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Duncan, GB
Alexander Robert Duncan, Carton GB
| Patent application number | Description | Published |
|---|---|---|
| 20090311241 | Human antibodies that bind human IL-12 and methods for producing - Human antibodies, preferably recombinant human antibodies, that specifically bind to human interleukin-12 (hIL-12) are disclosed. Preferred antibodies have high affinity for hIL-12 and neutralize hIL-12 activity in vitro and in vivo. An antibody of the invention can be a full-length antibody or an antigen-binding portion thereof. The antibodies, or antibody portions, of the invention are useful for detecting hIL-12 and for inhibiting hIL-12 activity, e.g., in a human subject suffering from a disorder in which hIL-12 activity is detrimental. Nucleic acids, vectors and host cells for expressing the recombinant human antibodies of the invention, and methods of synthesizing the recombinant human antibodies, are also encompassed by the invention. | 12-17-2009 |
Alexander R. Duncan, Girton GB
| Patent application number | Description | Published |
|---|---|---|
| 20110008364 | ANTIBODIES TO TGF-BETA - The present invention relates to antibody molecules, in particular antibody molecules that bind Transforming Growth Factor beta (TGFβ), and uses thereof. More particularly, the invention relates to antibody molecules that bind and preferably neutralise TGFβ1, TGFβ2 and TGFβ3, so-called “pan-specific” antibody molecules, and uses of such antibody molecules. Preferred embodiments within the present invention are antibody molecules, whether whole antibody (e.g. IgG, such as IgG1 or IgG4) or antibody fragments (e.g. scFv, Fab, dAb). | 01-13-2011 |
Alexander Robert Duncan, Little Shelford GB
| Patent application number | Description | Published |
|---|---|---|
| 20100104563 | ANTIBODIES THAT BIND IL-18 AND METHODS OF INHIBITING IL-18 ACTIVITY - Antibodies that bind human interleukin-18 (hIL-18) are provided, in particular antibodies that bind epitope(s) of human IL-18. The antibodies can be, for example, entirely human antibodies, recombinant antibodies, or monoclonal antibodies. Preferred antibodies have high affinity for hIL-18 and neutralize hIL-18 activity in vitro and in vivo. An antibody of the invention can be a full-length antibody or an antigen-binding portion thereof. Method of making and method of using the antibodies of the invention are also provided. The antibodies, or antibody portions, of the invention are useful for detecting hIL-18 and for inhibiting hIL-18 activity, e.g., in a human subject suffering from a disorder in which hIL-18 activity is detrimental. | 04-29-2010 |
| 20110008357 | ANTIBODIES THAT BIND IL-18 AND METHODS OF INHIBITING IL-18 ACTIVITY - Antibodies that bind human interleukin-18 (hIL-18) are provided, in particular antibodies that bind epitope(s) of human IL-18. The antibodies can be, for example, entirely human antibodies, recombinant antibodies, or monoclonal antibodies. Preferred antibodies have high affinity for hIL-18 and neutralize hIL-18 activity in vitro and in vivo. An antibody of the invention can be a full-length antibody or an antigen-binding portion thereof. Method of making and method of using the antibodies of the invention are also provided. The antibodies, or antibody portions, of the invention are useful for detecting hIL-18 and for inhibiting hIL-18 activity, e.g., in a human subject suffering from a disorder in which hIL-18 activity is detrimental. | 01-13-2011 |
Alexander Robert Duncan, Cambridge GB
| Patent application number | Description | Published |
|---|---|---|
| 20080305114 | HUMAN ANTIBODIES THAT BIND HUMAN IL-12 AND METHODS FOR PRODUCING - Human antibodies, preferably recombinant human antibodies, that specifically bind to human interleukin-12 (hIL-12) are disclosed. Preferred antibodies have high affinity for hIL-12 and neutralize hIL-12 activity in vitro and in vivo. An antibody of the invention can be a full-length antibody or an antigen-binding portion thereof. The antibodies, or antibody portions, of the invention are useful for detecting hIL-12 and for inhibiting hIL-12 activity, e.g., in a human subject suffering from a disorder in which hIL-12 activity is detrimental. Nucleic acids, vectors and host cells for expressing the recombinant human antibodies of the invention, and methods of synthesizing the recombinant human antibodies, are also encompassed by the invention. | 12-11-2008 |
| 20090175857 | Human Antibodies That Bind Human IL-12 And Methods For Producing - Human antibodies, preferably recombinant human antibodies, that specifically bind to human interleukin-12 (hIL-12) are disclosed. Preferred antibodies have high affinity for hIL-12 and neutralize hIL-12 activity in vitro and in vivo. An antibody of the invention can be a full-length antibody or an antigen-binding portion thereof. The antibodies, or antibody portions, of the invention are useful for detecting hIL-12 and for inhibiting hIL-12 activity, e.g., in a human subject suffering from a disorder in which hIL-12 activity is detrimental. Nucleic acids, vectors and host cells for expressing the recombinant human antibodies of the invention, and methods of synthesizing the recombinant human antibodies, are also encompassed by the invention. | 07-09-2009 |
