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Dumas, US
Carl B. Dumas, Tiverton, RI US
| Patent application number | Description | Published |
|---|---|---|
| 20100181332 | APPARATUS AND METHOD FOR DISTRIBUTING OPHTHALMIC LENSES - An apparatus for dispensing ophthalmic lens packages and methods of its use are described herein. | 07-22-2010 |
Catherine E. Dumas, Bothell, WA US
| Patent application number | Description | Published |
|---|---|---|
| 20110181600 | STRUCTURED ARRANGEMENT OF VISUAL ENDPOINTS - The present invention extends to methods, systems, and computer program products for structured arrangement of visual endpoints in diagrams. Generally, endpoint arrangements are consistently used on shapes in a domain (diagram type) based on common information flow characteristics of the domain. In addition, shape specific positioning of endpoints can be based on a shape's unique characteristics. Diagrams are more readable across an organization because diagrams have a more consistent flow structure in the form of endpoints and connections. Diagrams are also easier to construct because endpoints have predictable locations. | 07-28-2011 |
| 20110302555 | ASSIGNING TYPE PARAMETERS - The present invention extends to methods, systems, and computer program products for assigning type parameters. Embodiments of the invention permit using a visual editor to edit arbitrary object instances in a graphical fashion. Instances of generic types can be manipulated to change the type parameters for that generic (to be able to change a List | 12-08-2011 |
Catherine Elizabeth Dumas, Bothell, WA US
| Patent application number | Description | Published |
|---|---|---|
| 20110239164 | BREADCRUMB NAVIGATION THROUGH HEIRARCHICAL STRUCTURES - A viewer may be used to navigate through diagrammatic views of hierarchically structured documents. Expansion and collapse controls may be used to show or hide details regarding a particular node in the hierarchy. Furthermore breadcrumb navigation may be employed to show and hide details regarding the ancestral chain for a particular node in the hierarchy. | 09-29-2011 |
Craig Dumas, Mayer, MN US
| Patent application number | Description | Published |
|---|---|---|
| 20080272496 | PLANAR INTERCONNECT STRUCTURE FOR HYBRID CIRCUITS - Described herein is an electronic device in which one or more planar interconnect structure are interposed between two substrates each incorporating a hybrid circuit. The planar interconnect structure has a plurality of conductive traces formed on one of its faces for electrically connecting sets of interconnection points of each of the hybrid circuits. | 11-06-2008 |
| 20100009498 | PLANAR INTERCONNECT STRUCTURE FOR HYBRID CIRCUITS - Described herein is an electronic device in which one or more planar interconnect structure are interposed between two substrates each incorporating a hybrid circuit. The planar interconnect structure has a plurality of conductive traces formed on one of its faces for electrically connecting sets of interconnection points of each of the hybrid circuits. | 01-14-2010 |
| 20100158296 | HEARING ASSISTANCE DEVICE WITH STACKED DIE - The present subject matter relates to a hearing assistance device for an ear of a wearer comprising a microphone for receiving sound, hearing assistance electronics in communications with the microphone, the hearing assistance electronics including a hybrid circuit, and a wearable housing adapted to house at least the hearing assistance electronics. The hybrid circuit comprises a first integrated circuit die having one or more through-silicon-vias (TSVs), a first redistribution layer disposed on a surface of the first integrated circuit, and a second integrated circuit die having one or more contacts, the second integrated circuit die disposed on the first redistribution layer, wherein the first redistribution layer is adapted to connect one or more of the one or more TSVs of the first integrated circuit die to one or more of the one or more contacts of the second integrated circuit die. | 06-24-2010 |
David Scott Dumas, San Rafael, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20080272183 | Apparatus for repairing or reinforcing containers - Various solutions for repairing and reinforcing containers are disclosed. Embodiments of the present invention provide patches or reinforcing members which may be conveniently and effectively adhered to a container to improve the structural integrity thereof, protect the contents of the container, and provide an aesthetically-pleasing repair/reinforcement of the container. A substantially-planar patch may be used to repair or reinforce a surface of a container, while patches for adhering to multiple surfaces of the container may be used to repair or reinforce edges or corners. The thickness of the patch may be substantially less than that of its other dimensions to provide a low-profile repair or reinforcement, thereby reducing subsequent damage to the container caused by snagging or catching the patch on external objects. Additionally, the adhesive may bond the patch to the container to reduce separation and withstand loadings imparted to the container. | 11-06-2008 |
