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Engelhardt, US
Ashley E. Engelhardt, Greenwood, IN US
| Patent application number | Description | Published |
|---|---|---|
| 20100051502 | CARRIER HAVING INTEGRAL DETECTION AND MEASUREMENT OF ENVIRONMENTAL PARAMETERS - A carrier includes an enclosure for storing articles sensitive to electrostatic discharge (ESD) and a replacement component that is affixed to the enclosure as an integral component of the carrier. The replacement component includes a housing that provides an enclosure for a device having a sensor for sensing one or more environmental parameters. At least one of the sensed environmental parameters is an ESD parameter. | 03-04-2010 |
Barbara Engelhardt, San Francisco, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110060736 | Query Revision Using Known Highly-Ranked Queries - An information retrieval system includes a query revision architecture providing one or more query revisers, each of which implements a query revision strategy. A query rank reviser suggests known highly-ranked queries as revisions to a first query by initially assigning a rank to all queries, and identifying a set of known highly-ranked queries (KHRQ). Queries with a strong probability of being revised to a KHRQ are identified as nearby queries (NQ). Alternative queries that are KHRQs are provided as candidate revisions for a given query. For alternative queries that are NQs, the corresponding known highly-ranked queries are provided as candidate revisions. | 03-10-2011 |
Dean Engelhardt, New York, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20100273145 | ASSAY METHOD UTILIZING POLYNUCLEOTIDE SEQUENCES - A method of detecting in a sample an analyte (A) having a molecularly recognizable portion thereon, which comprises: providing (B) a molecular bridging entity having thereon: (i) a portion capable of recognizing the molecularly recognizable portion on the analyte; and (ii) a portion comprising a polynucleotide sequence; and (C) a signalling entity having thereon: (i) a polynucleotide portion capable of annealing to the polynucleotide portion of the bridging entity, thereby to form a stable polynucleotide hybrid, and (ii) a signal generating portion; forming a complex comprising: (1) the analyte (A) complexed through its molecularly recognizable portion to (2) the recognizing portion of the entity (B); the entity (B) being complexed through the polynucleotide portion thereon to (3) the polynucleotide portion of the signalling entity; and detecting a signal by means of the signal generating portion present in the complex. | 10-28-2010 |
Dean L. Engelhardt, New York, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20080248564 | NOVEL PROPERTY EFFECTING AND/OR PROPERTY EXHIBITING COMPOSITIONS FOR THERAPEUTIC AND DIAGNOSTIC USES - The present invention provides an array of compositions useful for effecting and/or exhibiting changes in biological functioning and processing within cells and in biological systems containing such cells. In effect, these compositions combine chemical modifications and/or ligand additions with biological functions. The chemical modifications and/or ligand additions provide additional characteristics to the compositions without interfering substantially with their biological function. Such additional characteristics include nuclease resistance, targeting specific cells or specific cell receptors localizing to specific sites within cells and augmenting interactions between the compositions and target cells of interest as well as decreasing such interactions when desired. Also provided by the present invention are processes and kits. | 10-09-2008 |
| 20090068731 | Novel process, construct and conjugate for producing multiple nucleic acid copies - This invention provides inter alia an in vitro process for producing multiple specific nucleic acid copies in which the copies are produced under isostatic conditions, by degradation of primer sequences from extended primers, thereby allowing subsequent priming events on the same template. | 03-12-2009 |
| 20100021500 | Processes for treating subjects carrying viral infectious agent - This invention provides novel processes for therapeutic applications, including the treatment of subjects carrying infectious agents or having impaired autoimmunity or impaired immune condition. The therapeutic applications disclosed herein are also directed at the treatment of cancerous subjects with malignant tumors containing cancerous cells or malignant or cancerous cells. Vaccination processes for preventing infections in subjects are also provided. The novel processes comprise introducing into or adminstering to a subject one or more antigens, or trained or adopted immune cells. These antigens or immune cells are capable of establishing or increasing at least one first specific immune response and decreasing at least one second specific immune response. Such responses include components, such as cellular immune reaction elements, humoral immune reaction elements and cytokines, the latter also encompassing interferons and lymphokines. Useful compositions are also provided by this invention. | 01-28-2010 |
| 20110097791 | Novel process, construct and conjugate for producing multiple nucleic acid copies - This invention provides inter alia an in vitro process for producing multiple specific nucleic acid copies in which the copies are produced under isostatic conditions, e.g., temperature, buffer and ionic strength, and independently of any requirement for introducing an intermediate structure for producing the copies. In other aspects, the invention provides in vitro processes for producing multiple specific nucleic acid copies in which the products are substantially free of any primer-coded sequences, such sequences having been substantially or all removed from the product to regenerate a primer binding site, thereby allowing new priming events to occur and multiple nucleic acid copies to be produced. This invention further provides a promoter-independent non-naturally occurring nucleic acid construct that produces a nucleic acid copy or copies without using or relying on any gene product that may be coded by the nucleic acid construct. Another aspect of this invention concerns a protein-nucleic acid construct in the form of a conjugate linked variously, e.g., covalent linkage, complementary nucleic acid base-pairing, nucleic acid binding proteins, or ligand receptor binding. Further disclosed in this invention is an in vivo process for producing a specific nucleic acid in which such a protein-nucleic acid construct conjugate is introduced into a cell. A still further aspect of the invention relates to a construct comprising a host promoter, second promoter and DNA sequence uniquely located on the construct. The host transcribes a sequence in the construct coding for a different RNA polymerase which after translation is capable of recognizing its cognate promoter and transcribing from a DNA sequence of interest in the construct with the cognate promoter oriented such that it does not promote transcription from the construct of the different RNA polymerase. | 04-28-2011 |
