Eleonora
Eleonora Amici, East Cowes GB
Patent application number | Description | Published |
---|---|---|
20090149597 | Method of Producing Fine Particles - A method of producing cross-linked polymerisation hardened droplets in a continuous aqueous medium in a microchannel device is provided. At least two aqueous streams are brought together before entering a hydrophobic phase and thus forming droplets. One aqueous phase comprises an acid source and another comprises a metal ion salt. The slow release of metal ions slows down the rate of polymerisation so that it does not interfere with the droplet formation process. | 06-11-2009 |
Eleonora Baldelli, Bologna IT
Patent application number | Description | Published |
---|---|---|
20080242864 | Process for the Semisynthesis of Deserpidine - The present invention relates to an efficient procedure for the synthesis of deserpidine (Ia), starting from reserpic acid lactone (II) via the intermediate 11-O-demethyl reserpic acid lactone (III). | 10-02-2008 |
Eleonora Beljaars, Groningen NL
Patent application number | Description | Published |
---|---|---|
20080267877 | Peptide-based carrier devices for stellate cells - A compound includes a carrier molecule wherein the carrier molecule is linked to a further molecule, wherein the further molecule is at least one cyclic peptide in which the cyclic peptide portion thereof contains at least one sequence encoding a cell receptor recognizing peptide (RRP) and with the proviso that the compound is not a naturally occurring receptor agonist or antagonist. Preferably, the RRP is a receptor specific for Hepatic Stellate Cells (HSC) or a receptor that is up-regulated on HSC during disease. The RFP may be chosen from among a PDGF receptor, a collagen type VI receptor, cytokine receptor(s) such as TGBβ, INFα and interleukinβ. The cyclic portion of the peptide can contain at least one amino acid sequence RGD or KPT. The compounds can be used as an active targeting ingredient for manufacturing a pharmaceutical composition for therapy, prophylaxis or diagnosis of a disease chosen from fibrotic disease, sclerotic disease, and chronic or acute inflammatory processes including glomeruloscherosis, interstitial fibrosis, lung fibrosis, atherosclerosis, rheumatoid arthritis, Crohns disease, colitis ulcerosa, glomerulonephritis and sepsis, and particularly for targeting HSC. Pharmaceutical compositions contain the above-compound(s). | 10-30-2008 |
20130064791 | Interferon Analogs - The invention relates to the field of medicine. Among others, it relates to biologically active analogs of interferons (IFNs) which show less unwanted side-effects and to the therapeutic uses thereof. Provided is an IFN analog, wherein the moiety mediating binding to its natural receptor is at least functionally disrupted and wherein the analog comprises a signaling moiety capable of mediating intracellular IFN activity, said signaling moiety being provided at its N-terminus, optionally via a linker, with at least one targeting domain capable of binding to a cell surface receptor other than the IFN receptor. | 03-14-2013 |
Eleonora Candi, Rome IT
Patent application number | Description | Published |
---|---|---|
20130071370 | INHIBITORS OF MICRO-RNAS FOR USE FOR PREVENTING AND/OR ATTENUATING SKIN AGEING AND/OR FOR HYDRATING SKIN - Method of identifying and using compounds which inhibit the expression or activity of micro-RNAs for preventing and/or attenuating ageing, and/or for hydrating skin. An in vitro method for screening for candidate compounds for preventing and/or attenuating ageing of the skin, and/or for hydrating the skin, includes the following steps: | 03-21-2013 |
20140065250 | INHIBITORS OF MICRO-RNAS FOR USE FOR PREVENTING AND/OR ATTENUATING SKIN AGEING - Identification and use of compounds which inhibit the expression or activity of micro-RNAs for preventing and/or attenuating ageing. An in vitro method for screening for candidate compounds for preventing and/or attenuating ageing of the skin including (a) bringing at least one test compound in contact with a sample of fibroblasts, (b) measuring the expression or the activity of at least one microRNA chosen from miR-134 and miR-152 in said fibroblasts, and (c) selecting the compounds for which an inhibition of at least 20%, preferably at least 30%, preferably at least 40% of the expression or an inhibition of at least 20%, preferably at least 30%, preferably at least 40% of the activity of at least one microRNA is measured in the fibroblasts treated in (a) compared with the untreated fibroblasts. | 03-06-2014 |
Eleonora Dinisman-Zavulunov, Afula IL
Patent application number | Description | Published |
---|---|---|
20090143360 | Oxcarbazepine Formulation - The present invention relates to novel uncoated, color-stable tablet formulations comprising oxcarbazepine, a disintegrant and iron oxide pigments. The oxcarbazepine of the present invention has a particle size of about 14 to about 30 microns with a maximum residue on a 40 micron sieve from about 10% to about 35%. The present invention further provides for a process of preparing the tablet formulations, and a method of treating mammals in need of oxcarbazepine with the novel formulation. | 06-04-2009 |
Eleonora Doucet-Liem, Leiden NL
Patent application number | Description | Published |
---|---|---|