Donald J. Dumas, Wilmington, DE US
| Patent application number | Description | Published |
|---|---|---|
| 20100280251 | PROCESS FOR PREPARING 2-AMINO-5-CYANOBENZOIC ACID DERIVATIVES - Disclosed is a method for preparing a compound of Formula 1 comprising contacting a compound of Formula 2 with a metal cyanide reagent, a copper(I) salt reagent, an iodide salt reagent and at least one compound of Formula 3 | 11-04-2010 |
| 20110003998 | PROCESS FOR PREPARING 2-AMINO-5-CYANOBENZOIC ACID DERIVATIVES - Disclosed is a method for preparing a compound of Formula 1 comprising contacting a compound of Formula 2 with a metal cyanide reagent, a copper(I) salt reagent, an iodide salt reagent and at least one compound of Formula 3 | 01-06-2011 |
Elijah Dumas, San Jose, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090032130 | Fluid flow amplifier - A by-pass fluid flow amplifier which contains a primary nozzle and a primary profile for discharging compressed air into a conduit of the air amplifier and entraining ambient air in the process. A secondary nozzle and a secondary profile for discharging compressed air into the conduit of the air amplifier towards the rear that assists the primary nozzle such as to allow consistent fluid wall attachment of the compressed air and the entrained air caused by the primary nozzle and the primary profile. The secondary nozzle increases the total flow of the amplifier and prohibits the total flow from traveling towards the center of the conduit where flow reversal and turbulence are likely to occur. | 02-05-2009 |
Elisha Dumas, San Jose, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090032130 | Fluid flow amplifier - A by-pass fluid flow amplifier which contains a primary nozzle and a primary profile for discharging compressed air into a conduit of the air amplifier and entraining ambient air in the process. A secondary nozzle and a secondary profile for discharging compressed air into the conduit of the air amplifier towards the rear that assists the primary nozzle such as to allow consistent fluid wall attachment of the compressed air and the entrained air caused by the primary nozzle and the primary profile. The secondary nozzle increases the total flow of the amplifier and prohibits the total flow from traveling towards the center of the conduit where flow reversal and turbulence are likely to occur. | 02-05-2009 |
Ellen M. Dumas, Marietta, GA US
| Patent application number | Description | Published |
|---|---|---|
| 20100090543 | PORTABLE TRANSFORMER AND METHOD FOR IMPROVING RELIABILITY OF ELECTRIC POWER DELIVERY - The present invention relates to an apparatus and method for improving the transportation and installation of portable step-up power transformers for a power generating station due to failure or unavailability of installed step up transformers. A large MVA portable transformer may be used to alleviate or minimize these issues by being purpose built for transportability and commissioning speed. The portable transformer is transportable by road or lighter rail. Its size and weight are arranged to overcome restrictions such was weight limits, bridge constraints, and power line constraints. This device may also provide for rapid commissioning and decommissioning. This transformer may be a set of three single-phase units of sufficient size to be used as a generator step up transformer in three-phase operation. | 04-15-2010 |
| 20110298287 | PORTABLE TRANSFORMER AND METHOD FOR IMPROVING RELIABILITY OF ELECTRIC POWER DELIVERY - The present invention relates to an apparatus and method for improving the transportation and installation of portable step-up power transformers for a power generating station due to failure or unavailability of installed step up transformers. A large MVA portable transformer may be used to alleviate or minimize these issues by being purpose built for transportability and commissioning speed. The portable transformer is transportable by road or lighter rail. Its size and weight are arranged to overcome restrictions such was weight limits, bridge constraints, and power line constraints. This device may also provide for rapid commissioning and decommissioning. This transformer may be a set of three single-phase units of sufficient size to be used as a generator step up transformer in three-phase operation. | 12-08-2011 |
Gregory J. Dumas, Glendale, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20100126749 | Enclosure assembly - An enclosure assembly that includes a molded electrical outlet box that is configured to house there within a conventional duplex outlet and a conventional prior art AC transformer that is plugged into the duplex outlet. The assembly also includes a novel cover having an opening through which the wire cable of the transformer extends. An expandable grommet which sealably engages the wire cable is mounted within the opening on the cover. | 05-27-2010 |
