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Els
Els Fieremans, New York, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20120002851 | System, Method and Computer Accessible Medium for Providing Real-Time Diffusional Kurtosis Imaging and for Facilitating Estimation of Tensors and Tensor- Derived Measures in Diffusional Kurtosis Imaging - Exemplary method, system, and computer-accessible medium can be provided for determining a measure of diffusional kurtosis by receiving data relating to at least one diffusion weighted image, and determining a measure of a diffusional kurtosis as a function of the received data using a closed form solution procedure. In accordance with certain exemplary embodiments of the present disclosure, provided herein are computer-accessible medium, systems and methods for, e.g., imaging in an MRI system, and, more particularly for facilitating estimation of tensors and tensor-derived measures in diffusional kurtosis imaging (DKI). For example, DKI can facilitate a characterization of non-Gaussian diffusion of water molecules in biological tissues. The diffusion and kurtosis tensors parameterizing the DKI model can typically be estimated via unconstrained least squares (LS) methods. In the presence of noise, motion, and imaging artifacts, these methods can be prone to producing physically and/or biologically implausible tensor estimates. The exemplary embodiments of the present disclosure can address at least this deficiency by formulating an exemplary estimation problem, e.g., as linearly constrained linear LS, where the constraints can ensure acceptable tensor estimates. | 01-05-2012 |
Els Henckaerts, New York, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20090300782 | Targeted gene addition in stem cells - The present invention provides methods for adenoassociated virus-mediated site-specific integration of a transgene into a stem cell. Stem cells having a transgene integrated therein, and differentiated cells generated from the stem cells are also provided. | 12-03-2009 |
Els Kesters, Holsbeek BE
| Patent application number | Description | Published |
|---|---|---|
| 20100071718 | Method for Removing a Hardened Photoresist - A method for removing a hardened photoresist from a semiconductor substrate. An example method for removing a hardened photoresist layer from a substrate comprising a low-κ dielectric material preserving the characteristics of the low-k dielectric material includes: a)—providing a substrate comprising a hardened photoresist layer and a low-κ dielectric material at least partially exposed; b)—forming C═C double bonds in the hardened photoresist by exposing the hardened photoresist to UV radiation having a wavelength between 200 nm and 300 nm in vacuum or in an inert atmosphere; c)—breaking the C═C double bonds formed in step b) by reacting the hardened photoresist with ozone (O | 03-25-2010 |
Els Marjaux, Attenrode-Wever BE
| Patent application number | Description | Published |
|---|---|---|
| 20110091446 | SINGLE DOMAIN ANTIBODIES CAPABLE OF MODULATING BACE ACTIVITY - The present invention relates to single domain antibodies with a specificity for BACE1. More specifically, the invention provides single variable domain antibodies derived from camelids which bind to BACE1 and are capable of inhibiting the activity of BACE1. Said antibodies can be used for research and medical applications. Specific applications include the use of BACE1 specific antibodies for the treatment of Alzheimer's disease. | 04-21-2011 |
Els Vanbleu, Ieper BE
| Patent application number | Description | Published |
|---|---|---|
| 20090285784 | DSRNA As Insect Control Agent - The present invention concerns methods for controlling insect infestation via RNAi-mediated gene silencing, whereby the intact insect cell(s) are contacted with a double-stranded RNA from outside the insect cell(s) and whereby the double-stranded RNA is taken up by the intact insect cell(s). In one particular embodiment, the methods of the invention are used to alleviate plants from insect pests. Alternatively, the methods are used for treating and/or preventing insect infestation on a substrate or a subject in need of such treatment and/or prevention. Suitable insect target genes and fragments thereof, dsRNA constructs, recombinant constructs and compositions are disclosed. | 11-19-2009 |
| 20090298787 | Dsrna as Insect Control Agent - The present invention relates to methods for controlling pest infestation using double standard RNA molecules. The invention provides methods for making transgenic plants that express the double stranded RNA molecules, as well as pesticidal agents and commodity products produced by the inventive plants. | 12-03-2009 |
Els Van Bleu, Leper BE
| Patent application number | Description | Published |
|---|---|---|
| 20090306189 | Methods for Controlling Pests Using Rnai - The present invention relates to methods for controlling pest infestation using double stranded RNA molecules. The invention provides methods for producing transgenic cells expressing the double stranded RNA molecules, as well as compositions and commodity products containing or treated with such molecules. | 12-10-2009 |
Els Verhoeyen, Lyon FR
| Patent application number | Description | Published |
|---|---|---|
| 20100247497 | VECTOR PARTICLES FOR TARGETNG CD34+ CELLS - The present invention relates to a vector particle for transferring biological material into cells, wherein said vector particle comprises at least: —a first protein which comprises the transmembrane and extracellular domains of the feline endogenous RD114 virus envelope glycoprotein, and —a second protein which comprises a ligand of the c-Kit receptor. | 09-30-2010 |