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| 20090253614 | ORAL INSULIN THERAPIES & PROTOCOL - Methods for treating impaired glucose tolerance and early and late stage diabetes in mammals, for prophylactically sparing β-cell function, aiding in preventing β-cell death, preventing the onset of overt diabetes in a mammal with type 2 diabetes, treating the current level of glycemic control dysfunction of a mammal with impaired glucose tolerance or diabetes, comprising orally administering insulin and a delivery agent that facilitates insulin absorption from the gastrointestinal tract at the time of or shortly before mealtime, e.g., within about 10 minutes prior to ingestion of a meal, on a chronic basis. The methods also comprise, in addition to administering a rapid-acting insulin to provide a first insulin peak, administering a slow acting insulin to provide a second insulin peak occurring at a later time but of a longer duration. These methods achieve improved glycemic control without the risks of hypoglycemia, hyperinsulinemia and weight gain and the need for frequent blood glucose monitoring that are normally associated with insulin therapy. | 10-08-2009 |
| 20090318331 | ORAL INSULIN THERAPIES AND PROTOCOL - Methods for treating impaired glucose tolerance and early and late stage diabetes in mammals, for prophylactically sparing β-cell function, aiding in preventing β-cell death, preventing the onset of overt diabetes in a mammal with type 2 diabetes, treating the current level of glycemic control dysfunction of a mammal with impaired glucose tolerance or diabetes, comprising orally administering insulin and a delivery agent that facilitates insulin absorption from the gastrointestinal tract at the time of or shortly before mealtime, e.g., within about 10 minutes prior to ingestion of a meal, on a chronic basis. The methods also comprise, in addition to administering a rapid-acting insulin to provide a first insulin peak, administering a slow acting insulin to provide a second insulin peak occurring at a later time but of a longer duration. These methods achieve improved glycemic control without the risks of hypoglycemia, hyperinsulinemia and weight gain and the need for frequent blood glucose monitoring that are normally associated with insulin therapy. | 12-24-2009 |
| 20100048454 | Antidiabetic oral insulin-biguanide combination - Pharmaceutical dosage forms, comprising insulin, a delivery agent that facilitates insulin transport in a therapeutically effective amount to the bloodstream and a biguanide, such as metformin, are disclosed for oral administration to a patient for the treatment of diabetes. Also disclosed are methods for achieving improved glucose tolerance and glycemic control in a diabetic mammal without any statistically significant increase in weight, risk of hypoglycemia or hyperinsulinemia, and the need for monitoring blood glucose concentrations or HbAlc levels, and methods for reducing the incidence and/or severity of one or more disease states associated with chronic dosing of insulin; for prophylactically sparing (3-cell function or for preventing (3-cell death or dysfunction in a mammal with impaired glucose tolerance or early stage diabetes mellitus; and for long-term protection from developing (or delaying the onset of) overt or insulin dependent diabetes in a mammal with impaired glucose tolerance or early stage diabetes. | 02-25-2010 |
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| 20080207514 | Intraoral Dosage Forms of Glucagon - The present invention provides a composition (e.g., a pharmaceutical composition) comprising at least one delivery agent compound and glucagon. Preferably, the composition includes a therapeutically effective amount of glucagon and the delivery agent compound. The composition of the present invention facilitates the delivery of glucagon and increases its bioavailability compared to administration without the delivery agent compound. | 08-28-2008 |
| 20090209635 | TOPICAL CROMOLYN FORMULATIONS - The present invention provides a topical composition comprising (a) at least one delivery agent compound and (b) a cromoglycic acid compound. Methods of treatment, and methods of preparing the topical composition are also provided. | 08-20-2009 |
| 20100055194 | PHARMACEUTICAL FORMULATIONS CONTAINING MICROPARTICLES OR NANOPARTICLES OF A DELIVERY AGENT - This invention relates to microparticles and/or nanoparticles containing a delivery agent and/or an active agent. This invention also relates to pharmaceutical formulations and solid dosage forms, including controlled release solid dosage forms of active agent and a delivery agent. | 03-04-2010 |
| 20110142800 | METHODS AND COMPOSITIONS FOR ORAL ADMINISTRATION OF PROTEINS - This invention provides compositions comprising a protein, an absorption enhancer, a protease inhibitor, methods for treating diabetes mellitus, comprising administering same, and methods for oral administration of a protein with an enzymatic activity, comprising orally administering same. | 06-16-2011 |
