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Duggan, GB

Alex Duggan, Epsom GB

Patent application numberDescriptionPublished
20110151010ANTI-SNORING TREATMENT COMPRISING POSITIVELY CHARGED MULTILAMELLAR MICROPARTICLES - A composition for nasal or buccal application comprising a distribution of multilayer microparticles in an inactive base, at least one ingredient having activity on the mucosa of the nose/throat, being adsorbed within the layers of the microparticles so as to be progressively released over time in use.06-23-2011

Heather Mary Ellen Duggan, Horsham GB

Patent application numberDescriptionPublished
20110124638Pyrido-, Pyrazo- and Pyrimido-Pyrimidine Derivatives as mTOR Inhibitors - There is provided a compound of formula I:05-26-2011

Heather Mary Ellen Duggan, Cambridge GB

Patent application numberDescriptionPublished
20090042865DNA-PK INHIBITORS - A compound of formula I:02-12-2009
20110130386DNA-PK INHIBITORS - A compound of formula (I) wherein: R1 and R2 are independently selected from hydrogen, an optionally substituted C06-02-2011

James Duggan, London GB

Patent application numberDescriptionPublished
20120115771CARRIER - A pharmaceutical composition is provided comprising a vitamin E derivative, an anionic phopholipid-binding protein, an anionic phospholipid and a sterol. Also provided is a method for preparing a composition for delivering a cargo to a subject comprising a) forming liposomes from a vitamin E derivative, an anionic phospholipid-binding protein such as annexin, an anionic phospholipid such as phosphatidylserine and a sterol; and b) encapsulating the cargo in the liposomal composition.05-10-2012

Matthew Duggan, Surrey GB

Patent application numberDescriptionPublished
20110161741TOPOLOGY BASED CORRELATION OF THRESHOLD CROSSING ALARMS - Method, apparatus and computer program product for correlating performance events in a data processing system. A first event is received at one of a first device and a second device of the data processing system, and a second event is received at one of the first device and the second device. A type of a connection between the first device and the second device is identified to form an identified type of connection, and a relationship between the first event and the second event is determined based on the identified type of connection between the first device and the second device.06-30-2011

Matthew E. Duggan, Chertsey GB

Patent application numberDescriptionPublished
20080304496Inferred Discovery Of A Data Communications Device - Methods, apparatus, and products for inferred discovery of a data communications device connected to a router, unreachable by a management module, and characterized by a device address are disclosed that include querying, by the management module, the router for connection data and identifying, by the management module in dependence upon the connection data, the device address.12-11-2008
20100332645METHOD AND SYSTEM FOR RESOURCE MANAGEMENT IN A COMPUTING ENVIRONMENT - A method and system for monitoring resources in a network of resources in a computing environment, is provided. One implementation involves discovering resources in the network; constructing a topology model including event information for each discovered resource; providing queries for polling the models for event information, such that the resources need not be polled; executing one or more queries against one or more models; evaluating the query results to ascertain whether or not an event has affected what is considered to be normal for the result of each query; and presenting the evaluation results to enable monitoring of the resources.12-30-2010
20110032260ENHANCING VISUALIZATION OF RELATIONSHIPS AND TEMPORAL PROXIMITY BETWEEN EVENTS - Components and functionality can be implemented in an event management application to display events along a timeline. A display interval can be configured for the timeline and a scroll bar can allow scrolling to view different time periods on the timeline. In addition, filters may be applied to the events, so that relationships between events may be visualized. For example, the events may be filtered by network resource name, so that groups of events related to each network resource can be grouped together along the timeline.02-10-2011
20110035628System And Method For Correlating Carrier Ethernet Connectivity Fault Management Events - A method, system and computer-usable medium are disclosed for suppressing managed endpoint (MEP) child events in a network. A MEP multicast message is broadcast by an originating MEP. Responses received from peer MEPs within a selected time interval are processed to determine their respective IP address, MAC address, and VLAN. If this information is not currently stored in a table of peer MEP device information associated with the originating MEP, then it is added. The responding MEP is then marked in the peer MEP device table as having responded. Peer MEP devices that have responded to previous multicast messages, but have now failed to respond within the selected time interval, are determined. A MEP network event is generated, comprising the IP address of the device containing the MEP, the MAC address for inward-facing MEPs, the MAC address of the associated bridge, the port addresses for outward-facing MEPs, and associated VLAN information. If another MEP network event occurs, the MAC address of the MEP and its VLAN information is determined. If the VLAN associated with the current MEP network event contains a MAC address associated with a prior MEP network event, then the MEP network event is designated as a child MEP network event and suppressed. Otherwise, the MEP network event is designated as a parent MEP network.02-10-2011
20110292834Maintaining Time Series Models for Information Technology System Parameters - A network-centric modeling mechanism is provided for updating network models in order to mitigate network issues. The network-centric modeling mechanism determines for each component in a plurality of components whether a system parameter in a set of parameters particular to the component has deviated from a predicted system parameter value in a set of predicted system parameter values past a predetermined threshold. Responsive to the system parameter deviating from the predicted system parameter value past the predetermined threshold, the network-centric modeling mechanism generates an event stream indicating a sufficient deviation. The network-centric modeling mechanism determines whether the event stream matches a previous pattern. Responsive to identifying the previous pattern that matches the event stream, the network-centric modeling mechanism preemptively mitigates any related issues in the component or in a related component in the plurality of components using topology-aware indices associated with the previous pattern.12-01-2011

