Patent application number | Description | Published |
20100166697 | COMBINATION THERAPY USING TNF AND ALFA-GALACTOSYL CERAMIDE - The invention relates to the treatment of cancer. More specifically the invention shows that the anti-cancer activity in mammals can be augmented by administering to the mammalian host a combination of a synergistically effective amount of TNF and alfa-galactosylceramide. | 07-01-2010 |
20100330036 | MARKERS OF MATRIX GENE EXPRESSION AND CELLULAR DIFFERENTIATION IN CHONDROCYTES - The invention relates generally to the field of tissue engineering. More particularly, the present invention relates to methods for identifying a population of cells suitable for the repair of connective tissue, including cartilage. The invention further provides methods and compositions related to the generation of a population of cells suitable for the repair of cartilage, in particular in the repair of cartilage degeneration associated with osteoarthritis. Methods of using said cells thus identified or thus generated, in methods to extend the period of cell manipulation, i.e. to increase the yield of cells suitable in the aforementioned methods, are also provided by the present invention. | 12-30-2010 |
20110172182 | Carboxyethylated Cyclodextrin Polysulfates Useful As Medicaments - This invention relates to novel β-cyclodextrin polysulfate compounds comprising from one to three 2-carboxyethyl substituents, and at least two sulfates groups per glucopyranose unit, which are useful as active ingredients for the treatment and/or prophylaxis of degenerative joint diseases, osteoarthritis, articular rheumatism, arthrosis or degenerative arthritis, or for the treatment of heparin-induced thrombocytopenia, or for cartilage repair or connective tissue repair. | 07-14-2011 |
20110263948 | SCORING SYSTEM TO MONITOR NATURAL OR DRUG-MODIFIED DISEASE PROGRESSION IN "EROSIVE OSTEOARTHRITIS" OF THE INTERPHALANGEAL FINGER JOINTS - The present invention provides a scoring system to monitor natural or drug-modified disease progression in erosive inter-phalangeal finger joint osteoarthrits and the use of said scoring system to identify and value drugs with anticatabolic and/or repair promoting potential. | 10-27-2011 |
20110300548 | GDF15 AS MOLECULAR TOOL TO MONITOR AND ENHANCE PHENOTYPIC STABILITY OF ARTICULAR CHONDROCYTES - The present invention relates to GDF15 as a molecular marker in in vitro assays determining phenotypic stability of articular chondrocytes and predicting the outcome of chondrocyte transplantation. | 12-08-2011 |
20110300562 | GDF15 AS A DIFFERENTIAL MARKER FOR SPONDYLOARTHROPATHY - In vitro methods for differential diagnosis of spondyloarthropathy are disclosed which involve determining the levels of GDF15 in biological samples. | 12-08-2011 |