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Edward D. Daugs, Midland US

Edward D. Daugs, Midland, MI US

Patent application numberDescriptionPublished
20080221018Crystalline solid and amorphous forms of (-)- halofenate and methods related thereto - The present invention provides crystalline solid and amorphous forms of (−)-halofenate. The crystalline solid forms may be used in various pharmaceutical compositions, and are particularly effective for the prevention and/or treatment of conditions associated with blood lipid deposition in a mammal, particularly those diseases related to Type 2 diabetes and hyperlipidemia. The invention also relates to a method for preventing or treating Type 2 diabetes and hyperlipidemia in a mammal comprising the step of administering a therapeutically effective amount of crystalline solid and amorphous forms of (−)-halofenate.09-11-2008
20090247744HYDROFORMYLATION PROCESS FOR PHARMACEUTICAL INTERMEDIATE - The invention relates to an improved process for the preparation of an advanced synthetic intermediate of ACE inhibitors. In one aspect, the present invention is based on a novel process for the preparation of an aldehyde of formula (I), wherein (N)10-01-2009
20090281359PROCESS FOR OLEFIN ETHERIFICATION - The invention relates to processes for the etherification of olefins with alcohols. According to one aspect, a heterogeneous etherification catalyst is used under conditions that permit limiting the contact time between the desired product and the catalyst, thereby mitigation reverse reactions. According to a second aspect, a recycling process is used that significantly increases the yield of desired product.11-12-2009
20100041160ANALYSIS OF HIGH MOLECULAR WEIGHT MPEG ALCOHOL COMPOSITIONS - The invention is directed toward novel high molecular weight and high purity mPEG alcohol compositions as well as a process for obtaining said compositions by removing PEG diols from the mPEG alcohol after polymerization is complete.02-18-2010
20110009675Process for the Continuous Production of High Purity Phenolic Glycol Ether - Phenolic glycol ethers, e.g., ethylene glycol phenyl ether, are prepared by a continuous, nonaqueous process comprising the steps of (A) contacting under isothermal reactive conditions in a first reactor or reaction zone an alkylene oxide, e.g., ethylene oxide, with (i) a stoichiometric molar excess of a phenolic compound, e.g., phenol, and (ii) a catalytic amount of a base, e.g., sodium hydroxide, homogeneously dispersed throughout the phenolic compound, to form a first intermediate phenolic glycol ether product, (Bj transferring the first intermediate phenolic glycol ether product to a second reactor or reaction zone, and (C) subjecting the first intermediate phenolic glycol ether product to adiabatic reactive conditions in the second reactor or reaction zone to form a second intermediate phenolic glycol ether product comprising phenolic glycol ether, unreacted phenolic compound, catalyst, water and byproduct glycols. In addition, the mono-/di-product weight ratio can be adjusted by increasing or decreasing the amount of base catalyst employed.01-13-2011
20110015111SULFONATE SURFACTANTS AND METHODS OF PREPARATION AND USE - Provided are new anionic surfactants and methods of their preparation and use. The surfactants are compounds of the formula I:01-20-2011
20110105507VINYL ETHER COMPOUNDS AND METHODS OF THEIR PREPARATION AND USE - Provided are new functionalized surfactants and methods of their preparation and use. The surfactants are compounds of formula I:05-05-2011
20110112328Difunctional, Amine-Based Surfactants, and Their Precursors, Preparation, Compositions and Use - Cationic surfactants of formula I05-12-2011

Patent applications by Edward D. Daugs, Midland, MI US