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Edward S. Boyden, Cambridge US

Edward S. Boyden, Cambridge, MA US

Patent application numberDescriptionPublished
20080199060Distortion compensated imaging - Certain aspects can relate to responsive to the at least some input compensating information, imaging the at least the portion of the individual in a manner to limit at least some distorting effects of the at least the portion of the at least one distorting feature associated with the at least the portion of the individual at least partially by modifying a non-optical electromagnetic output from an imaging modality as applied to the at least the portion of the at least one distorting feature associated with the at least the portion of the individual. Certain aspects can relate to creating at least one conformal absence of a non-optical electromagnetic output to limit distortion to an imaging of an at least a portion of an individual resulting at least partially from at least one distorting feature associated with the at least the portion of the individual.08-21-2008
20080201007Methods and systems for making a blood vessel sleeve - Methods, apparatuses, computer program products, devices and systems are described that include accepting one or more blood vessel sleeve dimensions based on blood vessel data from an individual; and making a rapid-prototyped blood vessel sleeve at least partly based on the one or more blood vessel sleeve dimensions.08-21-2008
20080207983Coded-sequence activation of surgical implants - Implants responsive to spatiotemporal signal sequences, and methods of operating implants by transmitting spatiotemporal signal sequences.08-28-2008
20080208010Coded-sequence activation of surgical implants - Implants responsive to spatiotemporal signal sequences, and methods of operating implants by transmitting spatiotemporal signal sequences.08-28-2008
20080216826Airway imaging system - Embodiments include a medical device, an apparatus, and a method. The medical device includes a tube portion shaped and sized for airway passage insertion and having at least one pathway therethrough; and a stylet of at least one shape-transforming material, configured for insertion in one of said at least one pathway; and at least one sensor carried by the tube portion and the stylet. The apparatus includes a stylet having a first end and a second end, at least a portion of the stylet including a shape-transforming material, the stylet being configured for insertion through an airway intubation structure having at least one pathway therethrough; and at least one sensor carried by the stylet in a proximity to the first end. The method includes capturing an image adjacent to an airway tube proximate to an airway passage; and actuating, in response to the image, at least one shape-transformation of the airway tube.09-11-2008
20080216840Imaging via the airway - Embodiments include a medical device, an apparatus, and a method. The medical device includes a tube portion shaped and sized for airway passage insertion and having at least one pathway therethrough; and a stylet of at least one shape-transforming material, configured for insertion in one of said at least one pathway; and at least one sensor carried by the tube portion and the stylet. The apparatus includes a stylet having a first end and a second end, at least a portion of the stylet including a shape-transforming material, the stylet being configured for insertion through an airway intubation structure having at least one pathway therethrough; and at least one sensor carried by the stylet in a proximity to the first end. The method includes capturing an image adjacent to an airway tube proximate to an airway passage; and actuating, in response to the image, at least one shape-transformation of the airway tube.09-11-2008
20080253511Scintillator aspects of compton scattered X-Ray visualization, imaging, or information providing - One aspect relates to visualizing, imaging, or providing information at least partially through at least some matter of an at least a portion of an individual, based at least in part on Compton scattering to at least partially form scattered X-rays, the Compton scattering occurring primarily in the at least some matter of the at least the portion of the individual, wherein the visualizing, imaging, or providing information is at least partially performed by converting the scattered X-rays into an at least one scintillated viewable and/or visible light that is detectable by a user. Another aspect relates to Compton scattered X-ray based visualizing, imaging, or providing information of an at least some matter of an at least a portion of an at least one individual to allow the at least one individual and/or an untrained assistant to at least partially visualize, image, or provide information into the at least some matter of the at least the portion of the individual based at least partially on Compton scattered X-rays.10-16-2008
20080253513Compton scattered X-ray visualization, imaging, or information provider in soft matter such as tissue, organs, or blood, and/or in hard matter such as bones or teeth - One aspect relates to visualizing, imaging, or providing information of an at least some tissue-based matter or bone-based matter of an at least a portion of an individual at least partially through at least one range of visualizing, imaging, or providing information depth to at least one prescribed visualizing, imaging, or providing information depth of the at least some tissue-based matter or bone-based matter of the at least the portion of the individual, at least partially dependent on an at least one applied characteristic of an at least one applied X-ray being applied to the at least some of the at least some tissue-based matter or bone-based matter of the at least the portion of the individual.10-16-2008
20080253520Compton scattered X-ray visualization, imaging, or information provider with scattering event locating - One aspect relates to determining a location of an at least one scattering event occurring within an at least some matter of at least a portion of an individual, wherein the determining the location of the the at least one scattering event is based at least in part on a combination of: a relative position and/or angle at which an at least one applied X-ray being applied to the at least some matter of the at least the portion of the individual, an applied energy level of the at least one applied X-ray being applied to the at least some matter of the at least the portion of the individual, a detected location of an at least one scattered X-ray resulting from scattering of the at least one applied X-ray scattering during the at least one scattering event, and a scattered energy level of the at least one scattered X-ray.10-16-2008
20080253521Compton scattered X-ray visualization, imaging, or information provider with time of flight computation - One aspect relates to locating an at least one scattering event at least partially within an at least some matter of an at least a portion of an individual at least partially by directing an at least one pulse-type applied X-ray at the at least some matter of the at least the portion of the individual to create an at least one corresponding pulse-type Compton scattered X-ray, wherein the locating the at least one scattering event is based at least in part on an at least one time of flight computation derived at least in part from a combination of an at least one applied duration and an at least one scattered duration, wherein the at least one applied duration corresponds to a time for the at least one pulse-type applied X-ray to reach the at least one scattering event within the at least some matter of the at least the portion of the individual, and further wherein the at least one scattered duration corresponds to a time for the at least one corresponding pulse-type Compton scattered X-ray to thereupon travel from the at least one scattering event within the at least some matter of the at least the portion of the individual to be detected.10-16-2008
20080253522Tool associated with compton scattered X-ray visualization, imaging, or information provider - One aspect relates to providing an at least one Compton scattered X-ray visualizing, imaging, or information providing operation relative to at least one visualizing, imaging, or information providing region within an at least some matter of an at least a portion of an individual; and providing a tool-based operation to at least the portion of the at least one visualizing, imaging, or information providing region within the at least some matter of the at least the portion of the individual based at least partially on the providing the at least one Compton scattered X-ray visualizing, imaging, or information providing operation relative to the at least the portion of the at least one visualizing, imaging, or information providing region.10-16-2008
20080253523Compton scattered X-ray depth visualization, imaging, or information provider - One aspect relates to at least a portion of at least one Compton scattered X-ray visualizer, imager, or information provider configured to receive an at least one Compton scattered X-ray that has scattered through a substantial scattering depth range to one or more substantial prescribed scattering depths within an at least one matter of an at least a portion of an individual based at least in part on a set of scattering characteristics, the set of scattering characteristics at least partially corresponding to the at least one matter of the least the portion of the individual; the at least the portion of the at least one Compton scattered X-ray visualizer, imager, or information provider being configured for providing an at least one Compton scattered X-ray visualization, imaging, or information providing through one or more visualization, imaging, or information providing depth ranges to one or more visualization, imaging, or information providing prescribed depths into the at least one matter of the least the portion of the individual.10-16-2008
20080253524Method and system for Compton scattered X-ray depth visualization, imaging, or information provider - One aspect relates to at least a portion of at least one Compton scattered X-ray visualizer, imager, or information provider configured to receive an at least one Compton scattered X-ray that has scattered through a substantial scattering depth range to one or more substantial prescribed scattering depths within an at least one matter of an at least a portion of an individual based at least in part on a set of scattering characteristics, the set of scattering characteristics at least partially corresponding to the at least one matter of the least the portion of the individual; the at least the portion of the at least one Compton scattered X-ray visualizer, imager, or information provider being configured for providing an at least one Compton scattered X-ray visualization, imaging, or information providing through one or more visualization, imaging, or information providing depth ranges to one or more visualization, imaging, or information providing prescribed depths into the at least one matter of the least the portion of the individual.10-16-2008
20080253525Compton scattered x-ray visualizing, imaging, or information providing of at least some dissimilar matter - One aspect relates to Compton Scattered X-ray visualizing, imaging, or providing information at least partially through an at least some matter of an at least a portion of an individual through an at least one prescribed visualizing, imaging, or information providing depth based at least partially on a density differentiation between the at least some matter of the at least the portion of the individual and at least some dissimilar matter of the at least the portion of the individual, wherein the Compton Scattered X-ray visualizing, imaging, or providing information is at least partially dependent on an at least one applied characteristic of an at least one applied X-ray being applied to the at least some matter of the at least the portion of the individual and the at least some matter of the at least the portion of the individual, and thereupon the at least one applied X-ray undergoes Compton Scattering within the at least some matter of the at least the portion of the individual in a manner that density differentiates the at least some matter of the at least the portion of the individual with respect to the at least some matter of the at least the portion of the individual.10-16-2008
