Patent application number | Description | Published |
20130008724 | DRILL BIT WITH DISTRIBUTED FORCE PROFILE - A method of making a drill bit for drilling subterranean formations includes forming a first blade having a shape and configuration defined by one or more first parameters and forming a second blade having a shape and configuration defined by one or more second parameters. One of the first parameters is different than one of the second parameters. | 01-10-2013 |
20130035902 | METHODS OF DESIGNING EARTH-BORING TOOLS USING A PLURALITY OF WEAR STATE VALUES AND RELATED METHODS OF FORMING EARTH-BORING TOOLS - Methods of designing an earth-boring tool are described, including calculating one or more performance parameters based on drilling conditions, a plurality of wear state values, and a set of values of other design variables. Methods of enhancing a performance parameter in the design of an earth-boring tool are also described, including calculating the performance parameter based at least partially on a plurality of wear state values and a first set of values of other design variables, calculating the performance parameter based at least partially on the plurality of wear state values and a second set of values of design variables different than the first set, and comparing the calculated performance parameters to determine which of the first and the second set is closer to a target range or value across a range of the plurality of wear state values. Related methods of forming an earth-boring tool are also described. | 02-07-2013 |
20130035903 | METHODS OF DESIGNING EARTH-BORING TOOLS USING A PLURALITY OF DEPTH OF CUT VALUES AND RELATED METHODS OF FORMING EARTH-BORING TOOLS - Methods of designing an earth-boring tool are described, including calculating one or more performance parameters of the tool based on drilling conditions, a plurality of depth of cut values, and a set of values of other design variables. Methods of enhancing a performance parameter in the design of an earth-boring tool are also described, including calculating the performance parameter based at least partially on a plurality of depth of cut values and a first set of values of other design variables, calculating the performance parameter based at least partially on a second set of values of the other design variables different than the first set, and comparing the calculated performance parameters to determine which of the first and the second set is closer to a target range or value across a range of the plurality of depths of cut. Related methods of forming an earth-boring tool are also described. | 02-07-2013 |
20150122547 | METHOD TO MITIGATE BIT INDUCED VIBRATIONS BY INTENTIONALLY MODIFYING MODE SHAPES OF DRILL STRINGS BY MASS OR STIFFNESS CHANGES - A method for reducing drill tubular vibrations includes: constructing a mathematical model the drill tubular having mass distribution, material stiffness and material damping; constructing an equation of motion of the drill tubular in one of a time domain and frequency domain; transforming the equation of motion into a modal domain equation of motion to provide a mode shape of the drill tubular at an eigenfrequency, the mode shape providing an amplitude at a position along the drill tubular; comparing the amplitude at the position along the drill tubular to a threshold amplitude value; modifying at least one of the mass distribution, material stiffness and material damping if the amplitude exceeds the threshold value; and iterating the above step until at least one of the amplitude of the latest mode shape at the position is less than or equal to the threshold amplitude value and a predetermined constraint limits the modifying. | 05-07-2015 |
Patent application number | Description | Published |
20090324622 | ANTIBODY VACCINE CONJUGATES AND USES THEREFOR - The present invention provides novel antibody vaccine conjugates and methods of using the same to induce a cytotoxic T cell (CTL) response. In a particular, embodiment, the vaccine conjugate includes a human chorionic gonadotropin beta subunit (βhCG) antigen linked to an anti-mannose receptor (MR) antibody. | 12-31-2009 |
20100272746 | LIPOPARTICLE COMPRISING A PROTEIN AND METHODS OF MAKING AND USING THE SAME - Enveloped virus vectors are described which comprise a cellular virus receptor protein and which are capable of fusing with a cell which comprises a viral envelope protein to which the cellular virus receptor protein is cognate. Enveloped virus vectors comprising a plurality of cellular virus receptor proteins are also described. Methods for making the enveloped virus vectors are described, as are methods of using the enveloped virus vectors. The invention further relates to a lipoparticle comprising a membrane spanning protein, and the lipoparticle can be attached to a sensor surface. The invention relates to methods of producing and using the lipoparticle to, inter alia, assess protein binding interactions. | 10-28-2010 |
20120039869 | METHODS OF USING MOLECULAR CONJUGATES COMPRISING MONOCLONAL ANTIBODIES TO DENDRITIC CELLS - The present invention provides novel methods for targeting an antigen to a dendritic cell using an antibody linked to the antigen. The present invention further provides methods of inducing or enhancing an immune response and methods of immunization using an antibody linked to the antigen. | 02-16-2012 |
20120148596 | MOLECULAR CONJUGATES COMPRISING HUMAN MONOCLONAL ANTIBODIES TO DENDRITIC CELLS - Isolated human monoclonal antibodies and antigen-binding portions thereof which specifically bind to dendritic cells are disclosed. Also disclosed are bispecifics, immunotoxins and antigen conjugates which include the antibodies or antibody portions. The human antibodies can be produced in a non-human transgenic animal, e.g., a transgenic mouse, capable of producing multiple isotypes of human monoclonal antibodies by undergoing V-D-J recombination and isotype switching. Also disclosed are pharmaceutical compositions comprising the human antibodies, non-human transgenic animals and hybridomas which produce the human antibodies, and therapeutic and diagnostic methods for using the human antibodies. | 06-14-2012 |
