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Ellis, MA
Andrew B. Ellis, Medford, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20120124372 | Protecting Websites and Website Users By Obscuring URLs - Websites and website users are subject to an increasing array of online threats and attacks. Disclosed herein are, among other things, approaches for protecting websites and website users from online threats. For example, a content server, such as a proxying content delivery network (CDN) server that is delivering content on behalf of an origin server, can modify URLs as they pass through the content server to obscured values that are given to the end-user client browser. The end-user browser can use the obscured URL to obtain content from the content server, but the URL may be valid only for a limited time, and may be invalid for obtaining content from the origin. Hence, information is hidden from the client, making attacks against the website more difficult and frustrating client-end malware that leverages knowledge of browsed URLs. | 05-17-2012 |
Daniel B. Ellis, Holliston, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100145395 | Tissue Repair Assembly - The present disclosure relates to a tissue repair assembly. The assembly includes an interference device and a fixation device coupled to the interference device, wherein the fixation device includes a coupling portion and a capturing portion. Other assemblies and methods are also disclosed. | 06-10-2010 |
| 20120109132 | Device And Method For Use During Ligament Reconstruction - The present disclosure relates to a device for use during ligament reconstruction surgery. The device includes a handle and a shaft coupled to the handle, the handle including a first channel for housing of an insert, a second channel, a third channel for housing of the shaft, a first window, a second window, and a groove. A method for use during ligament reconstruction surgery is also disclosed. | 05-03-2012 |
Debra Ellis, Lowell, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090156537 | COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING ASTHMA OR OTHER ALLERGIC OR INFLAMMATORY DISEASES - The present invention provides compositions and methods useful for detecting or treating asthma or other allergic or inflammatory diseases. In one aspect, the methods of the present invention include inhibiting the activity or expression of a component of an arginine metabolic pathway in tissues affected by asthma or other allergic or inflammatory diseases. In many embodiments, the component being inhibited is a cationic amino acid transporter, an arginase, or a component downstream of the arginase. In many other embodiments, the activity or expression of the component is inhibited by an agent that binds to the component. In still many other embodiments, the activity or expression of the component is inhibited by an agent that binds a polynucleotide encoding the component. | 06-18-2009 |
Edward Ellis, Lynnfield, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100233241 | OPHTHALMIC DRUG DELIVERY SYSTEM AND APPLICATIONS - An ocular device for insertion into an eye is provided and includes a body having an anterior surface and a posterior surface for placement on one of superior sclera and inferior sclera of the eye. The posterior surface is defined by a base curve that is substantially identical to a radius of curvature of the one of the superior sclera and inferior sclera of the eye. In one embodiment, the ocular device serves as an ocular drug delivery system and contains an active pharmaceutical agent, a lubricant, etc. In a second embodiment the ocular device can be constructed in such a manner to treat a wide variety of ocular conditions and diseases. | 09-16-2010 |
| 20120109082 | DEVICES FOR DELIVERING AT LEAST ONE ACTIVE AGENT TO TISSUE - A device for delivering an active agent to target tissue at a site that includes a bodily fluid includes a body having a first exterior surface including a first section having a local, discrete recessed area formed in the body for holding the active agent. The body includes a surface flow feature in the form of a canal that is formed in the body and is recessed relative to the exterior surface. The surface flow feature interfaces with the first section and the local recessed area and is configured so as to guide or modify flow of the bodily fluid relative to the body such that fluid communication is provided between the bodily fluid and the local recessed area. The local recessed area is recessed relative to at least a portion of the canal. | 05-03-2012 |
Edward J. Ellis, Andover, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100178315 | POLYMERIC SYSTEMS FOR CONTROLLED DRUG THERAPY - Polymeric compositions containing a high percentage of bound alkyl ether segments provide matrices and membranes for the controlled release of drugs and medicinal agents. The polymeric compositions are prepared by the polymerization of ethylenically unsaturated alkyl ether containing monomers. Copolymers of ethylenically unsaturated alkyl ether containing monomers with co-monomers are also disclosed. The drug loaded polymeric compositions of this invention find particular utility in the construction of controlled release devices. | 07-15-2010 |