Howard Dumas, San Jose, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090032130 | Fluid flow amplifier - A by-pass fluid flow amplifier which contains a primary nozzle and a primary profile for discharging compressed air into a conduit of the air amplifier and entraining ambient air in the process. A secondary nozzle and a secondary profile for discharging compressed air into the conduit of the air amplifier towards the rear that assists the primary nozzle such as to allow consistent fluid wall attachment of the compressed air and the entrained air caused by the primary nozzle and the primary profile. The secondary nozzle increases the total flow of the amplifier and prohibits the total flow from traveling towards the center of the conduit where flow reversal and turbulence are likely to occur. | 02-05-2009 |
Jacques Dumas, Orange, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20080269265 | Inhibition Of Raf Kinase Using Symmetrical And Unsymmetrical Substituted Diphenyl Ureas - This invention relates to the use of a group of aryl ureas in treating raf mediated diseases, and pharmaceutical compositions for use in such therapy. | 10-30-2008 |
| 20080300281 | Inhibition of p38 Kinase Activity Using Aryl and Heteroaryl Substituted Heterocyclic Ureas - This invention relates to the use of a group of aryl ureas in treating cytokine mediated diseases other than cancer and proteolytic enzyme mediated diseases other than cancer, and pharmaceutical compositions for use in such therapy. | 12-04-2008 |
| 20090093526 | INHIBITION OF P38 KINASE USING SYMMETRICAL AND UNSYMMETRICAL DIPHENYL UREAS - This invention relates to the use of a group of aryl ureas in treating cytokine mediated diseases and proteolytic enzyme mediated diseases, and pharmaceutical compositions for use in such therapy. | 04-09-2009 |
| 20090118268 | OMEGA-CARBOXY ARYL SUBSTITUTED DIPHENYL UREAS AS p38 KINASE INHIBITORS - This invention relates to the use of a group of aryl ureas in treating p38 mediated diseases, and pharmaceutical compositions for use in such therapy. | 05-07-2009 |
| 20120040986 | OMEGA CARBOXYARYL SUBSTITUTED DIPHENYL UREAS AS RAF KINASE INHIBITORS - This invention relates to the use of a group of aryl ureas in treating raf mediated diseases, and pharmaceutical compositions for use in such therapy. | 02-16-2012 |
| 20120046290 | INHIBITION OF P38 KINASE ACTIVITY USING SUBSTITUTED HETEROCYCLIC UREAS - This invention relates to the use of a group of aryl ureas in treating cytokine mediated diseases, other than cancer and proteolytic enzyme mediated diseases, other than cancer, and pharmaceutical compositions for use in such therapy. | 02-23-2012 |
Jacques Dumas, Waltham, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20080214545 | Substituted Pyrazolyl Urea Derivatives Useful in the Treatment of Cancer - The present invention relates to compounds of formula (I), pharmaceutical compositions which contain them and methods for treating cancer using compounds of formula (I). | 09-04-2008 |
| 20100261719 | CHEMICAL COMPOUNDS - In one aspect, the present invention relates to compounds of Formula (I) and to pharmaceutically acceptable salts thereof, wherein: n is 1 to 4; and R | 10-14-2010 |
| 20110136809 | Substituted Pyrazolyl Urea Derivatives Useful In The Treatment Of Cancer - The present invention relates to compounds of formula (I), pharmaceutical compositions which contain them and methods for treating cancer using compounds of formula (I). | 06-09-2011 |
| 20110178064 | SPIRO CONDENSED BARBITURIC ACID DERIVATIVES FOR USE AS ANTIBACTERIAL - In one aspect, the present invention relates to compounds of Formula (I): to pharmaceutically acceptable salts thereof, to methods of using them to treat bacterial infections, and to method for their preparation. | 07-21-2011 |
Jacques Dumas, Carlisle, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100081812 | SUBSTITUTED PYRIMIDINE DERIVATIVES USEFUL IN THE TREATMENT OF CANCER AND OTHER DISORDERS - Substituted pyrimidine derivatives of formula (I), salts, metabolites, prodrugs and diastereoisomeric forms (both isolated stereoisomers and mixtures of stereoisomers) thereof (wherein A=pyrimidine) pharmaceutical compositions containing such compounds and the use of those compounds or compositions for treating hyper-proliferative and angiogenesis disorders, as a sole agent or in combination with other active ingredients, e.g., cytotoxic therapies. | 04-01-2010 |
| 20110294776 | Pyrrolo[2,1-F] [1,2,4] Triazin-4-Ylamines IGF-1R Kinase Inhibitors for the Treatment of Cancer and Other Hyperproliferative Diseases - This invention relates to novel compounds of formula (I). Formula (I) in which the variable groups are as defined in the specification and claims, to pharmaceutical compositions containing them, and to a method of treatment using them for treatment of cancer. | 12-01-2011 |
