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Epstein, NY
Benjamin Ross Epstein, Forest Hills, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20110302066 | Method and system for automated tax appeal - A system and method enables users to prepare property and other types of tax appeal forms by an automated template while performing back-end database look-ups and analyses to determine the extent of the appeal. The template can be readily adjusted or added by system administrators to accommodate changes in the tax procedures or newly added jurisdictions, respectively. | 12-08-2011 |
Brian D. Epstein, Delmar, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20080270237 | SYSTEM AND METHOD FOR MODIFYING INTERNET TRAFFIC AND CONTROLLING SEARCH RESPONSES - A system, method and program product for modifying data packets being communicated between a client and a Web application to enhance the Web experience of a user. A system is disclosed for enhancing searches being performed by a search engine application, and monitoring data packets passing through a network node to identify a data packet containing an original search query; modifying the data packet containing the original search query to create a modified search query; and forwarding the modified search query to the search engine application in place of the original search query. | 10-30-2008 |
David A. Epstein, East Amherst, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20080286868 | METAL BINDING COMPOUNDS AND THEIR USE IN CELL CULTURE MEDIUM COMPOSITIONS - The present invention is directed generally to metal binding compounds which may be added to cell culture media to replace factors required for cultivation of the cells (e.g. transferrin) which are of animal or human origin. More specifically, the invention is directed to metal binding compounds or complexes thereof comprising one or more transition element cations (such as ferrous or ferric ions), which are added to cell and tissue culture medium compositions. The metal binding compounds may be added to the media alone or may be first complexed with a transition metal ion. The invention is also directed to methods of use of such compositions, including, for example, methods for the cultivation of eukaryotic cells, particularly animal cells, in vitro. The invention also relates to compositions comprising such culture media and one or more cells, and to kits comprising one or more of the above-described compositions. The compositions of the present invention obviate the need for naturally derived metal-binding proteins, such as transferrin and ceruloplasmin, which may contain blood-borne pathogens. | 11-20-2008 |
| 20090280532 | SERUM-FREE MAMMALIAN CELL CULTURE MEDIUM, AND USES THEREOF - The present invention provides a cell culture medium formulation that supports the in vitro cultivation, particularly in suspension, of mammalian cells, particularly epithelial cells and fibroblast cells, and methods for cultivating mammalian cells in suspension in vitro using these media. The media comprise a basal medium and a polyanionic or polyanionic compound, preferably a polysulfonated or polysulfated compound, and more preferably dextran sulfate. The present invention also provides chemically defined, protein-free eukaryotic cell culture media comprising an iron chelate and zinc, which is capable of supporting the growth (and particularly the high-density growth of mammalian cells) in suspension culture, increasing the level of expression of recombinant protein in cultured cells, and/or increasing virus production in cultured cells. | 11-12-2009 |
| 20090280533 | SERUM-FREE MAMMALIAN CELL CULTURE MEDIUM, AND USES THEREOF - The present invention provides a cell culture medium formulation that supports the in vitro cultivation, particularly in suspension, of mammalian cells, particularly epithelial cells and fibroblast cells, and methods for cultivating mammalian cells in suspension in vitro using these media. The media comprise a basal medium and a polyanionic or polyanionic compound, preferably a polysulfonated or polysulfated compound, and more preferably dextran sulfate. The present invention also provides chemically defined, protein-free eukaryotic cell culture media comprising an iron chelate and zinc, which is capable of supporting the growth (and particularly the high-density growth of mammalian cells) in suspension culture, increasing the level of expression of recombinant protein in cultured cells, and/or increasing virus production in cultured cells. | 11-12-2009 |
| 20110183375 | METAL BINDING COMPOUNDS AND THEIR USE IN CELL CULTURE MEDIUM COMPOSITIONS - The present invention is directed generally to metal binding compounds which may be added to cell culture media to replace factors required for cultivation of the cells (e.g. transferrin) which are of animal or human origin. More specifically, the invention is directed to metal binding compounds or complexes thereof comprising one or more transition element cations (such as ferrous or ferric ions), which are added to cell and tissue culture medium compositions. The metal binding compounds may be added to the media alone or may be first complexed with a transition metal ion. The invention is also directed to methods of use of such compositions, including, for example, methods for the cultivation of eukaryotic cells, particularly animal cells, in vitro. The invention also relates to compositions comprising such culture media and one or more cells, and to kits comprising one or more of the above-described compositions. The compositions of the present invention obviate the need for naturally derived metal-binding proteins, such as transferrin and ceruloplasmin, which may contain blood-borne pathogens. | 07-28-2011 |
David Alexander Epstein, Ossining, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20110055087 | Determining Cost and Processing of Sensed Data - Methods, systems and apparatus for determining a proposed cost for use of sensor resources and selecting a method of processing of sensed data are presented. Such a method includes the steps of: predicting a state of an environment, obtaining at least one criterion related to the use of the sensor resources comprising one or more data sensors, determining the proposed cost for use of the sensor resources, acquiring the sensed data from the one or more data sensors, determining a characteristic of the sensed data, and selecting the method of processing the sensed data according to the determined characteristic and the predicted state. The at least one criterion is based upon the predicted state. The determining of the proposed cost is based on the at least one criterion. One or more of steps are implemented on the processor device. | 03-03-2011 |