Edward J. Ellis, Lynnfield, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20120109054 | DEVICES WITH AN ERODIBLE SURFACE FOR DELIVERING AT LEAST ONE ACTIVE AGENT TO TISSUE OVER A PROLONGED PERIOD OF TIME - A device is disclosed for delivering an active agent to target tissue at a site that includes a bodily fluid. The device includes a body that has an erodible member that releases the active agent over a prescribed period of time. | 05-03-2012 |
James L. Ellis, Boxford, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090018091 | Nitric Oxide Enhancing Antimicrobial Compounds, Compositions and Methods of Use - The invention describes compositions and kits comprising at least one nitric oxide enhancing group antimicrobial compound, or pharmaceutically acceptable salts thereof, and novel compositions comprising at least one nitric oxide enhancing antimicrobial compound, and, optionally, at least one nitric oxide enhancing compound and/or at least one therapeutic agent. The invention also provides methods for (a) treating bacterial infections; (b) treating viral infections; (c) treating fungal infections; and (d) treating lesions. The antimicrobial compounds of the invention are preferably tobramycin, aztreonam, ciprofloxacin and doripenam. The nitric oxide enhancing antimicrobial compounds are substituted with at least one heterocyclic nitric oxide donor group and/or at least one nitroxide group. The nitric oxide enhancing groups are nitroxides and/or heterocyclic nitric oxide donors. The heterocyclic nitric oxide donors are furoxans, sydnonimines, oxatriazole-5-ones and/or oxatriazole-5-imines. In one embodiment the methods of the invention are for the treatment of bacterial infections associated with pulmonary diseases such as cystic fibrosis and for treating | 01-15-2009 |
| 20090042819 | Organic nitric oxide donor salts of antimicrobial compounds, compositions and methods of use - The invention describes novel organic nitric oxide donor salts of a antimicrobial compounds, and novel compositions and kits comprising at least one organic nitric oxide donor salt of an antimicrobial compound, and, optionally, at least one nitric oxide enhancing compound and/or at least one therapeutic agent. The invention also provides methods for (a) treating bacterial infections; (b) treating viral infections; (c) treating fungal infections; and (d) treating lesions. In one embodiment the antimicrobial compounds of the invention are aztreonam, ciprofloxacin, doripenam, duramycin and tobramycin. The organic nitric oxide donors that form salts are preferably organic nitrates, organic nitrites, nitrosothiols, thionitrites and heterocyclic nitric oxide donors. The heterocyclic nitric oxide donors are preferably furoxans, sydnonimines, oxatriazole-5-ones and/or oxatriazole-5-imines. The methods of the invention are preferably for the treatment of bacterial infections associated with pulmonary diseases such as cystic fibrosis and for treating | 02-12-2009 |
| 20090131342 | Nitrosated and/or nitrosylated compounds, compositions and methods of use - The invention describes novel nitrosated and/or nitrosylated compounds of the invention and pharmaceutically acceptable salts thereof, and novel compositions comprising at least one nitrosated and/or nitrosylated compound of the invention, and, optionally, at least one nitric oxide donor and/or at least one therapeutic agent. The invention also provides novel compositions comprising at least one compound of the invention, and at least one nitric oxide donor and/or at least one therapeutic agent. The invention also provides novel kits comprising at least one compound of the invention, that is optionally nitrosated and/or nitrosylated, and, optionally, at least one nitric oxide donor and/or at least one therapeutic agent. The invention also provides methods for (a) treating bacterial infections; (b) treating viral infections; (c) treating fungal infections; and (d) treating lesions. The nitrosated and/or nitrosylated compounds of the invention are preferably nitrosated and/or nitrosylated antimicrobial compounds, nitrosated and/or nitrosylated adenosine antagonists, nitrosated and/or nitrosylated LTB4 antagonists, nitrosated and/or nitrosylated mucoregulators and nitrosated and/or nitrosylated purine agonists. The methods of the invention are preferably for the treatment of bacterial infections associated with pulmonary diseases such as cystic fibrosis. | 05-21-2009 |
James P. Ellis, Waltham, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20120040124 | REINFORCED WALKWAY SYSTEM - Disclosed is a reinforced walkway system having an embossed walkway performance layer made of a polymer composite and a composite reinforcement layer thermally bonded thereto. The reinforcement layer includes a high temperature reinforcing composite which is thermally applied to the underside of the performance layer to prevent delamination and maintain the dimensional stability of the embossed performance layer at high temperatures. In one embodiment, the walkway performance layer may comprise any of polyolefin (TPO), Polyvinylchloride (PVC), and Elvaloy/Polyvinylchloride optionally mixed with other additives such as UV protection or mineral fillers. A method of forming a reinforced walkway system includes substantially simultaneously thermally bonding the performance layer to the composite reinforcement layer and embossing the performance layer. | 02-16-2012 |