Jacques P. Dumas, Waltham, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090082328 | Substituted phenylamino-benzene derivatives useful for treating hyper-proliferative disorders and diseases associated with mitogen extracellular kinase activity - This invention relates to novel substituted phenylamino-benzene compounds, pharmaceutical compositions containing such compounds and the use of those compounds or compositions for treating hyper-proliferative and/or angiogenesis disorders, as a sole agent or in combination with other active ingredients. | 03-26-2009 |
| 20110263597 | SUBSTITUTED PYRIDINES AND PYRIDAZINES WITH ANGIOGENESIS INHIBITING ACTIVITY - Methods of treating a mammal having a condition characterized by abnormal angiogenesis or hyperpermiability processes using substituted pyridazines having angiogenesis inhibiting activity and the generalized structural formula | 10-27-2011 |
James T. Dumas, Clinton Township, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20080308072 | HYDROCARBON SEPARATION FROM AIR USING MEMBRANE SEPARATORS IN RECIRCULATION TUBE - A tubular separation system for separating a mixture of hydrocarbons and air at a fuel tank in an automotive vehicle, comprises; a fuel tank containing hydrocarbon fuel and a mixture of hydrocarbon fuel vapor and air; a fuel filler pipe connected to the fuel tank for conveying hydrocarbon fuel from a source of hydrocarbon fuel into the fuel tank; a separation module comprising a membrane for separating the hydrocarbon vapor from air; a first tubular member between the fuel tank and the separation module for conveying the mixture of air and hydrocarbon fuel vapor from the fuel tank to the separation module; a second tubular member between the separation module and the fuel tank for conveying hydrocarbon fuel vapor, separated from the mixture of air and hydrocarbon fuel vapor, from the separation module to the fuel tank; and a third tubular member between the separation module and the fuel filler pipe for conveying air, separated from the mixture of air and hydrocarbon fuel vapor, from the separation module to the fuel filler pipe. A device that provides a pressure differential across said membrane is employed to facilitate the separation of air and hydrocarbon from the air/hydrocarbon mixture. The air containing any residual fuel vapor is directed to an emissions canister where the residual fuel vapor is adsorbed and eventually consumed by the internal combustion engine while the air is released to the atmosphere. | 12-18-2008 |
| 20080308073 | EVAPORATIVE EMISSIONS CANISTER HAVING AN INTEGRAL MEMBRANE - An evaporative emissions canister for use in an automotive evaporative emission system to control emission of fuel vapors to the atmosphere. The canister includes an integrally molded housing having a circumferential side member, a top member and a bottom member; a hydrocarbon-adsorbing material disposed therein so as to provide a vapor adsorbent chamber for adsorbing hydrocarbon fuel vapor flowing therethrough; and an internal membrane located above the vapor adsorbent chamber in the fresh air side of the adsorbent chamber for preventing the fuel vapor molecules from passing through the internal membrane while allowing the air molecules to pass therethrough. The internal membrane is characterized as a cellular fibular material having physical properties sufficient to effectively cause any fuel vapor component molecules and associated pollutants to be sufficiently filtered or separated on the membrane while allowing fresh air molecules to pass freely therethrough. | 12-18-2008 |
| 20080308074 | EVAPORATIVE EMISSIONS CANISTER WITH EXTERNAL MEMBRANE - An evaporative emissions system is used in an automotive evaporative emission system including a fuel tank coupled to an automotive engine to control emission of fuel vapors to the atmosphere. The system includes (1) an evaporative emissions canister comprising a unitary molded housing having a circumferential side member, a top member and a bottom member; a hydrocarbon-adsorbing material disposed therein so as to provide a vapor adsorbent chamber for adsorbing hydrocarbon fuel vapor flowing therethrough; and (2) a second housing containing a membrane, the second housing located adjacent the fresh air line of the evaporative emissions canister for preventing fuel vapor molecules and pollutants associated therewith, from passing through the membrane while allowing the air molecules to pass therethrough. A method is provided for preventing or substantially reducing hydrocarbon emissions to the atmosphere. | 12-18-2008 |