| 20120089048 | REDUCED-PAIN ALLERGY SKIN TEST DEVICE - An allergy skin test device is disclosed that causes less pain than commonly used devices that include multi-point sharp puncture heads. The allergy skin test device incorporates multiple dull pressure heads distributed amongst the sharp multi-point sharp puncture heads, each dull pressure head activating a neurological pain gate that reduces pain sensation typically caused by the neighboring multi-point head when it engages the skin. | 04-12-2012 |
| 20120189666 | PHARMACEUTICAL FORMULATIONS CONTAINING MICROPARTICLES OR NANOPARTICLES OF A DELIVERY AGENT - This invention relates to microparticles and/or nanoparticles containing a delivery agent and/or an active agent. This invention also relates to pharmaceutical formulations and solid dosage forms, including controlled release solid dosage forms of active agent and a delivery agent. | 07-26-2012 |
| 20120253314 | PALM-CONTROLLED INJECTORS - A palm-controlled device is disclosed for injection of a substance into an organism. The device includes a palm-receiving surface for receiving a palm of a hand, the palm receiving surface being shaped so that the palm is substantially parallel to a surface of an injection site of the organism while operating the device. The palm receiving surface can also be shaped so that the palm is substantially perpendicular to a surface of the injection site. The device also includes an injector having at least one pre-filled syringe, the palm-receiving surface being cooperative with the injector such that when pressure is applied to the palm-receiving surface, the injector is actuated so as to inject contents of the at least one pre-filled syringe. Actuation of the injector is by gradual pressure; not sudden motion. Single or multiple doses of same or different medications can be included in a single injector. | 10-04-2012 |
| 20120308094 | SYSTEM FOR BREAST EXAMINATION RESULT MAPPING, RECORDING, COMPARING, AND/OR TRACKING - A breast examination system is disclosed that facilitates normalized quantitative comparison of results from multiple examinations performed under differing conditions, such as different viewing angles. The proposed system can operate on a camera-equipped smart-phone, a camera-equipped desk-top computer, or on a dedicated device to perform a guided breast cancer examination, and then store results of the examination in a normalized format that allows effective quantitative comparison to historic results, thereby detecting changes and trends. The results can be stored on the local device, or on a web-based server, providing various data comparison, data management, and data interpretation services in a secure and controlled manner. | 12-06-2012 |
| 20130017247 | TREATMENT AND/OR PREVENTION OF ORAL ALLERGIC SYMPTOMS CAUSED BY ORAL CONTACT WITH FRUITS AND/OR VEGETABLES - Treatment or prevention of oral allergy syndrome, or other allergy-related oral inflammatory processes using a topical preparation of at least one of a mast cell stabilizer and an antihistamine is disclosed. For example, the topical administration of Cromolyn Sodium prior to ingestion of raw fruits and raw vegetables may be used to prevent oral allergy symptoms. The topical administration can be performed by use of a solution, a powder, an aerosol, a tablet, a chewable tablet, a gel, a melting strip, a mouth rinse, a mouth swab, or a piece of candy, and may be combined with carrier molecules and/or mucoadhesive molecules to enhance efficacy. | 01-17-2013 |
| 20130030009 | METHOD FOR THE TREATMENT AND/OR PREVENTION OF ORAL ALLERGIC SYMPTIONS OF THE LIPS DUE TO ORAL CONTACT WITH A FOOD ALLERGEN - A method of applying a topical preparation of at least one of a mast cell stabilizer, an antihistamine, and a leukotriene inhibitor is disclosed for prevention and/or treatment of oral allergy syndrome of the lips, including lip itchiness and/or swelling. For example, topical application of Cromolyn Sodium to the lips can be used to prevent and/or treat allergic reaction to consumption or other contact with raw fruits and/or raw vegetables. The topical administration can be performed by using applicator devices that apply at least one of a mast cell stabilizer and an antihistamine in the form of a liquid, or a gel, or a butter, or a wax-like solid, or a liposome suspension. Applicator devices can include at least one of: a roller, a brush, a sponge, a swab, a tube, a lipstick. The taste of the at least one of a mast cell stabilizer and an antihistamine can be masked by flavors. | 01-31-2013 |
