| Patent application number | Description | Published |
|---|
| 20080200418 | COMPOSITIONS FOR DRUG ADMINISTRATION - A composition having at least one alkyl glycoside and at least one therapeutic agent, wherein the alkylglycoside has an alkyl chain length from about 10 to about 16 carbon atoms and wherein the therapeutic agent is an oligonucleotide. | 08-21-2008 |
| 20080268032 | Stabilizing Alkylglycoside Compositions and Methods Thereof - The present invention relates to alkylglycoside-containing compositions and methods for increasing the stability, reducing the aggregation and immunogenicity, increasing the biological activity, and reducing or preventing fibrillar formation of a peptide, polypeptide, or variant thereof, for example amylin, a monoclonal antibody, insulin, Peptide T or analog thereof, gastrin, gastrin releasing peptides, gastrin releasing peptide-like (GRP) proteins, epidermal growth factor or analog thereof. | 10-30-2008 |
| 20080299079 | Absorption Enhancers for Drug Administration - A composition including a surfactant and at least one alkyl glycoside and/or saccharide alkyl ester and a drug. The surfactant composition(s) when admixed with a drug is non-toxic and non-irritating, while stabilizing and increasing the bioavailability of the drug. The invention also provides compositions that enhance absorption of drugs via the oral, ocular, nasal, nasolacrimal, inhalation or pulmonary, oral cavity (sublingual or Buccal cell) or CSF delivery route of a patient, including but not limited to insulin, glucagon and exendin-4. | 12-04-2008 |
| 20090024332 | DIAGNOSING INAPPARENT DISEASES FROM COMMON CLINICAL TESTS USING BAYESIAN ANALYSIS - A system and method of diagnosing diseases from biological data is disclosed. A system for automated disease diagnostics prediction can be generated using a database of clinical test data. The diagnostics prediction can also be used to develop screening tests to screen for one or more inapparent diseases. The prediction method can be implemented with Bayesian probability estimation techniques. The system and method permit clinical test data to be analyzed and mined for improved disease diagnosis. | 01-22-2009 |
| 20090047347 | Compositions for Drug Administration - The present invention provides compositions and methods and for speeding the onset of drug action and reducing the first-pass effect drug metabolism in fast-dispersing drug formulations. | 02-19-2009 |
| 20090095133 | METHODS, COMPOSITIONS, AND DEVICES FOR SAFE STORAGE, TRANSPORT, DISPOSAL AND RECYCLING OF MERCURY CONTAINING LIGHT BULBS - The present invention provides methods and devices for the safe and cost efficient storage, transport and disposal of mercury. A puncture resistant container is provided having an interior element comprising a mercury sequestering substance to permit the safe storage, transport or disposal of mercury containing light bulbs and to capture mercury vapor by chemical sequestration in the event that the bulb breaks during storage, transport or disposal. The mercury sequestering element may be removable to facilitate further processing and reclamation of sequestered mercury using various methods known in the art. | 04-16-2009 |
| 20090110735 | CONTROLLED RELEASE FORMULATIONS - The present invention provides stable, self-assembling, biocompatible and biodegradable hydrogel formulations, into which one or more compounds may be incorporated allowing for delayed release or controlled release of the incorporated compounds as the hydrogel is degraded in the body. | 04-30-2009 |
| 20090163447 | Compositions for Drug Administration - The present invention provides compositions and methods and for increasing the bioavailability of therapeutic agents in a subject. The compositions include at least one alkyl glycoside and at least one therapeutic agent, wherein the alkylglycoside has an alkyl chain length from about 10 to about 16 carbon atoms. | 06-25-2009 |
| 20090197816 | Stabilizing Alkylglycoside Compositions and Methods Thereof - The present invention relates to alkylglycoside-containing compositions and methods for increasing the stability, reducing the aggregation and immunogenicity, increasing the biological activity, and reducing or preventing fibrillar formation of a peptide, polypeptide, or variant thereof, for example amylin, a monoclonal antibody, insulin, Peptide T or analog thereof, gastrin, gastrir releasing peptides, gastrin releasing peptide-like (GRP) proteins, epidermal growth factor or analog thereof. | 08-06-2009 |
| 20090305958 | STABILIZING ALKYLGLYCOSIDE COMPOSITIONS AND METHODS THEREOF - The present invention relates to alkylglycoside-containing compositions and methods for increasing the stability, reducing the aggregation and immunogenicity, increasing the biological activity, and reducing or preventing fibrillar formation of a peptide, polypeptide, or analog thereof, for example parathyroid hormone (PTH) or PTH analogs, amylin, insulin, Peptide T or analog thereof, gastrin, gastrin releasing peptides, gastrin releasing peptide-like (GRP) proteins, epidermal growth factor or analog thereof. | 12-10-2009 |