Patent applications by Matthew E. Duggan, Chertsey GB

Matthew E. Duggan, Surrey GB

Patent application numberDescriptionPublished
20100306360NETWORK MANAGEMENT DISCOVERY TOOL - A method, apparatus, and computer program product for discovering network paths between network devices in a distance-vector network are provided. The method may include providing a node model of network devices in a distance-vector network. The node model may include a network address corresponding to a network device. The network address may be used to query the network device for routing information. This routing information may be used to identify another network address corresponding to a second network device, and to identify a path from the first network device to the second network device. These devices and the path therebetween may be mapped in the node model. Finally, the second network device may be queried for subsequent routing information to identify and map subsequent devices and paths.12-02-2010

Matthew Edward Duggan, Surrey GB

Patent application numberDescriptionPublished
20090210523NETWORK MANAGEMENT METHOD AND SYSTEM - A network management method and system. The method includes identifying and accessing a network device. A set of software loopback interfaces configured for the network device is retrieved. A first set of Internet protocol (IP) addresses associated the set of software loopback interfaces is retrieved. A second set of IP addresses associated with the first set of IP addresses is retrieved. A set of next-hop interfaces is retrieved. A network management topology model based on the network device, the set of software loopback interfaces, the first set of IP addresses, the second set of IP addresses, and the set of next-hop interfaces is generated. The network management topology model indicates that each IP address of the second set of IP addresses that is adjacent to an IP address of the first set of IP addresses is reachable via an associated next-hop interface of the set of next-hop interfaces.08-20-2009

Matthew Edward Duggan, Chertsey GB

Patent application numberDescriptionPublished
20090132862METHOD AND APPARATUS FOR NETWORK FAULT ISOLATION - A computer implemented method, apparatus, and computer usable program code for network fault isolation. A plurality of real-time path traces is performed between the sender and the receiver to form a plurality of trace paths in response to receiving a request for the network fault isolation between a sender and a receiver. A determination is made as to whether an asymmetry is present between the sender and the receiver from the plurality of trace paths. A set of routers is identified with each trace path in the plurality of trace paths to form a plurality of identified routers. Each event stored is identified for the plurality of identified routers to form a set of identified events.05-21-2009
20090313362SYSTEM AND METHOD FOR BUILDING NETWORK MODEL IN NETWORK MANAGEMENT APPLICATION - A system and associated method for building a network model of a network for a network management application. The network management application discovering a router discovers peering routers using network reachability information in a routing protocol. Undiscoverable peering routers are created within the network model by the network management application from network reachability information. Also a local subnet for the router, a remote subnet for a peer, a remote interface between the router and the peer also may be created to model the network in a network management application from information from the routing protocol.12-17-2009

