Patent application number | Description | Published |
20120263677 | Combination of Local and Systemic Immunomodulative Therapies for Enhanced Treatment of Cancer - A method for the treatment of cancer comprising administration of a therapeutically effective amount of an intralesional chemoablative pharmaceutical composition, or variant of said composition, in combination with a therapeutically effective amount of a systemic immunomodulatory anticancer agent. A further method for the treatment of cancer comprising administration of a therapeutically effective amount of an intralesional chemoablative pharmaceutical composition, or variant of said composition, in combination with a therapeutically effective amount of a systemic targeted anticancer agent. The present invention is further directed to pharmaceutical compositions for treatment of cancer. The intralesional chemoablative pharmaceutical composition can comprise an IL chemoablative agent comprising primarily a halogenated xanthene. | 10-18-2012 |
20150290165 | Combination of Local and Systemic Immunomodulative Therapies for Enhanced Treatment of Cancer - A method for the treatment of cancer comprising administration of a therapeutically effective amount of an intralesional chemoablative pharmaceutical composition, or variant of said composition, in combination with a therapeutically effective amount of a systemic immunomodulatory anticancer agent. A further method for the treatment of cancer comprising administration of a therapeutically effective amount of an intralesional chemoablative pharmaceutical composition, or variant of said composition, in combination with a therapeutically effective amount of a systemic targeted anticancer agent. The present invention is further directed to pharmaceutical compositions for treatment of cancer. The intralesional chemoablative pharmaceutical composition can comprise an IL chemoablative agent comprising primarily a halogenated xanthene. | 10-15-2015 |
20150290318 | Combination of Local and Systemic Immunomodulative Therapies for Enhanced Treatment of Cancer - A method for the treatment of cancer comprising administration of a therapeutically effective amount of an intralesional chemoablative pharmaceutical composition, or variant of said composition, in combination with a therapeutically effective amount of a systemic immunomodulatory anticancer agent. A further method for the treatment of cancer comprising administration of a therapeutically effective amount of an intralesional chemoablative pharmaceutical composition, or variant of said composition, in combination with a therapeutically effective amount of a systemic targeted anticancer agent. The present invention is further directed to pharmaceutical compositions for treatment of cancer. The intralesional chemoablative pharmaceutical composition can comprise an IL chemoablative agent comprising primarily a halogenated xanthene. | 10-15-2015 |
Patent application number | Description | Published |
20080251202 | HEAT-RESISTANT STRUCTURAL EPOXY RESINS - Epoxy adhesive compositions containing a rubber-modified epoxy resin contain a bisphenol. The bisphenol can be pre-reacted with the rubber-modified epoxy resin to advance the resin. The adhesives are resistant to thermal degradation as can occur in so-called “overbake” conditions, in which the adhesive is heated to high temperatures for prolonged periods of time. In addition, expanded microballoons are included in epoxy structural adhesives to promote a desired fracture mode. | 10-16-2008 |
20120103517 | HEAT-RESISTANT STRUCTURAL EPOXY RESINS - Epoxy adhesive compositions containing a rubber-modified epoxy resin contain a bisphenol. The bisphenol can be pre-reacted with the rubber-modified epoxy resin to advance the resin. The adhesives are resistant to thermal degradation as can occur in so-called “overbake” conditions, in which the adhesive is heated to high temperatures for prolonged periods of time. In addition, expanded microballoons are included in epoxy structural adhesives to promote a desired fracture mode. | 05-03-2012 |
20130090431 | STORAGE-STABLE HEAT-ACTIVATED TERTIARY AMINE CATALYSTS FOR EPOXY RESINS - Epoxy adhesive compositions contain a heat-activatable catalyst. The heat-activatable catalyst includes a tertiary amine catalyst and a novolac resin that has a weight average molecular weight of at least 3000. One-component epoxy adhesive formulations that contain the heat-activatable catalyst have unexpectedly good storage stability. | 04-11-2013 |
20140171550 | EPOXY RESIN WITH ENHANCED VISCOSITY STABILITY AND USE THEREOF - The present invention provides low polyphenols (such as bisphenol A) tougheners for epoxy adhesives. The tougheners, and adhesives comprising the tougheners exhibit enhanced viscosity stability, e.g., compared to tougheners prepared from higher amounts of bisphenol A (and epoxy adhesives comprising them). | 06-19-2014 |
20150025176 | FLAME RETARDANT STRUCTURAL EPOXY RESIN ADHESIVES AND PROCESS FOR BONDING METAL MEMBERS - A heat-curable structural adhesive includes at least one non-rubber-modified epoxy resin; an optional rubber or toughener, one or more epoxy curing agents, one or more epoxy curing catalysts; and a flame retardant mixture that includes (i) alumina trihydrate, (ii) zinc borate and (iii) melamine or a melamine derivative. The structural adhesive is useful for bonding metals to other materials or metals to other metals. The structural adhesive strongly resists ignition when welding is performed in the presence of the uncured material, and does not interfere significantly with weld performance. | 01-22-2015 |