Jeanne Y. Ellis, Andover, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100178315 | POLYMERIC SYSTEMS FOR CONTROLLED DRUG THERAPY - Polymeric compositions containing a high percentage of bound alkyl ether segments provide matrices and membranes for the controlled release of drugs and medicinal agents. The polymeric compositions are prepared by the polymerization of ethylenically unsaturated alkyl ether containing monomers. Copolymers of ethylenically unsaturated alkyl ether containing monomers with co-monomers are also disclosed. The drug loaded polymeric compositions of this invention find particular utility in the construction of controlled release devices. | 07-15-2010 |
Jeanne Y. Ellis, Lynnfield, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100233241 | OPHTHALMIC DRUG DELIVERY SYSTEM AND APPLICATIONS - An ocular device for insertion into an eye is provided and includes a body having an anterior surface and a posterior surface for placement on one of superior sclera and inferior sclera of the eye. The posterior surface is defined by a base curve that is substantially identical to a radius of curvature of the one of the superior sclera and inferior sclera of the eye. In one embodiment, the ocular device serves as an ocular drug delivery system and contains an active pharmaceutical agent, a lubricant, etc. In a second embodiment the ocular device can be constructed in such a manner to treat a wide variety of ocular conditions and diseases. | 09-16-2010 |
John Michael Ellis, Needham, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110245205 | AMINOPYRIMIDINES AS SYK INHIBITORS - The present invention provides novel pyrimidine amines of formula (I) which are potent inhibitors of spleen tyrosine kinase, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD and rheumatoid arthritis. | 10-06-2011 |
Lawrence A. Ellis, Wakefield, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20080212264 | SYSTEM AND METHOD FOR DISTRIBUTION OF ELECTRICAL POWER - An electrical power distribution system that includes a circuit splitting mechanism configured to receive electrical power and to output a plurality of separate electrical circuits having a modular connector that has a plurality of contacts, each contact connected to one circuit of the plurality of separate electrical circuits. Each contact of the modular connector is selected to conduct at least one of an elevated current and an elevated voltage. Each connector is connected to a plurality of wires that extend through a housing that routes and connects the wires to one or more additional connectors positioned at a distal location, typically via a distribution housing having the additional connectors mounted on the housing, for connecting/routing the power from the separate circuits to one or more mechanisms positioned at a distal location that use the electrical power. | 09-04-2008 |
| 20090181565 | SYSTEM AND METHOD FOR DISTRIBUTION OF ELECTRICAL POWER - An electrical power distribution system comprising: | 07-16-2009 |
| 20100175919 | SYSTEM AND METHOD FOR DISTRIBUTION OF ELECTRICAL POWER - An apparatus for delivering electrical power to an electrically powered device, the apparatus comprising: | 07-15-2010 |
| 20100175920 | SYSTEM AND METHOD FOR DISTRIBUTION OF ELECTRICAL POWER - An electrical power distribution and mounting system, the system comprising: | 07-15-2010 |
| 20110284710 | MULTI-LAYER IMPACT RESISTANT BUMPER - An impact absorbing and resistant bumper comprising: | 11-24-2011 |
Randall P. Ellis, Newton, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110161094 | System and method for health care costs and outcomes modeling using dosage and routing pharmacy information - A system for health care costs and outcomes modeling for members of a defined subject population using dosage and routing information is disclosed. | 06-30-2011 |
Timothy Peter Ellis, Boxborough, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100112639 | ENHANCED PRODUCTION AND PURIFICATION OF A NATURAL HIGH INTENSITY SWEETENER - Recombinant | 05-06-2010 |
Warren Ellis, Worcester, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20120088022 | INFANT FORMULA DEVICE - An apparatus is provided for accurately dispensing a powder such as powdered infant formula into a container, and pasteurizing and reconstituting the powdered formula while completely mixing the formula in the container. The apparatus includes a hopper assembly for storing powder, a dosing assembly for measuring and dispensing powder from a receptacle into the container, a dilution assembly and a mixing assembly for obtaining accurately and completely mixed formula from the dispensed powder. The hopper is shaped to promote powder bridging, and the resulting powder bridge is used in combination with the dosing assembly to provide a predetermined amount of powder using a single mechanical valve that is isolated from the powder. The mixing assembly mixes the contents of the container while holding the bottle at a fixed angle relative to the vertical. A method of providing pasteurized infant formula from an infant formula powder is also disclosed. | 04-12-2012 |