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Ehwald
Karl-Ernst Ehwald, Frankfurt DE
| Patent application number | Description | Published |
|---|---|---|
| 20100207216 | CORROSION-RESISTANT MEMS COMPONENT AND METHOD FOR THE PRODUCTION THEREOF - An MEMS component including a monolithically integrated electronic component with a multi-plane conductor track layer stack which is arranged on a substrate and into which is integrated a cantilevered elastically movable metallic actuator which is arranged in the multi-plane conductor track layer stack at the level of a conductor track plane and is connected by via contacts to conductor track planes which are arranged thereabove or therebeneath and which apart from an opening in the region of the actuator are separated from the conductor track plane of the actuator by a respective intermediate plane insulator layer, wherein the actuator is formed from a metallically conductive layer or layer combination which is resistant to corrosive liquids or gases and which contains titanium nitride or consists of titanium nitride. | 08-19-2010 |
Karl-Ernst Ehwald, Frankfurt (oder) DE
| Patent application number | Description | Published |
|---|---|---|
| 20100019326 | COMPLEMENTARY BIPOLAR SEMICONDUCTOR DEVICE - A complementary bipolar semiconductor device (CBi semiconductor device) comprising a substrate of a first conductivity type, active bipolar transistor regions in the substrate, in which the base, emitter and collector of vertical bipolar transistors are arranged, vertical epitaxial-base npn bipolar transistors in a first subset of the active bipolar transistor regions, vertical epitaxial-base pnp bipolar transistors in a second subset of the active bipolar transistor regions, collector contact regions which are respectively arranged adjoining an active bipolar transistor region, and shallow field insulation regions which respectively laterally delimit the active bipolar transistor regions and the collector contact regions, wherein arranged between the first or the second or both the first and also the second subset of active bipolar transistor regions on the one hand and the adjoining collector contact regions on the other hand is a respective shallow field insulation region of a first type with a first depthwise extent in the direction of the substrate interior and shallow field insulation regions of a second type of a second greater depthwise extent than the first depthwise extent of the active bipolar transistor regions delimit the active bipolar transistor regions and collector contact regions viewed in cross-section at their sides facing away from each other. | 01-28-2010 |
Rudolf Ehwald, Berlin DE
| Patent application number | Description | Published |
|---|---|---|
| 20110066103 | MICRO-DIALYSIS PROBE - A micro-dialysis probe extending longitudinally between a proximal probe opening and a distal probe tip and having a supply line and a drainage line for a drip-feed solution. A tube may be provided for supporting the drainage line. A dialysis section, wherein the flow channel for the drip-feed solution experiences an inversion, is formed generally between the supply line and the drainage line, in the vicinity of the distal probe tip. The supply line and the drainage line are respectively arranged substantially side by side and together form the probe shaft of the micro-dialysis probe. | 03-17-2011 |
| 20110098462 | METHOD AND KIT FOR THE SAMPLE PRESERVATION AND CELL DISRUPTION BEFORE THE EXTRACTION OF NUCLEIC ACIDS - The invention relates to a method for preserving samples and disrupting cells which can be employed for the preparation of the extraction of nucleic acids from live cells, cell aggregates and tissue samples, and to a kit for carrying out the method. The method includes the introduction of live cells, cell aggregates or tissue samples whose nucleic acids are to be extracted into an excess of water-miscible and volatile organic liquid. The saturation of the sample with the organic liquid has an advantageous effect on the extraction of the nucleic acids, which is subsequently carried out in an aqueous medium. The mechanical cell disruption is facilitated by the virtually complete removal of the water from the cells. The biomembranes are dissolved in the organic liquid. tRNA and other RNA fractions with a low degree of polymerization, which are capable of permeating across the cell wall, can be extracted selectively without mechanical disruption. Before high-molecular-weight nucleic acids are extracted, the cells, cell aggregates or tissue samples are disrupted in the organic liquid with the aid of mechanical pulses. Since the nucleases are inactive in the dehydrated organic liquid, the biological samples or the homogenates prepared therefrom can be stored at room temperature in the organic liquid as long as desired. After incubation in the largely anhydrous organic liquid, the sample's nucleases are largely denatured. An advantageous kit according to the invention contains a mixed organic/aqueous phase with denaturing properties and, for each sample, a shaped body for dehydration which is adapted to suit the size of the preservation container, and a mixture, adapted to suit the size of the preservation container, of a few large and many small disruption bodies for the disruption in the nonaqueous medium. A considerable advantage of the invention is the fact that cooling and powerful mechanical pulses when disrupting the cells and during the extraction may be dispensed with, and that DNA extraction and cell disruption can be carried out at different times. | 04-28-2011 |