| 20130031016 | SYSTEM FOR POSTING PROFILES OF ANONYMOUS INDIVIDUALS AND FOR ENABLING POTENTIAL EMPLOYERS TO DISCOVER AND TO COMMUNICATE WITH THE ANONYMOUS INDIVIDUALS - A website and method are disclosed for helping an anonymous individual to publicly disclose anonymous information about the anonymous individual so as to facilitate discovery of the anonymous individual by potential employers interested in hiring the anonymous individual. The website and method reduce risk to the anonymous individual of negative consequences of public disclosure of information about the anonymous individual. The website and method also inherently encourage disclosure to potential employers of more comprehensive information about the anonymous individual. The website includes a profile input capability for use by an anonymous individual to create a profile having anonymous information about the anonymous individual; a profile presentation capability for use by potential employers to view and select profiles of anonymous individuals; and a communication capability for potential employers to communicate with a selected anonymous individual so as to preserve the anonymity of the selected anonymous individual. | 01-31-2013 |
| 20130031451 | SYSTEM FOR EFFICIENT DISTRIBUTION AND RETAINED CONTROL OF CONFIDENTIAL RECOMMENDATIONS OF INDIVIDUALS - A website and method are disclosed for helping a recommender to provide confidential recommendations for individuals. The system enables the recommender to efficiently comply with multiple requests for confidential recommendations, and to efficiently comply with a single request for a confidential recommendation to be sent to multiple institutions. The system eliminates the need to write multiple confidential recommendations when the individual applies to multiple institutions by enabling the recommender to distribute multiple links to the same confidential recommendation. The system also enables the recommender to easily edit the recommendation before or after multiple links have been distributed, thereby ensuring that the recommender retains control over the content of the confidential recommendation. The control over the recommendation link also includes a capability for changing the link expiration date, temporarily suspending or re-activating a link, and deleting a link. | 01-31-2013 |
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| 20080215619 | Financial line data-base - A computerized method for managing data performed in a computer system. The data is stored in a data base including flat lines. Each of the flat lines includes values of the data and tags associated with the values forming tag-value pairs. The flat lines are scanned and an object of a class is created. The class specifies a subset including one or more tags selected from the tags of the flat lines. The flat line points to the object if a portion of the tag-value pairs of the flat line includes all the tags of the subset. When the flat line contains multiple alternative ways, through the subset(s) of tags or through different tag-value pairs, of pointing to the object of the class, then the object as individually identified by the alternative ways is taken to be the same object. | 09-04-2008 |
| 20110035347 | SYSTEMS AND METHODS FOR IDENTIFYING PROVIDER NONCUSTOMERS AS LIKELY ACQUISITION TARGETS - The present invention is directed towards systems and methods for predicting one or more desired properties of external nodes or properties of their relations with internal nodes, based on a selected group of nodes about which it is known whether the nodes have the desired properties, or it is known whether they have a desired relation property with an internal node. The method comprises storing in one or more data structures a first data set regarding external nodes and a second data set regarding nodes with known properties in a selected group, each data set having one or more data items representing one or more events relating to or attributes of each node in the data set, the second data set including one or more types of data items not included in the first data set. The method then models the second data set to identify from the second data one or more modeled events or attributes of internal nodes in the selected group that are statistically likely to identify the nodes or their relations, that have the desired properties and predicts which of the external nodes are statistically likely to have the one or more desired properties, or desired relation property with internal node, based on the identified plurality of modeled events or attributes and the events or attributes in the first data set. | 02-10-2011 |
| 20110213741 | SYSTEMS AND METHODS FOR GENERATING LEADS IN A NETWORK BY PREDICTING PROPERTIES OF EXTERNAL NODES - The present invention is directed towards systems and methods for predicting one or more desired properties of external nodes or properties of their relations with internal nodes, based on a selected group of nodes about which it is known whether the nodes have the desired properties, or it is known whether they have a desired relation property with an internal node. The method comprises storing in one or more data structures a first data set regarding external nodes and a second data set regarding nodes with known properties in a selected group, each data set having one or more data items representing one or more events relating to or attributes of each node in the data set, the second data set including one or more types of data items not included in the first data set. The method then models the second data set to identify from the second data one or more modeled events or attributes of internal nodes in the selected group that are statistically likely to identify the nodes or their relations, that have the desired properties and predicts which of the external nodes are statistically likely to have the one or more desired properties, or desired relation property with internal node, based on the identified plurality of modeled events or attributes and the events or attributes in the first data set. | 09-01-2011 |