20080253526Geometric compton scattered x-ray visualizing, imaging, or information providing - Certain aspects relate to determining a location that an at least one Compton Scattered X-ray event occurs within an at least some matter of at least a portion of an individual based at least in part on determining a relative angle at which an at least one applied X-ray is being applied to the at least some matter of the at least the portion of the individual, determining a relative position from which an at least one applied X-ray is being applied to the at least some matter of the at least the portion of the individual. Certain aspects can include determining a detected location at which at least one induced Compton scattered X-ray photon is detected following scattering at the at least one Compton Scattered X-ray event, and determining a received angle at which the at least one induced Compton scattered X-ray photon is received following scattering at the at least one Compton Scattered X-ray event.10-16-2008
20080253527Limiting compton scattered x-ray visualizing, imaging, or information providing at particular regions - One aspect relates to Compton X-ray scattering visualizing, imaging, or information providing within an at least some matter of an at least a portion of an individual to an at least one prescribed desired application regions within the at least some matter of the at least the portion of the individual based at least partially on an inducing of at least one induced Compton X-ray scattering photon within the at least some matter of the at least the portion of the individual responsive to an at least some applied X-rays being applied to the at least some matter of the at least the portion of the individual, wherein the Compton X-ray scattering visualizing, imaging, or information providing is limited to an at least one prescribed desired radiation protected region within the at least some matter of the at least the portion of the individual based at least partially on a limiting of an inducing of at least one induced Compton X-ray scattering photon within the at least one prescribed desired radiation protected region.10-16-2008
20080253528Low invasive technique using compton scattered x-ray visualizing, imaging, or information providing to differentiate at least some dissimilar matter - One aspect relates to ablating an at least some matter of an at least a portion of an individual within an at least one prescribed desired ablating region at least partially responsive to at least some Compton X-ray scattering visualizing, imaging, or information providing within the at least some matter of the at least the portion of the individual that is performed at least partially through a substantial depth through the at least some matter of the at least the portion of the individual. Certain aspects can include locating an at least one prescribed desired ablating region within the at least some matter of the at least the portion of the individual at least partially responsive to the Compton X-ray scattering visualizing, imaging, or information providing within the at least some matter of the at least the portion of the individual.10-16-2008
20080253529Ablating based at least partially on compton scattered x-ray visualizing, imaging, or information providing - Certain aspects relate to determining a desired ablating region within the at least some matter of the at least the portion of the individual at least partially in response to a Compton X-ray scattering visualizing, imaging, or information providing within the at least some matter of the at least the portion of the individual. Certain aspects can include ablating at least a portion of a desired ablating region within at least a portion of an at least some matter of an at least a portion of an individual based at least partially on a determining the desired ablating region within the at least some matter of the at least the portion of the individual responsive to the Compton X-ray scattering visualizing, imaging, or information providing within the at least some matter of the at least the portion of the individual.10-16-2008
20080253530Limiting ablation based at least partially on Compton scattered X-ray visualizing, imaging, or information providing - Certain aspects relate to locating an at least some matter of at least a portion of an individual within an at least one prescribed desired ablating region at least partially responsive to a Compton X-ray scattering visualizing, imaging, or information providing within the at least some matter of the at least the portion of the individual. Certain aspects relate to ablating the at least some matter of the at least the portion of the individual within the at least one prescribed desired ablating region at least partially responsive to a locating the at least some matter of the at least the portion of the individual within the at least one prescribed desired ablating region, in a manner that limits effects of the ablating to the at least some matter of the at least the portion of the individual at regions outside of the at least one prescribed desired ablating region based at least partially on the locating the at least one prescribed desired ablating region at least partially responsive to the locating the at least some matter of the at least the portion of the individual within the at least one prescribed desired ablating region.10-16-2008
20080253531Cauterizing based at least partially on Compton scattered x-ray visualizing, imaging, or information providing - Certain aspects relate to locating an at least one prescribed desired cauterizing region within an at least some matter of an at least a portion of an individual at least partially responsive to a Compton X-ray scattering visualizing, imaging, or information providing of the at least some matter of the at least the portion of the individual. Certain aspects relate to cauterizing the at least some matter of the at least the portion of the individual within the at least one prescribed desired ablating region at least partially responsive to the locating the at least one prescribed desired cauterizing region within the at least some matter of the at least the portion of the individual, at least partially response to the locating the at least one prescribed desired cauterizing region within the at least some matter of the at least the portion of the individual.10-16-2008
20080253627Compton scattered X-ray visualization, imaging, or information provider using image combining - One aspect relates to deriving at least one first visualization, image, or provided information via Compton scattering substantially within an at least some matter of an at least a portion of an individual at least partially as a result of directing an at least one first applied X-ray having an at least one first energy level towards the at least some matter of the at least the portion of the individual; deriving at least one second visualization, image, or provided information via Compton scattering substantially within the at least some matter of the at least the portion of the individual at least partially as a result of directing an at least one second applied X-ray having an at least one second energy level toward the at least some matter of the at least the portion of the individual; and deriving at least one combined visualization, combined image, or combined provided information at least partially by combining the at least one first visualization, image, or provided information with the at least one second visualization, image, or provided information.10-16-2008
20080253637Volumetric type compton scattered X-ray visualization, imaging, or information provider - One aspect relates to capturing one or more tomographic-type Compton scattering based visualizations, images, or provided information of an at least some matter of at least a portion of an individual based at least partially on Compton scattering of an at least one X-ray being applied to the at least some matter of the at least the portion of the individual. Another aspect relates to deriving an at least one material characteristic distribution function that substantially fits at least some data obtained at least partially by scattering of an at least one applied X-ray within at least some matter of at least a portion of an individual to form at least one Compton scattered X-ray.10-16-2008
20080262341Active blood vessel sleeve methods and systems - Methods, apparatuses, computer program products, devices and systems are described that include accepting one or more blood vessel sleeve dimensions based on blood vessel data from an individual; and making a rapid-prototyped blood vessel sleeve at least partly based on the one or more blood vessel sleeve dimensions.10-23-2008
20080262390Fiducials for placement of tissue closures - Fiducial markings are placed on a patient to identify surgical parameters such as locations for an incision or a surgical closure.10-23-2008
20080262524Systems and methods for closing of fascia - An opening in a fascia is closed by inserting a cannula through the fascia, and attaching a tissue anchor to the fascia from the exterior or through a side of the cannula.10-23-2008
20080262540Systems and methods for approximating surfaces - Tissue is approximated by adhering anchors to opposing sides of a wound and coupling the anchors together.10-23-2008
20080262543Systems and methods for approximating surfaces - Tissue is approximated by adhering anchors to opposing sides of a wound and coupling the anchors together.10-23-2008
20080283570Gentle touch surgical stapler - Embodiments include a surgical device and a method. An embodiment of the surgical instrument includes at least one grasping jaw, the at least one grasping jaw being adapted to deliver surgical staples by a force generated from a force generator mechanism that is contained within the at least one grasping jaw or is in a proximity to the at least one grasping jaw. Another embodiment includes at least one grasping jaw, at least one actuation mechanism adapted to deliver surgical fasteners, the actuation mechanism being located in a proximity to or contained within the at least one grasping jaw, the surgical fasteners containing at least one shape-transforming material, at least one sensor, at least one chemical tissue sealant and at least one cutter. A method includes: grasping a body organ/tissue with at least one grasping jaw, adjusting a configuration of the grasping in response to a signal or a datum or an image, and releasing a surgical staple/fastener in response to the signal, datum or image.11-20-2008
20080283571Sensing surgical fastener - Embodiments include a surgical device and a method. An embodiment of the surgical instrument includes at least one grasping jaw, the at least one grasping jaw being adapted to deliver surgical fasteners by a force generated from a force generator mechanism that is contained within the at least one grasping jaw or is in a proximity to the at least one grasping jaw. Another embodiment includes at least one grasping jaw, at least one actuation mechanism adapted to deliver surgical fasteners, the actuation mechanism being located in a proximity to or contained within the at least one grasping jaw, the surgical fasteners containing at least one shape-transforming material, at least one sensor, at least one chemical tissue sealant and at least one cutter. A method includes: grasping a body tissue with at least one grasping jaw, adjusting a configuration of the grasping in response to a signal or a datum or an image, and releasing a surgical staple or fastener in response to the signal, datum or image.11-20-2008