| 20080308075 | AUTOMOTIVE FUEL SYSTEM FOR SUBSTANTIALLY REDUCING HYDROCARBON EMISSIONS INTO THE ATMOSPHERE, AND METHOD - An evaporative emissions system is used in an automotive evaporative emission system including a fuel tank coupled to an automotive engine to control emission of fuel vapors to the atmosphere. The system includes an evaporative emissions canister comprising a first molded housing having a circumferential side member, a top member and a bottom member; a hydrocarbon-adsorbing material disposed therein so as to provide a vapor adsorbent chamber for adsorbing hydrocarbon fuel vapor flowing therethrough; and an auxiliary housing containing a carbon-coated reticulated material, the reticulated housing located in the fresh air line of the evaporative emissions canister for preventing fuel vapor molecules from passing through the carbon-coated reticulated material while allowing the air molecules to pass therethrough. A method is provided for preventing or reducing hydrocarbon emissions to the atmosphere. | 12-18-2008 |
Jaques Dumas, Carlisle, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110071125 | SUBSTITUTED PHENYLAMINO-BENZENE DERIVATIVES USEFUL FOR TREATING HYPER-PROLIFERATIVE DISORDERS AND DISEASES ASSOCIATED WITH MITOGEN EXTRACELLULAR KINASE ACTIVITY - This invention relates to novel substituted phenylamino-benzene compounds, pharmaceutical compositions containing such compounds and the use of those compounds or compositions for treating hyper-proliferative and/or angiogenesis disorders, as a sole agent or in combination with other active ingredients. | 03-24-2011 |
Jerald Dumas, Nashville, TN US
| Patent application number | Description | Published |
|---|---|---|
| 20100247672 | POLYURETHANE/BONE COMPOSITIONS AND METHODS - A flowable, injectable composite that comprises mineralized allograft bone; and at least one degradable polyurethane that has a quasi-prepolymer and a resin mix, the resin mix having a polyester polyol and a catalyst; wherein the composite has a compression strength of greater than about 10 MPa and a modulus of greater than about 1 GPa. | 09-30-2010 |
Jerald E. Dumas, Nashville, TN US
| Patent application number | Description | Published |
|---|---|---|
| 20100112032 | Bone/Polyurethane Composites and Methods Thereof - Present inventions present composites of bone particles and polyurethane(s), as well as methods of making such composite and uses thereof. A porous composite comprises a plurality of bone particles; and polyurethanes with which the bone particles are combined. To prepare a porous composite, a composition comprise a plurality of bone particles, polyurethane precursors including polyisocyanate prepolymers and polyols, water and catalyst. A composition is either naturally moldable and/or injectable, or it can be made moldable and/or injectable. After implantation or injection, a composition may be set to form a porous composite that provides mechanical strength and supports the in-growth of cells. Inventive composites have the advantage of being able to fill irregularly shape implantation site while at the same time being settable to provide the mechanical strength for most orthopedic applications. | 05-06-2010 |
| 20100297082 | WEIGHT-BEARING POLYURETHANE COMPOSITES AND METHODS THEREOF - Present inventions present composites of particles and polymers, as well as methods of making such composite and uses thereof. A low or non-porous composite comprises a plurality of bone particles; and polyurethane components with which the bone particles are combined. Provided composites can be prepared in a one-shot process. Alternatively or additionally, composites can be prepared by compression molding under a high pressure. Before or after implantation, provided composites may be set to form a hardened state of composites that provides mechanical strength and supports the in-growth of cells. | 11-25-2010 |
Jerald E. Dumas, Atlanta, GA US
| Patent application number | Description | Published |
|---|---|---|
| 20110237704 | Particle/Polyurethane Composites and Methods thereof - The present invention encompasses the finding that certain treatments (e.g., surface modifications) to particulate materials can provide surprising and unexpected benefits and/or features to composites and/or compositions as described herein. In some embodiments, such benefits and/or features may render particular composites and/or compositions particularly useful in a certain therapeutic context (e.g, for repair of tibial plateau, femoral head, craniofacial, or lateral mandibular body defects). The present invention demonstrates that certain composites and/or compositions wherein the particular material is or comprises defatted bone have surprising and beneficial attributes. | 09-29-2011 |
Jim Dumas, Leslie, GA US
| Patent application number | Description | Published |
|---|---|---|
