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Ebinuma, JP
Hiroyasu Ebinuma, Tokyo JP
| Patent application number | Description | Published |
|---|---|---|
| 20080292732 | Plant and Plant Storage Organ Having Glp-1 Derivative Accumulated Therein and Method of Producing the Same - The present invention is to provide a plant and a plant storage organ thereof in which GLP-1 derivatives are accumulated, and a method of producing them in order to develop a method for ingesting orally GLP-1 derivatives at a low cost and to make use of it in diabetic treatment. A transgenic plant or a plant storage organ thereof in which GLP-1 derivatives are accumulated cleavable with a digestive enzyme is produced by a method comprising: integrating into a vector a linked GLP-1s-DNA which comprises tandem repeated “n” DNAs (“n” being an integer of 3 or more) encoding a GLP-1 derivative consisting of GLP-1 (7-36) or of an amino acid sequence of GLP-1 (7-36) in which one or a few amino acids are deleted, substituted and/or added, and C-terminal consists of Arg or Lys, and having GLP-1 activity; introducing the vector into a plant cell; and redifferentiating the obtained transformant. The transgenic plant and the plant storage organ are useful as a pharmaceutical composition or a food or drink for treating or preventing diabetes. | 11-27-2008 |
| 20090320164 | METHOD FOR PRODUCTION OF PLANT CELL HAVING CHROMOSOME LOSS - The present invention provides a simple aneuploid production process, applicable to all species, without producing unexpected damage to chromosomes other than a chromosome which is to be disappeared. A vector comprising two site-specific recognition sequences oriented in the opposite direction, or one site-specific recombinase recognition sequence comprising a point-symmetric nucleotide sequence, and a recombinase gene is introduced into a plant cells or a vector comprising two site-specific recognition sequences oriented in the opposite directions or one site-specific recombinase recognition sequence comprising a point-symmetric nucleotide sequence is introduced into a plant cell; a recombinase is allowed to act transiently in the cell during at least growth of the cell; and the cell is cultured and grown; and a cell in which a predetermined chromosome is disappeared is selected. | 12-24-2009 |
| 20110203016 | PROCESS FOR PRODUCING PLANT STORAGE ORGAN WITH HIGH PRODUCTION OF RECOMBINANT PROTEIN AND NOVEL RECOMBINANT PROTEIN - The present invention provides a method for highly producing a recombinant protein in a plant storage organ and a GLP-1 derivative. The plant storage organ in which the recombinant protein is highly produced is obtained by transformation with the use of a vector which comprises a recombinant protein gene, a cytokinin-related gene, a drug-resistant gene and a removable DNA element, in which the cytokinin-related gene and the drug-resistant gene exist in the positions so that they can behave together with the DNA element, while the recombinant protein to be expressed in the plant storage organ exists in the position so that it would not behave together with the DNA element. The GLP-1 is produced by using the method, and a derivative having been stabilized against enzymatic digestion is further provided. | 08-18-2011 |
Hiroyuki Ebinuma, Ibaraki JP
| Patent application number | Description | Published |
|---|---|---|
| 20080233605 | Method of Assaying Glycated Protein - The present invention provides a convenient, efficient method for assaying glycated protein, fructosyl peptide, or fructosyl amino acid which can be performed with reduced effect of fructosyl lysine compounds. The invention also provides a reagent for the assay. | 09-25-2008 |
| 20100330600 | HIGH-MOLECULAR-WEIGHT ADIPONECTIN MEASUREMENT METHOD - Provided is a method of separating and measuring highly active HMW adiponectin in adiponectin multimers. A method of measuring high-molecular-weight adiponectin in a sample, wherein adiponectin multimers are separated by use of a protease and measured immunologically, the method comprising reacting a sample containing adiponectin multimers with chymotrypsin. | 12-30-2010 |
| 20110091993 | METHOD FOR QUANTIFICATION OF SOLUBLE LR11 - Provided is a method for quantifying soluble LR11 in a biological sample such as serum by an immunological means conveniently and accurately without the need of carrying out any complicated separation manipulation. An immunological quantification method for soluble LR11 in a sample derived from a mammal, including a step of treating the sample with at least one surfactant selected from a group consisting of a polyoxyalkylene alkyl ether, a polyoxyalkylene alkyl phenyl ether, an alkyl glycoside, an alkylthio glycoside, an acyl-N-methylglucamide and a salt of cholic acid. | 04-21-2011 |
| 20110177610 | NOVEL MARKER FOR ARTERIOSCLEROTIC DISEASE - Disclosed is a novel marker for an arteriosclerotic disease. Also disclosed is a method for evaluating the presence or level of an arteriosclerotic disease in a mammal, or a method for evaluating the prophylactic or therapeutic effect on an arteriosclerotic disease in a mammal, which is characterized by detecting a soluble LR11 in a sample collected from the mammal. | 07-21-2011 |
Hiroyuki Ebinuma, Ryugasaki-Shi JP
| Patent application number | Description | Published |
|---|---|---|
