Ellman
Bob Ellman, Hugo, MN US
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20110003237 | SLIDEABLE CYLINDRICAL VALVE FOR FUEL CELL - A power generator including one or more fuel cells, a fuel chamber enclosing a hydrogen generating fuel, and one or more slideable cylindrical valves in contact with the fuel chamber. The one or more valves include an inner cylindrical component with first perforations, and a slideable cylindrical component with second perforations and having a plurality of separated flexible sections. The valves are useful in controlling the flow of hydrogen into the anode portion of the fuel cell. | 01-06-2011 |
Brett Ellman, San Diego, CA US
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20120012250 | METHODS OF FORMING AND USING A SOLID-PHASE SUPPORT - Disclosed herein are methods of method of making a substrate for performing a chemical synthesis reaction. | 01-19-2012 |
Herman Ellman, Boonton Township, NJ US
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20150258117 | LOW-DOSE ESTRADIOL CREAM - A low-dose estradiol cream for vaginal administration that is safe and clinically effective to treat symptoms of menopause and a kit comprising the low-dose estradiol cream and an applicator are provided. A method of treatment of the symptoms of vulvar and/or vaginal atrophy associated with menopause, that includes the step of vaginally administering the low-dose estradiol cream to a woman in need thereof is also provided. | 09-17-2015 |
Jan Ellman, Karlsruhe DE
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20100327756 | Arrangement for controlling light emitting diodes - In a circuit arrangement for controlling light emitting diodes (LEDs), which are combined in an indicating table, including a voltage supply, at least one driver which is connected to the voltage supply and has current outputs by way of which current can be supplied to the LEDs as well as at least one control input via which the current being supplied to the LEDs is controllable, a control element is provided by which the number of the LEDs to which current has to be supplied at the same time can be determined and a signal indicative of the number determined can be supplied to the control input of the driver for assisting in controlling the power supply to the LEDs. | 12-30-2010 |
Jonathan Ellman, Herzliya IL
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20130005331 | INTEGRATED NETWORK BASED E-COMMERCE AND ANALYSIS SYSTEMS AND METHODS - Systems and method are provided for forming an integrated communication network. The network includes a plurality of locally distributed integrated communications modules (ICMs) which are placed at predetermined positions. The ICMs monitor a plurality of roaming communication devices that communicate using both the cellular communication network and the internet. Further, the integrated communication network forms a private data base on the roaming sender communication device to allow data communication with a specifically identified roaming communication device. | 01-03-2013 |
Jonathan A. Ellman, Berkeley, CA US
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20110263650 | Tubulysin D Analogues - The present invention provides novel tubulysin analogues, methods of making and methods of using such analogues and conjugates thereof. The essential features for the potent cytotoxicity of tubulysin D have been established for the first time by the synthesis and evaluation of a series of analogues. By identifying functionality that surprisingly is not necessary for activity, highly potent cell-growth inhibitors have been developed that are smaller and considerably more stable than tubulysin D. | 10-27-2011 |
Jonathan A. Ellman, Oakland, CA US
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20090287004 | Method of Converting a Polyol to an Olefin - A method of preparing an olefin comprising: reacting a polyol in the presence of a carboxylic acid, such that an olefin is produced by the deoxygenation of the polyol. The reacting step can comprise (a) providing a composition comprising the polyol, (b) heating the composition, and (c) introducing the carboxylic acid to the composition wherein the introducing step occurs prior to, at the same time as, or subsequent to the heating step. In one embodiment, the polyol is glycerol, the carboxylic acid is formic acid, and the olefin is allyl alcohol, which is produced at a yield of about 80% or greater. | 11-19-2009 |
20100048412 | DETECTION OF PROTEASE AND PROTEASE ACTIVITY USING A SINGLE NANOSCRESCENT SERS PROBE - This invention pertains to the in vitro detection of proteases using a single peptide-conjugate nanocrescent surface enhanced Raman scattering (SERS) probes with at least nanomolar sensitivity. The probe enables detection of proteolytic activity in extremely small volume and at low concentration. In certain embodiments the probes comprise an indicator for the detection of an active protease, where the indicator comprises a nanocrescent attached to a peptide, where said peptide comprises a recognition site for the protease and a Raman tag attached to the peptide. | 02-25-2010 |
20110021568 | TUBULYSIN D ANALOGUES - The present invention provides novel tubulysin analogues, methods of making and methods of using such analogues and conjugates thereof. The compounds of the invention are highly potent cell-growth inhibitors have been developed that are smaller and considerably more stable than tubulysin D. | 01-27-2011 |
20110046018 | SERS-BASED, SINGLE STEP, REAL-TIME DETECTION OF PROTEIN KINASE AND/OR PHOSPHATASE ACTIVITY - This invention provides novel compositions and methods for the detection, and/or quantification, of the presence and/or activity of one or more kinases and/or phosphatases. In certain embodiments this invention a device for the detection of kinase and/or phosphatase activity where the device comprises a Raman active surface comprising features that enhance Raman scattering having attached thereto a plurality of kinase and/or phosphatase substrate molecules. | 02-24-2011 |
20110058164 | Time resolved single-step protease activity quantification using nanoplasmonic resonator (NPR) sensor - A nanoplasmonic resonator (NPR) comprising a metallic nanodisk with alternating shielding layer(s), having a tagged biomolecule conjugated or tethered to the surface of the nanoplasmonic resonator for highly sensitive measurement of enzymatic activity. NPRs enhance Raman signals in a highly reproducible manner, enabling fast detection of protease and enzyme activity, such as Prostate Specific Antigen (paPSA), in real-time, at picomolar sensitivity levels. Experiments on extracellular fluid (ECF) from paPSA-positive cells demonstrate specific detection in a complex bio-fluid background in real-time single-step detection in very small sample volumes. | 03-10-2011 |
