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Ekaterini
Ekaterini Korovessi, Wilmington, DE US
| Patent application number | Description | Published |
|---|---|---|
| 20110300594 | PROCESS FOR MAKING LINEAR DICARBOXYLIC ACIDS FROM RENEWABLE RESOURCES - This invention provides a process of making a linear dicarboxylic acid of C | 12-08-2011 |
Ekaterini Kotsopoulou, Kent GB
| Patent application number | Description | Published |
|---|---|---|
| 20110040074 | PRODUCTION METHODS - The present invention provides methods of reducing the levels of a titratable selectable pressure required, the number of amplification cycles, and the time taken to generate protein expressing cell lines by altering the codons of the desired open-reading-frames. Through the use of codon adaptation for this purpose the methods of the invention consistently provide sufficient yields in faster time frames saving many weeks in cell line development activities. Furthermore the methods of the invention also generate cell lines with lower concentrations of selection and amplification agent than previously achievable. Accordingly lower levels of selection and amplification marker in the final cells lines are observed. | 02-17-2011 |
Ekaterini Kotsopoulou, Cambridge GB
| Patent application number | Description | Published |
|---|---|---|
| 20080269473 | Method - A method of producing a replication defective retrovirus comprising transfecting a producer cell with the following: iii) a retroviral genome; iv) a nucleotide sequence coding for retroviral gag and pol proteins; and iii) nucleotide sequences encoding other essential viral packaging components not encoded by the nucleotide sequence of (ii); characterised in that the nucleotide sequence coding for retroviral gag and pol proteins is codon optimised for expression in the producer cell. | 10-30-2008 |
| 20100273996 | Method - A method of producing a replication defective retrovirus comprising transfecting a producer cell with the following: iii) a retroviral genome; iv) a nucleotide sequence coding for retroviral gag and pot proteins; and iii) nucleotide sequences encoding other essential viral packaging components not encoded by the nucleotide sequence of (ii); characterised in that the nucleotide sequence coding for retroviral gag and pot proteins is codon optimised for expression in the producer cell. | 10-28-2010 |