20090169286 | DEVICE FOR APPLYING A SPREADABLE COMPOSITION TO A PART OF THE HUMAN OR ANIMAL BODY - A device for applying a spreadable composition to a part of the human or animal body, wherein the device comprises a container containing the spreadable composition, an applicator for the spreadable composition and means for urging the spreadable composition out of the container and into contact with the applicator, provided with positioning means connected to the container for positioning the applicator in a position in which composition urged out of the container can be brought into contact with the applicator. | 07-02-2009 |
Eleonora Franchi Scarselli, Bologna IT
Patent application number | Description | Published |
---|---|---|
20110319014 | ELECTRONIC CIRCUIT FOR COMMUNICATING THROUGH CAPACITIVE COUPLING - A device and method to compensate for distortions of amplitude that afflict systems for communicating through capacitive coupling. A circuit includes a first transmitter stage, a first receiver stage, and a first coupling capacitor, coupled between the first transmitter stage and the first receiver stage. The first receiver stage includes a calibration amplifier of a variable-gain type coupled between the first coupling capacitor and an output of the electronic circuit. The electronic circuit includes a reference channel formed by: a transmission calibration stage; a reception calibration stage; and a reference capacitor coupled between the transmission calibration stage and the reception calibration stage. The reception calibration stage includes: a reception amplifier of a variable-gain type, having an input coupled to the reference capacitor, and a gain controller, having an input coupled to an output of the reception amplifier and an output coupled to control terminals of the reception and calibration amplifiers. | 12-29-2011 |
20110319015 | METHOD FOR VERIFYING THE ALIGNMENT BETWEEN INTEGRATED ELECTRONIC DEVICES - A method for verifying alignment between first and second integrated devices coupled together using a reference and a coupling capacitor, including: transmitting a reference signal on a transmission electrode of the reference capacitor; receiving a coupling signal on a reception electrode of the reference capacitor; amplifying the coupling signal, generating a reception reference signal; generating a reception control signal as a function of the reception reference signal; transmitting a communication signal on an electrode of the coupling capacitor; receiving a reception signal on an electrode of the coupling capacitor; amplifying the reception signal, generating a first compensated signal; controlling a level of amplification of amplifying the coupling signal and the reception signal as a function of the reception control signal; and detecting a possible misalignment between the first and second devices based on an amplitude of the communication signal and an amplitude of the compensated signal. | 12-29-2011 |
20130001547 | METHOD FOR VERIFYING THE ALIGNMENT BETWEEN INTEGRATED ELECTRONIC DEVICES - A method includes communicatively coupling first and second integrated electronic devices together through a plurality of reference capacitors, transmitting a plurality of transmission reference signals on transmission reference electrodes of the plurality of reference capacitors, receiving coupling signals on reception reference electrodes of the plurality of reference capacitors, amplifying said coupling signals, generating a plurality of reception reference signals, generating a plurality of reception control signals as a function of the plurality of reception reference signals, and detecting a possible misalignment between said first and second integrated electronic devices based on the plurality of reception control signals. | 01-03-2013 |
20130027071 | ACTIVE PROBE CARD FOR ELECTRICAL WAFER SORT OF INTEGRATED CIRCUITS - A testing apparatus includes a tester and a probe card system that includes a probe card connected to the tester, and an active interposer connected to the probe card and wirelessly coupled with a device to be tested. The active interposer includes pads positioned on its free surface facing the device. The pads are positioned with respect to pads of the device so that each pad of the active interposer faces a pad of the device and is separated therefrom by a dielectric. Each pair of facing pads forms an elementary wireless coupling element which allows a wireless transmission between the active interposer and the device. The active interposer also includes an amplifier circuit configured to amplify wireless signals from the device before forwarding them to the tester. The probe card system includes a transmission element able to transmit a power voltage from the tester to the device. | 01-31-2013 |
Eleonora Maldacena, Buenos Aires AR
Patent application number | Description | Published |
---|---|---|
20090264334 | Cleaning compositions - The present invention discloses cleaning compositions comprising a combination of surfactants and viscosity modifying agent including electrolyte, that upon dilution thickens so as to form a gel. The compositions are useful for household cleaning activities such as dishwashing. They provide enhanced and progressive retention of surfactant in carriers, thus avoid excessive product consumption and providing more yield. | 10-22-2009 |