Patent application number | Description | Published |
20090034198 | APPARATUS AND METHOD FOR ATTACHING HEATSINKS - An apparatus for attaching a heatsink to an electronic module mounted on a circuit card assembly includes a load frame; a load arm having a first end being pivotally coupled to one end of the load frame and a second end configured to receive at least a portion of a load screw therethrough; a spring plate disposed at an opposite end of the one end of the load frame, and configured to threadedly receive the load screw, opposite ends of the spring plate being retained while an intermediate portion threadedly receiving the at least a portion of the load screw is allowed to bow upwards toward a bottom of the opposite end of the load arm; and a heatsink disposed on the module. An intermediate portion of the load arm aligned with a center region of the module biases the heatsink toward the module when the load screw is threadedly engaged with the spring plate. | 02-05-2009 |
20120106071 | FLUID COOLING SYSTEM AND ASSOCIATED FITTING ASSEMBLY FOR ELECTRONIC COMPONENT - A fluid cooling system and associated fitting assembly for an electronic component such as a multi-processor computer offer easy and reliable connect and disconnect operations while doing so in a minimum amount of available space without damaging associated components of an electronic device, computer or cooling system. One exemplary fitting assembly includes a manifold mount with a port that is in fluid communication with a manifold tube. A fitting is sized and configured to mate with the port and is in fluid communication with associated cooling tubes of a cold plate. A latch is pivotally mounted to the manifold mount for movement to and between a first position in which the latch secures the fitting to the manifold mount and a second position in which the fitting is capable of being disconnected from the manifold mount. | 05-03-2012 |
20120120605 | IN-LINE MEMORY AND CIRCUIT BOARD COOLING SYSTEM - A system to remove heat from an in-line memory module and/or circuit board may include a cold-rail to engage each end of an in-line memory module adjacent to where the in-line memory module is attachable to a circuit board, the cold-rail to remove heat from the in-line memory module. The system may also include a cold-plate connected to the cold-rail with the circuit board between the cold-plate and the cold-rail, the cold-plate to remove heat from the circuit board. | 05-17-2012 |
20120147563 | IMPLEMENTING LOADING AND HEAT REMOVAL FOR HUB MODULE ASSEMBLY - A method and apparatus are provided for implementing loading and heat removal for a hub module assembly. The hub module assembly includes a hub chip and a plurality of optical modules attached by land grid array (LGA) assembly disposed on a top surface metallurgy (TSM) LGA residing on a hub ceramic substrate. The ceramic substrate is connected to a circuit board through a bottom surface metallurgy (BSM) LGA assembly. A base alignment ring includes a plurality of alignment features for engaging the circuit board and locating an LGA interposer of the BSM LGA assembly. Each of a pair of top alignment rings includes cooperating alignment features for engaging and locating a respective LGA interposer of respective LGA sites of the TSM LGA assembly. The two LGA interposers of the TSM LGA assembly align, retain, and make the electrical connection between the optical modules and the hub chip. | 06-14-2012 |
20130188316 | FLUID COOLING SYSTEM AND ASSOCIATED FITTING ASSEMBLY FOR ELECTRONIC COMPONENT - A fluid cooling system and associated fitting assembly for an electronic component such as a multi-processor computer offer easy and reliable connect and disconnect operations while doing so in a minimum amount of available space without damaging associated components of an electronic device, computer or cooling system. One exemplary fitting assembly includes a manifold mount with a port that is in fluid communication with a manifold tube. A fitting is sized and configured to mate with the port and is in fluid communication with associated cooling tubes of a cold plate. A latch is pivotally mounted to the manifold mount for movement to and between a first position in which the latch secures the fitting to the manifold mount and a second position in which the fitting is capable of being disconnected from the manifold mount. | 07-25-2013 |
20140127915 | IMPLEMENTING CONNECTION OF TWO LARGE ELECTRONIC BOARDS UTILIZING LGA INTERCONNECT - A method and apparatus are provided for implementing electrical connection of two large circuit cards through multiple discrete land grid array (LGA) sites. Each of the circuit cards includes a plurality of LGA sites. A first circuit card includes a plurality of LGA interposers locally aligned at the respective LGA sites of the first circuit card. A board-to-board connection hardware assembly connecting a second circuit card to the first circuit card includes a elongated carrier defining a cavity receiving a plurality of load springs coupled to an associated bearing block for loading and maintaining flatness of the LGA sites. | 05-08-2014 |