| 20090269302 | HUMAN ANTIBODIES THAT BIND HUMAN IL-12 AND METHODS FOR PRODUCING - Human antibodies, preferably recombinant human antibodies, that specifically bind to human interleukin-12 (hIL-12) are disclosed. Preferred antibodies have high affinity for hIL-12 and neutralize hIL-12 activity in vitro and in vivo. An antibody of the invention can be a full-length antibody or an antigen-binding portion thereof. The antibodies, or antibody portions, of the invention are useful for detecting hIL-12 and for inhibiting hIL-12 activity, e.g., in a human subject suffering from a disorder in which hIL-12 activity is detrimental. Nucleic acids, vectors and host cells for expressing the recombinant human antibodies of the invention, and methods of synthesizing the recombinant human antibodies, are also encompassed by the invention. | 10-29-2009 |
| 20110123544 | HUMAN ANTIBODIES THAT BIND HUMAN IL-12 AND METHODS FOR PRODUCING - Human antibodies, preferably recombinant human antibodies, that specifically bind to human interleukin-12 (hIL-12) are disclosed. Preferred antibodies have high affinity for hIL-12 and neutralize hIL-12 activity in vitro and in vivo. An antibody of the invention can be a full-length antibody or an antigen-binding portion thereof. The antibodies, or antibody portions, of the invention are useful for detecting hIL-12 and for inhibiting hIL-12 activity, e.g., in a human subject suffering from a disorder in which hIL-12 activity is detrimental. Nucleic acids, vectors and host cells for expressing the recombinant human antibodies of the invention, and methods of synthesizing the recombinant human antibodies, are also encompassed by the invention. | 05-26-2011 |
Blair C. Duncan, Aberdeen GB
| Patent application number | Description | Published |
|---|---|---|
| 20100147531 | Downhole tools - A fluid operated apparatus in the form of a flow cap, is mounted on an end of a downhole tool or sub, which itself has a screw thread fitting to a further tool, sub or tubular. The cap provides a number of fluid flow channels arranged in a spiral pattern upon the outer surface. The handedness of the channels matches the handedness of the screw thread fitting so that fluid flow from ports in the tool or sub, acts to tighten the screw thread fitting. A water injection valve including a flow cap is described. | 06-17-2010 |
Bruce Duncan, Reading/berkshire GB
| Patent application number | Description | Published |
|---|---|---|
| 20080252416 | Electronic Device - The present invention relates to an electronic device ( | 10-16-2008 |
Bruce Duncan, Reading GB
| Patent application number | Description | Published |
|---|---|---|
| 20080235198 | Translation Service for a System with a Content Directory Service - A system includes a device (MS-a) which stores media content information using a form of Content Directory Service (CDS) and querying devices (CP-a) which make queries for media content information. An entity ( | 09-25-2008 |
Christopher Robert Duncan, Chard GB
| Patent application number | Description | Published |
|---|---|---|
| 20110239399 | Vacuum Cleaner and Filter Bag Insert for a Vacuum Cleaner - The present invention relates to the field of vacuum cleaners and relates in particular to domestic or commercial cleaners which are provided with a bin (or vacuum chamber), rather than a filter bag, to collect air-entrained detritus. According to one aspect of the invention there is provided an insert ( | 10-06-2011 |
| 20110265283 | VACUUM CLEANING FILTER BAG - The disclosure relates to the field of vacuum cleaning and in particular the collection of air-entrained debris, in a filter bag. The filter bag is for use in vacuum cleaning apparatus, and comprises fine planar filtration means in the form of a collection bag and coarse planar filtration means both being adapted to be placed in a suction-induced air stream with the coarse filtration means disposed upstream of the fine filtration means, wherein the fine filtration means serves to provide a fine filter for retaining dust particles and wherein the coarse filtration means comprises a relatively coarse filter material having a thickness of at least 4 mm which provides a matrix volume in which dust may be collected. The volume occupied by the coarse filtration means comprises at least 2%, preferably at least 5%, most preferably at least 10% of the maximum internal volume defined by the collection bag. | 11-03-2011 |
