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| 20100069479 | NEURODEGENERATIVE DISEASE TREATMENT USING JAK/STAT INHIBITION - The invention relates to treatment of neurodegenerative diseases with JAK/STAT pathway inhibitors to eliminate extracellular cell signaling events leading to cell cycle abrogation and/or apoptosis. Primary neurons were administered neurotoxic proteins, such as gp120, Tat, or gp120 and Tat, with or without IFN-γ added, resulting in neuronal death, and simulated neurodegenerative diseases. The neurodegenerative disease is treated using a JAK/STAT pathway inhibitor, including (—)-epigallocatechin-3-gallate (EGCG), to modulate JAK1 or STAT1 phosphorylation, resulting in resistance to gp120 or Tat neurotoxicity. The invention may be used to treat neurons afflicted with HIV-associated Dementia, multiple sclerosis, Alzheimer's Disease, Parkinson's Disease, amyotrophic lateral sclerosis, or Pick's Disease, and may act in conjunction with antiviral treatment, like HAART. | 03-18-2010 |
| 20100267733 | Synergistic Modulation of Microglial Activation by Nicotine and THC - Treatment of microglial cells with nicotine and THC synergistically attenuate the microglial activation. Using microglial activation, the combination of THC and nicotine interact synergistically reduced LPS induced TNF-α release, showing that the combination of THC and nicotine clinically have greater efficacy in reducing neuroinflammation with less side effects than either drug given alone. CD40 signaling was found critically involved in pathological activation of microglial cells. This invention is also relevant to peripheral inflammation as well thru macrophages. In addition, other cannabinoids and other nicotinic-like medications currently in development are also covered under this discovery. | 10-21-2010 |
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| 20090045259 | OPTICAL READER HAVING A COLOR IMAGER - There is described a device having a two dimensional imager. The device having a two dimensional image sensor can be a hand held device. Imaging optics can be provided for focusing light reflected from a target onto the two dimensional imager. A two dimensional image sensor can be a color image sensor adapting the hand held device for use in obtaining a color image having color imaging data. Color imaging data obtained can be subject to processing. | 02-19-2009 |
| 20100001073 | IMAGE CAPTURE APPARATUS AND METHOD - There is provided an image capture apparatus and method. An image capture device can be used in the decoding of a decodable indicia, e.g., bar code symbols and/or text characters and can further be used in the capture of one or more images that may or may not be subjected to decoding processes. In one embodiment, an image captured with use of an image capture device is an image of an item bearing a decodable indicia. In one embodiment, an image capture device can have a plurality of user selectable modes of operation. | 01-07-2010 |
| 20100176201 | OPTICAL READER HAVING AN IMAGER - There is described a device having a two dimensional imager. The device having a two dimensional image sensor can be a hand held device. Imaging optics can be provided for focusing light reflected from a target onto the two dimensional imager. An image including imaging data can be obtained utilizing the hand held device. The image can include a representation of a signature. | 07-15-2010 |
| 20110121076 | IMAGE SENSOR BASED OPTICAL READER - An apparatus for use in optical reading can comprise an image sensor and a circuit board, and can further comprise a support assembly. An apparatus for use in optical reading can also comprise a light source and imaging optics. | 05-26-2011 |
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| 20090039167 | Indicia reading terminal having spatial measurement functionality - There is provided in one embodiment an indicia reading terminal that can execute a spatial measurement mode of operation in which the indicia reading terminal can determine a dimension of an article in a field of view of the indicia reading terminal and/or determine other spatial information. In determining a dimension of an article, an indicia reading terminal can utilize setup data determined in a setup mode of operation and/or data determined utilizing the setup data. | 02-12-2009 |
| 20090236424 | IMAGE SENSOR BASED OPTICAL READER - An optical reader can include an image sensor. In one embodiment an optical reader can be configured to have different operating modes, the different operating modes optimizing the reader for reading different indicia. In another embodiment an optical reader can comprise a multiple color emitting light source. In another embodiment an optical reader can be provided in a specialized form factor including an enlarged head portion and an elongated body portion extending from the head portion. | 09-24-2009 |
| 20090308927 | Bar Code Reading Device For Reading 1D Or 2D Bar Code Symbols - The present invention relates to a bar code reading device for reading 1D or 2D bar code symbols. The bar code reading device, in one embodiment, can receive a command to disable symbology reading. In another embodiment, a bar code reading device can have a timercount and an image memory. In one embodiment, a bar code reading device can be configured to read bar code symbols of more than one bar code symbology. | 12-17-2009 |