Jeffrey S. Engelhardt, Jacksonville, FL US
| Patent application number | Description | Published |
|---|---|---|
| 20120030240 | ENTERPRISE CONTENT MANAGEMENT FEDERATION AND INTEGRATION SYSTEM - An enterprise content management federation and integration system integrates a plurality of applications and federates information seamlessly by receiving, by a composite system, a request from a client system. The system then translates, by a manager system, the request from the client system. The manager system performs one or more high level validations and retrieves information from a mapping stored by an ontology modeling system, a plurality of content types, repositories, actions and object types based at least in part on a plurality of attributes including one or more metadata models or attribute models. The manager system then invokes one or more composites based at least in part on the request from the client system and some or all the information retrieved from the mapping. | 02-02-2012 |
John Engelhardt, Iowa City, IA US
| Patent application number | Description | Published |
|---|---|---|
| 20090241203 | Transgenic animal models of disease - The present invention provides transgenic, large non-human animal models of diseases and conditions, as well as methods of making and using such animal models in the identification and characterization of therapies for the diseases and conditions. | 09-24-2009 |
John Engelhardt, Greenwich, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20080297162 | Electrical Instrument Platform for Mounting on and Removal from an Energized High Voltage Power Conductor - An apparatus for monitoring and measuring the electrical, thermal and mechanical operating parameters of high voltage power conductors. A toroidal shaped housing, which can be mounted onto an energized conductor, contains all of the necessary electrical instruments to monitor the parameters associated with the conductor. Moreover, the housing includes the processing capability to analyze disturbance and fault events based on these parameters. | 12-04-2008 |
| 20090138229 | POWER LINE TEMPERATURE AND SAG MONITOR SYSTEM - The combination of a temperature sensor and an inclination sensor or the combination of a temperature sensor and a tension monitor properly positioned in conjunction with an energized electrical conductor produces outputs that are dependent on the conductor's average temperature in real time. A transmitter is used to communicate this information in real time to a central location such that up to optimal or maximum power transmission is feasible through the conductor while maintaining a safe clearance to the ground. This allows for close monitoring of thermal expansion resulting from increased load as well as varying environmental conditions. | 05-28-2009 |
Johnnie Engelhardt, West Columbia, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20120108469 | APPARATUS FOR COMBINATORIAL SYNTHESIS - Apparatus and methods are described for split synthesis combinatorial chemistry that provides candidate libraries where an even distribution of theoretical products is obtainable through even mixing during the pooling step, followed by controlled redistribution of the mixed pooled products from the prior addition step into separate synthesis columns, one for each different specie of subunit to be added. | 05-03-2012 |
Michael Thomas Engelhardt, Sunnyvale, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110037446 | SWITCH MODE POWER SUPPLY WITH DYNAMIC TOPOLOGY - A power supply system has an inductive device, a plurality of switching devices for providing connection of the inductive device to input and output nodes and a ground node, and a switch driver circuit for driving the switching devices so as to enable the power supply to operate in a boost mode to increase the input voltage, in a buck mode to decrease the input voltage, and in a solid-state flyback mode to transfer between the boost mode and the buck mode. In the solid-state flyback mode, the switching devices are controlled to provide switching of the inductive device between an input state in which the inductive device is connected between the input node and the ground node, and an output state in which the inductive device is connected between the ground node and the output node. | 02-17-2011 |
Michel Engelhardt, Woodbury, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20110196540 | ENVIRONMENTAL CONTROL SYSTEM FOR PRECISION AIRBORNE PAYLOADS - Outside air enters a ram air scoop on an aircraft frame, and is ducted to a ram air control valve. The air control valve outputs a desired air mass flow to a cyclone air-water separator which removes moisture and produces a dry air flow. A heater assembly heats the dry air to a desired temperature and directs the heated air into an equipment bay enclosure on the aircraft. The relative humidity of the heated air is sensed by an air moisture sensor which produces a corresponding signal. Other sensors disposed near a payload in the bay enclosure produce corresponding air temperature and air pressure signals. All the sensor signals are input to a processor or controller configured to activate the air control valve and the heater assembly according to set points for temperature and humidity that are specified for the payload in the bay enclosure. | 08-11-2011 |