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Embrechts

Mark J. Embrechts, Clifton Park, NY US

Patent application numberDescriptionPublished
20110047105Use of Machine Learning for Classification of Magneto Cardiograms - The use of machine learning for pattern recognition in magnetocardiography (MCG) that measures magnetic fields emitted by the electrophysiological activity of the heart is disclosed herein. Direct kernel methods are used to separate abnormal MCG heart patterns from normal ones. For unsupervised learning, Direct Kernel based Self-Organizing Maps are introduced. For supervised learning Direct Kernel Partial Least Squares and (Direct) Kernel Ridge Regression are used. These results are then compared with classical Support Vector Machines and Kernel Partial Least Squares. The hyper-parameters for these methods are tuned on a validation subset of the training data before testing. Also investigated is the most effective pre-processing, using local, vertical, horizontal and two-dimensional (global) Mahanalobis scaling, wavelet transforms, and variable selection by filtering.02-24-2011

Roger Embrechts, Beerse BE

Patent application numberDescriptionPublished
20090111872STABILIZED PEDIATRIC SUSPENSION OF CARISBAMATE - The present invention provides a stabilized pharmaceutical suspension of carisbamate for pediatric and adult use. More particularly, the suspension is stabilized with hypromellose (HPMC) to prevent crystal growth of the suspended particles and to prevent re-crystallization of the drug product with change in polymorphic form.04-30-2009

Roger Carolus Augusta Embrechts, Oud-Turnhout BE

Patent application numberDescriptionPublished
20080234291Mitratapide Oral Solution - The present invention concerns an oral solution comprising the MTP inhibitor mitratapide or an pharmaceutically acceptable acid addition salt thereof, a process for preparing such solutions, and their use in the treatment of MTP-related disorders such as hyperlipidemia, obesity, or type II diabetes.09-25-2008

Werner Constant John Embrechts, Beerse BE

Patent application numberDescriptionPublished
20100152174MACROCYCLIC QUINAZOLE DERIVATIVES AND THEIR USE AS MTKI - The present invention concerns the compounds of formula (I), the N-oxide forms, the pharmaceutically acceptable addition salts and the stereochemically isomeric forms thereof, wherein Z represents NH; Y represents —C06-17-2010