| 20120198056 | Techniques for Analyzing Website Content - A scheme for analyzing businesses and generating business leads is disclosed. A list of company websites can be gathered from a plurality of data sources and combined to produce an aggregated list of companies. Content from the websites of the companies in the list is extracted and stored. Contact information may automatically be ascertained from the website content, if available. The stored content extracted from the websites may then be analyzed to detect the presence of particular features. The listing of companies may then be filtered to produce a subset of businesses that represent potential business leads. The business leads may be provided to a company seeking such leads, and may optionally be provided to an automated marketing system, which is configured to generate and transmit commercial advertisements to the businesses identified as leads. | 08-02-2012 |
| 20120265610 | Techniques for Generating Business Leads - A scheme for analyzing businesses and generating business leads is disclosed. A list of company websites can be gathered from a plurality of data sources and combined to produce an aggregated list of companies. Content from the websites of the companies in the list is extracted and stored. Contact information may automatically be ascertained from the website content, if available. The stored content extracted from the websites may then be analyzed to detect the presence of particular features. The listing of companies may then be filtered to produce a subset of businesses that represent potential business leads. The business leads may be provided to a company seeking such leads, and may optionally be provided to an automated marketing system, which is configured to generate and transmit commercial advertisements to the businesses identified as leads. | 10-18-2012 |
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| 20080313734 | DISTRIBUTED SYSTEM AND METHOD FOR THE DETECTION OF eTHREATS - The invention relates to a distributed system for detecting eThreats that propagate in a network, which comprises: (a) graphs database storing at least one propagation graph, each graph describing the typical propagation over time of one eThreat class or a legitimate executable class within the network; (b) plurality of agents that are distributed in corresponding plurality of hosts within the network, each of said agents continuously monitoring the corresponding host and reporting to a Central Decision Maker (CDM) the identity of any new suspected executable, and the time in which said suspected executable has been first detected by said agent; (c) a CDM for: (c.1) receiving all said reports from said plurality of agents; (c.2) creating from said reports for each suspected executable a corresponding propagation graph which reflects the propagation characteristics over time of said suspected executable within the network, and (c.3) comparing each of said created graphs with said stored at least one propagation graph; (c.4) upon finding a similarity above a predefined threshold between a created graph and one of the stored graphs, concluding respectively that said executable belongs to the class as defined by said stored graph; and (c.5) conveying said conclusion to said agents, for optionally taking an appropriate action. | 12-18-2008 |
| 20100229239 | SYSTEM AND METHOD FOR DETECTING NEW MALICIOUS EXECUTABLES, BASED ON DISCOVERING AND MONITORING CHARACTERISTIC SYSTEM CALL SEQUENCES - The invention relates to a method for detecting malicious executables, which comprises: (a) in an offline training phase, finding a collection of system call sequences that are characteristic only to malicious files, when such malicious files are executed, and storing said sequences in a database; and, in runtime, for each running executable, continuously monitoring its issued run-time system calls and comparing with the stored sequences of system calls within the database to determine whether there exists a match between a portion of the sequence of the run-time system calls and one or more of the database sequences, and when such a match is found, declaring said executable as malicious. | 09-09-2010 |
