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| 20080219879 | THIN CAST STRIP PRODUCT WITH MICROALLOY ADDITIONS, AND METHOD FOR MAKING THE SAME - A steel product or thin steel cast strip comprised of, by weight, less than 0.25% carbon, between 0.20 and 2.0% manganese, between 0.05 and 0.50% silicon, less than 0.01% aluminum, and at least one of niobium between 0.01% and 0.20% and vanadium between 0.01% and 0.20%, and having a microstructure of a majority bainite and acicular ferrite, and more than 70% niobium and/or vanadium in solid solution. The steel product may have an increase in elongation and an increase in yield strength after age hardening. The age hardened steel product may have niobium carbonitride particles with an average particle size of 10 nanometers and less, and may have substantially no niobium carbonitride particles greater than 50 nanometers. The steel product may have a yield strength of at least 380 MPa or a tensile strength of at least 410 MPa, or both. The steel product or thin cast steel strip may have a total elongation of at least 6% or 10%. | 09-11-2008 |
| 20100186856 | HIGH STRENGTH THIN CAST STRIP PRODUCT AND METHOD FOR MAKING THE SAME - A steel product or thin steel cast strip including, by weight, less than 0.25% carbon, between 0.20 and 2.0% manganese, between 0.05 and 0.50% silicon, less than 0.01% aluminum, and at least one of niobium between 0.01% and 0.20% and vanadium between 0.01% and 0.20%, and a microstructure of a majority bainite and acicular ferrite, and more than 70% niobium and/or vanadium in solid solution. The steel product may have an increase in elongation and an increase in yield strength after age hardening. The age hardened steel product may have niobium carbonitride particles with an average particle size of 10 nanometers and less, and may have substantially no niobium carbonitride particles greater than 50 nanometers. The steel product may have a yield strength of at least 380 MPa, a tensile strength of at least 410 MPa, or both. The product may have a total elongation of at least 6% or 10%. | 07-29-2010 |
| 20100215539 | HOT ROLLED THIN CAST STRIP PRODUCT AND METHOD FOR MAKING THE SAME - A hot rolled steel strip made by the steps including assembling a twin roll caster, forming a casting pool of molten steel of such composition that the cast strip produced comprises by weight, greater than 0.25% and up to 1.1% carbon, between 0.40 and 2.0% manganese, between 0.05 and 0.50% silicon, less than 0.01% aluminum, counter rotating the casting rolls to solidify metal shells and forming a steel strip, hot rolling the steel strip such that mechanical properties at 10% and 35% reduction are within 10% for yield strength, tensile strength and total elongation, and coiling the hot rolled steel strip at a temperature between 550 and 750° C. to provide a majority of the microstructure comprising pearlite, along with bainite and acicular ferrite. The steel may have a free oxygen content between 5 and 50 ppm or between 25 and 45 ppm. | 08-26-2010 |
| 20100215981 | HOT ROLLED THIN CAST STRIP PRODUCT AND METHOD FOR MAKING THE SAME - A hot rolled steel strip made by the steps including assembling a twin roll caster, forming a casting pool of molten steel having a free oxygen content between 20 and 75 ppm and having a composition such that the cast strip comprises by weight, less than 0.25% carbon, between 0.9 and 2.0% manganese, between 0.05 and 0.50% silicon, greater than 0.01% and less than or equal to 0.15% phosphorus, and less than 0.01% aluminum, counter rotating the casting rolls forming the steel strip, hot rolling the strip such that mechanical properties at 10% and 35% reduction are within 10% for yield strength, tensile strength and total elongation, and coiling the strip at a temperature between 300 and 700° C. to provide a majority of the microstructure comprising bainite and acicular ferrite. Alternatively, the steel may have between 0.20 and 0.60% copper and manganese as low as 0.08%. | 08-26-2010 |
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| 20100063452 | Flexible Disposable Surgical Port - A surgical apparatus for introduction of laparoscopic instruments into an anatomical cavity through tissue at an entry site. The apparatus includes a body with a frustoconical-shaped wall. The body defines an interior cavity, an open bottom, and a substantially closed top wall with openings from which a plurality of ports extend upward therefrom. The ports are adapted to receive the laparoscopic instruments for introduction through the interior cavity and open bottom of the body into the anatomical cavity. In the preferred embodiment, the frustoconical-shaped wall of the body is placed through an incision in the umbilicus. In one aspect of the invention, the body is a unitary one-piece molded structure. A reinforcing belt or plate formed from a relatively hard material can be integral to the body. In another aspect, the apparatus is formed from a block copolymer of poly(styrene-block-isobutylene-block-styrene), hereinafter referred to as “SIBS”, which unexpectedly provides the benefit that lubrication of the ports (or of the instruments extending through the ports) is avoided. | 03-11-2010 |