| 20120111362 | FLOOR CLEANING MACHINE - A floor cleaning machine is described having a first drive head and a second drive head which are both pivotally mounted to a deck. The first and second drive heads are connected together with a link rod. The cleaning width of the cleaning machine can be changed by pivoting the first drive head about a pivot point on the deck. The pivoting movement of the first drive head causes a movement of the second drive head, via the link rod, in order to provide a new separation for the drive heads. | 05-10-2012 |
David Duncan, Lanarkshire GB
| Patent application number | Description | Published |
|---|---|---|
| 20090017998 | Exercise apparatus - An exercise apparatus comprising a housing which includes first and second gear members rotatably mounted within the housing. Wherein the first and second gear members each include a handle portion. The first and second gear members are connected to one another by a link member. The exercise apparatus also includes a friction control mechanism which controls a frictional force applied to the first and second gear members. | 01-15-2009 |
Ed Duncan, Strath GB
| Patent application number | Description | Published |
|---|---|---|
| 20080198240 | ERROR REDUCTION IN IMAGE SENSORS - A vignetting-type chromatic error, particularly found in image sensors having pixel dimensions of a few microns, may be corrected by applying to each color channel a gain factor which increases with the radial position of the pixel. The gain factor may be also controlled based upon ambient color temperature | 08-21-2008 |
Ed Duncan, Gairloch Highland GB
| Patent application number | Description | Published |
|---|---|---|
| 20080266406 | IMAGE SENSORS - A method of compensating for camera shake includes reading a sequential series of images from an image sensing array, establishing a sharpness value for each of the sequential series of images, and performing an image selection based upon each sharpness value. The sharpness value is calculated for each image of the sequential series thereof during the reading. | 10-30-2008 |
George Duncan, Norfolk GB
| Patent application number | Description | Published |
|---|---|---|
| 20090036464 | Treatment Of Posterior Capsule Opacification - This invention relates to a method of testing agents, such as sigma ligands for their potential use in treating posterior capsule opacification (PCO). The present invention also relates to the use of sigma ligands, such as sigma-1 antagonists in the manufacture of a medicament for preventing posterior capsule opacification (PCO), as well as methods of treating PCO using sigma ligands. | 02-05-2009 |
Iain Duncan, Southampton GB
| Patent application number | Description | Published |
|---|---|---|
| 20090319923 | METHOD FOR GENERATING ROLE-BASED USER INTERFACES UTILIZING UML MODELS - This disclosure proposes a set of rules for modeling that enable the generation of complete UI implementations at varying levels of abstraction. It also describes an engine that can interpret these rules and generate said UI. It differs from the prior art as it is not dependent on the raw data structure from the database but rather allows the concepts and objects a user interacts with to be modeled and mapped. It provides an additional level of sophistication allowing role-based customization and layout styles. | 12-24-2009 |
Iain Peter Duncan, Southampton GB
| Patent application number | Description | Published |
|---|---|---|
| 20100023922 | LINKING UML ACTIVITY DIAGRAM NODES TO UML CLASS DIAGRAM NODES BY USING PROPERTIES FROM APPLIED STEREOTYPES - The present disclosure is directed to a method for associating an UML activity diagram with an UML class diagram. The method may comprise applying stereotypes to nodes in the UML activity diagram; specifying properties for the stereotypes, the properties may include information for linking nodes in activity diagram to role names in the class diagram; providing a mapping between nodes in the activity diagram and relationship objects in the class diagram based on the properties; and associating the activity diagram with the class diagram utilizing the mapping. | 01-28-2010 |
Ian James Duncan, Hampshire GB
| Patent application number | Description | Published |
|---|---|---|
| 20090304510 | MARINE PROPULSION AND CONSTRUCTIONAL DETAILS THEREOF - A fin for use on a propeller, the fin comprising a lift generating section having a leading edge and a trailing edge, and a pair of surfaces extending between the leading and the trailing edges thereby defining a tip and a root having a root chord; and a dihedral section integrally formed with the root of the lift generating section and having a rotation axis about which, in use, the lift generating system can be rotated to vary the dihedral of the fin, the axis being generally parallel to the root chord of the lift generating section. | 12-10-2009 |
| 20100035489 | MARINE PROPULSION AND CONSTRUCTIONAL DETAILS THEREOF - A marine drive system mounted in the hull of a marine craft, the marine drive system comprising an engine connected to a gearbox by means of a drive shaft ( | 02-11-2010 |