| 20100140356 | APPARATUS COMPRISING IMAGE SENSOR - An apparatus having an image sensor is provided. An image sensor of the apparatus can include a two dimensional image sensor. A lens assembly can be provided in combination with an image sensor. In one aspect, an apparatus can attempt to decode a decodable symbol representation. In one aspect an apparatus can output a frame of image data. | 06-10-2010 |
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| 20090071666 | Method for gradually relieving pressure in a hydraulic system utilizing reverse fluid flow through a pump of the system - A method of gradually relieving pressure in a hydraulic system of a work machine, wherein a pump in fluid communication with the hydraulic system and a fluid reservoir, is operable for pressurizing fluid from the reservoir and pumping the pressurized fluid into the hydraulic system, wherein the pump is restrictive to fluid flow therethrough when not operating, and the hydraulic system includes at least one valve in fluid communication with the work element configured for receiving the pressurized fluid. The valve is controllably operable in at least two operating modes, including a first mode wherein the pressurized fluid can pass therethrough between the pump and the work element or elements, and a second mode wherein the fluid is prevented from passing between the pump and the work element. The method includes operating the valve or valves in the first mode for at least a predetermined time period while the pump is not operating, to allow at least some of any of, the pressurized fluid in the work element to flow through the hydraulic system and gradually drain through the pump to the reservoir so as to reduce any pressure in the hydraulic system and the work element. | 03-19-2009 |
| 20090237227 | Cutterbar failure detection system and method - A system and method for detecting impending failure of a component of a disc cutterhead of a cutterbar of a plant cutting machine, the components will generate at least one indicator of an impending failure thereof, utilizing a plurality of sensors distributed among the cutterheads, each of the sensors being configured and operable for sensing at least one of the indicators of impending failure and outputting signals representative thereof to a controller automatically operable for processing the signals, to enable identifying an individual location or one of the cutterheads in which an impending failure of one or more of the components is present, and outputting a signal representative thereof to a warning device. The indicators can include, but are not limited to, temperature, sound, and vibration. The controller is also operable for determining comparative threshold values for the indicators, to adapt to changing conditions and norms. | 09-24-2009 |
| 20100000191 | Header Height Control System and Apparatus - A system and apparatus for controlling height of a header of a work machine such as an agricultural windrowing machine or a harvesting machine, which includes height control cylinders jointly or individually operable for raising or lowering the opposite ends of a header to achieve a desired overall height or angle of tilt in relation to the surface of a field or pasture to be cut, and which allow the header to be raised, and lowered to the previously selected cut height, without changing the lengths of the cylinders, so as to be usable in combination with an optional header lift and/or float system. | 01-07-2010 |
| 20110107733 | APPARATUS TO IMPROVE MODULAR CUTTERBAR CONNECTING SHAFT SPLINE DURABILITY - An improved modular disc cutterhead connecting drive shaft configuration having a means for laterally centering the shaft between adjacent cutterhead modules thereby equalizing engagement on each end of the shaft with the module connectors. Further durability improvement is realized by a structure to radially center the shaft in the shaft receptacles of each module to maintain uniform loading on the shaft/receptacle interface which improves the durability of the connecting drive shaft end connections. Additional connecting shaft durability is provided by a means to lubricate the drive shaft connector connecting interfaces using lubricant reservoirs disposed within the modules. | 05-12-2011 |
| 20110113739 | METHOD AND APPARATUS FOR OILING SPLINES IN A BEVEL GEARBOX - A method and apparatus for providing improved lubrication of a spline connection between a PTO driver and a bevel gearbox in which lubricant from the bevel gear housing is directed to a location above and radially outwardly from the splined connection and the apparatus then directs the lubricant flow toward the splined connection by force of gravity. The apparatus is configured to be self-aligning when installed in an existing receptacle in the gearbox housing thereby enabling the apparatus to be conveniently installed in a housing designed to utilize gearbox lubricant to lubricate the splines. | 05-19-2011 |