| 20090291461 | METHOD OF SELECTIVELY ASSAYING ADIPONECTIN MULTIMERS - Kits and methods for selectively assaying a target adiponectin multimer in a biological sample. Such methods accurately evaluate the relationship between a disease and adiponectin through selective assay of adiponectin multimers and provide information that cannot be obtained through measurement of the total amount of adiponectin alone. A method for selectively assaying a target adiponectin multimer in a biological sample comprising distinguishing target adiponectin multimer from the other adiponectin multimers by using a protease and/or an antibody. | 11-26-2009 |
Hiroyuki Ebinuma, Fukaya-Shi JP
| Patent application number | Description | Published |
|---|---|---|
| 20090096923 | SYNC SEPARATION CIRCUIT - A sync separation circuit separates a synchronizing signal from a video signal containing the synchronizing signal. A minimum level detecting section detects a minimum level of a video signal. A sync tip level detecting section detects a sync tip level in the video signal. A pedestal level detecting section detects a pedestal level in the video signal. Based on both the sync tip level detected by the sync tip level detecting section and the pedestal level control by the pedestal level detecting section, a slice level setting section sets a slice level corresponding to an intermediate value between the sync tip level and the pedestal level. The slice level control section sets the slice level based on the minimum level detected by the minimum level detecting section if the slice level set based on the sync tip level and the pedestal level is inappropriate. | 04-16-2009 |
| 20090096926 | AUTOMATIC GAIN CONTROL CIRCUIT IN VIDEO SIGNAL PROCESSING DEVICE - In an automatic gain control circuit comprising a black level detecting unit which detects a black level from a video signal, a white level detecting unit which detects a white level from the video signal, and an analog-to-digital converter which adjusts a dynamic range of the video signal based on a difference value between the black level and the white level, a video signal for adjustment including a black level which indicates a minimum brightness of a video image and a white level which indicates a maximum brightness of the video image is input and the dynamic range is adjusted. | 04-16-2009 |
| 20090096928 | COLOR KILLER CIRCUIT - There is provided a color killer circuit comprising a burst amplitude detection unit that detects an amplitude of a color burst; a delay unit that stores, delays, by a predetermined period of time, and outputs the detected amplitude; a subtractor that calculates a difference between an output from the burst amplitude detection unit and an output from the delay unit; a first comparator that compares the output from the burst amplitude detection unit with a first threshold value to determine whether or not the output from the burst amplitude detection unit is less than the first threshold value; and a second comparator that compares an output from the subtractor with a second threshold value to determine whether or not the output from the subtractor is greater than the second threshold value, wherein the color killer circuit masks the color component of the composite video signal when the first comparator determines that the output from the burst amplitude detection unit is less than the first threshold value, or when the second comparator determines that the output from the subtractor is greater than the second threshold value. | 04-16-2009 |
Ryosuke Ebinuma, Tokyo JP
| Patent application number | Description | Published |
|---|---|---|
| 20120104015 | PAPER SHEET RECEIVING/DISPENSING APPARATUS - A paper sheet receiving/dispensing apparatus includes strip films at least one of which is affixed, on at least one of front and back sides, with marks at intervals of a predetermined pattern in a predetermined shape and in a color different from a color of the strip films, a detection sensor for detecting the marks, and a storage device for storing a table that indicates an association between a roll outer diameter of the strip films wound around a winding drum and driving pulses of a stepping motor. The apparatus calculates the roll outer diameter based on the number of rotations of the winding drum, which is calculated based on detection pulses of the marks, and thicknesses of the strip films and a paper sheet, and controls rotations of the motor with driving pulses read from the table. | 05-03-2012 |
Ryosuke Ebinuma, Inagi JP
| Patent application number | Description | Published |
|---|---|---|
| 20110156335 | CONVEYING DIRECTION-SWITCHING DEVICE FOR PAPER LEAVES, CONVEYING DIRECTION CONTROL METHOD, AND PAPER LEAVES PROCESSOR - A conveying direction-switching device is formed by direction-changing drums each having the same hollow cylindrical shape having a length corresponding to a lateral width of paper money bills to be conveyed. The direction-changing drum has first to fourth openings arranged in the outer periphery thereof, in a manner spaced from each other by a rotational angle of 90 degrees, and the rotational angle position thereof is controlled to be a predetermined phase angle. Inside the direction-changing drum, the first opening and the fourth opening are connected by a paper money guide forming a first curved passage, the second opening and the fourth opening are connected by a paper money guide forming a straight passage, and the third opening and the fourth opening are connected by a paper money guide forming a second curved passage. | 06-30-2011 |