Eleonora Marsich, Trieste IT
Patent application number | Description | Published |
---|---|---|
20090197832 | POLYMER MIXTURES OF ANIONIC AND CATIONIC POLYSACCHARIDES AND USE THEREOF - Described in the present application are compositions comprising mixtures of polyanionic polysaccharides and polycationic polysaccharides consisting of oligosaccharide derivatives of chitosan. In the compositions of the invention said mixtures have proven to be soluble in aqueous environments, despite ionic complexes forming between the acid polysaccharides and chitosan derivatives. Said compositions have also demonstrated significant rheological behaviour with an unexpected increase in viscosity and viscoelasticity, although the polysaccharides used have relatively low average molecular weights. The said solubility and rheological behaviour renders the compositions of the invention particularly advantageous from the biomedical application viewpoint, in particular for viscosupplementation and particularly in the field of articular pathologies and of ophthalmic surgery. | 08-06-2009 |
20090202640 | HYDROGELS OF POLYSACCHARIDE MIXTURES FOR TISSUE ENGINEERING AND AS CARRIERS OF ACTIVE COMPOUNDS - The present invention describes the preparation of hydrogels (or 3D matrices) obtainable from aqueous solutions of mixtures of acid polysaccharides and derivatives of basic polysaccharides, such as oligosaccharide derivatives of chitosan. Said solutions are suitably gelled with either chemical or physical gelling agents with the aim of encapsulating either cells, isolated or in multicellular associations, or pharmacologically active molecules, in solution or suspension, for use in the biomedical and pharmaceutical field. | 08-13-2009 |
20110123589 | THREE-DIMENSIONAL NANOCOMPOSITE MATERIALS CONSISTING OF A POLYSACCHARIDIC MATRIX AND METALLIC NANOPARTICLES, PREPARATION AND USE THEREOF - In the present invention nanocomposite materials in form of three-dimensional structure formed by a polymeric matrix consisting of a polysaccharidic composition of neutral or anionic polysaccharides and a branched cationic polysaccharides, in which metallic nanoparticles are uniformly dispersed and stabilized, are described. Using appropriate techniques of gelification or by means of an appropriate dehydration, the nanocomposite materials are three-dimensional matrices having different shapes in hydrated form as hydrogels, or in non-hydrated form. These nanocomposite materials have a broad-spectrum of strong bactericidal activity, but do not show any cytotoxicity. The particular antibacterial properties associated with metallic particle nano-scale and the presence of biological signals on the polymeric chains along with the lack of cytotoxicity may be exploited in developing new-generation biomaterials provided with antimicrobial properties and for many other applications in biomedical, pharmaceutical and food field. | 05-26-2011 |
20110129536 | NANOCOMPOSITE MATERIALS BASED ON METALLIC NANOPARTICLES STABILIZED WITH BRANCHED POLYSACCHARIDES - The present invention provides nanocomposite systems made of metallic nanoparticles stabilized with branched cationic polysaccharides, in particular alditolic or aldonic mono- and oligo-saccharidic derivatives of chitosan, and their preparation obtainable with aqueous solutions of these polysaccharides in the presence or absence of reducing agents. The peculiar chemical and physical-chemical features of these polysaccharides allow to form metallic nanoparticles homogeneously dispersed in the polysaccharidic matrix and an effective stabilization thereof. The properties associated with the nanometric dimensions and the presence of biological signals on polymeric chains may be exploited in applications with antimicrobial activities and of molecular biosensors. | 06-02-2011 |
Eleonora Pretrolati, Roma IT
Patent application number | Description | Published |
---|---|---|
20130240014 | VERTICAL ELECTRICAL CONNECTION OF PHOTOELECTROCHEMICAL CELLS - The present invention concerns a vertical electrical connection of photoelectrochemical cells, arranged side-by-side between two opposing substrates, at least one of which is transparent or semi-transparent, and covered, on the side facing towards the other substrate, by an electrically conductive coating divided into a plurality of side-by-side regions electrically isolated by means of a corresponding number of interruptions, said vertical electrical connection being arranged between an electrically isolated region of the electrically conductive coating of a substrate, in electric contact with a photoelectrochemical cell, and the electrically isolated region of the electrically conductive coating of the opposing substrate, in contact with an adjacent photoelectrochemical cell, characterized in that it is made of three overlapping portions, that is two portions, respectively coupled with the conductive coating of each of the two opposing substrates delimiting said photoelectrochemical cells. | 09-19-2013 |
Eleonora Zanderigo, London GB
Patent application number | Description | Published |
---|---|---|
20100212666 | System for Controlling Administration of Anaesthesia - A system for controlling administration of a respiratory depressant drug or mixture of drugs to a spontaneously breathing patient comprises a drug delivery unit ( | 08-26-2010 |