| 20110166425 | Flexible Disposable Surgical Port - A surgical apparatus for introduction of laparoscopic instruments into an anatomical cavity through tissue at an entry site. The apparatus includes a body with a frustoconical-shaped wall. The body defines an interior cavity, an open bottom, and a substantially closed top wall with openings from which a plurality of ports extend upward therefrom. The ports are adapted to receive the laparoscopic instruments for introduction through the interior cavity and open bottom of the body into the anatomical cavity. In the preferred embodiment, the frustoconical-shaped wall of the body is placed through an incision in the umbilicus. In one aspect of the invention, the body is a unitary one-piece molded structure. A reinforcing belt or plate formed from a relatively hard material can be integral to the body, and separately formed port caps each having a septum may be bonded to the ports. | 07-07-2011 |
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| 20080260802 | Biocompatible hydrogels made with small molecule precursors - Biocompatible crosslinked polymers, and methods for their preparation and use, are disclosed in which the biocompatible crosslinked polymers are formed from water soluble precursors having electrophilic and nucleophilic functional groups capable of reacting and crosslinking in situ. Methods for making the resulting biocompatible crosslinked polymers biodegradable, or not, are provided, as are methods for controlling the rate of degradation. The crosslinking reactions may be carried out in situ on organs or tissues or outside the body. Applications for such biocompatible crosslinked polymers and their precursors include controlled delivery of drugs, prevention of post-operative adhesions, coating of medical devices such as vascular grafts, wound dressings and surgical sealants. Visualization agents may be included with the crosslinked polymers. Embodiments that include hydrogels having isolated hydrolytically degradable esters are set forth. Embodiments including the use of low molecular weight amines to make degradable hydrogels are also set forth. | 10-23-2008 |
| 20080286333 | Medical devices having coating with improved adhesion - According to an aspect of the present invention, a medical device is provided which comprises a metallic substrate and polymeric region disposed over and in contact with the metallic substrate. The polymeric region comprises (a) a block copolymer that comprises (i) a hard polymer block that comprises a high Tg monomer and (ii) a soft polymer block that comprises a low Tg monomer, (b) an adhesion promoting copolymer that comprises (i) a first monomer that covalently or non-covalently bonds with the metallic substrate and (ii) a second monomer that is compatible with the low Tg monomer and/or the high Tg monomer and (c) a therapeutic agent. The polymeric region may further comprise an optional polymer that is used to tailor the release rate of the therapeutic agent. | 11-20-2008 |
| 20090076595 | Medical devices having bioerodable layers for the release of therapeutic agents - According to an aspect of the present invention, medical devices are provided which comprise: (a) a substrate and (b) bioerodable polymeric layer over the substrate that contains (i) one or more biodegradable polymers, (ii) one or more therapeutic agents, and (iii) one or more plasticizers. | 03-19-2009 |
| 20100030313 | MEDICAL ARTICLES COMPRISING BIODEGRADABLE BLOCK COPOLYMERS - The present invention is directed to medial articles having bioerodible polymeric regions that contain biodegradable block copolymers. The biodegradable block copolymers include at least one first biodegradable polymer block and least one second biodegradable polymer block that differs from the first biodegradable polymer block. The bioerodible polymeric regions comprise a first phase domain formed from the at least one first biodegradable polymer block and a second phase domain formed from the at least one second biodegradable polymer block. At least one of the first and second phase domains is a discontinuous phase domain in the form of dispersed phase elements, substantially all of which have a longest cross-sectional dimension that is less than 1 micron. | 02-04-2010 |
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| 20080272776 | MAGNETIC RESONANCE IMAGE ACQUISITION WITH SUPPRESSION OF BACKGROUND TISSUES AND RF WATER EXCITATION AT OFFSET FREQUENCY - Background tissue signals such as water and/or fat are suppressed in an MR image by using an imaging agent that chemically shifts the tissue spins of interest. An imaging pulse sequence is used to acquire the image data using an RF excitation pulse that is tuned to the off-resonance tissue spins of interest with the saturation pulse sequences being interleaved with the imaging pulse sequences to selectively suppress signals from on-resonance background tissues such as water and/or fat. | 11-06-2008 |
| 20090143666 | System And Method For Non-Contrast Agent MR Angiography - A system and method for imaging a desired region of the circulatory system uses the subtraction of data from two acquisitions using substantially different RF pulses and/or pulse sequence timing parameters. In one or both data sets, the longitudinal magnetization of spins within a selected imaging volume has been altered by the application of one or more RF preparatory (prep) pulses. The prep is applied in such a way that subtraction eliminates signals from static background spins, such as fat, while maintaining the signal intensity of intravascular spins. | 06-04-2009 |
