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| 20090146803 | Monitoring and Notification Apparatus - The disclosure relates to monitoring and notification apparatus capable of monitoring events at various locations. The apparatus includes a sound receiving unit which receives audio content from various locations. A user can select which of the location is monitored at any one time. In one embodiment, this selection is made depending on the orientation of the sound receiving unit. | 06-11-2009 |
| 20090147649 | Sound Playback and Editing Through Physical Interaction - The disclosure relates to sound playback and editing apparatus. The editing apparatus uses user interaction to allow the user to instinctively modify recorded sound. This can be achieved by converting a quality of the user's physical interactions with the editing apparatus into instructions for processing the sound. For example, in one embodiment the user can mix sound files by ‘mixing’, i.e. shaking, physical representations of those sound files (such as the recording medium on which the files are stored) alone or together. | 06-11-2009 |
| 20090180623 | Communication Devices - The disclosure relates to communication devices which monitor an audio environment at a remote location and convey to a user a representation of that audio environment. The “representation” may be an abstraction of the audio environment at the remote location or may be a measure of decibels or some other quality or parameter of the audio environment. In some embodiments, the communication devices are two-way devices which allow users at remote locations to share an audio environment. In some embodiments, the communication devices are one way devices. In some embodiments, the communication devices may have the form of a window and be arranged to present sound in a manner that mimics sound received through a window. In such embodiments, the more open the window is, the more sound is relayed by the communication device. | 07-16-2009 |
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| 20100035283 | Preparation Method - A method of performing an immunologic evaluation of a subject, comprising collecting a whole blood sample from the subject, maintaining the sample for at least 6 hours after the collection, purifying a population of cells comprising lymphocytes and antigen presenting cells from the maintained sample, optionally by a process incorporating a positive or negative affinity selection step, and using the purified cells in a cell-mediated immunoassay (CMI assay). | 02-11-2010 |
| 20110201031 | PREPARATION METHOD - A method of performing an immunologic evaluation of a subject, comprising collecting a whole blood sample from the subject, maintaining the sample for at least 6 hours after collection, purifying a population of cells comprising lymphocytes and antigen presenting cells from the maintained sample, optionally by a process incorporating a positive or negative affinity selection step to remove granulocytes, and using the purified cells in a cell-mediated immunoassay (CMI assay). | 08-18-2011 |
| 20120028277 | PREPARATION METHOD - A method of performing an immunologic evaluation of a subject, comprising collecting a whole blood sample from the subject, maintaining the sample for at least 6 hours after collection, purifying a population of cells comprising lymphocytes and antigen presenting cells from the maintained sample, optionally by a process incorporating a positive or negative affinity selection step to remove granulocytes, and using the purified cells in a cell-mediated immunoassay (CMI assay). | 02-02-2012 |
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| 20080260735 | Transfer request (37 CFR 1.821(e)) humanised antibodies to the epidermal growth factor receptor - The present invention provides a humanised form of the antibody 340 obtainable from the cell line deposited with the ECACC under accession number 97021428. Such antibodies have been found to have an increased ability to kill cells compared to the murine antibody 340. Also provided are nucleic acids encoding such antibodies, as well as the use of the antibodies in medicine, in particular in the treatment of cancer. | 10-23-2008 |
| 20090281285 | BINDING MEMBER WHICH BINDS TO BOTH LEWIS-Y AND LEWIS-B HAPTENS, AND ITS USE FOR TREATING CANCER - The invention relates to the use of a binding member which binds to Lewis | 11-12-2009 |
| 20100040620 | ANTI-CANCER ANTIBODIES AGAINST LEWISy AND LEWISb ANTIGENS - The present invention provides a binding complex comprising antibodies or antigen-binding fragments which bind to both Lewis | 02-18-2010 |
| 20100260806 | NUCLEIC ACIDS - The present invention provides a nucleic acid which comprises a non-specific promoter and at least one sequence that encodes a polypeptide that has at least one heterologous T cell epitope therein but does not have any regulatory T cell epitopes. The polypeptide may be one chain of a heterodimer, the heterologous T cell epitope causing disruption of the heterodimer chain such that it cannot bind with the other chain of the heterodimer. The nucleic acid can be used to raise a T cell response against the at least one heterologous T cell epitope. | 10-14-2010 |
| 20110150906 | BINDING MEMBER WHICH BINDS TO BOTH LEWIS-Y AND LEWIS-B HAPTENS, AND ITS USE FOR TREATING CANCER - The invention relates to the use of a binding member which binds to Lewis | 06-23-2011 |
| 20110165180 | Polypeptides capable of binding to CD64 comprising one or more heterologous T cell epitopes and their uses - The invention relates to the use of a polypeptide that comprises i) a first portion comprising the part of human Fc that binds to CD64, and ii) a second portion comprising one or more heterologous T cell epitopes for stimulating a cytotoxic T cell response. The polypeptide may be an antibody that may be used to stimulate a cytotoxic T cell response against pathogens and tumour cells in patients in need of such treatment. | 07-07-2011 |
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| 20090093416 | CASPASE INHIBITORS AND USES THEREOF - The present invention provides a compound of formula I: | 04-09-2009 |
| 20090281082 | COMPOUNDS USEFUL AS PROTEIN KINASE INHIBITORS - The present invention relates to compounds useful as inhibitors of protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions. | 11-12-2009 |
| 20090286840 | Thiophene-carboxamides useful as inhibitors of protein kinases - The present invention relates to compounds useful as inhibitors of protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions. | 11-19-2009 |
| 20100105914 | CASPASE INHIBITORS AND USES THEREOF - The present invention provides a compound of formula I: | 04-29-2010 |
| 20100222318 | COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE - The present invention relates to pyrazine compounds useful as inhibitors of ATR protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and methods of using the compounds in in vitro applications, such as the study of kinases in biological and pathological phenomena; the study of intracellular signal transduction pathways mediated by such kinases; and the comparative evaluation of new kinase inhibitors. | 09-02-2010 |
| 20110137037 | CASPASE INHIBITOR PRODRUGS - This invention relates to prodrugs of caspase inhibitors comprising of a furo[3,2-d]oxazolin-5-one moiety which, under specific conditions, can convert into biologically active compounds, particularly caspase inhibitors. | 06-09-2011 |
| 20110178146 | THIOPHENE-CARBOXAMIDES USEFUL AS INHIBITORS OF PROTEIN KINASES - The present invention relates to compounds useful as inhibitors of protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions. | 07-21-2011 |
| 20110190507 | THIOPHENE-CARBOXAMIDES USEFUL AS INHIBITORS OF PROTEIN KINASES - The present invention relates to compounds useful as inhibitors of protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising said compounds and methods of using the compounds and compositions in the treatment of various disease, conditions, or disorders. The invention also relates to processes for preparing compounds of the inventions. | 08-04-2011 |
| 20120010197 | PROTEIN KINASE INHIBITORS - In one aspect, the invention provides compounds of Formula I | 01-12-2012 |
| 20120028965 | COMPOUNDS USEFUL AS PROTEIN KINASE INHIBITORS - The present invention relates to compounds useful as inhibitors of protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions. | 02-02-2012 |
