| Patent application number | Description | Published |
| 20080228208 | INTRALUMENAL MATERIAL REMOVAL USING A CUTTING DEVICE FOR DIFFERENTIAL CUTTING - Intralumenal material removal systems are provided using an advanceable and rotatable cutter assembly designed for differential cutting. The intralumenal material removal system includes a cutter assembly positionable in the body cavity of a mammalian subject. One embodiment of the cutter assembly comprises a cutter with blades that are designed and arranged to form an acute blade angle of attack with the matter-to-be-removed. The cutter assembly is axially advanceable by translating the drive shaft and rotatable by rotating the drive shaft. The occlusive material is scraped by the cutter assembly and may be aspirated to remove the material from the body cavity. The cutter assembly may provide aspiration ports positioned between facing surfaces of the blades. | 09-18-2008 |
| 20100324472 | DELIVERY AND ADMINISTRATION OF COMPOSITIONS USING INTERVENTIONAL CATHETERS - Systems and methods for delivery of therapeutic and/or diagnostic compositions to an interventional site having diseased or newly treated tissue are provided. Integrated interventional catheter systems incorporating surfaces coated with a therapeutic composition, or tissue penetration members for scoring or disrupting tissue prior to or during administration of a therapeutic composition are provided. Infusion of therapeutic composition(s) may also be provided. | 12-23-2010 |
| 20110040238 | INTERVENTIONAL CATHETER ASSEMBLIES INCORPORATING GUIDE WIRE BRAKE AND MANAGEMENT SYSTEMS - Interventional catheter assemblies that operate over a guide wire and incorporate guide wire management systems are disclosed. Specifically, a guide wire buffer zone is provided between a proximal end of the interventional catheter and the guide wire clamp that accommodates variable lengths of exposed guide wire in an unrestrained condition when the guide wire is clamped, allowing the distal end of the operating catheter to be advanced and retracted over the distal end of the guide wire without repositioning and reclamping the proximal end of the guide wire. The configuration of the guide wire buffer zone may be adjusted prior to or during an intervention based on the anticipated range of axial motion of the catheter and operating head relative to the guide wire. | 02-17-2011 |
| 20110071440 | INTERVENTIONAL CATHETERS INCORPORATING ASPIRATION AND/OR INFUSION SYSTEMS - An interventional catheter assembly comprising a catheter for insertion and guidance to a target site in a body lumen or a cavity and an operating head mounted in proximity to a distal end of the catheter and comprising a system for removing obstructive material from the target site is provided. In certain embodiments, the catheter assembly includes at least one aspiration port located proximal to the operating head that communicates with a first sealed lumen for withdrawing fluids and obstructive material from the target site, together with at least one liquid infusion port penetrating the catheter and located proximal to the at least one aspiration port that communicates with a second sealed lumen for supplying fluid to a location in proximity to the target site. | 03-24-2011 |
| 20110151463 | METHODS AND SYSTEMS FOR BIOLOGICAL SAMPLE COLLECTION AND ANALYSIS - Filtration devices for collection and filtration of biological samples are disclosed. Devices having a filtration element oriented in a generally vertical orientation are provided, as well as filtration devices that incorporate a cooling mechanism to reduce the temperature of collected solids. Tissue collection devices, such as aspiration assemblies, tissue sampling devices, and the like incorporating filtration devices are disclosed. Methods of collecting biological samples and separating biological solids from a liquid/solids mixture are also disclosed, together with analytical techniques and protocols for analyzing biological samples. | 06-23-2011 |