20080283572Surgical stapling instrument with chemical sealant - Embodiments include a surgical device and a method. An embodiment of the surgical instrument includes at least one grasping jaw, the at least one grasping jaw being adapted to deliver surgical staples by a force generated from a force generator mechanism that is contained within the at least one grasping jaw or is in a proximity to the at least one grasping jaw. Another embodiment includes at least one grasping jaw, at least one actuation mechanism adapted to deliver surgical staples, the actuation mechanism being located in a proximity to or contained within the at least one grasping jaw, the surgical staples containing at least one shape-transforming material, at least one sensor, at least one chemical tissue sealant and at least one cutter. A method includes: grasping a body tissue with at least one grasping jaw, adjusting a configuration of the grasping in response to a signal or a datum or an image, and releasing a surgical staple/fastener in response to the signal, datum or image.11-20-2008
20080283574Maneuverable surgical stapler - Embodiments include a surgical device and a method. An embodiment of the surgical instrument includes at least one grasping jaw, the at least one grasping jaw being adapted to deliver surgical staples by a force generated from a force generator mechanism that is contained within the at least one grasping jaw or is in a proximity to the at least one grasping jaw. Another embodiment includes at least one grasping jaw, at least one delivery mechanism adapted to deliver surgical fasteners, the delivery mechanism being located in a proximity to or contained within the at least one grasping jaw, the surgical fasteners containing at least one shape-transforming material, at least one sensor, at least one chemical tissue sealant and at least one cutter. A method includes: grasping a body tissue with at least one grasping jaw, adjusting a configuration of the grasping in response to a signal or a datum or an image, and releasing a surgical staple/fastener in response to the signal, datum or image.11-20-2008
20080283576Surgical fastening device with cutter - Embodiments include a surgical device and a method. An embodiment of the surgical fastening device includes at least one grasping jaw, the at least one grasping jaw being adapted to deliver surgical fasteners by a force generated from a force generator mechanism that is contained within the at least one grasping jaw or is in a proximity to the at least one grasping jaw. Another embodiment includes at least one grasping jaw, at least one actuation mechanism adapted to deliver surgical fasteners, the actuation mechanism being located in a proximity to or contained within the at least one grasping jaw, the surgical fasteners containing at least one shape-transforming material, at least one sensor, at least one chemical tissue sealant and at least one cutter. A method includes: grasping a body tissue with at least one grasping jaw, adjusting a configuration of the grasping in response to a signal or a datum or an image, and releasing a surgical staple/fastener in response to the signal, datum or image.11-20-2008
20080283577Steerable surgical stapler - Embodiments include a surgical device and a method. An embodiment of the surgical instrument includes at least one grasping jaw, the at least one grasping jaw being adapted to deliver surgical staples by a force generated from a force generator mechanism that is contained within the at least one grasping jaw or is in a proximity to the at least one grasping jaw. Another embodiment includes at least one grasping jaw, at least one delivery mechanism adapted to deliver surgical fasteners, the delivery mechanism being located in a proximity to or contained within the at least one grasping jaw, the surgical fasteners containing at least one shape-transforming material, at least one sensor, at least one chemical tissue sealant and at least one cutter. A method includes: grasping a body organ/tissue with at least one grasping jaw, adjusting a configuration of the grasping in response to a signal or a datum or an image, and releasing a surgical staple/fastener in response to the signal, datum or image.11-20-2008
20080287987Dispensing system for tissue sealants - The present invention discloses a medical device comprising a dispenser adapted to dispense a tissue sealant or one or more precursor compounds, the dispenser being operably coupled to a surgical stapler, which in turn is configured to deliver one or more surgical staples or fasteners in an area of bodily tissue approximation surface. Furthermore, the medical device comprises a dispenser adapted to dispense a tissue sealant or one or more precursor compounds thereof, the dispenser being operably coupled to a surgical cutter. Additionally or alternatively the medical; device can include a microactuation mechanism, whereby the dispenser dispenses the tissue sealant or one or more precursor compounds at a surgical cutting site or in a proximity thereof.11-20-2008
20080293050Gene analysis for determination of a treatment characteristic - An apparatus, device, methods, computer program product, and systems are described that determine at least one amino acid sequence alteration of an amino acid sequence of a disease associated polypeptide, relative to an amino acid sequence of a corresponding non-disease associated polypeptide, identify a sub-sequence in the amino acid sequence of the disease associated polypeptide in which the amino acid sequence alteration occurs, relate the sub-sequence in the amino acid sequence of the disease associated polypeptide to a corresponding sub-sequence of the amino acid sequence of the corresponding non-disease associated polypeptide, and determine a treatment characteristic, based on the relating.11-27-2008
20080306576Optical Cell Control Prosthetics - A prosthetic device for optical control of target cells comprises a set of light sources, hardware for guiding light to the target cells, supporting hardware that holds members of the set of light sources with respect to each other and the target cells, control circuitry for controlling the set of light sources, and power circuitry that provides power to the set of light sources and the control circuitry. The device may be wearable or implantable, and may be remotely powered or employ wireless communication. The supporting hardware may comprise implantable hypodermics or cannulas, or a plate or scaffold. The set of light sources may be assembled into an array.12-11-2008
20080319505Integrated Transcranial Current Stimulation and Electroencephalography Device - In an integrated transcranial current stimulation and electroencephalography device, data obtained by EEG electrodes is received, amplified, converted, and then processed by a microcontroller that extracts frequency information from the sampled data and produces signals in response to the extracted EEG data. These signals are converted to create a software-definable alternating voltage used to control a current-source that connects to stimulation electrodes. The device may further download recorded EEG data from the microcontroller to a computer for further analysis. Using the device, EEG signals are detected, then received, processed, and analyzed by a microcontroller to identify the patient state. Based on the patient state and the desired protocol, a type and amount of current stimulation to apply to the patient is determined and a control signal is sent from the microcontroller to the current source in order to trigger the transcranial current stimulation of the patient.12-25-2008
20090018384Portable, Modular Transcranial Magnetic Stimulation Device - A portable, modular transcranial magnetic stimulation device comprises a power supply unit, an energy storage unit, a charge recovery unit, a control unit, and at least one stimulation coil unit. The power supply unit generates specified voltages from a low voltage supply. The energy storage unit stores voltage received from the power supply unit until it is needed to generate a stimulation pulse and preferably includes discharge circuitry for discharging the stored voltage. The stimulation coil unit stores energy received from the energy storage unit as a strong current for application of magnetic stimulation to a patient. The charge recovery unit converts energy stored as current in the stimulation coil unit back to energy stored as voltage in the energy storage unit. The control unit controls the operation of the power supply unit, the energy storage unit, and the charge recovery unit. Biphasic, multiphasic, and monophasic stimulators may be implemented.01-15-2009
20090024018Anatomical imaging system - Embodiments include a medical device, an apparatus, and a method. The medical device includes a tube portion shaped and sized for airway passage insertion and having at least one pathway therethrough; and a stylet of at least one shape-transforming material, configured for insertion in one of said at least one pathway; and at least one sensor carried by the tube portion and the stylet. The apparatus includes a stylet having a first end and a second end, at least a portion of the stylet including a shape-transforming material, the stylet being configured for insertion through an airway intubation structure having at least one pathway therethrough; and at least one sensor carried by the stylet in a proximity to the first end. The method includes capturing an image adjacent to an airway tube proximate to an airway passage; and actuating, in response to the image, at least one shape-transformation of the airway tube.01-22-2009
20090024152Custom-fitted blood vessel sleeve - Methods, apparatuses, computer program products, devices and/or systems are described that include a blood vessel sleeve that is custom-fitted for the outside of a blood vessel at least partly based on anatomical blood vessel data from an individual.01-22-2009
20090076840Wireless ICU - A method may include receiving information from two or more wireless sensors and identifying patient identification information included in the information.03-19-2009
20090084951Scintillator aspects for X-Ray fluorescence visualizer, imager, or information provider - One aspect relates to optically detecting an at least one scintillated viewable and/or visible photon that has been converted from the at least one induced X-ray fluorescing photon. The aspect can also relate to optically detecting an at least one scintillated viewable and/or visible photon that has been converted from the at least one induced X-ray fluorescing photon.04-02-2009
20090086892Proximity-based X-ray fluorescence visualizer, imager, or information provider - One aspect relates to detecting at least one induced X-ray fluorescing photon fluoresced from substantially within an at least some matter of an at least a portion of an at least one individual at least partially as a result of receiving at least one induced X-ray fluorescing photon generated at least partially within at least one X-ray fluorescence event within the at least some matter of the at least the portion of the at least one individual which has been generated responsive to an at least some input energy resulting from a single input energy event, wherein the at least one induced X-ray fluorescing photon that has passed through the at least some matter of the at least the portion of the at least one individual is at a level to substantially limit interference between the at least one induced X-ray fluorescing photon with an at least one other induced X-ray fluorescing photon that travel for distances greater than a prescribed limit through the at least some matter of the at least the portion of the at least one individual, wherein the at least one other induced X-ray fluorescing photon attenuates by a prescribed percentage after passing through the prescribed distance through the at least some matter of the at least the portion of the at least one individual.04-02-2009