| 20100134103 | System and Method For Ghost Magnetic Resonance Imaging - A system and method enables the creation of medical images using data related to ghost artifacts. The method thus allows components of an imaged subject to be segmented based on state changes in the components that lead to the controlled production of ghost artifacts. This is achieved in MR by performed a pulse sequence so that multiple sets of MR data are acquired in which the signals from a target tissue vary across the data sets while the signals from a background tissue do not vary across the data sets. A composite data set is generated by populating selected k-space lines of the composite data set with information from a first MR data set and populating the remaining k-space lines of the composite data set with information from a second MR data set. An MR image is then reconstructed from the composite data set. The MR image contains ghost artifacts that faithfully reproduce the 2D or 3D anatomic detail of the target tissues without signal contributions from the background tissues, allowing for background-suppressed or segmented MR images of a target tissue without the need for image subtraction. | 06-03-2010 |
| 20100201361 | SYSTEM AND METHOD FOR PASSIVE CATHETER TRACKING WITH MAGNETIC RESONANCE IMAGING - Background tissue signals such as water and/or fat are suppressed in an MR image by using an imaging agent that chemically shifts the tissue spins of interest. An imaging pulse sequence is used to acquire the image data using an RF excitation pulse that is tuned to the off-resonance tissue spins of interest with the saturation pulse sequences being interleaved with the imaging pulse sequences to selectively suppress signals from on-resonance background tissues such as water and/or fat. | 08-12-2010 |
| 20100268062 | METHOD FOR NON-CONTRAST ENHANCED MAGNETIC RESONANCE ANGIOGRAPHY - A method for non-contrast enhanced magnetic resonance angiography (“MRA”) that has a short scan time and is insensitive to patient motion is provided. More particularly, the method provides significant arterial conspicuity and substantial venous signal suppression. A two-dimensional single shot acquisition is employed and timed to occur a specific time period after the occurrence of an R-wave in a contemporaneously recorded electrocardiogram. In this manner, k-space data is acquired that is substantially insensitive to variations in arterial flow velocity, or heart rate, and that further substantially suppresses unwanted venous signal in a prescribed imaging slice. | 10-21-2010 |
| 20110080166 | Parallel-Accelerated Complex Subtraction MRI - A method for producing background-suppressed MR images with improved resistance to subject motion and noise, particularly that associated with parallel imaging techniques. An MRI system is employed to acquire two sets of undersampled k-space data under different scan conditions. A differential k-space data set is then formed by complex, pairwise subtraction of the two undersampled k-space data sets and a background-suppressed MR is reconstructed from the differential k-space data set using an accelerated reconstruction technique, such as GRAPPA. | 04-07-2011 |
| 20110137146 | Method for Non-Contrast Enhanced Magnetic Resonance Angiography - A method for non-contrast enhanced magnetic resonance angiography (“MRA”) that has a short scan time and is insensitive to patient motion is provided. More particularly, the method provides significant arterial conspicuity and substantial venous signal suppression. A two-dimensional single shot acquisition is employed and timed to occur a specific time period after the occurrence of an R-wave in a contemporaneously recorded electrocardiogram. In this manner, k-space data is acquired that is substantially insensitive to variations in arterial flow velocity, or heart rate, and that further substantially suppresses unwanted venous signal in a prescribed imaging slice. | 06-09-2011 |
| 20110166436 | System and Method For Non-Contrast MR Angiography Using Steady-State Image Acquisition - A system and method is provided to quickly acquire and produce an MR angiogram without the use of a contrast agent. In quick succession, two MR image data sets of the vasculature of interest are acquired using a steady-state free precession (SSFP) pulse sequence. The SSFP pulse sequence gradient pulses differ for each image acquisition in that gradient pulses are balanced, or first moment nulled, for one acquisition, but not the other. Magnitude images are reconstructed from the two acquired image data sets and the magnitude images are subtracted to produce the MR angiogram. Contrast is provided by spin motion without the use of contrast agents and without the time consuming addition of motion encoding gradients or preparatory pulse sequences. | 07-07-2011 |
| 20110260725 | Time Resolved Spin Labeled MRI Cineangiography - A sequence of magnetic resonance images of the beating heart depicts the flow of blood through the heart chambers. Blood appears bright and background tissues are darkened by acquiring MR data following a preparatory pulse sequence in which spin magnetization throughout the field of view is inverted using a non-selective RF inversion pulse and spin magnetization in a selected pool of blood moving into the heart is re-inverted by a selective RF inversion pulse. | 10-27-2011 |
