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Edward S. Boyden, Chestnut Hill US

Edward S. Boyden, Chestnut Hill, MA US

Patent application numberDescriptionPublished
20100152662Scalable Parallel Gene Therapy Injector Array - A scalable parallel injector array has a support structure for holding injector tubes in a spatial pattern in order to enable delivery of fluidic materials simultaneously to a group of specific target areas in the brain or a body part. Each injector is individually connectible at one end to a displacement-controlled pump and is designed at the other end to be inserted into the brain or body part. The injector tubes are connected to the pump by fluid-filled tubing. The spatial pattern is patient- and/or application-customizable, and the length of the injector tubes is customizable in order to more precisely reach individual target areas. A clamping device may be used to attach the injector array to a stereotaxic arm or other support structure. The action of the pump permits controlled simultaneous delivery of the fluidic materials to the target areas.06-17-2010
20100152880Systems, devices, and methods for making or administering frozen particles - Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one substrate.06-17-2010
20100163576Systems, devices, and methods for making or administering frozen particles - Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one substrate.07-01-2010
20100168900Systems, devices, and methods for making or administering frozen particles - Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one substrate.07-01-2010
20100174346System, devices, and methods including actively-controllable sterilizing excitation delivery implants - Systems, devices, methods, and compositions are described for providing an actively-controllable disinfecting implantable device configured to, for example, treat or prevent an infection in a biological subject.07-08-2010
20100185174Systems, devices, and methods for making or administering frozen particles - Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one substrate.07-22-2010
20100187728Systems, devices, and methods for making or administering frozen particles - Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one substrate.07-29-2010
20110165681Light-Activated Proton Pumps and Applications Thereof - In a method for adjusting the voltage potential or pH of, or cause proton release from, cells, subcellular regions, or extracellular regions, a gene encoding for a light-driven proton pump is incorporated into at least one target cell or region, the proton pump operating in response to a specific wavelength of light. Expression of the gene is caused by exposing the target cell or region to the specific wavelength of light in a manner designed to cause the voltage potential adjustment, pH adjustment, or proton release. The proton pump may be a microbial rhodopsin, in particular derived from the 07-07-2011