20090086893Combining X-Ray fluorescence visualizer, imager, or information provider - One aspect relates to deriving at least one first X-ray fluorescence visualization, image, or provided information substantially within an at least some matter of an at least a portion of an at least one individual at least partially as a result of directing an at least one first applied high energy photon and/or particle having an at least one first input energy towards the at least some matter of the at least the portion of the at least one individual. The aspect comprises deriving at least one second X-ray fluorescence visualization, image, or provided information substantially within the at least some matter of the at least the portion of the at least one individual at least partially as a result of directing an at least one second applied high energy photon and/or particle having an at least one second input energy toward the at least some matter of the at least the portion of the at least one individual. The aspect comprises deriving an at least one combined X-ray fluorescence visualization, combined image, or combined provided information at least partially by combining the at least one first X-ray fluorescence visualization, image, or provided information with the at least one second X-ray fluorescence visualization, image, or provided information.04-02-2009
20090086894Time of flight aspects for X-Ray fluorescence visualizer, imager, or information provider - One aspect can relate to determining a total time of flight that indicates an at least one applied duration and an at least one induced duration, wherein the at least one applied duration describes the time for an at least some pulse-type input energy to be applied from a transmission location to an at least one X-ray fluorescing event in the at least some matter of the at least the portion of the at least one individual, and wherein the at least one induced duration describes the time for an at least one induced X-ray fluorescing photon, to travel from the at least one X-ray fluorescing event in the at least some matter of the at least the portion of the at least one individual to a location where the at least one induced X-ray fluorescing photon is received at least partially by a detecting the at least one induced X-ray fluorescing photon. The aspect can relate to determining a location information of the at least one X-ray fluorescing event in the at least some matter of the at least the portion of the at least one individual based at least partially on the total time of flight.04-02-2009
20090086895Geometric X-Ray fluorescence visualizer, imager, or information provider - One aspect relates to determining a location of an at least one X-ray fluorescing event occurring within an at least some matter of at least a portion of an individual, wherein the determining the location of the at least one X-ray fluorescing event is based at least in part on determining a relative angle at which an at least one applied high energy photon and/or particle is being applied to the at least some matter of the at least the portion of the individual, a relative position from which an at least one applied high energy photon and/or particle is being applied to the at least some matter of the at least the portion of the individual, a detected location of an at least one induced fluorescing X-ray photon fluoresced during the at least one X-ray fluorescing event, and a received angle at which the at least one induced fluorescing X-ray photon is received.04-02-2009
20090086896Tool based X-ray fluorescence visualizing, imaging, or information providing - Certain embodiments of one aspect relates to inducing at least one induced X-ray fluorescing photon within an at least some matter of an at least a portion of an at least one individual responsive to an at least some input energy being applied to the at least some matter of the least the portion of the at least one individual. The aspect can include X-ray fluorescence visualizing, imaging, or information providing within the at least some matter of the least the portion of the at least one individual at least partially in response to the inducing at least one induced X-ray fluorescing photon within the at least some matter of the least the portion of the at least one individual. Certain embodiments of the aspect can include providing a substantial real time tool-based operation to the at least some matter of the least the portion of the at least one individual at least partially relying on the X-ray fluorescence visualizing, imaging, or information providing within the at least some matter of the least the portion of the at least one individual.04-02-2009
20090086899Repositioning X-ray fluorescence visualizer, imager, or information provider - One aspect can relate to performing a first X-ray fluorescence visualizing, imaging, or information providing within a first field of view in an at least some matter of an at least a portion of an at least one individual based on at least one induced fluorescing X-ray photon. The aspect can include operationally repositioning the first X-ray fluorescence visualizing, imaging, or information providing to X-ray fluorescence visualize, image, or information provide from within the first field of view to within a second field of view. The aspect can include performing a second X-ray fluorescence visualizing, imaging, or information providing within the second field of view within the at least some matter of the at least the portion of the at least one individual.04-02-2009
20090086900Portable aspects for x-ray fluorescence visualizer, imager, or information provider - One aspect relates to inducing at least one induced X-ray fluorescing photon at a X-ray fluorescence event within an at least some matter of an at least a portion of an at least one individual responsive to an at least some input energy being applied to the at least some matter of the at least the portion of the at least one individual. The aspect can include detecting the at least one induced X-ray fluorescing photon, wherein the inducing at least one induced X-ray fluorescing photon and the detecting the at least one induced X-ray fluorescing photon is configured to be transported portably as a self-contained and self-powered unit.04-02-2009
20090086901X-ray fluorescence visualizing, imaging, or information providing of chemicals, compounds, or biological materials - One aspect can relate to detecting a presence of an at least one chemical, compound, or biological material contained in an at least some matter of an at least a portion of an at least one individual based at least partially on addition of an at least one chemical identifying additive to the at least some matter of the at least the portion of the at least one individual based at least partially on a generation of an at least one induced X-ray fluorescing photon within the at least one chemical identifying additive responsive to a single input energy event in which an at least some input energy is being applied proximal to the at least one chemical, compound, or biological material contained in the at least some matter of the at least the portion of the at least one individual.04-02-2009
20090086902Personal transportable X-ray fluorescence visualizing, imaging, or information providing - One aspect relates to inducing at least one induced X-ray fluorescing photon at a X-ray fluorescence event within an at least some matter of an at least a portion of an at least one individual responsive to an at least some input energy being applied to the at least some matter of the at least the portion of the at least one individual. The aspect can relate to detecting the at least one induced X-ray fluorescing photon, wherein the inducing at least one induced X-ray fluorescing photon and the detecting the at least one induced X-ray fluorescing photon is configured to be performed at least partially with at least one device which is configured to be transported portably by a person.04-02-2009
20090086903Selective elemental color providing for X-ray fluorescence visualization, imaging, or information providing - One aspect relates to selective X-ray fluorescence visualization, imaging, or information providing of an at least some matter of an at least a portion of an individual that at least partially indicates an at least one differentiatable element composition of the at least some matter of the at least the portion of the individual, wherein the selective X-ray fluorescence visualization, imaging, or information providing selectively displays a first at least one differentiatable element composition of the at least some matter of the at least the portion of the individual at least partially responsive to a first single input energy event based at least partially on an at least some first input energy being applied to the at least some matter of the at least the portion of the individual, and the selective X-ray fluorescence visualization, imaging, or information providing selectively displays a second at least one differentiatable element composition of the at least some matter of the at least the portion of the individual that is interpretable distinctly from the first at least one differentiatable element composition.04-02-2009
20090086904X-Ray fluorescence visualizing, imaging, or information providing of chemicals, compounds, or biological materials - One aspect can relate to detecting a prescence of an at least one chemical, compound, or biological material contained in an at least some matter of an at least a portion of an at least one individual based at least partially on addition of an at least one chemical identifying additive to the at least some matter of the at least the portion of the at least one individual based at least partially on a generation of an at least one induced X-ray fluorescing photon within the at least one chemical identifying additive responsive to a single input energy event in which an at least some input energy is being applied proximal to the at least one chemical, compound, or biological material contained in the at least some matter of the at least the portion of the at least one individual.04-02-2009
20090086905X-ray fluorescence visualizer, imager, or information provider - One aspect relates to inducing at least one induced X-ray fluorescing photon within an at least some matter of an at least a portion of an at least one individual responsive to a substantial single input energy event based at least partially on an at least some input energy being applied to the at least some matter of the at least the portion of the at least one individual; and detecting the at least one induced X-ray fluorescing photon; and X-ray fluorescence visualizing, imaging, or information providing within the at least some matter of the at least the portion of the at least one individual responsive to the detecting the at least one induced X-ray fluorescing photon.04-02-2009
20090101153Method of facilitated airway intubation - Embodiments include a medical device, an apparatus, and a method. The medical device includes a tube portion shaped and sized for airway passage insertion and having at least one pathway therethrough; and a stylet of at least one shape-transforming material, configured for insertion in one of said at least one pathway; and at least one sensor carried by the tube portion and the stylet. The apparatus includes a stylet having a first end and a second end, at least a portion of the stylet including a shape-transforming material, the stylet being configured for insertion through an airway intubation structure having at least one pathway therethrough; and at least one sensor carried by the stylet in a proximity to the first end. The method includes capturing an image adjacent to an endotracheal tube proximate to an airway passage; and actuating, in response to the image, at least one shape-transformation of the endotracheal tube.04-23-2009
20090101838Ionizing-radiation-responsive compositions, methods, and systems - A method, composition and system respond to ionizing radiation to adjust biological activity. In some approaches the ionizing radiation is X-ray or extreme ultraviolet radiation that produces luminescent responses that induce biologically active responses.04-23-2009
20090101840Ionizing-radiation-responsive compositions, methods, and systems - A method composition and system respond to ionizing radiation to adjust biological activity. In some approaches the ionizing radiation is X-ray or extreme ultraviolet radiation that produces luminescent responses that induce biologically active responses.04-23-2009