| 20090141507 | LIGHTING FIXTURE CHANNEL WITH DIFFUSER - Embodiments of this invention may include a lighting fixture having a channel provided with an integrally-formed structure for retaining a diffuser. According to one embodiment of the present invention, the end caps of a channel may include integrally formed retaining arms intended to abut and retain a diffuser located within the channel of the light fixture. Other embodiments of the invention provide interlocking structure for retaining the channel end caps in the desired position relative to the channel. According to one embodiment of the present invention, the end caps are secured to the channel body through a tab-slot connection. The slot and tab combination secure the end caps in a desired angle relative to the channel body. | 06-04-2009 |
John Joseph Dumas, Bloomfield Hills, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20110311935 | Orthodontic connector assembly and a method for treating teeth - An orthodontic connector assembly | 12-22-2011 |
John Medford Dumas, Madison, MS US
| Patent application number | Description | Published |
|---|---|---|
| 20090249978 | PROCESS FOR PRODUCING AN IMPROVED ASPHALT USING POLYPHOSPHORIC ACID WITH AIR BLOWING - A process is provided for producing an improved asphalt composition is air blown for a reduced period of time prior to addition of polyphosphoric acid. The air blowing process is performed at temperatures and using air volumes typically used for air blown asphalt. The process may be performed using neat asphalt, or it may be used on mixtures of asphalt with flux, slop, or mixtures of flux and slop. After the initial air blowing period, polyphosphoric acid is added to the asphalt. The polyphosphoric acid may be added while the asphalt is at temperature, or the asphalt may be allowed to cool slightly before the addition of the polyphosphoric acid. Following addition of the polyphosphoric acid, the asphalt may undergo further air blowing to obtain desired properties. | 10-08-2009 |
Karen Dumas, Holland, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20090044729 | MULTI-FUNCTIONAL RUNNING BOARD AND RAMP APPARATUS - A running board system is provided for the light truck market, where a beam of the running board is removable to double as a ramp. For example, a single one of these beams can be used to guide a motorcycle onto a truck bed, or alternatively a pair of these removable beams can be used to provide a ramp for guiding a two wheel cart (e.g., hand truck), four wheel vehicle, or snowmobile onto the truck bed. Optionally, the beam includes lockable storage and/or includes brackets for securement of the beam(s) to the truck's tailgate when used as a ramp. | 02-19-2009 |
Kathleen Dumas, Cupertino, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090203722 | Novel compositions and methods for enhancing potency or reducing adverse side effects of opiold agonists - The invention generally relates to novel compositions and methods with an opioid agonist and an opioid antagonist to differentially dose a human subject so as to either enhance analgesic potency without attenuating an adverse side effect of the agonist, or alternatively maintain the analgesic potency of the agonist while attenuating an adverse side effect of the agonist. The invention additionally relates to novel opioid compositions and methods for the gender-based dosing of men and women. | 08-13-2009 |
Michael L. Dumas, Richmond, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090258826 | Pituitary adenylate cyclase activating peptide (PACAP) receptor (VPAC2) agonists and their pharmacological methods of use - This invention provides novel peptides that function in vivo as agonists of the VPAC2 receptor. These insulin secretagogue polypeptides are shown to lower blood glucose in vivo more than controls upon glucose challenge. The polypeptides of this invention are also stable in formulation and have long half-lives. The peptides of the present invention provide a new therapy for patients with decreased endogenous insulin secretion, in particular type 2 diabetics. In particular, the invention is a polypeptide selected from a specific group of VPAC2-related polypeptides, or functional equivalents thereof. The invention is also directed to a method of treating a metabolic disease in a mammal comprising administering a therapeutically effective amount of the insulin secretagogue peptides to said mammal. Also disclosed are methods of making the peptides, both recombinant and synthetic. | 10-15-2009 |
Oliver J. Dumas, East Sandwich, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110016891 | Cryopump Network - A vacuum network control system includes a plurality of nodes configured for control over operational processes of the system. The plural nodes are configured, in a network ring or other topology, as a selectable master node for controlling the operational processes. Control can be distributed among, and passed between, each of the nodes. Each node on the network monitors adjacent network connectors to detect a fault in the network. In response to a detected fault, a disconnect is mapped to the fault, and the network topology is reconfigured for continued communication among the nodes and with external devices. | 01-27-2011 |