20110230527 | CASPASE INHIBITORS AND USES THEREOF - This invention provides novel caspase inhibitors useful for prophylaxis or treatment of a number of pathologies, including, for example, Huntington's disease. In certain embodiments the inhibitors include inhibitors of casepase-3 and/or casepase-6. | 09-22-2011 |
Jonathan A. Ellman, Guilford, CT US
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20140011705 | DETECTION OF PROTEASE AND PROTEASE ACTIVITY USING A SINGLE NANOCRESCENT SERS PROBE - This invention pertains to the in vitro detection of proteases using a single peptide-conjugate nanocrescent surface enhanced Raman scattering (SERS) probes with at least nanomolar sensitivity. The probe enables detection of proteolytic activity in extremely small volume and at low concentration. In certain embodiments the probes comprise an indicator for the detection of an active protease, where the indicator comprises a nanocrescent attached to a peptide, where said peptide comprises a recognition site for the protease and a Raman tag attached to the peptide. | 01-09-2014 |
20140011847 | CASPASE INHIBITORS AND USES THEREOF - This invention provides novel caspase inhibitors useful for prophylaxis or treatment of a number of pathologies, including, for example, Huntington's disease. In certain embodiments the inhibitors include inhibitors of casepase-3 and/or casepase-6. | 01-09-2014 |
20150276610 | REAL-TIME, SINGLE-STEP BIOASSAY USING NANOPLASMONIC RESONATOR WITH ULTRA-HIGH SENSITIVITY - A nanoplasmonic resonator (NPR) comprising a metallic nanodisk with alternating shielding layer(s), having a tagged biomolecule conjugated or tethered to the surface of the nanoplasmonic resonator for highly sensitive measurement of enzymatic activity. NPRs enhance Raman signals in a highly reproducible manner, enabling fast detection of protease and enzyme activity, such as Prostate Specific Antigen (paPSA), in real-time, at picomolar sensitivity levels. Experiments on extracellular fluid (ECF) from paPSA-positive cells demonstrate specific detection in a complex bio-fluid background in real-time single-step detection in very small sample volumes. | 10-01-2015 |
Lance Ellman, Houston, TX US
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20150289667 | Heating and Cooling Sleeping System - A sleeping system is described in which comfort systems for a foam mattress assembly are mounted in a foundation assembly supporting the mattress assembly. The comfort systems include an air heating and cooling system, a firmness system and an elevation system. The foam mattress assembly includes a flexible encasement dish into which one or more foam layers are disposed. Blowers for the air system are mounted adjacent the foundation assembly top in direct fluid communication with apertures in the top, minimizing the air flow path from the blower exhaust to the mattress top to reduce air pressure loss and diminishment of the heated or cooled air. | 10-15-2015 |
Ori Ellman, Tel Aviv IL
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20120272629 | ANTI-POLLUTION, ANTI-BACTERIAL, WATER RESISTANT BABY COVER - A cover of a means for holding children and/or babies, the holding means having at least one opening, wherein the cover includes: (a) means for releasable fastening to the holding means, wherein attachment of the cover to the holding means enables the cover to match its form to openings of the holding means, (b) a layer configured to at least partially filter air introduced via the openings into the holding means, the layer including at least one layer including non-woven material, and (c) at least one window, whereby the child in the holding means is capable of viewing outside the holding means. The windows include a layer impermeable to at least one of the group including dust, air pollutants, viruses, (Rubber) bacteria, UV radiation, liquids and insects. | 11-01-2012 |
Peter Ellman, Carlsbad, CA US
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20130299494 | GARBAGE CONTAINER WITH DETACHABLE MANUAL COMPACTION DEVICE - A self-contained garbage or trash container system with an integrated removable, manual compaction device designed primarily for home or industrial use. The system includes an outer receptacle with attached hinged lid; an internal receptacle; a compaction device; and an attachment mechanism integrated into the lid and/or the compaction device as part of the system to house compaction device. | 11-14-2013 |
Roger Ellman, Santa Rosa, CA US
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20090214884 | Gravitation deflecting mechanisms - This disclosure presents and claims means for the modification of local gravitation by reducing its strength, speed of propagation, and/or its direction of action and presents and claims various uses of those means. The new technology involved is the recognition that light and gravitation flow in the same medium; that the observed effects of gravitational lensing and light diffraction demonstrate the gravitational field of atoms deflecting the flow of that common light/gravitation medium; that a suitable arrangement of atoms thus could produce a desired deflection of gravitation; and that the atomic structure of a cubic crystal [for example Silicon] is suitable for that application. | 08-27-2009 |
20130062887 | Gravito-electric power generation - This disclosure presents and claims means for the modification of local gravitation by modifying its direction of action and presents and claims various uses of those means. The new technology involved is the recognition that light and gravitation flow in the same common medium; that the observed effects of gravitational lensing and light diffraction demonstrate the gravitational field of atoms deflecting the flow of that common medium of light and gravitation; that a suitable arrangement of atoms consequently could produce a desired deflection of gravitation; and that the atomic structure of a cubic crystal [for example Silicon] is suitable for that application. | 03-14-2013 |
Roger Paddock Ellman, Santa Rosa, CA US
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20140367201 | Gravitation deflection anti-gravitational applications - This disclosure presents and claims means for the modification of local gravitation by modifying its direction of action and presents and claims various uses of those means. The new technology involved is the recognition that light and gravitation flow in the same common medium; that the observed effects of gravitational lensing and light diffraction demonstrate the gravitational field of atoms deflecting the flow of that common medium of light and gravitation; that a suitable arrangement of atoms consequently could produce a desired deflection of gravitation; and that the atomic structure of a cubic crystal [for example Silicon] is suitable for that application. | 12-18-2014 |