20090101841Ionizing-radiation-responsive compositions, methods, and systems - A method composition and system respond to ionizing, radiation to adjust biological activity. In some approaches the ionizing radiation is X-ray or extreme ultraviolet radiation that produces luminescent responses that induce biologically active responses.04-23-2009
20090101846Ionizing-radiation-responsive compositions, methods, and systems - A method, composition and system respond to ionizing radiation to adjust biological activity. In some approaches the ionizing radiation is X-ray or extreme ultraviolet radiation that produces luminescent responses that induce biologically active responses.04-23-2009
20090101875Ionizing-radiation-responsive compositions, methods, and systems - A method, composition and system respond to ionizing radiation to adjust biological activity. In some approaches the ionizing radiation is X-ray or extreme ultraviolet radiation that produces luminescent responses that induce biologically active responses.04-23-2009
20090104113Ionizing-radiation-responsive compositions, methods, and systems - A method, composition and system respond to ionizing, radiation to adjust biological activity. In some approaches the ionizing radiation is X-ray or extreme ultraviolet radiation that produces luminescent responses that induce biologically active responses.04-23-2009
20090104179Ionizing-radiation-responsive compositions, methods, and systems - A method, composition and system respond to ionizing radiation to adjust biological activity. In some approaches the ionizing radiation is X-ray or extreme ultraviolet radiation that produces luminescent responses that induce biologically active responses.04-23-2009
20090104250Medical or veterinary digestive tract utilization systems and methods - Systems and methods are described for implementing or deploying medical or veterinary utility modules (a) operable for mooring at least partly within a digestive tract, (b) small enough to pass through the tract per vias naturales and including a wireless-control component, (c) having one or more attachment protrusions positionable adjacent to a mucous membrane, (d) configured to facilitate redundant modes of attachment, (e) facilitating a “primary” material supply deployable within a stomach for an extended and/or controllable period, (f) moored by one or more adaptable extender modules supported by a subject's head or neck, and/or (g) configured to facilitate supporting at least a sensor within a subject's body lumen for up to a day or more.04-23-2009
20090105531Disintegrating digestive tract interaction system - Systems and methods are described for configuring several modules each individually small enough to pass through a digestive tract; and a tether or other means for releasably configuring at least the several modules in a group. Such a tether may (directly or indirectly) couple some of the modules via at least a gap in another module from which the tether may slip free, in some embodiments. Such methods may include modes of administering a medication or otherwise taking an action in response to the one or more phenomena.04-23-2009
20090105561Medical or veterinary digestive tract utilization systems and methods - Systems and methods are described for implementing or deploying medical or veterinary utility modules (a) operable for mooring at least partly within a digestive tract, (b) small enough to pass through the tract per vias naturales and including a wireless-control component, (c) having one or more attachment protrusions positionable adjacent to a mucous membrane, (d) configured to facilitate redundant modes of attachment, (e) facilitating a “primary” material supply deployable within a stomach for an extended and/or controllable period, (f) moored by one or more adaptable extender modules supported by a subject's head or neck, and/or (g) configured to facilitate supporting at least a sensor within a subject's body lumen for up to a day or more.04-23-2009
20090105694Medical or veterinary digestive tract utilization systems and methods - Systems and methods are described for implementing or deploying medical or veterinary utility modules (a) operable for mooring at least partly within a digestive tract, (b) small enough to pass through the tract per vias naturales and including a wireless-control component, (c) having one or more attachment protrusions positionable adjacent to a mucous membrane, (d) configured to facilitate redundant modes of attachment, (e) facilitating a “primary” material supply deployable within a stomach for an extended and/or controllable period, (f) moored by one or more adaptable extender modules supported by a subject's head or neck, and/or (g) configured to facilitate supporting at least a sensor within a subject's body lumen for up to a day or more.04-23-2009
20090110714Medical or veterinary digestive tract utilization systems and methods - Systems and methods are described for implementing or deploying medical or veterinary utility modules comprising a first module operable in a digestive or respiratory tract to engage a second module, optionally by a magnetic field. Alternatively or additionally, systems may be operable to remain in situ and also operable to permit a therapeutic material dispensation. In some contexts, for example, systems or methods may dispense a therapeutic material via a subject's throat or elsewhere in the digestive or respiratory tract.04-30-2009
20090112190Medical or veterinary digestive tract utilization systems and methods - Systems and methods are described for implementing or deploying medical or veterinary utility modules comprising a first module operable in a digestive or respiratory tract to engage a second module, optionally by a magnetic field. Alternatively or additionally, systems may be operable to remain in situ and also operable to permit a therapeutic material dispensation. In some contexts, for example, systems or methods may dispense a therapeutic material via a subject's throat or elsewhere in the digestive or respiratory tract.04-30-2009
20090112191Medical or veterinary digestive tract utilization systems and methods - Systems and methods are described for implementing or deploying medical or veterinary utility modules comprising a first module operable in a digestive or respiratory tract to engage a second module, optionally by a magnetic field. Alternatively or additionally, systems may be operable to remain in situ and also operable to permit a therapeutic material dispensation. In some contexts, for example, systems or methods may dispense a therapeutic material via a subject's throat or elsewhere in the digestive or respiratory tract.04-30-2009
20090112243Surgical cutter with dispensing system for tissue sealants - The present invention discloses a medical device comprising a dispenser adapted to dispense a tissue sealant or one or more precursor compounds, the dispenser being operably coupled to a surgical stapler, which in turn is configured to deliver one or more surgical staples or fasteners in an area of bodily tissue approximation surface. Furthermore, the medical device comprises a dispenser adapted to dispense a tissue sealant or one or more precursor compounds thereof, the dispenser being operably coupled to a surgical cutter. Additionally or alternatively the medical; device can include an actuation mechanism, whereby the dispenser dispenses the tissue sealant or one or more precursor compounds at a surgical cutting site or in a proximity thereof.04-30-2009
20090112256Suturing device with tissue sealant dispenser - The present invention discloses a medical device comprising a dispenser adapted to dispense a tissue sealant or one or more precursor compounds, the dispenser being operably coupled to a surgical suturing device, which in turn is configured to deliver one or more surgical sutures or fasteners in an area of bodily tissue approximation surface. Furthermore, the medical device comprises a dispenser adapted to dispense a tissue sealant or one or more precursor compounds thereof, the dispenser being operably coupled to a surgical cutter. Additionally or alternatively the medical; device can include a microactuation mechanism, whereby the dispenser dispenses the tissue sealant or one or more precursor compounds at a surgical cutting site or in a proximity thereof.04-30-2009
20090130017Targeted short-lived drug delivery - An aspect of the disclosure includes a system for delivering therapeutic agents. In an embodiment, the system includes an implantable medical device comprising at least one reservoir that holds at least one therapeutic agent. Additionally the device includes a delivery mechanism that provides non-systemic in vivo delivery of the at least one therapeutic agent to a local area of an animal in a therapeutically-effective concentration, wherein the therapeutically-effective concentration is in excess of a concentration that would produce a toxic effect when administered systemically to the animal. Furthermore, the at least one therapeutic agent has short half-life. A further aspect of the disclosure includes a method of delivering a therapeutic agent in vivo at non-systemic high doses to a localized area of an animal.05-21-2009
20090136099Image guided surgery with dynamic image reconstruction - A method may include processing two or more fiducials included in a three-dimensional medical image and included in a current image to generate two or more transform coefficients of a transform, and applying the transform to the three-dimensional medical image to form a present image.05-28-2009
20090137866Medical or veterinary digestive tract utilization systems and methods - Systems and methods are described for implementing or deploying medical or veterinary utility modules (a) operable for mooring at least partly within a digestive tract, (b) small enough to pass through the tract per vias naturales and including a wireless-control component, (c) having one or more attachment protrusions positionable adjacent to a mucous membrane, (d) configured to facilitate redundant modes of attachment, (e) facilitating a “primary” material supply deployable within a stomach for an extended and/or controllable period, (f) moored by one or more adaptable extender modules supported by a subject's head or neck, and/or (g) configured to facilitate supporting at least a sensor within a subject's body lumen for up to a day or more.05-28-2009
20090142413Targeted short-lived drug delivery - An aspect of the disclosure includes a system for delivering therapeutic agents. In an embodiment, the system includes an implantable medical device comprising at least one reservoir that holds at least one therapeutic agent. Additionally the device includes a delivery mechanism that provides non-systemic in vivo delivery of the at least one therapeutic agent to a local area of an animal in a therapeutically-effective concentration, wherein the therapeutically-effective concentration is in excess of a concentration that would produce a toxic effect when administered systemically to the animal. Furthermore, the at least one therapeutic agent has short half-life. A further aspect of the disclosure includes a method of delivering a therapeutic agent in vivo at non-systemic high doses to a localized area of an animal.06-04-2009
20090143816Grasper with surgical sealant dispenser - The present disclosure is directed to a medical device comprising a dispenser adapted to dispense a tissue sealant or one or more precursor compounds, the dispenser being operably coupled to a grasper. Furthermore, the medical device comprises a dispenser adapted to dispense a tissue sealant or one or more precursor compounds thereof, the dispenser being operably coupled to a surgical cutter. Additionally or alternatively the medical device can include an actuation mechanism, whereby the dispenser dispenses the tissue sealant or one or more precursor compounds at a surgical cutting site or in a proximity thereof.06-04-2009