20140268575 | IMPLEMENTING HEAT SINK LOADING HAVING MULTIPOINT LOADING WITH ACTUATION OUTBOARD OF HEATSINK FOOTPRINT - A method and apparatus are provided for implementing enhanced heat sink loading for cooling an electronic module having one or more semiconductor chips. The apparatus includes an electronic module having one or more semiconductor chips; a heat sink; a heat sink load bearing member further comprising raised points; a load spring passing through the heat sink, the load spring having a latch arm at a first end and a load screw at a second end actuating the load spring, the load spring when actuated is configured to bear against the raised points to equalize pressure distribution over one or more semiconductor chips on the electronic module. | 09-18-2014 |
Patent application number | Description | Published |
20130204719 | SYSTEMS AND METHODS FOR LICENSE PLATE RECOGNITION TO ENABLE ADVANCE ORDER PICKUP - An embodiment generally relates to systems and methods for processing orders associated with an establishment. In particular, a customer can submit a remote order for goods offered by the establishment, along with an associated license plate number of a vehicle that is to pick up the order. An image capture device can capture images of a vehicle on the premises of the establishment, and provide the images to a processing module which use automatic license plate recognition (ALPR) techniques to determine license plate data of the vehicle. The processing module can further examine an order list to determine if the license plate data is associated with an order on the order list, and, if so, add the order to a priority queue. | 08-08-2013 |
20130282420 | SYSTEMS AND METHODS FOR REALTIME OCCUPANCY DETECTION OF VEHICLES APPROACHING RETAIL SITE FOR PREDICTIVE ORDERING - Embodiments relate to systems and methods for realtime occupancy detection of vehicles approaching a retail site for predictive ordering. A restaurant or other retail site can maintain access areas, such as a drive through lane or parking area, which vehicles can approach to order food or other items. A set of sensors can detect the vehicles, and estimate the number of occupants in those vehicles. Detection techniques can include face detection technology, seat detection technology, thermal imaging, or others. The number of occupants can be estimated and sent to a production management engine monitoring the site. That engine can responsively issue production instructions, such as a number and type of food items to prepare, and when. By integrating an operational model of the site, including projected order amounts and types, with the realtime occupant count, more accurate matching of food or other production to customer demand can be achieved. | 10-24-2013 |
Patent application number | Description | Published |
20110068061 | Integrated Measurement System For Use with Surgical Fluid Salvage Containers - A reservoir for use with a blood collection system includes a housing, a pre-filter, and a spring mechanism. The housing defines a cavity and has an inlet for receiving fluid from a source. The pre-filter is located within the cavity, removes particulates contained within the fluid, and allows the fluid to pass through the pre-filter. The spring mechanism is connected to the pre-filter and allows the pre-filter to travel within the cavity as the pre-filter collects particulates. | 03-24-2011 |
20120168377 | Integrated Measurement System for Use with Surgical Fluid Salvage Containers - A reservoir for use with a blood collection system includes a housing, a pre-filter, and a spring mechanism. The housing defines a cavity and has an inlet for receiving fluid from a source. The pre-filter is located within the cavity, removes particulates contained within the fluid, and allows the fluid to pass through the pre-filter. The spring mechanism is connected to the pre-filter and allows the pre-filter to travel within the cavity as the pre-filter collects particulates. | 07-05-2012 |
20130314047 | LOW-POWER BATTERY PACK WITH SAFETY SYSTEM - The present application is directed toward a method and system for conserving battery power in low power systems. According to one aspect of the invention, a battery with a low power processor is used to shut off the monitor circuit that determines the charge remaining on a battery. Periodically, the low power processor will wake-up and power on the monitor circuit to determine the remaining charge of the battery. According to another aspect of the invention, there is a safety override circuit. The safety override circuit is a fail-safe that allows charge to flow from the battery when there is a fault with the low power processor, for example if the low power processor fails to wake-up. | 11-28-2013 |
Patent application number | Description | Published |
20120029963 | Automated Management of Tasks and Workers in a Distributed Workforce - A job is divided into multiple discrete tasks that can be performed by multiple different workers of a distributed workforce. The tasks are assigned to the workers through their mobile phones or other communication devices, and the workers perform the assigned tasks and provide responses to the tasks through the devices. Workers are compensated, in part, based in part on the quality of their responses. Once the workers' responses have been determined to be sufficiently accurate, the responses are assembled into a final result. To manage the distributed workforce, the system stores information for each worker, such as an identification of the worker, the tasks previously completed by the worker, and the quality of performance of those tasks. The stored worker information is used to assign tasks to workers, to compensate workers, and in general to manage the workforce. | 02-02-2012 |