20120195882 | LIPOPARTICLE COMPRISING A PROTEIN AND METHODS OF MAKING AND USING THE SAME - Enveloped virus vectors are described which comprise a cellular virus receptor protein and which are capable of fusing with a cell which comprises a viral envelope protein to which the cellular virus receptor protein is cognate. Enveloped virus vectors comprising a plurality of cellular virus receptor proteins are also described. Methods for making the enveloped virus vectors are described, as are methods of using the enveloped virus vectors. The invention further relates to a lipoparticle comprising a membrane spanning protein, and the lipoparticle can be attached to a sensor surface. The invention relates to methods of producing and using the lipoparticle to, inter alia, assess protein binding interactions. | 08-02-2012 |
20160024192 | MOLECULAR CONJUGATES COMPRISING HUMAN MONOCLONAL ANTIBODIES TO DENDRITIC CELLS - Isolated human monoclonal antibodies and antigen-binding portions thereof which specifically bind to dendritic cells are disclosed. Also disclosed are bispecifics, immunotoxins and antigen conjugates which include the antibodies or antibody portions. The human antibodies can be produced in a non-human transgenic animal, e.g., a transgenic mouse, capable of producing multiple isotypes of human monoclonal antibodies by undergoing V-D-J recombination and isotype switching. Also disclosed are pharmaceutical compositions comprising the human antibodies, non-human transgenic animals and hybridomas which produce the human antibodies, and therapeutic and diagnostic methods for using the human antibodies. | 01-28-2016 |
Patent application number | Description | Published |
20080210260 | Multipurpose Aqueous Parts Washer - The present disclosure relates generally to a multipurpose parts washer used to remove grease, oil, and dirt from mechanical parts, and more particularly, to an apparatus for washing parts within a single housing having an automatic cleaning portion, with a first cleaning chamber for spraying parts, a second cleaning chamber for soaking and agitating parts, and a manual cleaning portion. The multipurpose parts washer includes three cleaning portions. All portions use cleaning solution from a single pump, a reservoir portion to collect and store the important volume of cleaning solution and debris from the washing process, a single controller interface operated from a display, and a thermal energy source for heating the cleaning solution. The multipurpose design also includes novel features such as the use of a submerged pump within the reservoir, easy-access panels for the pump motor, the controller, and the display, an integrated sink serving as a safety lid of the automatic portion to collect the cleaning solution of the manual cleaning portion and to enclose the automatic cleaning portion, and the use of a timer and a multicolor display for easy operation of each of the cleaning portions. The design may also include a concurrent multifunction cleaning feature, a thermally activated safety lid, an immersion agitation tank, and a removable flat or V-shaped debris pan. | 09-04-2008 |
20080210276 | Multipurpose Aqueous Parts Washer - The present disclosure relates generally to a multipurpose parts washer used to remove grease, oil, and dirt from mechanical parts, and more particularly, to an apparatus for washing parts within a single housing having an automatic cleaning portion, with a first cleaning chamber for spraying parts, a second cleaning chamber for soaking parts, and a manual cleaning portion. The multipurpose parts washer includes three cleaning portions. All portions use cleaning solution from a single pump, a reservoir portion to collect and store the important volume of cleaning solution and debris from the washing process, a single controller interface operated from a display, and a thermal energy source for heating the cleaning solution. The multipurpose design also includes novel features such as the use of a submerged pump within the reservoir, easy-access panels for the pump motor, the controller, and the display, an integrated sink serving as a lid of the automatic portion to collect the cleaning solution of the manual cleaning portion and to enclose the automatic cleaning portion, and the use of a timer and a multicolor display for easy operation of each of the cleaning portions. | 09-04-2008 |
20120291828 | MULTIPURPOSE AQUEOUS PARTS WASHER - A multipurpose parts washer used to remove grease, oil, and dirt from mechanical parts may include an automatic cleaning portion, a first cleaning chamber for spraying parts, a second cleaning chamber for soaking parts, and a manual cleaning portion. A controller for selectively operating the automatic cleaning portion may also be included. Displays may be connected to the controller to illustrate various states. All portions use cleaning solution from a single pump, a reservoir portion to collect and store a volume of cleaning solution and debris from the washing process, and a thermal energy source for heating the cleaning solution. | 11-22-2012 |
Patent application number | Description | Published |