20090157059Surgical instrument navigation system - The disclosure pertains to a surgical system. In an embodiment, the system comprises one or more sensors operably responsive to physical boundary limitations of an operating field. Furthermore, the one or more sensors provide information regarding the physical boundary limitations of the operating field. In another embodiment, the system comprises a surgical instrument that is configured to respond to the information by either activation or inactivation. In another aspect the disclosure includes generating an anatomical image or anatomic positional reference data from one or more anatomical objects. Additionally, the method includes creating haptic feedback signals based at least partly on the anatomical image or anatomic positional reference data, and determining a position or orientation of a surgical instrument. Furthermore the method includes activating or inactivating the surgical instrument based at least partly on the haptic feedback signals.06-18-2009
20090171263System, devices, and methods including actively-controllable superoxide water generating systems - Systems, devices, methods, and compositions are described for providing an actively-controllable disinfecting implantable device configured to, for example, treat or prevent an infection in a biological subject.07-02-2009
20090177139System, devices, and methods including actively-controllable electromagnetic energy-emitting delivery systems and energy-activateable disinfecting agents - Systems, devices, methods, and compositions are described for providing an actively-controllable disinfecting implantable device configured to, for example, treat or prevent an infection in a biological subject.07-09-2009
20090177254System, devices, and methods including actively-controllable electrostatic and electromagnetic sterilizing excitation delivery system - Systems, devices, methods, and compositions are described for providing an actively-controllable disinfecting implantable device configured to, for example, treat or prevent an infection in a biological subject.07-09-2009
20090192449Adaptive dispensation in a digestive tract - Systems and methods are described for implementing a bioactive material selection from within a digestive tract and transmitting a wireless signal indicating at least the bioactive material selection from within the digestive tract.07-30-2009
20090210039Prosthetic system for therapeutic optical activation and silencing of genetically-targeted neurons - An optical prosthesis that permits control of neural circuits comprises a probe having a set of light sources, drive circuit connections connected to each light source, a housing surrounding the light sources and drive circuit connections, and drive circuitry for driving and controlling the probe. The drive circuit connections and drive circuitry may optionally provide for wireless communication. The light sources may be light-emitting diodes, lasers, or other suitable sources. The device may optionally include sensors for monitoring the target cells. The present invention is also a multi-dimensional array of probes, each probe having a set of light sources, drive circuit connections connected to each light source, a housing surrounding the light sources and the drive circuit connections, drive circuitry for driving and controlling the probes, and supporting hardware that holds the probes in position with respect to each other and the target cells.08-20-2009
20090281412System, devices, and methods for detecting occlusions in a biological subject - Systems, devices, and methods are described for detecting an embolus, thrombus, or a deep vein thrombus in a biological subject.11-12-2009
20090281413Systems, devices, and methods for detecting occlusions in a biological subject - Systems, devices, and methods are described for detecting an embolus, thrombus, or a deep vein thrombus in a biological subject.11-12-2009
20090287076System, devices, and methods for detecting occlusions in a biological subject - Systems, devices, and methods are described for detecting an embolus, thrombus, or a deep vein thrombus in a biological subject.11-19-2009
20090292195System, devices, and methods for detecting occlusions in a biological subject including spectral learning - Systems, devices, and methods are described for detecting an embolus, thrombus, or a deep vein thrombus in a biological subject.11-26-2009
20090296887Aspects of compton scattered X-RAY visualization, imaging, or information providing - One aspect relates to visualizing, imaging, or providing information at least partially through at least some matter of an at least a portion of an individual, based at least in part on Compton scattering to at least partially form scattered X-rays, the Compton scattering occurring primarily in the at least some matter of the at least the portion of the individual, wherein the visualizing, imaging, or providing information is at least partially performed by converting the scattered X-rays into an at least one scintillated viewable and/or visible light that is detectable by a user. Another aspect relates to Compton scattered X-ray based visualizing, imaging, or providing information of an at least some matter of an at least a portion of an at least one individual to allow the at least one individual and/or an untrained assistant to at least partially visualize, image, or provide information into the at least some matter of the at least the portion of the individual based at least partially on Compton scattered X-rays.12-03-2009
20090311269Methods for collecting and detecting oligonucleotides - Methods, pharmaceutical compositions, and kits are provided which includes accurately sampling a RNA from a tissue of an animal and analyzing RNA in the tissue of the animal as an indicator of physiological state, infectious disease, neoplastic disease, autoimmune disease, inflammatory disease, cardiovascular disease, atherosclerotic disease, or neurological disease in the animal. A method is provided which includes administering at least one compound to an animal wherein the at least one compound is configured to prevent the cleavage of at least one tissue RNA by a ribonuclease. The method further includes collecting a sample of at least a portion of tissue from the animal.12-17-2009
20090311270Methods, compositions, and kits for collecting and detecting oligonucleotides - Methods, pharmaceutical compositions, and kits are provided which includes accurately sampling a RNA from a tissue of an animal and analyzing RNA in the tissue of the animal as an indicator of physiological state, infectious disease, neoplastic disease, autoimmune disease, inflammatory disease, cardiovascular disease, atherosclerotic disease, or neurological disease in the animal. A method is provided which includes administering at least one compound to an animal wherein the at least one compound is configured to prevent the cleavage of at least one tissue RNA by a ribonuclease. The method further includes collecting a sample of at least a portion of tissue from the animal.12-17-2009
20090311665Methods, compositions, and kits for collecting and detecting oligonucleotides - Methods, pharmaceutical compositions, and kits are provided which includes accurately sampling a RNA from a tissue of an animal and analyzing RNA in the tissue of the animal as an indicator of physiological state, infectious disease, neoplastic disease, autoimmune disease, inflammatory disease, cardiovascular disease, atherosclerotic disease, or neurological disease in the animal. A method is provided which includes administering at least one compound to an animal wherein the at least one compound is configured to prevent the cleavage of at least one tissue RNA by a ribonuclease. The method further includes collecting a sample of at least a portion of tissue from the animal.12-17-2009
20090318802System, devices, and methods for detecting occlusions in a biological subject - Systems, devices, and methods are described for detecting an embolus, thrombus, or a deep vein thrombus in a biological subject.12-24-2009
20090326443Preparatory dispensation systems and methods - Methods and systems are described for receiving wireless control signal content into a module containing one or more active ingredients and causing one or more dispensations from the module according to a programmatic dispensation profile partly dependent on the wireless control signal content and partly dependent on an attribute of the module; or for obtaining data indicating a future event time intended by an individual, and causing a bioactive material administration to the individual in response to the data to occur about or before the future event time.12-31-2009
20090326516Preparatory dispensation systems and methods - Methods and systems are described for receiving wireless control signal content into a module containing one or more active ingredients and causing one or more dispensations from the module according to a programmatic dispensation profile partly dependent on the wireless control signal content and partly dependent on an attribute of the module; or for obtaining data indicating a future event time intended by an individual, and causing a bioactive material administration to the individual in response to the data to occur about or before the future event time.12-31-2009
20100052892Health-related signaling via wearable items - Systems and methods are described for configuring and using displays, speakers, or other output devices positioned by an article of clothing or other such structure wearable by a healthcare recipient, for example, in a clinic or residential care facility.03-04-2010
20100052897Health-related signaling via wearable items - Systems and methods are described for configuring and using displays, speakers, or other output devices positioned by an article of clothing or other such structure wearable by a healthcare recipient, for example, in a clinic or residential care facility.03-04-2010
20100052898Health-related signaling via wearable items - Systems and methods are described for configuring and using displays, speakers, or other output devices positioned by an article of clothing or other such structure wearable by a healthcare recipient, for example, in a clinic or residential care facility.03-04-2010
20100052915Health-related signaling via wearable items - Systems and methods are described for configuring and using displays, speakers, or other output devices positioned by an article of clothing or other such structure wearable by a healthcare recipient, for example, in a clinic or residential care facility.03-04-2010
20100056873Health-related signaling via wearable items - Systems and methods are described for configuring and using displays, speakers, or other output devices positioned by an article of clothing or other such structure wearable by a healthcare recipient, for example, in a clinic or residential care facility.03-04-2010
20100062428Methods for collecting and detecting oligonucleotides - Methods, pharmaceutical compositions, and kits are provided which includes accurately sampling a RNA from a tissue of an animal and analyzing RNA in the tissue of the animal as an indicator of physiological state, infectious disease, neoplastic disease, autoimmune disease, inflammatory disease, cardiovascular disease, atherosclerotic disease, or neurological disease in the animal. A method is provided which includes administering at least one compound to an animal wherein the at least one compound is configured to prevent the cleavage of at least one tissue RNA by a ribonuclease. The method further includes collecting a sample of at least a portion of tissue from the animal.03-11-2010
20100068152Ex vivo modifiable particle or polymeric based final dosage form - Provided embodiments include a final dosage form, an article of manufacture, and method. A final dosage form for administering a medicament to an animal is provided. The final dosage form includes the medicament, and a particle or polymeric material. The particle or polymeric material carries the medicament and is configured in a medicament-retention state. In medicament-retention state, the medicament is substantially not bioavailable to the animal if the final dosage form is administered to the animal. The particle or polymeric material is modifiable ex vivo by an exposure to a stimulus to a medicament-release state. In the medicament-release state, the medicament is substantially bioavailable to the animal if the final dosage form is administered to the animal.03-18-2010
