Ellen S.
Ellen S. Gawalt, Pittsburgh, PA US
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20120087950 | FUNCTIONALIZED CALCIUM PHOSPHATE ARTIFICIAL BONE AND JOINT COMPOSITIONS AND METHODS OF USE AND MANUFACTURE - The present invention provides a functionalized composition and resulting functionalized body or prosthesis for in vitro and in vivo use comprising at least one calcium phosphate containing phase that is functionalized with a linker group comprising at least one of an organic acid molecule, a phosphonic acid, an amine, N,N-dicyclohexylcarbodiimide, and 3-maleimidopropionic acid N-hydroxysuccinimide ester, and combinations thereof, and one or more of a chemical and/or a biologically active moieties, wherein the linker group provides for a reactive location for the attachment of the chemical or biologically active moiety, or both, to the calcium phosphate containing phase, and optionally including an unmodified and/or modified calcium aluminate containing phase. The functionalized compositions have a pliable physical property when mixed with water and adhere to natural bone and subsequently harden at ambient temperatures. Methods of manufacturing a functionalized artificial prosthesis that may be used as artificial bones, joints, in-vitro support structures, and in-vivo support structures for cells, tissues, organs, and nerve growth and regeneration are disclosed. Methods of repairing a bone, vertebrae, or tissue structures using the functionalized compositions are provided. | 04-12-2012 |
20120114935 | DEVICES WITH MULTIPLE SURFACE FUNCTIONALITY - Phosphorus-based coatings having a plurality of phosphate moieties, a plurality of phosphonate moieties, or both, covalently bonded to an oxide surface of an implantable substrate exhibiting one or more of the following characteristics: (a) the surface phosphorus-containing group density of the coated regions of the substrate is at least about 0.1 nmol/cm | 05-10-2012 |
20120121661 | DEVICES WITH MULTIPLE SURFACE FUNCTIONALITY - Phosphorus-based coatings having a plurality of phosphate moieties, a plurality of phosphonate moieties, or both, covalently bonded to an oxide surface of an implantable substrate exhibiting one or more of the following characteristics: (a) the surface phosphorus-containing group density of the coated regions of the substrate is at least about 0.1 nmol/cm | 05-17-2012 |
20130029960 | ENHANCED BONE HEALING - The combined use—whether by adsorption or covalent linkage—of Melatonin adjacent any bone implant or graft, preferably any calcium- and oxide-containing artificial bone graft material, and more preferably a calcium aluminate composition. Alternatively, the bone graft or implant material may be used as a scaffold for tissue engineering. | 01-31-2013 |
Ellen S. Gawalt, Chicago, IL US
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20080206443 | ENHANCED BONDING LAYERS ON TITANIUM MATERIALS - The present invention provides a dense-coverage, adherent phosphorous-based coating on the native oxide surface of a material. Disclosed phosphorous-based coatings include phosphate and organo-phosphonate coatings. The present invention also provides further derivatization of the phosphorous-based coatings to yield dense surface coverage of chemically reactive coatings and osteoblast adhesion-promoting and proliferation-promoting coatings on the native oxide surface of a titanium material. | 08-28-2008 |
Ellen S. Pfafflin, Allen Park, MI US
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20110146736 | Walker - A walker has a wheel rotatably mounted to the lower end of each of a pair of front legs, each wheel having a series of end to end smaller diameter rollers mounted about the axis of wheels | 06-23-2011 |
Ellen S. Pizer, Bellevue, WA US
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20080253963 | Tumor markers in ovarian cancer - The present invention features methods of diagnosing and prognosticating ovarian tumors by detecting increased expression of an ovarian tumor marker gene in a subject or in a sample from a subject. Also featured are kits for the aforementioned diagnostic and prognostic methods. In addition, the invention features methods of treating and preventing ovarian tumors, and methods of inhibiting the growth or metastasis of ovarian tumors, by modulating the production or activity of an ovarian tumor marker polypeptide. Further featured are methods of inhibiting the growth or metastasis of an ovarian tumor by contacting an ovarian tumor cell with an antibody that specifically binds an ovarian tumor marker polypeptide. | 10-16-2008 |
20100183507 | TUMOR MARKERS IN OVARIAN CANCER - The present invention features methods of diagnosing and prognosticating ovarian tumors by detecting increased expression of an ovarian tumor marker gene in a subject or in a sample from a subject. Also featured are kits for the aforementioned diagnostic and prognostic methods. In addition, the invention features methods of treating and preventing ovarian tumors, and methods of inhibiting the growth or metastasis of ovarian tumors, by modulating the production or activity of an ovarian tumor marker polypeptide. Further featured are methods of inhibiting the growth or metastasis of an ovarian tumor by contacting an ovarian tumor cell with an antibody that specifically binds an ovarian tumor marker polypeptide. | 07-22-2010 |
