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Dwek

David Dwek, London GB

Patent application numberDescriptionPublished
20100116726EFFLUENT DISCHARGE - Apparatus for discharging effluent from a sea-based vessel (05-13-2010

Ramond Allen Dwek, Oxford GB

Patent application numberDescriptionPublished
20110045021SUGAR IMMUNOGENS - Disclosed are compositions and methods useful for inducing an immunogenic response in a subject or host. In particular, the compositions and methods may be directed to carbohydrate HIV vaccines and to methods of producing a carbohydrate HIV vaccine by introducing antigenic sugars into mimics of the glycans of the HIV envelope glycoproteins gp120 and gp41.02-24-2011

Raymond Dwek, Oxford GB

Patent application numberDescriptionPublished
20080280972Iminosugar treatment of tumors - A proliferation of cells can be reduced by contacting the cells with a compound having formula (I)11-13-2008
20090041776Production of cancer-specific antibodies in plants - The invention as described herein provides compositions and methods for cancer immunotherapy and cancer detection. In particular, the invention discloses plant-derived human monoclonal antibodies that bind human carcinoma antigens in cancer cell lines.02-12-2009
20100266678CHOLESTEROL LEVEL LOWERING LIPOSOMES - Provided are methods of reducing cellular cholesterol levels using lipid particles that are capable of cellular entry. Such lipid particles may be used for treating or preventing a disease or condition that is caused by or associated with an increased cellular cholesterol level and for treating or preventing a disease or condition, that is caused by or associated with a virus, that relies on cellular cholesterol for its replication.10-21-2010
20110136868AGENTS FOR INHIBITING OSTEOCLASTOGENESIS AND/OR OSTEOCLAST ACTIVATION - Agents, which are both ceramide glucosyltransferase inhibitors and glucosidase inhibitors, may inhibit osteoclastogenesis and/or reduce osteoclast activation and, therefore, may be useful for osteolytic activity and bone loss in subjects with conditions, such as multiple myeloma.06-09-2011
20110143351GLYOSYLATION MARKERS FOR CANCER AND CHRONIC INFLAMMATION - The present invention provides novel biomarkers for use in the diagnosis and prognosis of cancerous and malignant conditions and further of diseases which are mediated by a proinflammatory immune response. The biomarkers are glycoproteins, the levels of expression of which have been correlated by the inventors to correspond to particular disease conditions. The invention further extends to methods for use in monitoring the response to therapy of a treatment for use in the treatment of a cancerous condition or proinflammatory disease.06-16-2011

Patent applications by Raymond Dwek, Oxford GB

Raymond A. Dwek, Oxfordshire GB

Patent application numberDescriptionPublished
20100137365Long chain N-alkyl compounds and oxa-derivatives thereof - Long chain N-alkyl amino and imino compounds, oxa-substituted derivatives thereof, and pharmaceutical compositions including such compounds are described. The long chain N-alkyl group is a C06-03-2010

Raymond Allen Dwek, Oxford GB

Patent application numberDescriptionPublished
20090252785ENDOPLASMIC RETICULUM TARGETING LIPOSOMES - Provided are compositions that include lipid particles, such as liposomes, that can fuse with the ER membrane of a cell. The lipid particles can also deliver a cargo, such as a therapeutic or an imaging agent, encapsulated inside the particles inside the ER lumen of the cell. The compositions can be useful for treating and/or preventing diseases or conditions caused by or associated with a virus, such as viral infections, including HIV and HCV infections.10-08-2009