paper, a pulley system having pulleys, and elastic tubing. The tray holds the paper horizontally in the housing, and is moved vertically within the housing to dispense the paper. The lift system is used to lift or lower the paper and to bias the paper within the housing toward the lid or opening. A paper guide device for guiding paper into alignment with the opening may be provided. The opening may include at least one lateral opening portion permitting paper exposed in the opening to be withdrawn laterally therefrom. Flanges for holding the paper within the opening, and for allowing easy insertion of paper into the housing, are also provided. | 12-10-2009 |
Patrick Erbacher, Benfeld FR
| Patent application number | Description | Published |
|---|---|---|
| 20100048672 | COMPOSITIONS FOR TRANSFECTION OF OLIGONUCLEOTIDES ACTIVE FOR GENE SILENCING AND THEIR BIOLOGICAL AND THERAPEUTICAL APPLICATIONS - The invention relates to compositions of transfection comprising an oligonucleotide and an amphiphilic cationic molecule of formula (I) wherein, —X is N—R | 02-25-2010 |
| 20100297756 | MEANS FOR DELIVERY OF NUCLEIC ACIDS ACTIVE FOR GENE SILENCING USING SYNTHETIC POLYMERS - The invention relates to a composition useful as transfection agent, comprising polyamines modified by aromatic amino acids and small double-strand or single-strand RNA active for RNA interference. | 11-25-2010 |
| 20100311056 | METHOD FOR HYBRIDIZING NUCLEIC ACIDS - The invention relates to a method for manipulating, isolating, detecting or amplifying a target nucleic acid in a sample by hybridization with an oligonucleotide-oligocation conjugate, comprising allowing said nucleic acid to react with an oligonucleotide-oligocation conjugate comprising at least A1 and Bj linked together directly or via a linker, wherein. A, is an i-mer oligonucleotides, with i=3 to 50, where Ai is an oligomer with naturally or non naturally occurring nucleobases and/or pentafuranosyl groups and/or native phosphodiester bonds, optionally comprising a marker group. Bj is a j-mer organic oligocation moiety, with j=1 to 50, where B is —HPO | 12-09-2010 |
| 20110091935 | PRODUCTION OF RECOMBINANT PROTEINS IN SYNTHETIC MEDIUM - The invention relates to a method for the production of recombinant proteins by eucaryotic cells in synthetic culture media, wherein said eucaryotic cells are transfected with a composition comprising a synthetic transfection reagent based on a polyhydroxylated polyalkyleneimine. | 04-21-2011 |
Patrick Erbacher, Illkirch Graffenstaden FR
| Patent application number | Description | Published |
|---|---|---|
| 20100197888 | Method for Manufacturing Linear Polyethylenimine (PEI) for Transfection Purpose and Linear PEI Obtained with Such Method - The invention concerns a method of synthesising and preparing linear polyethylenimine (PEI) for use as a transfection vector, and the product obtained with such a method. It comprises drying a monomer 2-ethyl-2-oxazoline and polymerising said monomer for obtaining poly (2-ethyl-2-oxazoline) (PEOX) by: using acetonitrile as solvent, adding a dried initiator of the reaction of polymerisation, and mixing them altogether, purifying said obtained PEOX by evaporation, while performing at least three times successive washing/precipitation steps with methanol and diethyl ether and corresponding filtrations, in order to obtain (i), by performing 1H-NMR tests, correct identification of said PEOX polymer, confirmation of absence of monomer to a level <1.0% and confirmation of absence of solvent to a level <5.0% and (ii), by performing Gel Permeation Chromatography, a mean of molecular weight (Mw)>23,000 Da and polydispersity (Mw/Mn) of said PEOX<1.5, hydrolysing said PEOX. | 08-05-2010 |