Ellen S. Taurins, Flushing, NY US
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20100187384 | SUPPORT DEVICE - A support device for supporting at least one predetermined foldable member includes a pair of bracket members for mounting on a predetermined vertical structure a predetermined distance apart, a securing mechanism operably connected to each bracket member and engageable with such predetermined vertical structure for securing each of such bracket members to such predetermined vertical structure, and a support rod manufactured from a first predetermined material and having a first predetermined size and a first predetermined shape and including a first end and a second end, such support rod for supporting such at least one predetermined foldable member releasably thereon and being releasably supportable in a substantially horizontal position by such bracket members. | 07-29-2010 |
Ellen S. Tormey, Princeton Junction, NJ US
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20100118510 | HIGH COLOR RENDERING INDEX WHITE LED LIGHT SYSTEM USING MULTI-WAVELENGTH PUMP SOURCES AND MIXED PHOSPHORS - The present invention relates to an LED lighting system producing light having improved Color Rendering Index (CRI). The system includes a plurality of LEDs wherein the LEDs have at least a first and second characteristic wavelength, and a mixed phosphor layer overlying at least one of a portion of the plurality of LEDs, the phosphor layer absorbing at least a portion of the LED-emitted light and producing phosphor-emitted light, wherein the phosphors includes a third characteristic wavelength and a fourth characteristic wavelength, wherein the third characteristic wavelength and fourth characteristic wavelength are not the same. | 05-13-2010 |
20140328039 | SYSTEMS AND METHODS FOR VOID REDUCTION IN A SOLDER JOINT - In accordance with one or more aspects, a method of reducing void formation in a solder joint may comprise applying a solder paste deposit to a substrate, placing a solder preform in the solder paste deposit, disposing a device on the solder preform and the solder paste deposit, and processing the solder paste deposit and the solder preform to form the solder joint between the device and the substrate. In some aspects, the substrate is a printed circuit board and the device is an integrated circuit package. | 11-06-2014 |
20150078810 | SOLDER PREFORMS AND SOLDER ALLOY ASSEMBLY METHODS - A method of assembling components, such as electronic components, onto a substrate, such as an electronic substrate, includes applying solder paste to an electronic substrate to form a solder paste deposit, placing a low temperature preform in the solder paste deposit, processing the electronic substrate at a reflow temperature of the solder paste to create a low temperature solder joint, and processing the low temperature solder joint at a reflow temperature that is lower than the reflow temperature of the solder paste. Other methods of assembling components and solder joint compositions are further disclosed. | 03-19-2015 |
Ellen S. Vitetta, Dallas, TX US
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20120123097 | RICIN A CHAIN MUTANTS LACKING ENZYMATIC ACTIVITY AS VACCINES TO PROTECT AGAINST AEROSOLIZED RICIN - The present invention provides methods to produce toxoid vaccines, such as ricin A chain vaccines, with reduced ability to promote vascular leak syndrome (VLS) and catalytic toxicity associated with various proteinaceous toxins, such as ribosome inactivating proteins. The invention also provides toxoids which have been mutated to lack amino acid sequences which induce VLS and toxic catalytic activity. | 05-17-2012 |
Ellen S. Yetzer, San Francisco, CA US
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20100221217 | THERAPEUTIC COMPOSITION - Embodiments disclosed in the present application relate to a composition that can include a hepatitis C viral polymerase inhibitor, or pharmaceutically acceptable salt or prodrug thereof and a hepatitis C viral protease inhibitor, or pharmaceutically acceptable salt or prodrug thereof. Additional embodiments disclosed relate to methods for treating a disease condition such as a hepatitis C virus infection, liver fibrosis and/or impaired liver function with a hepatitis C viral polymerase inhibitor, or pharmaceutically acceptable salt or prodrug thereof and a hepatitis C viral protease inhibitor, or pharmaceutically acceptable salt or prodrug thereof. | 09-02-2010 |
20120128628 | COMBINATION OF A NUCLEOSIDE POLYMERASE INHIBITOR WITH A MACROCYCLIC PROTEASE INHIBITOR AND USE THEREOF IN THE TREATMENT OF HEPATITIS C, LIVER FIBROSIS AND IMPAIRED LIVER FUNCTION (as amended) - Embodiments disclosed in the present application relate to a composition that can include a hepatitis C viral polymerase inhibitor, or pharmaceutically acceptable salt or prodrug thereof and a hepatitis C viral protease inhibitor, or pharmaceutically acceptable salt or prodrug thereof. Additional embodiments disclosed relate to methods for treating a disease condition such as a hepatitis C virus infection, liver fibrosis and/or impaired liver function with a hepatitis C viral polymerase inhibitor, or pharmaceutically acceptable salt or prodrug thereof and a hepatitis C viral protease inhibitor, or pharmaceutically acceptable salt or prodrug thereof. | 05-24-2012 |