| Patent application number | Description | Published |
| 20090263472 | ENDOTHELIN RECEPTOR ANTAGONIST DERIVATIVES - Endothelin receptor antagonist nitroderivatives of general formula (I): | 10-22-2009 |
| 20100041633 | NITRIC OXIDE RELEASING STEROIDS - The invention relates to nitrooxyderivative of corticosteroids of general formula (I) and pharmaceutically acceptable salts or stereoisomers thereof wherein R is a corticosteroid residue selected from: The compounds are useful in the treatment of respiratory diseases. | 02-18-2010 |
| 20100063035 | CARBONIC ANHYDRASE INHIBITORS DERIVATIVES - Nitroderivatives of dorzolamide and brinzolamide having improved pharmacological activity and enhanced tolerability are described. They can be employed for the treatment of glaucoma, ocular hypertension, age-related macular degeneration, diabetic macular edema, diabetic retinopathy, hypertensive retinopathy and retinal vasculopathies. | 03-11-2010 |
| 20100093685 | NITRIC OXIDE RELEASING STEROIDS - The invention relates to nitrooxyderivative of corticosteroids of general formula (I) and pharmaceutically acceptable salts or stereoisomers thereof | 04-15-2010 |
| 20100099729 | NITRIC OXIDE DONOR COMPOUNDS - The invention relates to nitric oxide donor compounds and their use for treating cardiovascular diseases, inflammation, pain, fever, gastrointestinal disorders, ophthalmic diseases, hepatic disorders, renal diseases, respiratory disorders, immunological diseases, bone metobolismsdysfunctions, central and peripheral nervous system diseases, sexual dysfunctions, infectious diseases, for the inhibition of platelet aggregation and platelet adhesion, for treating pathological conditions resulting from abnormal cell proliferation, vascular diseases. The invention also relates to compositions comprising at least one nitric oxide releasing compounds of the invention and composition comprising at least one nitric oxide releasing compounds according to the invention and at least one 15 therapeutic agent. | 04-22-2010 |
| 20110077279 | ANGIOTENSIN II RECEPTOR ANTAGONISTS - A compound having the structure | 03-31-2011 |
| 20110130376 | NEW NO RELEASING STEROIDS DERIVATIVES - The invention relates to compounds of general formula (I) and pharmaceutically acceptable salts or stereoisomers thereof | 06-02-2011 |
| 20110144073 | GLUCOCORTICOIDS ATTACHED TO NITRATE ESTERS VIA AN AROMATIC LINKER IN POSITION 21 AND THEIR USE IN OPHTHALMOLOGY - The invention relates to nitrooxy derivatives of fluocinolone acetonide, triamcinolone acetonide, betamethasone and beclomethasone, methods for their preparation, pharmaceutical compositions containing these compounds, and methods of using these compounds and compositions for treating diabetic macular edema, diabetic retinopathy, macular degeneration, age-related macular degeneration and other diseases of retina and macula lutea. | 06-16-2011 |
| Patent application number | Description | Published |
| 20080221073 | Nitrooxy Derivatives of Glucocorticoids - The invention relates to new steroids nitrooxyderivatives, to topical pharmaceutical formulations thereof, and their use for treating skin or mucosal membrane diseases or disorders. These new steroids nitrooxyderivatives have an improved pharmacological activity and enhanced local tolerability. | 09-11-2008 |
| 20090258849 | NITROOXY DERIVATIVES OF GLUCOCORTICOIDS - The invention relates to new steroids nitrooxyderivatives, to topical pharmaceutical formulations thereof, and their use for treating skin or mucosal membrane diseases or disorders. These new steroids nitrooxyderivatives have an improved pharmacological activity and enhanced local tolerability. | 10-15-2009 |
| 20090264393 | NITROOXY DERIVATIVES OF GLUCOCORTICOIDS - The invention relates to new steroids nitrooxyderivatives, to topical pharmaceutical formulations thereof, and their use for treating skin or mucosal membrane diseases or disorders. These new steroids nitrooxyderivatives have an improved pharmacological activity and enhanced local tolerability. | 10-22-2009 |
| 20090264394 | NITROOXY DERIVATIVES OF GLUCOCORTICOIDS - The invention relates to new steroids nitrooxyderivatives, to topical pharmaceutical formulations thereof, and their use for treating skin or mucosal membrane diseases or disorders. These new steroids nitrooxyderivatives have an improved pharmacological activity and enhanced local tolerability. | 10-22-2009 |