| 20100048069 | MARINE PROPULSION AND CONSTRUCTIONAL DETAILS THEREOF - A propeller comprising a hub ( | 02-25-2010 |
| 20100075552 | MARINE PROPULSION AND CONSTRUCTIONAL DETAILS THEREOF - A propeller ( | 03-25-2010 |
| 20100150720 | MARINE PROPULSION AND CONSTRUCTIONAL DETAILS THEREOF | 06-17-2010 |
| 20100297896 | MARINE PROPULSION AND CONSTRUCTIONAL DETAILS THEREOF - A mount for supporting part of a marine drive system to a marine hull, the mount comprising a rigid outer housing ( | 11-25-2010 |
John Sidney Duncan, Bucks GB
| Patent application number | Description | Published |
|---|---|---|
| 20110137195 | Method and Apparatus for Monitoring Respiratory Activity - A method of monitoring respiratory activity includes obtaining a respiration sound signal. The respiration sound signal is processed to identify a frequency component corresponding to respiration, and an amplitude related parameter of the component is measured. If the measured parameter is in an indeterminate region then a temporal domain related parameter of the identified frequency component is measured. An apparatus for monitoring respiratory activity is also disclosed. | 06-09-2011 |
Jon Duncan, Middlesex GB
| Patent application number | Description | Published |
|---|---|---|
| 20110188237 | CONTAINER ILLUMINATION DEVICE - A self-contained illumination device ( | 08-04-2011 |
Kenneth Duncan, Cambusbarron GB
| Patent application number | Description | Published |
|---|---|---|
| 20080318954 | Compounds - The present invention relates to compounds of formula (I), or a pharmaceutically acceptable salts thereof, wherein: Z | 12-25-2008 |
| 20090318446 | 4-(1H-Indol-3-yl)-Pyrimidin-2-Ylamine Derivatives and Their Use in Therapy - The present invention relates to compounds of formula (I), or pharmaceutically acceptable salts thereof. The present invention seeks to provide further substituted heteroaryl-substituted pyrimidine derivatives. More specifically, the invention relates to compounds that have broad therapeutic applications in the treatment of a number of different diseases and/or that are capable of inhibiting one or more protein kinases. | 12-24-2009 |
Mcgregor Duncan, Suffolk GB
| Patent application number | Description | Published |
|---|---|---|
| 20110189164 | Peptide Stabilizer Compounds and Screening Method - Peptide stabilizer compounds are provided that in combination with a biologically active peptide, can increase the protease elimination half-time of the biologically active peptide in vivo. The peptide stabilizer compounds are preferably in the form of peptide sequences that confer resistance to proteolysis upon conjugated biologically active peptides. Also provided is a method for the selection of novel proteolysis resistant compounds from in vitro generated libraries, and pharmaceutical compositions comprising the stabilizer compounds identified thereby. | 08-04-2011 |
Neil Sutherland Duncan, Scotland GB
| Patent application number | Description | Published |
|---|---|---|
| 20100018693 | Pipeline entry system - An apparatus for inserting coiled tubing into a sub-sea pipeline comprising an adaptor which is releasably couplable to an anchor to hold the adaptor in position against lateral and/or vertical forces, the adaptor having: | 01-28-2010 |
Peter Reid Duncan, Aberdeen GB
| Patent application number | Description | Published |
|---|---|---|
| 20090036464 | Treatment Of Posterior Capsule Opacification - This invention relates to a method of testing agents, such as sigma ligands for their potential use in treating posterior capsule opacification (PCO). The present invention also relates to the use of sigma ligands, such as sigma-1 antagonists in the manufacture of a medicament for preventing posterior capsule opacification (PCO), as well as methods of treating PCO using sigma ligands. | 02-05-2009 |
Philip Duncan, Dundee GB
| Patent application number | Description | Published |
|---|---|---|
| 20120130810 | Advertising With Digital Media Content - A method is provided for dynamically adding customized advertisements with media content on digital media storage devices. A user may provide identification data to an automated machine or salesperson selling the media content at a retail location. Based upon the identification of the user, advertisements may be selected to be added to the media content. The selection of advertisements may be based upon previous transaction data, the genre of the media content, or characteristics identified for the user. Users may also select to change the quantity of advertisements to view based upon fees paid by the user for the media content. The user may pay additional fees to view less advertisements and the user may pay fewer fees and have more advertisements included with the media content. | 05-24-2012 |
Philip A. Duncan, Broughty Ferry GB
| Patent application number | Description | Published |
|---|---|---|
