Patent application number | Description | Published |
20130244332 | TAREGTED INTEGRATION AND EXPRESSION OF EXOGENOUS NUCLEIC ACID SEQUENCES - Disclosed herein are methods and compositions for targeted integration of a exogenous sequence into a predetermined target site in a genome for use, for example, in protein expression and gene inactivation. | 09-19-2013 |
20130253040 | METHODS AND COMPOSITIONS FOR TREATING HUNTINGTON'S DISEASE - Disclosed herein are methods and compositions for treating or preventing Huntington's Disease. | 09-26-2013 |
20140017212 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF LYSOSOMAL STORAGE DISEASES - Nucleases and methods of using these nucleases for inserting a sequence encoding a therapeutic protein such as an enzyme into a cell, thereby providing proteins or cell therapeutics for treatment and/or prevention of a lysosomal storage disease. | 01-16-2014 |
20140080216 | METHODS AND COMPOSITIONS FOR TREATMENT OF A GENETIC CONDITION - Methods and compositions for a genetic disease are provided. | 03-20-2014 |
20140093913 | METHODS AND COMPOSITIONS FOR TREATMENT OF A GENETIC CONDITION - Methods and compositions for a genetic disease are provided. | 04-03-2014 |
20140112896 | METHODS AND COMPOSITIONS FOR THE PROVISION OF PROTEINS DEFICIENT IN LYSOSOMAL STORAGE DISEASES - Nucleases and methods of using these nucleases for inserting a sequence encoding a therapeutic protein such as an enzyme into a cell, thereby providing proteins or cell therapeutics for the provision of proteins lacking or deficient in subjects with a lysosomal storage disease and treatment and/or prevention of lysosomal storage diseases. | 04-24-2014 |
20140134723 | NOVEL DNA-BINDING PROTEINS AND USES THEREOF - Disclosed herein are polypeptides, polynucleotides encoding, cells and organisms comprising novel DNA-binding domains, including TALE DNA-binding domains. Also disclosed are methods of using these novel DNA-binding domains for modulation of gene expression and/or genomic editing of endogenous cellular sequences. | 05-15-2014 |
20140134740 | NOVEL DNA-BINDING PROTEINS AND USES THEREOF - Disclosed herein are polypeptides, polynucleotides encoding, cells and organisms comprising novel DNA-binding domains, including TALE DNA-binding domains. Also disclosed are methods of using these novel DNA-binding domains for modulation of gene expression and/or genomic editing of endogenous cellular sequences. | 05-15-2014 |
20140134741 | NOVEL DNA-BINDING PROTEINS AND USES THEREOF - Disclosed herein are polypeptides, polynucleotides encoding, cells and organisms comprising novel DNA-binding domains, including TALE DNA-binding domains. Also disclosed are methods of using these novel DNA-binding domains for modulation of gene expression and/or genomic editing of endogenous cellular sequences. | 05-15-2014 |
20140287500 | COMPOSITIONS FOR LINKING ZINC FINGER MODULES - Disclosed herein are compositions for linking DNA binding modules to allow for specific and selective binding to module subsites separated by 1 or more base pairs. Also described are methods of making and using compositions comprising these linkers. | 09-25-2014 |
20140336133 | METHODS AND COMPOSITIONS FOR TREATING HUNTINGTON'S DISEASE - Disclosed herein are methods and compositions for treating or preventing Huntington's Disease. | 11-13-2014 |
20150056705 | METHODS AND COMPOSITIONS FOR TREATMENT OF A GENETIC CONDITION - Methods and compositions for genetic alteration of cells are provided. | 02-26-2015 |