David M. Epstein, Huntington, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20090263397 | Combination anti-cancer therapy - The present invention provides a method for treating tumors or tumor metastases in a patient, comprising administering to said patient simultaneously or sequentially a therapeutically effective amount of a combination of an anti-cancer agent or treatment that elevates pAkt levels in tumor cells and an IGF-1R kinase inhibitor of Formula (I) (e.g. OSI-906). Examples of such anti-cancer agents or treatments include doxorubicin, cisplatin, and ionizing radiation. The present invention also provides a pharmaceutical composition comprising an anti-cancer agent that elevates pAkt levels in tumor cells and an IGF-1R kinase inhibitor of Formula (I), in a pharmaceutically acceptable carrier. The present invention also provides a method of identifying tumor cells that will respond most favorably to treatment with a combination of an anti-cancer agent or treatment that elevates pAkt levels in tumor cells and an IGF-1R kinase inhibitor. | 10-22-2009 |
| 20110275644 | BIOLOGICAL MARKERS PREDICTIVE OF ANTI-CANCER RESPONSE TO INSULIN-LIKE GROWTH FACTOR-1 RECEPTOR KINASE INHIBITORS - The present invention provides diagnostic methods for predicting the effectiveness of treatment of a cancer patient with an IGF-1R kinase inhibitor that inhibits both IGF-1R and IR kinases. Methods are provided for identifying patients with cancer who are likely to benefit from treatment with an IGF-1R kinase inhibitor that inhibits both IGF-1R and IR kinases. Methods are also provided for identifying patients with cancer who are likely to benefit from treatment with an IGF-1R kinase inhibitor that inhibits both IGF-1R and IR kinases, but who would likely not respond to therapy with an anti-IGF-1R antibody. Methods are also provided for identifying patients with cancer who are more likely to benefit from treatment with anti-IGF-1R antibody. Improved methods for treating cancer patients with IGF-1R kinase inhibitors that incorporate these methods are also provided. | 11-10-2011 |
Edward A. Epstein, Putnam Valley, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20090313026 | CONVERSATIONAL COMPUTING VIA CONVERSATIONAL VIRTUAL MACHINE - A conversational computing system that provides a universal coordinated multi-modal conversational user interface (CUI) | 12-17-2009 |
Joseph Charles Epstein, New York, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20100137049 | INTERACTIVE GUITAR GAME DESIGNED FOR LEARNING TO PLAY THE GUITAR - An interactive game designed for learning to play a guitar. A guitar may be connected to a computer or other platform, capable of loading music and displaying notes and chords and other feedback and visual learning aids on a display screen, allowing a user to read music and play along. The goal of the software or interactive game engine is for players to learn how to play a guitar. Users may operate the game in a number of modes with different goals, playing mini-games throughout the levels of the game. The game provides feedback and statistics to help users learn how to play the guitar. | 06-03-2010 |
Joseph W. Epstein, Monroe, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20080234354 | Methods And Compositions For Controlling Body Weight And Appetite - The present invention provides novel compositions and methods for the controlling appetite and weight and/or treating obesity using a (+)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane or related compound. The invention also provides novel compositions and methods for treating or preventing disorders related to or complicated by excessive body weight or obesity, including coronary heart disease, osteoarthritis, osteoporosis, dislipidemias, gout, atherosclerosis, joint pain, sexual and fertility problems, respiratory problems, gall bladder disease, skin conditions, hypertension, diabetes, stroke, pulmonary embolism, sleep apnea, idiopathic intracranial hypertension, lower extremity venous stasis disease, gastro-esophageal reflux, urinary stress incontinence, metabolic syndrome, insulin resistance and cancer. The methods and compositions of the invention may employ a (+)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane or related compound alone, or in combination with a second anti-appetite or anti-obesity agent. | 09-25-2008 |
Michael Epstein, Spring Valley, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20080256261 | Proximity Detection Method - The invention relates to a method of determining a proximity between a root node ( | 10-16-2008 |
| 20090003605 | TEMPORAL PROXIMITY TO VERIFY PHYSICAL PROXIMITY - A security system assesses the response time to requests for information to determine whether the responding system is in physical proximity to the requesting system. Generally, physical proximity corresponds to temporal proximity. If the response time indicates a substantial or abnormal lag between request and response, the system assumes that the lag is caused by the request and response having to travel a substantial or abnormal physical distance, or caused by the request being processed to generate a response, rather than being answered by an existing response in the physical possession of a user. If a substantial or abnormal lag is detected, the system is configured to limit subsequent access to protected material by the current user, and/or to notify security personnel of the abnormal response lag. | 01-01-2009 |
Michael A. Epstein, Spring Valley, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20090038016 | Detecting And Reacting To Protected Content Material In A Display Or Video Drive Unit - A system and method to protect content material enforce copy protection by establishing a secure link ( | 02-05-2009 |
| 20110258449 | SECURE PROXIMITY VERIFICATION OF A NODE ON A NETWORK - A system and method determines the proximity of the target node to the source node from the time required to communicate messages within the node-verification protocol. The node-verification protocol includes a query-response sequence, wherein the source node communicates a query to the target node, and the target node communicates a corresponding response to the source node. The target node is configured to communicate two responses to the query: a first response that is transmitted immediately upon receipt of the query, and a second response based on the contents of the query. The communication time is determined based on the time duration between the transmission of the query and receipt of the first response at the source node and the second response is compared for correspondence to the query, to verify the authenticity of the target node. | 10-20-2011 |
Robert Epstein, Upper Grandview, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20100217626 | System and Method for Clinical Strategy for Therapeutic Pharmacies - A system and method of distributing pharmaceutical prescriptions within a network of pharmacies based on the review of prescription claim data and patient medical state to enable stratification of patients, wherein each pharmacy within the network has been established to handle one or more particular patient medical states. | 08-26-2010 |