Philip Dumas, Morrisville, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090062112 | Boron carbide as an effective Friedel-Crafts type catalyst - The compound boron carbide, B | 03-05-2009 |
Phillip James Dumas, Deland, FL US
| Patent application number | Description | Published |
|---|---|---|
| 20090238096 | APPARATUS AND METHOD FOR DYNAMICALLY UPDATING AND COMMUNICATING WITHIN FLEXIBLE NETWORKS - A software-based application dynamically updates user lists and enables communication between various network communication devices within a wireless network. The software-based application automatically builds and maintains a list of available users associated with the network communication devices in real-time, without reliance on a centralized server for authentication. Various types of communication, between network communication devices of the wireless network including text-based messaging, audio and video communication and file transfer are performed. | 09-24-2009 |
| 20090274089 | SYSTEM AND METHOD FOR ESTABLISHING AND MAINTAINING COMMUNICATIONS ACROSS DISPARATE NETWORKS - A system for establishing and maintaining communications across disparate networks comprises a satellite dish and control unit comprising a network management server and a satellite data conversion component. The control unit may further comprise an application server and a satellite dish alignment component. The system may further comprise at least one access point and a plurality of wireless routers. In certain embodiments, the system is relatively easy to deploy and can even be used when traditional network infrastructure is unavailable. | 11-05-2009 |
Reginald Dumas, Conyers, GA US
| Patent application number | Description | Published |
|---|---|---|
| 20110277330 | PLUMB POST APPARATUS HAVING BIPOD LEGS AND METHOD OF USE THEREOF - A plumb post apparatus for retaining a mason's line for laying a brick course, the apparatus comprising two vertical posts each having two legs of adjustable length that pivot outward to form stabilizers. The legs are secured to adjacent sides of the posts, thus extending at right angles to each other. The posts can be secured via spikes through base plates at the bottoms of the posts and the legs are secured in place via stakes that are pivotally secured to the ends of the legs and which can be driven into a ground surface. Levels on adjacent sides of the posts indicate when the apparatus is in level disposition. | 11-17-2011 |
Richard H. Dumas, East Haven, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20110123587 | Antimicrobial protection for plastic structures - Disclosed is a composition and method for providing antimicrobial protection to plastic structures, such as plastic decking, planking, fencing, and panels. The method comprises applying a water-soluble biocide to the metal-containing structure, and converting the soluble biocide to a water-insoluble metal biocide salt that is adsorbed on the surface of, or into the porous structure of the plastic material. The slow release of the insoluble antimicrobial agent from the surface or from within the pores of said plastic structure provides antimicrobial protection for the plastic structure. | 05-26-2011 |
Russell H. Dumas, Germantown, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20110148794 | Haptic Interface for Palpation Simulation - A method for interfacing a user with a computer running an application program, the computer generating a graphical environment comprising a graphical object and a graphical representation of at least a portion of a living body, comprises providing an object in communication with the computer, controlling the graphical object in relation to manipulation of at least a portion of the object by the user, and outputting a haptic sensation to the user when the graphical object interacts with a region within the graphical representation to provide the user with haptic feedback related to a simulated palpation of the region. | 06-23-2011 |
Stephane Dumas, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20120114557 | Methods for Collagen Imaging - Diagnostic compositions and methods for imaging and/or assessing collagen are described. The diagnostic compositions can include collagen binding peptides. | 05-10-2012 |
Stephane A. Dumas, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110152235 | Aminopyrimidine Kinase Inhibitors - Disclosed are compounds, pharmaceutical compositions containing those compounds, and uses of the compounds and compositions as modulators of casein kinase 1 (e.g., CK1γ), casein kinase 2 (CK2), Pim 1, Pim2, Pim3, the TGFβ pathway, the Wnt pathway, the JAK/STAT pathway, and/or the mTOR pathway. Uses are also disclosed for the treatment or prevention of a range of therapeutic indications due at least in part to aberrant physiological activity of casein kinase 1 (e.g., CK1γ), casein kinase 2 (CK2), Pim 1, Pim2, Pim3, the TGFβ pathway, the Wnt pathway, the JAK/STAT pathway, and/or the mTOR pathway. | 06-23-2011 |