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| 20080240318 | Recovering precoded data using a Mueller-Muller recovery mechanism - In one embodiment, the present invention includes an apparatus having a digital signal processor (DSP) coupled to receive a digitized signal. The DSP may be controlled to perform a timing recovery mechanism that implements a Mueller and Müller (MM)-based algorithm to generate a sensor output responsive to the digitized signal, where the incoming signal is non-linearly precoded in a transmitter from which the signal is received. Other embodiments are described and claimed. | 10-02-2008 |
| 20080240412 | Maintaining convergence of a receiver during changing conditions - In one embodiment, the present invention includes an apparatus having an automatic gain control (AGC) stage to receive an input signal from a communication channel physical medium, a first local gain stage coupled to an output of the AGC stage, an equalizer coupled to an output of the first local gain stage, an echo canceler to receive local data to be transmitted along the communication channel physical medium, and a second local gain stage coupled to an output of the echo canceler. Other embodiments are described and claimed. | 10-02-2008 |
| 20090168672 | METHODS AND APPRATUS FOR SIGNAL ECHO CANCELLATION AND TRANSMITTER CALIBRATION IN FULL DUPLEX SYSTEMS - A method includes transmitting a first signal over a network from a first communication link to a second communication link. The method further includes receiving a second signal with the first communication link from the second communication link. The method further includes canceling signal echo from the first signal present in the second signal with a digital echo canceller. The method further includes providing correction data from a memory array to the digital echo canceller during the cancellation of the signal echo. An associated apparatus is also disclosed. | 07-02-2009 |
| 20090245448 | Adaptation of a digital receiver - A method and apparatus to improve adaptation speed of a digital receiver is presented. The receiver includes an equalizer to initiate adaptation to a transmission channel responsive to a first control signal, a slicer coupled to the equalizer to generate symbol decisions based at least in part on an equalized digital signal, logic to receive the symbol decisions and generate a selection signal when a lock onto a training sequence of the symbol decisions occurs, first and second phase detectors to detect phase errors of the equalized digital signal and an incoming digital signal, respectively, and a clock generator to generate a clock signal responsive to one of the first and second phase errors. | 10-01-2009 |
| 20120076508 | JITTER REDUCTION OF ELECTRICAL SIGNALS FROM LIMITING OPTICAL MODULES - Jitter reduction of electrical signals from limiting optical modules is described. In one example, a process includes receiving an amplitude limited electrical signal that has been converted from an optical signal, applying a filter to the received electrical signal, measuring an indication of jitter of the filtered signal, and selecting parameters of the linear filter based on the measured indication. | 03-29-2012 |
| 20120154185 | Providing A Feedback Loop In A Low Latency Serial Interconnect Architecture - In one embodiment, the present invention includes a de-serializer to receive serial data at a first rate and to output a parallel data frame corresponding to the serial data aligned to a frame alignment boundary in response to a phase control signal received from a feedback loop coupled between the de-serializer and a receiver logic coupled to an output of the de-serializer. Other embodiments are described and claimed. | 06-21-2012 |
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| 20090130638 | Self Adjusting Instrument - The invention is an instrument for cleaning and/or shaping and/or widening a channel that exists in or through a solid object. The design of the instrument the superelastic and shape memory properties of the material from which it is made, allow the inner volume enclosed by the instrument, its outer contour, or both to change as a result of the forces exerted upon it while working, thereby shaping the instrument to the three-dimensional contour of the channel. A preferred embodiment of the instrument is an endodontic file for use in the cleaning, shaping, and widening stages of a root canal procedure. | 05-21-2009 |
| 20110081623 | SELF ADJUSTING INSTRUMENT - The invention is an instrument for cleaning and/or shaping and/or widening a channel that exists in or through a solid object. The design of the instrument the superelastic and shape memory properties of the material from which it is made, allow the inner volume enclosed by the instrument, its outer contour, or both to change as a result of the forces exerted upon it while working, thereby shaping the instrument to the three-dimensional contour of the channel. A preferred embodiment of the instrument is an endodontic file for use in the cleaning, shaping, and widening stages of a root canal procedure. | 04-07-2011 |
