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Dwyer, NJ

Edward Dwyer, Pittsgrove, NJ US

Patent application numberDescriptionPublished
20110264152Insertion Tool Assembly - Insertion tool assemblies for positioning an implant at a target location in a patient. Insertion tool assemblies that comprise first and second jaw portions configured to engage an implant; a sleeve assembly coupled to the first and second jaw portions; and a handle coupled to the sleeve assembly.10-27-2011
20120010653Soft Tissue Repair System - A soft tissue repair system is provided for covering or filling openings in the annulus of an intervertebral disc. The soft tissue repair system uses a single plug or a combination of a first plug and a second plug. The second plug is a flowable plug such as an adhesive material or a material that hardens to a flexible plug material. Each plug is configured to close the opening in the annulus and can be positioned within the opening, over the opening at the exterior surface or over the opening at the interior surface. The plug can also be combined with a clamping mechanism that engages the annulus to secure the plug in the opening.01-12-2012

James Ryan Dwyer, Nashanic Station, NJ US

Patent application numberDescriptionPublished
20100063592INTERLOCKING MULTI-PIECE INTERVERTEBRAL DISC PROSTHESIS AND METHOD FOR IMPLANTING SAME - An interlocking intervertebral disc prosthesis is provided. The prosthesis can include a left prosthetic body and a right prosthetic body that interlock with one another. A kit for replacing an intervertebral disc with an interlocking intervertebral disc prosthesis is also provided. A method for surgically implanting an interlocking intervertebral disc prosthesis is also provided.03-11-2010

James W. Dwyer, Neshanic Station, NJ US

Patent application numberDescriptionPublished
20100241166Interspinous Internal Fixation/Distraction Device - Disclosed are an apparatus for an interspinous fixation and/or distraction of vertebrae and a methodology for minimally invasive implantation of the apparatus in the spine of a patient. The apparatus corresponds to a pair of teardrop shaped lateral wing elements spaced apart by a central core element that may be selectively sized during the implantation process. The wings and central core are held together by a single threaded bolt and locking nut configuration resulting in a simple structure that may be easily implanted with minimal patient discomfort.09-23-2010

James William Dwyer, Nashanic Station, NJ US

Patent application numberDescriptionPublished
20100063592INTERLOCKING MULTI-PIECE INTERVERTEBRAL DISC PROSTHESIS AND METHOD FOR IMPLANTING SAME - An interlocking intervertebral disc prosthesis is provided. The prosthesis can include a left prosthetic body and a right prosthetic body that interlock with one another. A kit for replacing an intervertebral disc with an interlocking intervertebral disc prosthesis is also provided. A method for surgically implanting an interlocking intervertebral disc prosthesis is also provided.03-11-2010

Michael Dwyer, Scoth Plains, NJ US

Patent application numberDescriptionPublished
201201360164, 5, 6-TRISUBSTITUTED PYRIMIDINE DERIVATIVES AS FACTOR IXA INHIBITORS - The present invention relates to novel heterocyclic compounds of Formulae (I): (Chemical formula should be inserted here as it appears on abstract in paper form) Formula (I) as disclosed herein, or a pharmaceutically acceptable salt, solvate, ester, prodrug or stereoisomer thereof. Also disclosed are pharmaceutical compositions comprising said compounds, and methods for using said compounds for treating or preventing a thromboembolic disorder.05-31-2012

Michael Dwyer, Scotch Plains, NJ US

Patent application numberDescriptionPublished
20080279822Crystalline Polymorphs of a CXC-Chemokine Receptor Ligand - The present invention relates to four distinct crystalline polymorphs of a monohydrate of Compound A having the following chemical structure:11-13-2008
200903060793,4-DI-SUBSTITUTED CYCLOBUTENE-1,2-DIONES AS CXC-CHEMOKINE RECEPTOR LIGANDS - There are disclosed compounds of the formula12-10-2009
20110059958MORPHOLINONE COMPOUNDS AS FACTOR IXA INHIBITORS - The present invention provides a compound of Formula (I)03-10-2011
20110135650MORPHOLINONE COMPOUNDS AS FACTOR IXA INHIBITORS - The present invention provides a compound of Formula (I)06-09-2011
201102130293,4-Di-Substituted Cyclobutene-1,2-Diones as CXC-Chemokine Receptor Ligands - There are disclosed compounds of the formula09-01-2011

Patent applications by Michael Dwyer, Scotch Plains, NJ US

Michael P. Dwyer, Scotch Plains, NJ US

Patent application numberDescriptionPublished
20100125068METHODS FOR INHIBITING PROTEIN KINASES - The present invention provides methods for inhibiting protein kinases selected from the group consisting of AKT, Checkpoint kinase, Aurora kinase, Pim kinases, and tyrosine kinase using pyrazolo[1,5-a]pyrimidine compounds and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with protein kinases using such compounds.05-20-2010
201001304652-AMINOTHIAZOLE-4-CARBOXYLIC AMIDES AS PROTEIN KINASE INHIBITORS - The present invention relates to novel Anilinopiperazine Derivatives of formula (I), compositions comprising the Anilinopiperazine Derivatives, and methods for using the Anilinopiperazine Derivatives for treating or preventing a proliferative disorder, an anti-proliferative disorder, inflammation, arthritis, a central nervous system disorder, a cardiovascular disease, alopecia, a neuronal disease, an ischemic injury, a viral disease, a fungal infection, or a disorder related to the activity of a protein kinase.05-27-2010
20110183933NOVEL MODULATORS OF CELL CYCLE CHECKPOINTS AND THEIR USE IN COMBINATION WITH CHECKPOINT KINASE INHIBITORS - In its many embodiments, the present invention provides a novel class of pyrimidine analogs of formula (V) as targeted mechanism-based modulators of cell cycle checkpoints. Cancers and/or malignancies can be treated by administration of a cell cycle checkpoint modulator of the invention. Also discussed are suitable combinations of the cell cycle checkpoint modulator with a checkpoint kinase inhibitor to produce synergistic apoptosis in cancer cells. The invention includes methods of treating cancers by administering the combination of the cell cycle checkpoint modulator and the checkpoint kinase inhibitor, pharmaceutical compositions comprising the activator as well as the combination and pharmaceutical kits.07-28-2011
20120029204SYNTHESIS OF SUBSTITUTED-3-AMINOPYRAZOLES - The present invention discloses a process of preparing compound of formula (I): wherein A, M, and Z are as defined herein. An example of a compound of formula (I) is 3-amino-1-methyl-1H-1′H-4,4′-bispyrazole.02-02-2012

Patent applications by Michael P. Dwyer, Scotch Plains, NJ US

Tracey Dwyer, Wayne, NJ US

Patent application numberDescriptionPublished
20110287770Methods of determining coverage areas - A method of determining coverage areas in a communication system includes determining, by a controller, a plurality of base stations in the communication system and determining, by the controller, a Voronoi region for each of the plurality of base stations. The Voronoi region corresponds to the coverage area for the base station. Each location in the Voronoi region is closest to the base station than any other base station of the plurality of base stations.11-24-2011

William J. Dwyer, Hazlet, NJ US

Patent application numberDescriptionPublished
20080281296Universal valve for Foley type urinary catheter - A universal valve for the Foley type urinary catheter has structure which permits its use as a patient controlled drainage valve, as an interface from which to take sterile samples, and as a connection to a day or night collection bag all without removal of the universal valve from the Foley type urinary catheter. The universal valve may be open or closed by the use of a squeeze mechanism for patient control, or by movement of the threaded connection between the universal valve and a collection bag so that the universal valve is continuously open for drainage into the urine collection bag.11-13-2008