Shingo Ebinuma, Miyagi-Ken JP
| Patent application number | Description | Published |
|---|---|---|
| 20100321215 | COMPLEX-OPERATION INPUT DEVICE - A complex-operation input device having an operable knob held in a rotatable and slidable manner includes a rotation sensor that detects rotation of the operable knob on the basis of displacement of a second detected portion, and a slide sensor that detects sliding of the operable knob on the basis of displacement of a first detected portion. The direction in which the second detected portion moves with the sliding of the operable knob is substantially orthogonal to a rotation axis about which the operable knob rotates. The slide sensor is disposed such that, when the operable knob is slid, the slide sensor detects the sliding before the rotation sensor detects the displacement of the second detected portion. | 12-23-2010 |
Toshimitsu Ebinuma, Hiratsuka-Shi JP
| Patent application number | Description | Published |
|---|---|---|
| 20100205745 | AIR CELL - An object of the present invention is to provide an air cell which is capable of detecting that the upper end side and the lower end side of the air bag are nearer than a predetermined distance. | 08-19-2010 |
Toshimitsu Ebinuma, Hiratsuka JP
| Patent application number | Description | Published |
|---|---|---|
| 20080211650 | TIRE INFORMATION TRANSMITTER AND TIRE INFORMATION ACQUISITION SYSTEM USING THE TRANSMITTER - A tire information transmitter measures ambient information in a tire cavity region including at least pressure to wirelessly transmit to outside the tire cavity region. The tire transmitter comprises: a sensor unit having a pressure sensor for measuring a pressure in the tire cavity region; a control unit for comparing a level of a pressure signal representing pressure measured by the sensor unit with a threshold value and for generating an operation signal indicating that the tire information transmitter is operating; and a transmitting unit for wirelessly transmitting the pressure signal or the operation signal. The control unit controls the transmitting of the transmitting unit and compares the level of the pressure signal with the threshold value continually after a supply of driving power is started, and has a comparing mode in which the transmitting unit transmits the operation signal at a first time interval, and a transmitting mode in which the transmitting unit transmits the pressure signal at a second time interval which is shorter than the first time interval. Further, the control unit irreversibly shifts from the comparing mode to the transmitting mode, once the level of the pressure signal exceeds the threshold value, as a result of the comparing. | 09-04-2008 |
Toshimitsu Ebinuma, Kanagawa JP
| Patent application number | Description | Published |
|---|---|---|
| 20090102633 | TIRE INFORMATION TRANSMITTER, TIRE INFORMATION ACQUIRING SYSTEM, AND TIRE/WHEEL ASSEMBLY - A tire information transmitter is mounted in a tire cavity region surrounded by a tire inner circumference surface and a wheel wall surface and senses atmospheric information in the tire cavity region to wirelessly transmit to outside the tire cavity region. The transmitter has a sensor for sensing atmospheric information in the tire cavity region, a circuit board having a processing circuit for processing a sensed signal from the sensor and having a transmitting circuit for wirelessly transmitting a processed signal and a battery for supplying power for driving the circuits. The battery is made as an encapsulated body of a thin plate shape, having a thin plate surface, by encapsulating battery components with an insulation film, and the encapsulated body has an area ratio of the thin plate surface to a thickness of the thin plate shape of not less than 200 mm, and a mass of not more than 5 g. A tire information acquiring system has the transmitter and a receiver for receiving a signal from the transmitter. | 04-23-2009 |
| 20110041250 | AIR CELL CUSHION - This air cell cushion has a pair of side air cells extending upwardly from the upper surface side of the base member at both end sides in the lateral direction of the base member. The side air cells have a larger front-rear direction size than in the lateral direction thereof. Also, each side air cell is configured to inflate outward in the lateral direction. By this, in a case in which the side air cells face the armrests of the wheel chair, when the side air cells are inflated outward in the lateral direction, the outer side surfaces of the side air cells abut against or become adjacent to the armrests. | 02-24-2011 |
Yuta Ebinuma, Saitama JP
| Patent application number | Description | Published |
|---|---|---|
| 20100269405 | DIESEL FUEL COMPOSITION - Disclosed is a diesel fuel composition obtained by mixing a diesel oil and a biodiesel oil, which can be used in popular diesel cars. The diesel fuel composition enables remarkable reduction in sludge formation. Specifically disclosed is a diesel fuel composition obtained by mixing a diesel oil containing an aromatic component and a biodiesel oil. The diesel fuel composition is characterized in that the biodiesel oil content in the diesel fuel composition is 10-50% by volume, and the aromatic component content in the diesel oil is not less than 30% by volume. | 10-28-2010 |