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Edward I.

Edward I. Ginns, Shrewsbury, MA US

Patent application numberDescriptionPublished
20090209624COMPOSITIONS AND THEIR USES FOR GENE THERAPY OF BONE CONDITIONS - In certain preferred embodiments, the present invention provides compositions and methods for the treatment of bone conditions associated with low bone density. In preferred embodiments, the present invention provides compositions and methods for the treatment of osteoprotegerin-responsive conditions.08-20-2009
20120039929NOVEL THERAPY FOR LYSOSOMAL ENZYME DEFICIENCIES - The present invention provides a therapeutic delivery system comprising an extracted yeast cell wall comprising beta-glucan, a payload trapping molecule and a payload molecule, wherein the payload molecule and the payload trapping molecule are soluble in the same solvent system wherein the payload molecule supplements the function of the deficient lysosomal enzyme. The invention further provides methods of making and methods of using the therapeutic delivery system.02-16-2012

Patent applications by Edward I. Ginns, Shrewsbury, MA US

Edward I. Mishan, New York, NY US

Patent application numberDescriptionPublished
20120058867ABDOMINAL EXERCISER WITH ROTATABLE SEAT AND TANDEM PULLEY FEATURES - An abdominal exerciser has base and back frames pivotally mounted for movement between upright and recumbent positions, and a seat frame with cushion rotatable on the base frame. A low friction journal between the base and seat frames supports a user's weight. The journal is about 30 to 42% the distance from a rear end of the cushion to its front end so the user's coccyx is vertically aligned with the journal. Arms at each side of the base frame have a pair of extensions connected to either the base or seat frame, each with a U-shaped handhold lying in a plane at an acute angle of about 30 to 80 degrees to the horizontal. A pair of single pulleys or a pair of tandem pulleys are mounted near the rear of the base frame and are engaged by sleeve-covered springs for biasing the back frame toward the upright position.03-08-2012

Edward I. Shie, Foster City, CA US

Patent application numberDescriptionPublished
20100138344MOBILE BARCODE GENERATION AND PAYMENT - An application on user's mobile device (having a display screen) generates a one-time use and time-limited barcode on the display when the user enters a PIN. The barcode can be scanned to make purchases at a point of sale (POS).06-03-2010

Edward I. Wulfman, Woodinville, WA US

Patent application numberDescriptionPublished
20080228208INTRALUMENAL MATERIAL REMOVAL USING A CUTTING DEVICE FOR DIFFERENTIAL CUTTING - Intralumenal material removal systems are provided using an advanceable and rotatable cutter assembly designed for differential cutting. The intralumenal material removal system includes a cutter assembly positionable in the body cavity of a mammalian subject. One embodiment of the cutter assembly comprises a cutter with blades that are designed and arranged to form an acute blade angle of attack with the matter-to-be-removed. The cutter assembly is axially advanceable by translating the drive shaft and rotatable by rotating the drive shaft. The occlusive material is scraped by the cutter assembly and may be aspirated to remove the material from the body cavity. The cutter assembly may provide aspiration ports positioned between facing surfaces of the blades.09-18-2008
20100324472DELIVERY AND ADMINISTRATION OF COMPOSITIONS USING INTERVENTIONAL CATHETERS - Systems and methods for delivery of therapeutic and/or diagnostic compositions to an interventional site having diseased or newly treated tissue are provided. Integrated interventional catheter systems incorporating surfaces coated with a therapeutic composition, or tissue penetration members for scoring or disrupting tissue prior to or during administration of a therapeutic composition are provided. Infusion of therapeutic composition(s) may also be provided.12-23-2010
20110040238INTERVENTIONAL CATHETER ASSEMBLIES INCORPORATING GUIDE WIRE BRAKE AND MANAGEMENT SYSTEMS - Interventional catheter assemblies that operate over a guide wire and incorporate guide wire management systems are disclosed. Specifically, a guide wire buffer zone is provided between a proximal end of the interventional catheter and the guide wire clamp that accommodates variable lengths of exposed guide wire in an unrestrained condition when the guide wire is clamped, allowing the distal end of the operating catheter to be advanced and retracted over the distal end of the guide wire without repositioning and reclamping the proximal end of the guide wire. The configuration of the guide wire buffer zone may be adjusted prior to or during an intervention based on the anticipated range of axial motion of the catheter and operating head relative to the guide wire.02-17-2011
20110071440INTERVENTIONAL CATHETERS INCORPORATING ASPIRATION AND/OR INFUSION SYSTEMS - An interventional catheter assembly comprising a catheter for insertion and guidance to a target site in a body lumen or a cavity and an operating head mounted in proximity to a distal end of the catheter and comprising a system for removing obstructive material from the target site is provided. In certain embodiments, the catheter assembly includes at least one aspiration port located proximal to the operating head that communicates with a first sealed lumen for withdrawing fluids and obstructive material from the target site, together with at least one liquid infusion port penetrating the catheter and located proximal to the at least one aspiration port that communicates with a second sealed lumen for supplying fluid to a location in proximity to the target site.03-24-2011
20110151463METHODS AND SYSTEMS FOR BIOLOGICAL SAMPLE COLLECTION AND ANALYSIS - Filtration devices for collection and filtration of biological samples are disclosed. Devices having a filtration element oriented in a generally vertical orientation are provided, as well as filtration devices that incorporate a cooling mechanism to reduce the temperature of collected solids. Tissue collection devices, such as aspiration assemblies, tissue sampling devices, and the like incorporating filtration devices are disclosed. Methods of collecting biological samples and separating biological solids from a liquid/solids mixture are also disclosed, together with analytical techniques and protocols for analyzing biological samples.06-23-2011

Patent applications by Edward I. Wulfman, Woodinville, WA US