20120029978 | Economic Rewards for the Performance of Tasks by a Distributed Workforce - A job is divided into multiple discrete tasks that can be performed by multiple different workers of a distributed workforce. The tasks are assigned to the workers through their mobile phones or other communication devices, and the workers perform the assigned tasks and provide responses to the tasks through the devices. Workers are compensated, in part, based in part on the quality of their responses. Once the workers' responses have been determined to be sufficiently accurate, the responses are assembled into a final result. To manage the distributed workforce, the system stores information for each worker, such as an identification of the worker, the tasks previously completed by the worker, and the quality of performance of those tasks. The stored worker information is used to assign tasks to workers, to compensate workers, and in general to manage the workforce. | 02-02-2012 |
20120265574 | CREATING INCENTIVE HIERARCHIES TO ENABLE GROUPS TO ACCOMPLISH GOALS - A job is divided into tasks belonging to various levels in a hierarchy such that the tasks of one level of the hierarchy depend on the performance of the tasks of another level. The divided tasks are assigned to the respondents and, once the respondents' responses have been determined to be sufficiently accurate, the responses are assembled into a final result. The respondents may be rewarded for completion of their assigned tasks, and the rewards may be structured such that the rewards for the completed tasks create an informal hierarchy amongst the respondents. | 10-18-2012 |
20120265578 | COMPLETING TASKS INVOLVING CONFIDENTIAL INFORMATION BY DISTRIBUTED PEOPLE IN AN UNSECURE ENVIRONMENT - A system receives from a client a job comprising confidential information. The system then distorts the confidential information associated with the job. Next, the system divides the job into multiple discrete tasks such that the distorted confidential information is further divided and the confidential information cannot be deciphered from an individual task. The tasks are then delegated to respondents in different geographical locations with different social preferences. Because of these differences the respondents are unlikely to communicate information about their job with each other. The respondents receive the job securely through their electronic devices, perform the delegated tasks, and provide the system with responses to the tasks through the devices. The system receives the responses for individual tasks, deduces a unified job response from the received responses and transmits the unified response to the client. | 10-18-2012 |
20140351038 | Distribution and Redemption of Coupons Targeted to Mobile Devices - A system and a method for distributing and redeeming coupons through mobile devices of consumers are disclosed. Consumers submit a coupon and purchase proof to the redemption server through mobile devices. Once the purchase information is confirmed, a reward is granted to the consumers along with a survey with questions about consumer demographic information and product related questions. The consumers' answers to the survey questions help target the future coupon distributions. | 11-27-2014 |
Patent application number | Description | Published |
20110190572 | Methods and Compositions for Vein Harvest and Autografting - The leading cause of graft failure is the subsequent development of intimal hyperplasia, which represents a response to injury that is thought to involve smooth muscle proliferation, migration, phenotypic modulation, and extracellular matrix (ECM) deposition. Surgical techniques typically employed for vein harvest—stretching the vein, placing the vein in low pH, solutions, and the use of toxic surgical skin markers—are shown here to cause injury. The invention therefore provides for non-toxic surgical markers than also protect against stretch-induced loss of functional viability, along with other additives. Devices and compositions for reducing physical stress or protecting from the effects flowing therefrom, also are provided. | 08-04-2011 |
20140220547 | Methods and Compositions for Vein Harvest and Autografting - The leading cause of graft failure is the subsequent development of intimal hyperplasia, which represents a response to injury that is thought to involve smooth muscle proliferation, migration, phenotypic modulation, and extracellular matrix (ECM) deposition. Surgical techniques typically employed for vein harvest—stretching the vein, placing the vein in low pH, solutions, and the use of toxic surgical skin markers—are shown here to cause injury. The invention therefore provides for non-toxic surgical markers than also protect against stretch-induced loss of functional viability, along with other additives. Devices and compositions for reducing physical stress or protecting from the effects flowing therefrom, also are provided. | 08-07-2014 |