Michael John Duggan, London GB

Patent application numberDescriptionPublished
20080319167Clostridial toxin derivatives able to modify peripheral sensory afferent functions - This invention describes a novel agent for the targeted control of a mammalian cell activity, in particular the agent is used to control the interaction of particular cell types with their external environment. The agent has applications as a pharmaceutical for the treatment of a variety of disorders. An agent according to the invention comprises three Domains B, T and E linked together in the following manner: Domain B-Domain T-Domain E where Domain B is the Binding Domain which binds the agent to a Binding Site on the cell which undergoes endocytosis to produce an endosome, Domain T is the Translocation Domain which translocates the agent (with or without the Binding Site) from within the endosome across the endosomal membrane into the cytosol of the cell, Domain E is the Effector Domain which inhibits the ability of the Recyclable Membrane Vesicles to transport the Integral Membrane Proteins to the surface of the cell.12-25-2008
20090131645Clostridial toxin derivatives able to modify peripheral sensory afferent functions - This invention describes a novel agent for the targeted control of a mammalian cell activity, in particular the agent is used to control the interaction of particular cell types with their external environment. The agent has applications as a pharmaceutical for the treatment of a variety of disorders. An agent according to the invention comprises three Domains B, T and E linked together in the following manner: Domain B-Domain T-Domain E where Domain B is the Binding Domain which binds the agent to a Binding Site on the cell which undergoes endocytosis to produce an endosome, Domain T is the Translocation Domain which translocates the agent (with or without the Binding Site) from within the endosome across the endosomal membrane into the cytosol of the cell, Domain E is the Effector Domain which inhibits the ability of the Recyclable Membrane Vesicles to transport the Integral Membrane Proteins to the surface of the cell.05-21-2009

Patent applications by Michael John Duggan, London GB

Paul Duggan, London GB

Patent application numberDescriptionPublished
20100153290Methods of matching job profiles and candidate profiles - Methods and computer program products are described for matching candidate profiles and job profiles during a job search or a people search. Methods of matching of a candidate profile with a plurality of job profiles, or a job profile with a plurality of candidate profiles are disclosed. During the disclosed methods a strict initial match between a candidate profile and a plurality of job profiles, or between a job profile and a candidate profile is initially undertaken in order to select matched profiles. Thereafter a fuzzy match between the candidate profile and the matched job profiles, or between a job profile and the matched candidate profile based on the degree of similarity between the respective profiles is used to determine the relevance of the matched profiles. A job or candidate profile and/or a matched job or candidate profile may be forwarded using a social network. The profiles preferably include psychometric information or criteria.06-17-2010

Paul Edward Duggan, Cambridge GB

Patent application numberDescriptionPublished
20090056150Blade03-05-2009
20090133890Power Tool Attachments - An attachment is for a power tool having a chuck. The attachment has a connection portion in the form of a shaft for connecting the attachment with the tool, during use, by attachment in the chuck. The attachment further has a blade portion which, in use, is offered to a surface indicated at, and to which hammer blows are transmitted from the hammer tool, thereby causing the blade portion to cut into the surface.05-28-2009
20090304468Drill Bit - A drill bit has a cutting face for engaging a workpiece. The cutting face forms an annular cut. A mouth is bounded by the cutting face and receives material of the workpiece from within the annular cut, as cutting progresses. An internal passage has a mouth through which this material can leave the bit.12-10-2009
20100031947Blade - A blade comprises a strip having a main body portion and an edge portion. Cutting medium in the form of a diamond grit is secured to the strip by braze material. The edge portion is thinner than the main body portion.02-11-2010

Patent applications by Paul Edward Duggan, Cambridge GB