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Epperly

Mark S. Epperly, Sherrard, IL US

Patent application numberDescriptionPublished
20080205978Cable actuated pin latching mechanism with automatic cable tension and pin release features - A cable actuated pin latching mechanism adapted for releasably connecting a header to a feeder of a combine, which automatically maintains predetermined tension conditions on the cable during normal latching and unlatching operation, and when an actuator of the mechanism is held in an unlatch position with the latch pin stuck or restrained, applies and maintains a tension force for releasing the pin, for instance, to enable a user to move to the operator cab to operate lift, tilt and/or other controls, as required for freeing the pin.08-28-2008
20080207286Rotor for a threshing system of an agricultural combine and method of making the same - A rotor for a threshing system of an agricultural combine and method for making the same, including a main body segment made from a sheet formed into a tube and including specially shaped interlocking edges forming a serpentine joint routed locations where threshing element mounts attach to the rotor.08-28-2008
20080234018Rotor for a threshing system of an agricultural combine and method of making the same - A rotor for a threshing system of an agricultural combine and method for making the same, including a body of simplified, three part press fit construction including an inlet segment, a main body segment having threshing elements therearound, and a bulkhead to be connected to a drive mechanism. The inlet segment, main body segment and bulkhead are configured so as to facilitate press fit assembly thereof concentric about a rotational axis about which the rotor will be rotated during operation, while also minimizing eccentricities of those components. As a result, the manufacture of the rotor is simplified by the elimination of the need for an internal skeleton structure and associated welds and/or fasteners.09-25-2008

Michael Epperly, Pittsburgh, PA US

Patent application numberDescriptionPublished
20110172214USE OF TARGETED NITROXIDE AGENTS IN PREVENTING, MITIGATING AND TREATING RADIATION INJURY - Provided herein are compositions and related methods useful for free radical scavenging, with particular selectivity for mitochondria. The compounds comprise a nitroxide-containing group attached to a mitochondria-targeting group. The compounds can be cross-linked into dimers without loss of activity. Also provided herein are methods, for preventing, mitigating and treating damage caused by radiation. The method comprises delivering a compound, as described herein, to a patient in an amount and dosage regimen effective to prevent, mitigate or treat damage caused by radiation.07-14-2011

Michael Epperly, Mccandless, PA US

Patent application numberDescriptionPublished
20110288178RADIOPROTECTIVE AGENTS - Provided herein are methods, for reducing, preventing, mitigating and treating damage caused by radiation. The methods comprise delivering a compound, as described herein, to a patient in an amount and dosage regimen effective to prevent, mitigate or treat damage caused by radiation or to mitigate apoptosis. The compounds comprise glyburide or other sulfonylurea hypoglycemic compounds or potassium channel inhibitors.11-24-2011

Michael S. Epperly, Bear, DE US

Patent application numberDescriptionPublished
20090130435Intermetallic-containing composite bodies, and methods for making same - Composite bodies made by a silicon metal infiltration process that feature a silicon intermetallic, e.g., a metal silicide. Not only does this give the composite material engineer greater flexibility in designing or tailoring the physical properties of the resulting composite material, but the infiltrant also can be engineered compositionally to have much diminished amounts of expansion upon solidification, thereby enhancing net-shape-making capabilities. These and other consequences of engineering the metal component of composite bodies made by silicon infiltration permit the fabrication of large structures of complex shape.05-21-2009

Scott Epperly, East Bridgewater, MA US

Patent application numberDescriptionPublished
20090035346Methods and Compositions for Enhancing Vascular Access - Disclosed is an implantable material comprising a biocompatible matrix and cells which, when provided to a vascular access structure, can promote functionality generally. For example, implantable material of the present invention can enhance maturation of an arteriovenous native fistula as well as prolong the fistula in a mature, functional state suitable for dialysis. Additionally, the present invention can promote formation of a functional arteriovenous graft suitable for dialysis as well as promote formation of a functional peripheral bypass graft. Implantable material can be configured as a flexible planar form or a flowable composition with shape-retaining properties suitable for implantation at, adjacent or in the vicinity of an anastomoses or arteriovenous graft. According to the methods disclosed herein, the implantable material is provided to an exterior surface of a blood vessel. Certain embodiments of the flexible planar form define a slot. The materials and methods of the present invention comprise cells, preferably endothelial cells or cells having an endothelial-like phenotype.02-05-2009
20100204783METHODS AND COMPOSITIONS FOR ENHANCING VASCULAR ACCESS - Disclosed is an implantable material comprising a biocompatible matrix and cells which, when provided to a vascular access structure, can promote functionality.08-12-2010
20100318016Methods and Compositions for Enhancing Vascular Access - Disclosed is an implantable material comprising a biocompatible matrix and cells which, when provided to a vascular access structure, can promote functionality generally. For example, implantable material of the present invention can enhance maturation of an arteriovenous native fistula as well as prolong the fistula in a mature, functional state suitable for dialysis. Additionally, the present invention can promote formation of a functional arteriovenous graft suitable for dialysis as well as promote formation of a functional peripheral bypass graft. Implantable material can be configured as a flexible planar form or a flowable composition with shape-retaining properties suitable for implantation at, adjacent or in the vicinity of an anastomoses or arteriovenous graft. According to the methods disclosed herein, the implantable material is provided to an exterior surface of a blood vessel. Certain embodiments of the flexible planar form define a slot. The materials and methods of the present invention comprise cells, preferably endothelial cells or cells having an endothelial-like phenotype.12-16-2010
20110229549Methods and Compositions for Enhancing Vascular Access - Disclosed is an implantable material comprising a biocompatible matrix and cells which, when provided to a vascular access structure, can promote functionality generally. For example, implantable material of the present invention can enhance maturation of an arteriovenous native fistula as well as prolong the fistula in a mature, functional state suitable for dialysis. Additionally, the present invention can promote formation of a functional arteriovenous graft suitable for dialysis as well as promote formation of a functional peripheral bypass graft. Implantable material can be configured as a flexible planar form or a flowable composition with shape retaining properties suitable for implantation at, adjacent or in the vicinity of an anastomoses or arteriovenous graft. According to the methods disclosed herein, the implantable material is provided to an exterior surface of a blood vessel. Certain embodiments of the flexible planar form define a slot. The materials and methods of the present invention comprises cells, preferably endothelial cells or cells having an endothelial-like phenotype.09-22-2011

Patent applications by Scott Epperly, East Bridgewater, MA US

Scott Epperly, Torrance, CA US

Patent application numberDescriptionPublished
20120059424Clavicle Bone Plate - A bone plate for treating clavicle fractures. The bone plate may include an elongated body having one or more curved portions that roughly conform to the surface and/or anatomical curvature of the clavicle. One or more openings may be provided for receiving an anchoring member, such as a bone screw, for fastening at least a portion of the bone plate onto the clavicle. The bone plate may provide at least one rail member extending along a portion of the body of the bone plate. The bone plate, when affixed to the clavicle, permits the rail member to rest upon the outer surface of the clavicle, thus providing an area defining a cavity formed between an outer surface of the clavicle and a bottom surface of the body of the bone plate, and thus allowing blood to circulate against and around the clavicle.03-08-2012
20120059428Telescoping Bone Screw - A bone screw for treating a bone fracture having a plunger assembly and a detent assembly on a body portion thereof. The detent assembly includes a detent member that is movable between a first and second position. The plunger assembly includes a threaded engagement portion and a plunger portion. The plunger portion is slidably disposed within a chamber of the body. The detent assembly operative to secure the body whereby said plunger portion moves independent of said body.03-08-2012