| 20090194580 | Terminal and device management method - A self-service terminal (SST), such as an ATM, comprises a processor, and two functionally similar devices, for example cash dispense units, and an input/output (IO) port. The processor receives status data from each of the similar devices and determines which set of status data to communicate to a remote host via the IO port dependent upon device status and health parameters contained within the status data. | 08-06-2009 |
Philip A. Duncan, Dundee GB
| Patent application number | Description | Published |
|---|---|---|
| 20090162184 | Reducing transaction time in a self-service terminal - Methods of reducing transaction time in a self-service terminal are described. The methods involve pre-stacking a defined amount of media, such as a commonly withdrawn amount of money, before the user has performed any service selection. During service selection, the user is given an option to withdraw the defined amount of money and if the user selects this option, the pre-stacked amount is dispensed. If the user selects an option to withdraw a different amount of money, a second dispenser in the self-service terminal may be used to stack and dispense this different amount. | 06-25-2009 |
Robert H. Duncan, Cleveland GB
| Patent application number | Description | Published |
|---|---|---|
| 20090288828 | Non-flammable, non-aqueous group IVB metal alkoxide crosslinkers and fracturing fluid compositions incorporating same - A non-aqueous, non-flammable Group IVB metal alkoxide crosslinker composition includes a non-aqueous, non-flammable Group IVB metal alkoxide, wherein the metal is chemically bonded to a glycol containing 4 or more carbons, to an alkoxy group containing 6 or more carbons, or a mixture of both. A fracturing fluid employed in the hydraulic fracturing of subterranean formations is formulated through mixture of the non-aqueous, non-flammable Group IVB metal alkoxide crosslinker composition with a polymer solution. | 11-26-2009 |
Robert Hume Duncan, Cleveland GB
| Patent application number | Description | Published |
|---|---|---|
| 20080275178 | Adhesion Promoting Compound - The invention comprises an adhesion promoter for a printing ink and a printing ink comprising the adhesion promoter. The adhesion promoter comprises the product of (a) mixing together a solution of a polymer or synthetic resin with an organophosphorus compound, and then (b) mixing the mixture formed in (a) with a titanium compound selected from a titanium halide, alkoxide, halo-alkoxide or a condensed titanium alkoxide or a mixture of more than one of these titanium compounds. | 11-06-2008 |
| 20100010144 | ADHESION PROMOTING COMPOUND - The invention comprises an adhesion promoter for a printing ink and a printing ink comprising the adhesion promoter. The adhesion promoter comprises the product of reacting together (a) a solution of a polymer or synthetic resin (b) a sulphonic acid or a derivative of a sulphonic acid, and (c) a metal compound selected from one or more of the group consisting of a metal halide, metal alkoxide, metal halo-alkoxide or a condensed metal alkoxide, wherein the metal is selected from titanium or zirconium. | 01-14-2010 |
Robert Hume Duncan, Stockton On Tees GB
| Patent application number | Description | Published |
|---|---|---|
| 20100292449 | WATER-STABLE COMPOUNDS, CATALYSTS AND CATALYSED REACTIONS - The invention provides a method of carrying out a Lewis-acid catalysed organic reaction in the presence of a Lewis acid catalyst comprising a metal-organic compound having the following formula: M(HO(CR | 11-18-2010 |
Roy Duncan, Aberdeen GB
| Patent application number | Description | Published |
|---|---|---|
| 20080262810 | NEURAL NET FOR USE IN DRILLING SIMULATION - A method of optimizing a drilling tool assembly including inputting well data into an optimization system, the optimization system having an experience data set and an artificial neural network. The method further including comparing the well data to the experience data set and developing an initial drilling tool assembly based on the comparing the well data to the experience data, wherein the drilling tool assembly is developed using the artificial neural network. Additionally, the method including simulating the initial drilling tool assembly in the optimization system and creating result data in the optimization system based on the simulating. | 10-23-2008 |
Stuart Duncan, Midlothian GB
| Patent application number | Description | Published |
|---|---|---|
| 20110079721 | APERTURE ARRANGEMENT - An aperture arrangement is disclosed, such as an aperture arrangement suitable for use with a dual wavelength infrared detector. A detector is disclosed which includes a casing; an aperture defined in one end of the casing; and a filter having an inner region and an outer region substantially (e.g., greater than 50%) covering the aperture; wherein the outer region of the filter transmits radiation within a first range of wavelengths and reflects radiation within a second range of wavelengths. | 04-07-2011 |