Enhong
Enhong Chen, Hefei CN
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20130261982 | METHOD AND SYSTEM OF DETERMINING EARTHQUAKE PARAMETERS, EARTHQUAKE SEARCH ENGINE - Methods for rapidly determining earthquake parameters of an earthquake include inputting a seismogram of the earthquake, searching concurrently in pre-established historical seismogram database and theoretical seismogram database by use of an approximate nearest neighbor search method, to find a set of seismograms similar to the input seismogram according to a preset similarity condition, and determining from the set of similar seismograms one or more seismograms matched with the input seismogram, and determining the earthquake parameters from the matched seismograms. With the present invention, it is possible to search in millions of seismograms and determine parameters for an earthquake in a few second, and thus realize rapid and even real-time estimation of earthquake parameters. | 10-03-2013 |
Enhong Chen, Anhui CN
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20140074639 | METHOD AND APPARATUS FOR HOLISTIC MODELING OF USER ITEM RATING WITH TAG INFORMATION IN A RECOMMENDATION SYSTEM - An approach is provided for a holistic framework to model user item rating with user generated tag information. A tagging manager determines one or more tags associated with one or more items, wherein the one or more tags are generated by one or more users. The tagging manager processes and/or facilitates a processing of the one or more tags to cause, at least in part, a generation of one or more semantic spaces. The one or more semantic spaces and/or one or more semantic concepts within the one or more semantic spaces represent one or more groupings of the one or more tags. The tagging manager determines one or more probability parameters that the one or more tags, the one or more users, the one or more items, or a combination thereof are associated with respective ones of the one or more semantic concepts in the semantic spaces. The tagging manager then processes and/or facilitates a processing of the one or more probability parameters to cause, at least in part, a calculation of predicted rating information with respect to the one or more tags, the one or more users, the one or more items, or a combination thereof. | 03-13-2014 |
Enhong Zhang, Beijing CN
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20080292685 | Transdermal Patch Containing Isosorbide Dinitrate and Bisoprolol - This invention relates to a transdermal patch in the form of a layer complex, comprising a backing layer, a drug-reservoir layer comprising pharmacologically active ingredients and pharmaceutically acceptable adjuvants, and a release liner covering the drug-reservoir layer, characterized in that the drug-reservoir layer comprises isosorbide dinitrate and Bisoprolol at a ratio of 1:3 to 3:1 by weight, as the pharmacologically active ingredients. Animal tests show that said patch can reduce the elevation of T wave of cardiogram, the increase of the level of myocardial enzyme in blood serum, and the extension of the range of myocardial infarction caused by ligating the coronary artery in animals. Results show that said patch exhibits a considerable synergistic effect in the treatment of cardiovascular diseases and has good preventive and therapeutic effects on several adverse events on heart. In addition, the animal tests show that the patch according to the invention has a better pressure-reducing effect than the application of the patch containing only one of isosorbide dinitrate and Bisoprolol, and does not worsen the arrhythmia that is easily caused by the application of the patch containing only isosorbide dinitrate or Bisoprolol. | 11-27-2008 |
20110027345 | COMPOSITION CONTAINING ROTIGOTINE AND USE THEREOF AND TRANSDERMAL PATCH CONTAINING THE COMPOSITION - The present invention relates to a composition containing Rotigotine and the use thereof in the manufacture of a Rotigotine-containing transdermal patch, wherein said composition is based on a matrix mixture system formed from a combination of an acrylic pressure-sensitive adhesive with a silicone pressure-sensitive adhesive, and polyvinylpyrrolidone which are present in a particular weight ratio, wherein (1) the acrylic pressure-sensitive adhesive is present in an amount of about 1-25% by weight in the matrix mixture system, (2) the silicone pressure-sensitive adhesive is present in an amount of about 65-98% by weight in the matrix mixture system, and (3) the polyvinylpyrrolidone is present in an amount of about 1-10% by weight in the matrix mixture system, and comprises 1-40% of Rotigotine on the basis of the total weight of the composition. The present invention further relates to an improved transdermal patch containing Rotigotine comprising said composition. Said patch has improved properties in the solubility, release and initial penetration level of Rotigotine. | 02-03-2011 |