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Elia

Elia Beniash, Auburndale, MA US

Patent application numberDescriptionPublished
20090156505SELF-ASSEMBLY AND MINERALIZATION OF PEPTIDE-AMPHIPHILE NANOFIBERS - Peptide-amphiphilic compositions capable of self-assembly into useful nanostructures.06-18-2009
20110008890Self-Assembly of Peptide-Amphiphile Nanofibers Under Physiological Conditions - Peptide amphiphile compounds, compositions and methods for self-assembly or nanofibrous network formation under neutral or physiological conditions.01-13-2011

Patent applications by Elia Beniash, Auburndale, MA US

Elia Beniash, Newton, MA US

Patent application numberDescriptionPublished
20100221224COMPOSITION AND METHOD FOR SELF-ASSEMBLY AND MINERALIZATION OF PEPTIDE-AMPHIPHILES - The present invention is directed to a composition useful for making homogeneously mineralized self assembled peptide-amphiphile nanofibers and nanofiber gels. The composition is generally a solution comprised of a positively or negatively charged peptide-amphiphile and a like signed ion from the mineral. Mixing this solution with a second solution containing a dissolved counter-ion of the mineral and/or a second oppositely charged peptide amphiphile, results in the rapid self assembly of the peptide-amphiphiles into a nanofiber gel and templated mineralization of the ions. Templated mineralization of the initially dissolved mineral cations and anions in the mixture occurs with preferential orientation of the mineral crystals along the fiber surfaces within the nanofiber gel. One advantage of the present invention is that it results in homogenous growth of the mineral throughout the nanofiber gel. Another advantage of the present invention is that the nanofiber gel formation and mineralization reactions occur in a single mixing step and under substantially neutral or physiological pH conditions. These homogeneous nanostructured composite materials are useful for medical applications especially the regeneration of damaged bone in mammals. This invention is directed to the synthesis of peptide-amphiphiles with more than one amphiphilic moment and to supramolecular compositions comprised of such multi-dimensional peptide-amphiphiles. Supramolecular compositions can be formed by self assembly of multi-dimensional peptide-amphiphiles by mixing them with a solution comprising a monovalent cation.09-02-2010

Elia Fishbein, Jerusalem IL

Patent application numberDescriptionPublished
20120021035Nanoparticles containing plymeric nucleic acid homologs, pharmaceutical composition and articles of manufacture containing same and methods of use thereof - A nanoparticle capable of delivery of an encapsulated molecule into a living cell. The nanoparticle includes an encapsulation media and an isolated nucleic acid homolog sequence. The encapsulation media is primarily polymeric. The nanoparticles release the encapsulated molecule over an extended period of time. Further disclosed are pharmaceutical compositions and articles of manufacture including nanoparticles and methods of preparing and using the nanoparticles.01-26-2012

Elia Zois, Palm Beach, FL US

Patent application numberDescriptionPublished
20090264173VIDEO GAME AND METHOD OF PLAY - Systems and methods provide for a player to determine the feelings and state of mind of a virtual patient via the types of defensive answers, or defenses, the patient provides to the player. On the basis of the defenses given by the patient, the player further challenges the patient by asking additional focus questions and determines which additional defenses are provided by the patient. Points are granted to the player for the successful determination of the player's true feelings and/or state of mind.10-22-2009