20100068153Ex vivo activatable final dosage form - Provided embodiments include a final dosage form, an article of manufacture, and method. A final dosage form for administering a medicament to an animal is provided. The final dosage form includes an outer layer, the medicament, and a release element. The release element configured in a medicament-holding state and modifiable ex vivo to a medicament-discharge state by an exposure to a stimulus. In an embodiment, the final dosage form includes a chamber substantially within the outer layer and carrying the medicament. In an embodiment, the final dosage form includes an indicator element configured to indicate an exposure of the release element to the stimulus.03-18-2010
20100068233Modifiable dosage form - Provided embodiments include a final dosage form, an article of manufacture, and method. A final dosage form for delivering a medicament to an animal is provided. The final dosage form includes an outer layer. The final dosage form also includes a release element configured in a first medicament-release state and modifiable to a second medicament-release state upon an ex vivo exposure to a stimulus. The final dosage form further includes a chamber at least substantially within the outer layer and configured to carry the medicament. The final dosage form includes the medicament. The final dosage form may include an indicator element configured to indicate an exposure of the release element to the stimulus.03-18-2010
20100068235Individualizable dosage form - Provided embodiments include a final dosage form, an article of manufacture, and a method. A final dosage form for delivering a medicament to an animal is provided. The final dosage form includes an outer layer. The final dosage form also includes a release element configured in a first medicament-release state and modifiable to a second medicament-release state upon an ex vivo exposure to a stimulus. The final dosage form further includes a chamber at least substantially within the outer layer and configured to carry the medicament. The final dosage form further includes a containment element configured to retain the medicament within the final dosage form until the dosage form is administered to the animal. The final dosage form includes the medicament. The final dosage form may include an indicator element configured to indicate an exposure of the release element to the stimulus.03-18-2010
20100068254Modifying a medicament availability state of a final dosage form - Provided embodiments include a final dosage form, an article of manufacture, and method. A method of modifying a medicament availability state of a final dosage form is provided. The method includes initiating an exposure of a particle or polymeric material of the final dosage form to a stimulus. The initiated stimulus is selected to transform the particle or polymeric material from a medicament-retention state to a medicament-release state.03-18-2010
20100068256Ex vivo modifiable medicament release-substance - A described final dosage form includes a substance carrying a medicament in a first medicament-release state having a first bioavailability. The substance is modifiable ex vivo by an exposure to a first stimulus to carry the medicament in a second medicament-release state having a second bioavailability. The substance is modifiable ex vivo by an exposure to a second stimulus to carry the medicament in a third medicament-release state having a third bioavailability. The final dosage form includes another substance carrying another medicament in another first medicament-release state having another first bioavailability. The another substance is modifiable ex vivo by an exposure to another first stimulus to carry the another medicament in another second medicament-release state having another second bioavailability. The another substance is modifiable ex vivo by an exposure to another second stimulus to carry the another medicament in another third medicament-release state having another third bioavailability.03-18-2010
20100068266Ex vivo-modifiable multiple-release state final dosage form - Described embodiments include a final dosage form for administering a medicament to an animal, an article of manufacture, and method. A described final dosage form includes a medicament. The final dosage form also includes a release-control substance carrying the medicament in a first medicament-release state wherein the medicament has a first bioavailability to the animal if the final dosage form is administered to the animal. The release-control substance is modifiable ex vivo by an exposure to a first stimulus to carry the medicament in a second medicament-release state wherein the medicament has a second bioavailability to the animal if the final dosage form is administered to the animal. The release-control substance is modifiable ex vivo by an exposure to second stimulus to carry the medicament in a third medicament-release state wherein the medicament has a third bioavailability to the animal if the final dosage form is administered to the animal.03-18-2010
20100068275Personalizable dosage form - Provided embodiments include a final dosage form, an article of manufacture, and a method. A method of fulfilling a request specifying a dose of a medicament for an individual animal includes choosing pursuant to the request an instance of a final dosage form that includes the medicament. The method also includes selecting a stimulus effective to change a medicament-release state of a release element of the final dosage form. The method further includes initiating an ex vivo exposure of the release element of the chosen instance of the final dosage form to the selected stimulus. The method further includes the release element configured in a first medicament-release state and changeable to a second medicament-release state upon an ex vivo exposure to a stimulus.03-18-2010
20100068277Ex vivo modifiable multiple medicament final dosage form - Described embodiments include a final dosage form for administering a medicament to an animal, an article of manufacture, and method. A described final dosage form includes a dosage portion having a medicament and a release element in a first medicament-release state. The medicament has a first bioavailability to the animal. The release element is modifiable ex vivo to a second medicament-release state by an exposure to a stimulus, wherein the medicament has a second bioavailability to the animal. The final dosage form includes another dosage portion having another medicament and another release element in another first medicament-release state. In the another first medicament-release state, the another medicament has another first bioavailability to the animal. The another release element is modifiable ex vivo to another second medicament-release state by an exposure to another stimulus, wherein the another medicament has another second bioavailability to the animal.03-18-2010
20100068278Ex vivo modifiable medicament release-associations - Described embodiments include a final dosage form, an article of manufacture, and method. A described final dosage form includes a medicament, and a substance associated with the medicament in a first release-control state. In the first release-control state, the medicament has a first bioavailability to the animal. The substance is modifiable ex vivo by an exposure to a stimulus to associate with the medicament in a second release-control state, wherein the medicament has a second bioavailability to the animal. The final dosage form also includes another medicament, and another substance associated with the another medicament in another first release-control state. In the another first release-control state, the another medicament has another first bioavailability to the animal. The another substance is modifiable ex vivo by an exposure to another stimulus to associate with the another medicament in another second release-control state, wherein the another medicament has another second bioavailability.03-18-2010
20100068283Ex VIVO modifiable particle or polymeric material medicament carrier - Described embodiments include a final dosage form, an article of manufacture, and method. A final dosage form for administering a medicament to an animal is described. The final dosage form includes the medicament. The final dosage form also includes a particle or polymeric material carrying the medicament in a first medicament-release state wherein the medicament is available to the animal in a first bioavailability if the final dosage form is administered to the animal. The particle or polymeric material is modifiable ex vivo by an exposure to a stimulus to carry the medicament in a second medicament-release state wherein the medicament is available to the animal in a second bioavailability if the final dosage form is administered to the animal. In an embodiment, the final dosage form further includes a transport medium suitable for delivering the particle or polymeric material binding the medicament to the animal.03-18-2010
20100069821Ex vivo modifiable medicament release-sites final dosage form - Described embodiments include a final dosage form, an article of manufacture, and method. A described final dosage form includes a dosage portion having a medicament, and a site and the medicament in a first association. In the first association, the medicament has a first bioavailability. The first association of the site and the medicament is modifiable ex vivo to a second association an exposure to a stimulus, wherein the medicament has a second bioavailability. The final dosage form includes another dosage portion having another medicament, and another site and the another medicament in another first association. In the another first association, the another medicament has another first bioavailability. The another first association is modifiable ex vivo to another second association of the another site and the another medicament by an exposure to another stimulus, wherein the another medicament has another second bioavailability.03-18-2010
20100069822System for ex vivo modification of medicament release state - Described embodiments include a system. A described system includes a computer-readable storage medium configured to indicate a stimulus to modify ex vivo a bioavailability of a medicament carried by a final dosage form based upon a selected medicament bioavailability of the final dosage form. The system also includes a holder configured to establish ex vivo of the animal a location of the final dosage form to receive the indicated stimulus from a stimulus source. The system further includes the stimulus source operable to provide the indicated stimulus. The system also includes a stimulation controller operable to regulate an ex vivo exposure of the final dosage form to the indicated stimulus.03-18-2010
20100069887Multiple chamber ex vivo adjustable-release final dosage form - Described embodiments include a final dosage form, an article of manufacture, and method. A described final dosage form includes a dosage portion having a chamber carrying a medicament. The dosage portion also has a release element in a first medicament-release state wherein the medicament has a first bioavailability to the animal. The release element is modifiable ex vivo to a second medicament-release state by an exposure to a stimulus, wherein the medicament has a second bioavailability to the animal. The final dosage form includes another dosage portion having another chamber carrying another medicament. The another dosage portion also has another release element in another first medicament-release state wherein the another medicament has another first bioavailability to the animal. The another release element is modifiable ex vivo to another second medicament-release state by an exposure to another stimulus, wherein the another medicament has another second bioavailability to the animal.03-18-2010
