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Edward Mcdonald
Edward Mcdonald, Surrey GB
| Patent application number | Description | Published |
|---|---|---|
| 20090042884 | Pharmaceutical Compounds - Pyrimidines of formula (I): | 02-12-2009 |
| 20090054421 | Pyrimidothiophene Compounds Having HSP90 Inhibitory Activity - Compounds of formula (I) are HSP90 inhibitors, of utility in the treatment of, for example, cancers: wherein R | 02-26-2009 |
| 20090247507 | Enzyme Inhibitors - Compounds of formula (I), are aurora kinase inhibitors: wherein X is —N—, —CH2—N—, —CH2—CH—, or —CH—; R1 is a radical of formula (IA) wherein Z is —CH2—, —NH—, -0-, —S(O)— —S—, —S(O)2 or a divalent monocyclic carbocyclic or heterocyclic radical having 3-7 ring atoms; Alk is an optionally substituted divalent C1-C6 alkylene radical; A is hydrogen or an optionally substituted monocyclic carbocyclic or heterocyclic ring having 5-7 ring atoms; r, s and t are independently 0 or 1, provided that when A is hydrogen then at least one of r and s is 1; R2 is halogen, —CN, —CF3, —OCH3, or cyclopropyl; and R3 is a radical of formula (IB) wherein Q is hydrogen or an optionally substituted phenyl or monocyclic heterocyclic ring with 5 or 6 ring atoms; Z&It;1> is —S—, —S(O)—, —S(O)2—, —O—, —SO2NH—, —NHSO2—, NHC(═O)NH, —NH(C═S)NH—, Or —N(R4)—wherein R4 is hydrogen, C1-C3 alkyl, cycloalkyl, or benzyl; and Alk&It;1> and Alk&It;2> are, independently, optionally substituted divalent C1-C3 alkylene radicals; and m, n and p are independently 0 or 1. Data supplied from the esp@cenet datatbase—Worldwide d77 | 10-01-2009 |
| 20090247579 | 2-[3H-THIAZOL-2-YLIDINEMETHYL]PYRIDINES AND RELATED COMPOUNDS AND THEIR USE - The present invention pertains to certain 2-[3H-thiazol-2-ylidinemethyl]pyridine compounds and analogs thereof, which, inter alia, inhibit cell proliferation, treat cancer, etc., and more specifically to compounds of the following formula, wherein R | 10-01-2009 |
| 20100130496 | PYRIMIDINE DERIVATIVES AS INHIBITORS OF PHOSPHATIDYLINOSITOL-3-KINASE - The invention provides a pyrimidine compound of formula (I): | 05-27-2010 |
| 20100210646 | 2-MORPHOLIN-4-YL-PYRIMIDINES AS PI3K INHIBITORS - The invention provides a pyrimidine compound of formula (I): | 08-19-2010 |
Edward Mcdonald, London GB
| Patent application number | Description | Published |
|---|---|---|
| 20100179138 | Isozazole Compounds As Inhibitors Of Heat Shock Proteins - Isoxazoles of formula (A) or (B) are inhibitors of HSP90 activity, and useful for treatment of, for example cancers: | 07-15-2010 |
Edward Mcdonald, Reigate Surrey GB
| Patent application number | Description | Published |
|---|---|---|
| 20100093769 | COMPOUNDS - The present invention relates to compounds of formula (I) | 04-15-2010 |
Edward Mcdonald, Reigate GB
| Patent application number | Description | Published |
|---|---|---|
| 20090270427 | PURINE DERIVATIVES - The present invention relates to compounds of formula 1 | 10-29-2009 |
| 20090325983 | NEW PURINE DERIVATIVES - The present invention relates to compounds of formula 1 | 12-31-2009 |
Edward Mcdonald, Belmont GB
| Patent application number | Description | Published |
|---|---|---|
| 20090156601 | PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF CANCER - The invention provides compounds which are pyrimidines of formula (I): wherein —XR | 06-18-2009 |
Edward Mcdonald, Sutton GB
| Patent application number | Description | Published |
|---|---|---|
| 20110190297 | PYRIDINE AND PYRIMIDINE BASED COMPOUNDS AS WNT SIGNALING PATHWAY INHIBITORS FOR THE TREATMENT OF CANCER - The present invention relates to pyridine and pyrimidine based compounds, pharmaceutical compositions comprising these compounds and their potential use as therapeutic agents for the treatment and/or prevention of cancer. | 08-04-2011 |