| 20090326193 | STABILIZING ALKYLGLYCOSIDE COMPOSITIONS AND METHODS THEREOF - The present invention relates to alkylglycoside-containing compositions and methods for preventing loss of a parathyroid hormone (PTH) analog or octreotide via denaturation due to adherence upon contact with glass. | 12-31-2009 |
| 20100068209 | ANTIBACTERIAL COMPOSITIONS FOR DRUG ADMINISTRATION - Non-toxic aqueous compositions are provided having antibacterial activity. Specifically, the invention provides aqueous alkyl glycoside or saccharide alkyl ester compositions which meet the antimicrobial effectiveness test criteria set forth in USP 31 <51> in preventing growth of specified bacteria and fungi. | 03-18-2010 |
| 20100124567 | STABILIZING ALKYLGLYCOSIDE COMPOSITIONS AND METHODS THEREOF - The present invention relates to alkylglycoside-containing compositions and methods for increasing the stability, reducing the aggregation and immunogenicity, increasing the biological activity, and reducing or preventing fibrillar formation of a peptide, polypeptide, or variant thereof, for example parathyroid hormone (PTH) or PTH analogs, amylin, a monoclonal antibody, insulin, Peptide T or analog thereof, gastrin, gastrin releasing peptides, gastrin releasing peptide-like (GRP) proteins, epidermal growth factor or analog thereof. | 05-20-2010 |
| 20100160378 | COMPOSITIONS FOR DRUG ADMINISTRATION - The present invention provides compositions and methods and for increasing the bioavailability of therapeutic agents in a subject, as well as compositions and methods for providing migraine pain relief. The compositions include at least one alkyl glycoside and at least one therapeutic agent, such as a 5-HT receptor agonist, wherein the alkylglycoside has an alkyl chain length from about 10 to about 16 carbon atoms. | 06-24-2010 |
| 20100203014 | ZWITTERIONIC BUFFERED ACIDIC PEPTIDE AND PROTEIN FORMULATIONS - The present invention provides glycine buffered pharmaceutical compositions suitable for nasal administration and methods for nasal delivery of such compositions. The pharmaceutical compositions described herein include a therapeutically active peptide and/or protein admixed with an aqueous solution buffered with glycine and having a pH in the ranging from about 3.0 to 4.5. The compositions are formulated to maintain stability of the peptide for an extended period of time, but do not significantly change the normal pH of nasal mucosal secretions avoiding irritation and burning sensation in the nose upon administration. | 08-12-2010 |
| 20100209485 | STABILIZING ALKYLGLYCOSIDE COMPOSITIONS AND METHODS THEREOF - The present invention relates to alkylglycoside-containing compositions and methods for increasing the stability, reducing the aggregation and immunogenicity, increasing the biological activity, and reducing or preventing fibrillar formation of a peptide, polypeptide, or variant thereof, for example insulin and Peptide T or analog thereof. | 08-19-2010 |
| 20110005977 | DEVICE AND METHOD FOR SINGLE STREAM RECYCLING OF HAZARDOUS MATERIALS - The present invention provides devices and methods for facilitating the single stream recycling of toxic substance-containing products. A toxin impermeable container designed to enclose the product containing toxic substances incorporates graphic markings or radiofrequency tags to facilitate automated or manual sorting from single stream recycling processes, identification of the toxic component, identification of the person or entity recycling the toxic to allow verification and documentation of compliance with government regulations or reimbursement of a recycling deposit that may be associated with the particular product. | 01-13-2011 |
| 20110020435 | STABILIZING ALKYLGLYCOSIDE COMPOSITIONS AND METHODS THEREOF - The present invention relates to alkylglycoside-containing compositions and methods for increasing the stability, reducing the aggregation and immunogenicity, increasing the biological activity, and reducing or preventing fibrillar formation of insulin or an analog thereof. | 01-27-2011 |
| 20110046058 | COMPOSITIONS FOR ENTERAL ABSORPTION AND SUSTAINED ACTION OF LEPTIN-RELATED PEPTIDES USEFUL IN THE TREATMENT OF OBESITY AND LEPTIN-MODULATED DISEASE - The invention relates generally to enterally absorbed peptide compositions and more specifically to leptin-related peptide compositions, methods of administration, and methods of modulating the speed and sustained action of systemic absorption of such peptides useful in the treatment of obesity and other leptin modulated diseases. | 02-24-2011 |
| 20110129462 | INTRANASAL ADMINISTRATION OF ACTIVE AGENTS TO THE CENTRAL NERVOUS SYSTEM - Pharmaceutical compositions and methods for delivering a polypeptide to the central nervous system of a mammal via intranasal administration are provided. The polypeptide can be a catalytically active protein or an antibody, antibody fragment or antibody fragment fusion protein. The polypeptides are formulated with one or more specific agents. | 06-02-2011 |