20100111830Compositions and methods for surface abrasion with frozen particles - Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.05-06-2010
20100111831Compositions and methods for surface abrasion with frozen particles - Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.05-06-2010
20100111832Compositions and methods for surface abrasion with frozen particles - Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.05-06-2010
20100111833Compositions and methods for surface abrasion with frozen particles - Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.05-06-2010
20100111834Compositions and methods for therapeutic delivery with frozen particles - Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.05-06-2010
20100111835Compositions and methods for therapeutic delivery with frozen particles - Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.05-06-2010
20100111836Compositions and methods for therapeutic delivery with frozen particles - Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.05-06-2010
20100111837Compositions and methods for biological remodeling with frozen particle compositions - Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.05-06-2010
20100111841Compositions and methods for surface abrasion with frozen particles - Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.05-06-2010
20100111842Compositions and methods for therapeutic delivery with frozen particles - Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.05-06-2010
20100111843Compositions and methods for therapeutic delivery with frozen particles - Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.05-06-2010
20100111844Compositions and methods for therapeutic delivery with frozen particles - Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.05-06-2010
20100111845Compositions and methods for therapeutic delivery with frozen particles - Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.05-06-2010
20100111846Compositions and methods for delivery of frozen particle adhesives - Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.05-06-2010
20100111847Compositions and methods for administering compartmentalized frozen particles - Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.05-06-2010
20100111848Compositions and methods for administering compartmentalized frozen particles - Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.05-06-2010
20100111849Compositions and methods for administering compartmentalized frozen particles - Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.05-06-2010
20100111850Compositions and methods for administering compartmentalized frozen particles - Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.05-06-2010
20100111854Frozen compositions and methods for piercing a substrate - Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.05-06-2010
20100111855Frozen compositions and methods for piercing a substrate - Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.05-06-2010
20100111857Compositions and methods for surface abrasion with frozen particles - Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.05-06-2010
20100111938Compositions and methods for biological remodeling with frozen particle compositions - Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.05-06-2010
20100112067Compositions and methods for biological remodeling with frozen particle compositions - Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.05-06-2010
20100112068Compositions and methods for biological remodeling with frozen particle compositions - Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.05-06-2010
20100112093Compositions and methods for therapeutic delivery with frozen particles - Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.05-06-2010
20100113614Compositions and Methods for delivery of frozen particle adhesives - Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.05-06-2010
20100113615Compositions and methods for delivery of frozen particle adhesives - Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.05-06-2010
20100114013Compositions and methods for surface abrasion with frozen particles - Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.05-06-2010
20100114267Compositions and methods for surface abrasion with frozen particles - Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.05-06-2010
20100114268Compositions and methods for surface abrasion with frozen particles - Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.05-06-2010
20100114348Frozen compositions and methods for piercing a substrate - Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.05-06-2010
20100114496Compositions and methods for surface abrasion with frozen particles - Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.05-06-2010
20100114497Compositions and methods for therapeutic delivery with frozen particles - Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.05-06-2010
20100114545Compositions and methods for surface abrasion with frozen particles - Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.05-06-2010
20100114546Compositions and methods for therapeutic delivery with frozen particles - Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.05-06-2010
20100114547Compositions and methods for biological remodeling wih frozen particle compositions - Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.05-06-2010
20100114592Compositions and methods for therapeutic delivery with frozen particles - Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.05-06-2010
20100119557Frozen compositions and methods for piercing a substrate - Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.05-13-2010
20100121466Frozen compositions and methods for piercing a substrate - Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.05-13-2010
20100143243Frozen compositions and methods for piercing a substrate - Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.06-10-2010
20100145412System, devices, and methods including actively-controllable sterilizing excitation delivery implants - Systems, devices, methods, and compositions are described for providing an actively-controllable disinfecting implantable device configured to, for example, treat or prevent an infection in a biological subject.06-10-2010
20100152651Frozen compositions and methods for piercing a substrate - Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.06-17-2010
20100262160Adjustable orthopedic implant and method for treating an orthopedic condition in a subject - An orthopedic implant is described including at least one adjustment mechanism configured for securing to at least one orthopedic structure of a subject, and at least one motor operatively connected to the at least one adjustment mechanism, wherein the at least one motor is configured to move the at least one adjustment mechanism in at least three degrees of freedom.10-14-2010
20100262239Adjustable orthopedic implant and method for treating an orthopedic condition in a subject - An orthopedic implant is described including at least one adjustment mechanism configured for securing to at least one orthopedic structure of a subject, and at least one motor operatively connected to the at least one adjustment mechanism, wherein the at least one motor is configured to move the at least one adjustment mechanism in at least three degrees of freedom.10-14-2010
20100294825Steerable surgical stapler - Embodiments include a surgical device and a method. An embodiment of the surgical instrument includes at least one grasping jaw, the at least one grasping jaw being adapted to deliver surgical staples by a force generated from a force generator mechanism that is contained within the at least one grasping jaw or is in a proximity to the at least one grasping jaw. Another embodiment includes at least one grasping jaw, at least one delivery mechanism adapted to deliver surgical fasteners, the delivery mechanism being located in a proximity to or contained within the at least one grasping jaw, the surgical fasteners containing at least one shape-transforming material, at least one sensor, at least one chemical tissue sealant and at least one cutter. A method includes: grasping a body organ/tissue with at least one grasping jaw, adjusting a configuration of the grasping in response to a signal or a datum or an image, and releasing a surgical staple/fastener in response to the signal, datum or image.11-25-2010
20100294826Gentle touch surgical stapler - Embodiments include a surgical device and a method. An embodiment of the surgical instrument includes at least one grasping jaw, the at least one grasping jaw being adapted to deliver surgical staples by a force generated from a force generator mechanism that is contained within the at least one grasping jaw or is in a proximity to the at least one grasping jaw. Another embodiment includes at least one grasping jaw, at least one actuation mechanism adapted to deliver surgical fasteners, the actuation mechanism being located in a proximity to or contained within the at least one grasping jaw, the surgical fasteners containing at least one shape-transforming material, at least one sensor, at least one chemical tissue sealant and at least one cutter. A method includes: grasping a body organ/tissue with at least one grasping jaw, adjusting a configuration of the grasping in response to a signal or a datum or an image, and releasing a surgical staple/fastener in response to the signal, datum or image.11-25-2010
20100294827Maneuverable surgical stapler - Embodiments include a surgical device and a method. An embodiment of the surgical instrument includes at least one grasping jaw, the at least one grasping jaw being adapted to deliver surgical staples by a force generated from a force generator mechanism that is contained within the at least one grasping jaw or is in a proximity to the at least one grasping jaw. Another embodiment includes at least one grasping jaw, at least one delivery mechanism adapted to deliver surgical fasteners, the delivery mechanism being located in a proximity to or contained within the at least one grasping jaw, the surgical fasteners containing at least one shape-transforming material, at least one sensor, at least one chemical tissue sealant and at least one cutter. A method includes: grasping a body tissue with at least one grasping jaw, adjusting a configuration of the grasping in response to a signal or a datum or an image, and releasing a surgical staple/fastener in response to the signal, datum or image.11-25-2010
20100301094Surgical stapling instrument with chemical sealant - Embodiments include a surgical device and a method. An embodiment of the surgical instrument includes at least one grasping jaw, the at least one grasping jaw being adapted to deliver surgical staples by a force generated from a force generator mechanism that is contained within the at least one grasping jaw or is in a proximity to the at least one grasping jaw. Another embodiment includes at least one grasping jaw, at least one actuation mechanism adapted to deliver surgical staples, the actuation mechanism being located in a proximity to or contained within the at least one grasping jaw, the surgical staples containing at least one shape-transforming material, at least one sensor, at least one chemical tissue sealant and at least one cutter. A method includes: grasping a body tissue with at least one grasping jaw, adjusting a configuration of the grasping in response to a signal or a datum or an image, and releasing a surgical staple/fastener in response to the signal, datum or image.12-02-2010
20100331641Devices for continual monitoring and introduction of gastrointestinal microbes - Systems and methods described herein include those for the continual modification of intestinal microbes. Described herein are systems including sampling devices, analysis devices, computational devices and user interface devices as well as methods for the use of such devices in combination.12-30-2010
20110150765Frozen compositions and methods for piercing a substrate - Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.06-23-2011

Patent applications by Edward S. Boyden, Cambridge, MA US