Patent application number | Description | Published |
20090275049 | EphA4 POLYPEPTIDE HAVING A NOVEL ACTIVITY AND USE THEREOF - The present invention provides a polynucleotide which consists of a partial sequence of a polynucleotide encoding the amino acid sequence as shown in SEQ ID NO: 2, wherein the former polynucleotide encodes a polypeptide consisting of a partial amino acid sequence of SEQ ID NO: 2 whose N-terminus starts between positions 564 and 621 of SEQ ID NO: 2. | 11-05-2009 |
20100190184 | SCREENING METHOD UTILIZING NOVEL SUBSTRATE C-RET FOR GAMMA-SECRETASE - The present invention provides a method of screening for compounds which affect the processing of c-Ret by γ-secretase. The method involves contacting a first biological composition containing γ-secretase or a biologically active fragment thereof with a second biological composition containing c-Ret in the presence and absence of a candidate compound; measuring the cleavage of the c-Ret in the presence and absence of the candidate compound; selecting those candidate compounds which affect the cleavage of the c-Ret by γ-secretase; and identifying the candidate compounds selected in the previous step as compounds which affect the processing of c-Ret by γ-secretase. | 07-29-2010 |
20110104171 | EphA4 Polypeptide Having a Novel Activity and Use Thereof - The present invention provides a polynucleotide which consists of a partial sequence of a polynucleotide encoding the amino acid sequence as shown in SEQ ID NO:2, wherein the former polynucleotide encodes a polypeptide consisting of a partial amino acid sequence of SEQ ID NO:2 whose N-terminus starts between positions 564 and 621 of SEQ ID NO:2. | 05-05-2011 |
20130288278 | SCREENING METHOD USING GELATINASE-MEDIATED EphA4 CLEAVAGE REACTION AS AN INDICATOR - The object of the present invention is to provide a method for screening a substance that affects gelatinase-mediated EphA4 processing. The present invention provides a method for screening a substance that affects gelatinase-mediated EphA4 processing, which comprises the steps of: (a) allowing a first biological composition containing gelatinase or a biologically active fragment thereof to be contacted with a second biological composition containing EphA4 in the presence and absence of a candidate substance; (b) measuring the presence or amount of the EphA4 ectodomain and/or endodomain fragment; and (c) selecting the candidate substance as a substance that affects gelatinase-mediated EphA4 processing if the results of the step (b) measured in the presence of the candidate substance are changed in comparison with the results of the step (b) measured in the absence of the candidate substance. | 10-31-2013 |
Patent application number | Description | Published |
20090318260 | TOROIDAL CONTINUOUSLY VARIABLE TRANSMISSION UNIT AND CONTINUOUSLY VARIABLE TRANSMISSION - In this toroidal continuously variable transmission unit, a carrier | 12-24-2009 |
20110130244 | TOROIDAL CONTINUOUSLY VARIABLE TRANSMISSION - A toroidal continuously variable transmission of the present invention comprises: input side disks ( | 06-02-2011 |
20140024487 | FRICTION ROLLER REDUCER AND DRIVE UNIT FOR ELECTRIC AUTOMOBILE - Construction of a friction roller reducer is achieved wherein displacement of intermediate rollers due to the change in thickness in the axial direction of loading cam apparatuses can be performed smoothly, and excellent transmission efficiency can be obtained. Long guide holes that are long in the radial direction of a sun roller and ring-shaped roller are provided in guide blocks that are fastened to a support frame for supporting the end sections of rotation shafts of intermediate rollers. The outer rings of ball bearings, of which the inner rings are fitted around and fastened to the outside of the end sections of the rotation shafts, engage with the long guide holes so as to be able to displace in the radial direction of the sun roller and the ring-shaped roller. | 01-23-2014 |
20140287863 | DRIVE APPARATUS FOR AN ELECTRIC AUTOMOBILE - Construction capable of improving the convenience of an electric automobile is achieved by making the drive apparatus for an electric automobile in which a planetary-gear transmission | 09-25-2014 |
20150018167 | ELECTRIC AUTOMOBILE DRIVE APPARATUS - Construction of an electric automobile drive apparatus is realized in which the relationship of the traveling speed and acceleration of a vehicle can be made smooth and closer to the ideal, and the transmission efficiency can be maintained. A bypass gear-transmission mechanism | 01-15-2015 |