Dunia
Dunia Hernández Inguanzo, La Habana CU
Patent application number | Description | Published |
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20120308615 | FORMULATION OF HEPATITIS B VIRUS ANTIGENS FOR CELLULAR STIMULATION FOLLOWED BY THERAPEUTIC IMMUNIZATION - The present invention is related with the field of the therapeutic immunization, specifically with the employment of a new formulation of antigens of the Hepatitis B Virus (HBV) for the cellular stimulation. The formulation is formed by the surface antigens (HBsAg) precipitated in suspension and the nucleocapsid (HBcAg) of the HBV. The formulation contains these antigens like suspended particles of sizes less than 500 nm and higher than 500 nm, in a mixture where the proportion among the particles of the mentioned sizes is among 50%-50% and 80%-20%, respectively. The selection of a range of sizes of particles allows that the levels of stimulation of several cellular types are maximized. Additionally, a cellular stimulation method is described with this formulation, and the later passive immunization of patients with chronic Hepatitis B, based on the maximum stimulation in vivo or in vitro using heterologous or autologous cells (dendritic cells, B cells and macrophages). The cells stimulated with this formulation are transferred to patients chronically infected with the HBV. | 12-06-2012 |
Dunia Hernández Inguanzo, La Habana CU
Patent application number | Description | Published |
---|---|---|
20120308615 | FORMULATION OF HEPATITIS B VIRUS ANTIGENS FOR CELLULAR STIMULATION FOLLOWED BY THERAPEUTIC IMMUNIZATION - The present invention is related with the field of the therapeutic immunization, specifically with the employment of a new formulation of antigens of the Hepatitis B Virus (HBV) for the cellular stimulation. The formulation is formed by the surface antigens (HBsAg) precipitated in suspension and the nucleocapsid (HBcAg) of the HBV. The formulation contains these antigens like suspended particles of sizes less than 500 nm and higher than 500 nm, in a mixture where the proportion among the particles of the mentioned sizes is among 50%-50% and 80%-20%, respectively. The selection of a range of sizes of particles allows that the levels of stimulation of several cellular types are maximized. Additionally, a cellular stimulation method is described with this formulation, and the later passive immunization of patients with chronic Hepatitis B, based on the maximum stimulation in vivo or in vitro using heterologous or autologous cells (dendritic cells, B cells and macrophages). The cells stimulated with this formulation are transferred to patients chronically infected with the HBV. | 12-06-2012 |
Dunia Prieto Francia, Madrid ES
Patent application number | Description | Published |
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20130330082 | Frame Structure For Adaptive Data Communications Over A Plastic Optical Fibre - The present invention relates to transmission and reception of data over a plastic optical fibre. In particular, the present invention provides for transmission and reception over the plastic optical fibre a particularly suitable frame structure. The frame structure includes a synchronization sequence and portions of user data alternating with alternating reference signal portions and control data portions. The length of the user data portions may be equal, the length of the synchronization sequence and the control data and reference signal portions may also be equal. The distances between the synchronization sequence and the reference signal portions and the control data portions are advantageously equal. The alternating of data and additional information avoids data decoding latency while maintaining the rate necessary for the additional information. | 12-12-2013 |