20100227484 | MODULAR WIRING SYSTEM WITH LOCKING ELEMENTS - A wiring system includes a wiring module and a functional module. The wiring module in at least one embodiment includes elongated holes or openings which are configured to engage or lock with prongs on a functional module to create a lockable connection. The wiring module and the functional module form both a physical and an electrical connection. In another embodiment, the wiring module has at least three elongated openings or holes, and wherein one of the openings or holes is for receiving a ground prong, while the other openings or holes are for receiving prongs which conduct electricity or communicate information. In another embodiment there is a wiring module that has four elongated openings or holes with all four of these connections associated with the four elongated openings or holes configured to conduct electricity. | 09-09-2010 |
20110205698 | MODULAR WIRING SYSTEM WITH LOCKING ELEMENTS - A wiring system includes a wiring module and a functional module. The wiring module in at least one embodiment includes elongated holes or openings which are configured to engage or lock with prongs on a functional module to create a lockable connection. The wiring module and the functional module form both a physical and an electrical connection. In another embodiment, there is an adapter which is configured to connect the wiring module and the functional module or unit together. | 08-25-2011 |
20130029514 | MODULAR WIRING SYSTEM - In at least one embodiment, there is an electrical device comprising a functional module comprising a housing having a front face and a back face, and at least three arcuate blades extending out from the housing. At least one of the at least three arcuate blades has a locking section. The functional module can be used in a wiring system comprising at least one wiring module. The wiring module can include a housing having a front face and a back face and at least one opening for receiving at least one of the at least three arcuate blades. The disclosure can also include a wiring module which can be used separately from the functional module wherein the wiring module includes a housing having at least one movable arm. Inside the wiring module is a plurality of contacts disposed in the housing, wherein these contacts are configured to couple to electrical wiring. | 01-31-2013 |
20130135828 | MODULAR WIRING SYSTEM - In at least one embodiment, there is an electrical device comprising a functional module comprising a housing having a front face and a back face, and at least three arcuate blades extending out from the housing. At least one of the arcuate blades has a locking section. The functional module can be used in a wiring system comprising at least one wiring module. The wiring module can include a housing having a front face and a back face and at least one opening for receiving at least one of the at least three arcuate blades. The disclosure can also include a wiring module which can be used separately from the functional module wherein the wiring module includes a housing having at least one movable arm. Inside the wiring module is a plurality of contacts disposed in the housing, wherein these contacts are configured to couple to electrical wiring. | 05-30-2013 |
Patent application number | Description | Published |
20090284601 | APPARATUS FOR INTELLIGENT AND AUTONOMOUS VIDEO CONTENT GENERATION AND STREAMING - A system for automatically capturing an event of interest in a venue is disclosed, comprising a plurality of cameras for capturing video images of the event; and at least one processor communicatively connected to said plurality of cameras and con figured to execute a plurality of modules, said modules comprising a rectification module for combining the video images to form a wide-angle view; at least one of a motion analysis module configured for tracking salient blobs that are not part of a background of the wide-angle view, an activity analysis module configured for extracting temporal and spatial patterns from the wide-angle view, and a shape and appearance module configured for selecting one or more objects in the wide-angle view based on descriptors that are scale and rotational invariant; and a region of interest selector for selecting a viewpoint from the wide-angle view based on output from at least one of the motion analysis module, the activity analysis module, and the shape and appearance module, wherein the region of interest selector outputs the selected viewpoint for display. The system further comprises at least one audio recording device for capturing audio from the event; and means for synchronizing the video images and audio. | 11-19-2009 |
20130182119 | APPARATUS FOR INTELLIGENT AND AUTONOMOUS VIDEO CONTENT GENERATION AND STREAMING - A system for automatically capturing an event of interest in a venue is disclosed, comprising a plurality of cameras for capturing video images of the event; and at least one processor communicatively connected to said plurality of cameras and configured to execute a plurality of modules, said modules comprising a rectification module for combining the video images to form a wide-angle view; at least one of a motion analysis module configured for tracking salient blobs that are not part of a background of the wide-angle view, an activity analysis module configured for extracting temporal and spatial patterns from the wide-angle view, and a shape and appearance module configured for selecting one or more objects in the wide-angle view based on descriptors that are scale and rotational invariant; and a region of interest selector for selecting a viewpoint from the wide-angle view based on output from at least one of the motion analysis module, the activity analysis module, and the shape and appearance module, wherein the region of interest selector outputs the selected viewpoint for display. The system further comprises at least one audio recording device for capturing audio from the event; and means for synchronizing the video images and audio. | 07-18-2013 |