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Elzbieta

Elzbieta Hejchman, Warsaw PL

Patent application numberDescriptionPublished
20090270496ANTIFUNGAL COMPOUNDS - Antifungal compounds having a benzofuran structure. Antifungals exhibit much less toxicity to human cells than amiodarone. These compounds are useful alone or in combination with other compounds having antifungal activity. Compounds of this invention exhibit synergistic antifungal activity in combination with antifungal amiodarone compounds. The invention provides pharmaceutical compositions useful for treating fungal infections, methods for treating fungal infections and compounds useful in such compositions for treating fungal infections. Compounds of this invention are further useful as antifungal agents for the prevention and or treatment of fungal infections in plants. The invention includes agriculturally useful compositions comprising one or more compounds of this invention which exhibit fungistatic or fungicidal function against one or more plant pathogen is a fungus.10-29-2009

Elzbieta Izbicka, San Antonio, TX US

Patent application numberDescriptionPublished
20090068685Method of Identifying Biomarkers in Human Serum Indicative of Pathologies of Human Lung Tissues - A method of identifying altered biomarker expression levels in a human serum specimen to diagnose asthma or non-small celled lung cancers in humans. The existence of asthma or non-small celled lung cancers in a patient can be determined by subjecting a blood sample from the patient to a simple blood test to determine the expression levels of certain specific biomarkers. The expression levels of the specific biomarkers are compared to ranges of expression levels for the same biomarkers which are indicative of individuals known to have asthma, non-small cell lung cancers, or neither. Comparing the expression levels will determine the existence or non-existence of asthma or non-small cell lung cancer.03-12-2009
20090069189METHOD OF IDENTIFYING PROTEINS IN HUMAN SERUM INDICATIVE OF PATHOLOGIES OF HUMAN LUNG TISSUES - A method of identifying proteins present in human serum which are differentially expressed between normal individuals and patients known to have non-small cell lung cancers and asthma, as diagnosed by a physician. Human serum specimens from each population are digested with trypsin or any other suitable endoproteinase and analyzed using a liquid chromatography electrospray ionization mass spectrometer. Mass spectral data from each population is compared to determine proteins with expression intensities which are significantly differentially expressed between the normal, asthma, and lung cancer populations. Eleven proteins are found to have expression intensities which are significantly differentially expressed between the populations. Finally, the identities of the eleven proteins are obtained by comparing the mass spectral data with known databases having libraries of mass spectral data of known proteins.03-12-2009
20100009386METHODS OF IDENTIFICATION, ASSESSMENT, PREVENTION AND THERAPY OF LUNG DISEASES AND KITS THEREOF - The invention provides biomarkers and combinations of biomarkers that are useful in diagnosing lung diseases such as non-small cell lung cancer or reactive airway disease. The invention also provides methods of differentiating lung disease, methods of monitoring therapy, and methods of predicting a subject's response to therapeutic intervention based on the extent of expression of the biomarkers and combinations of biomarkers. Kits comprising agents for detecting the biomarkers and combination of biomarkers are also provided.01-14-2010

Elzbieta Izbicka, Marion, TX US

Patent application numberDescriptionPublished
20090326069Azelaic acid ester compositions and methods for diagnosing and treating tissue conditions using azelaic acid ester compositions and proteinaceous biomarkers - Therapeutic and cosmetic treatments are performed through the application of azelaic acid ester compositions to patients suffering from or exhibiting tissue inflammation. The diagnosis, characterization and treatment of a patient suffering from or exhibiting tissue inflammation may be enhanced by using selected proteinaceous biomarkers obtained from analysis of said markers by means of multiplexed immunoassay and comparison to the biomarker levels of healthy tissue.12-31-2009

Elzbieta Mietkiewska, Edmonton CA

Patent application numberDescriptionPublished
20100122377LUNARIA ANNUA,CARDAMINE GRAECA AND TEESDALIA NUDICAULIS FAE GENES AND THEIR USE IN PRODUCING NERVONIC AND EICOSENOIC ACIDS IN SEED OILS - This invention relates to nucleic acid sequences coding for a 05-13-2010

Elzbieta Mietkiewska, Saskatoon CA

Patent application numberDescriptionPublished
20090293145Acyl-coa-dependent diacylglycerol acyltransferas 1 (dgat1) gene from tropaeolum majus, protein encoded thereby and uses thereof - A diacylglycerol acyltransferase (DGAT1) gene from 11-26-2009

Elzbieta Nahrstedt, Nieder-Olm DE

Patent application numberDescriptionPublished
20090161108Measurement Chip - The present invention concerns a measurement chip (06-25-2009