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Duffy, PA
James E. Duffy, Landenberg, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090258435 | BIOTIN-RECEPTOR REAGENTS FOR SENSITIVITY MODULATION IN ASSAYS - Methods are disclosed for designing an antibody reagent for use in an assay for the detection of an analyte to obtain an optimum assay sensitivity and/or dynamic range. The antibody reagent is a conjugate of a small molecule attached by a spacer group to an antibody for the analyte. The method comprises controlling, in the preparation of the conjugate, reaction parameters comprising the hydrophobicity or hydrophilicity of the spacer group, the length of the spacer group, the number of molecules of the small molecule attached to the antibody and the point of attachment of the small molecule to the antibody to obtain an optimum assay sensitivity and/or dynamic range. In some embodiments the method comprises preparing two or more conjugates by selecting a set of parameters for each conjugate wherein the set of parameters is different for each conjugate, conducting an assay for the analyte employing each conjugate and selecting for use in the assay the conjugate that provides the optimum assay sensitivity and/or dynamic range. | 10-15-2009 |
James F. Duffy, Lafayette Hill, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20110126493 | HEAT AND PRESSURE RESISTANT BOTTLE WITH INCREASED OXYGEN BARRIER AND METHOD OF PRODUCTION - This invention provides a bottle that allows for easy and efficient application of shrink sleeves. The ease of application is partly a result of the invention's wall thickness along its body-forming portion. The body-forming portion of the invention has thick walls and thus exhibits negligible expansion during a hot-filling process. This permits a shrink sleeve to be placed onto the body-forming portion of the resistant bottle prior to filling. If the resistant bottle is hot-filled, the sleeve shrinks as a result of radiant heat emanating outwardly from the high temperature product, without the aid of an external heat source, such as a heat tunnel. | 06-02-2011 |
Karen E. Duffy, Radnor, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20080299138 | Toll-Like Receptor 3 Modulators and Uses Thereof - Modulators of TLR3 activity and their use are disclosed. | 12-04-2008 |
Kevin Duffy, Philadelphia, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20080255182 | Certain chemical entities, compositions, and methods - Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of one or more mitotic kinesins are disclosed. | 10-16-2008 |
| 20090286841 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS - Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of one or more mitotic kinesins are disclosed. | 11-19-2009 |
| 20090306127 | Certain Chemical Entities, Compositions and Methods - Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of one or more mitotic kinesins are disclosed. | 12-10-2009 |
| 20090312365 | Certain Chemical Entities, Compositions, and Methods - Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of one or more mitotic kinesins are disclosed. | 12-17-2009 |
Kevin Duffy, Collegeville, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20080214455 | Novel Chemical Compounds - This invention relates to newly identified compounds for inhibiting hYAK3 proteins and methods for treating diseases associated with hYAK3 activity. | 09-04-2008 |
| 20090203692 | NOVEL CHEMICAL COMPOUNDS - This invention relates to newly identified compounds for inhibiting hYAK3 proteins and methods for treating diseases associated with hYAK3 activity. | 08-13-2009 |
Kevin J Duffy, Collegevile, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20080261974 | Novel Chemical Compounds - This invention relates to newly identified compounds for inhibiting hYAK3 proteins and methods for treating diseases associated with the imbalance or inappropriate activity of hYAK3 proteins. | 10-23-2008 |
Kevin J. Duffy, Philadelphia, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20100069453 | Certain Chemical Entities, Compositions, and Methods - Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of one or more mitotic kinesins are disclosed. | 03-18-2010 |
Kevin M. Duffy, Alburtis, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20120128560 | Process and System for Syngas Treatment - A process for the clean-up of a crude syngas stream having widely varying composition and particulate load. The process includes quenching the crude syngas stream with a liquid stream to cool the syngas stream and remove particulates, tars and heavier hydrocarbon compounds. The process further includes co-scrubbing the syngas stream to remove both HCl and NH | 05-24-2012 |
Sean G. Duffy, Langhorne, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090198036 | Continuous Process for the Production of Moisture-Cure, Polyurethane Sealants and Adhesives - A process for continuous manufacturing of moisture-curable polyurethane formulations used as sealants and adhesives. The process is characterized by the fact that the reactive components are introduced independently, and without the need for a prepolymer, to a mixer. Solid or liquid raw materials can be either pre-blended or fed directly to the mixer, a twin-screw extruder, which provides the requisite energy to homogenously mix the raw materials and drive the chemical reaction. The process is designed so that the extruder barrel and screw allow variable feed addition and heat exchange down the length of the machine. This allows various operations to be performed at different points in the extruder, including reaction, dispersive mixing, distributive mixing and devolitization. | 08-06-2009 |
Shawn P. Duffy, Cheswick, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090054603 | LOW-CURE POWDER COATINGS AND METHODS FOR USING THE SAME - Low-cure powder coating compositions are disclosed. The compositions comprise a polyepoxide and a material having the structure | 02-26-2009 |
| 20090104372 | METHODS AND SYSTEMS FOR COATING SUBSTRATES - Disclosed are methods for coating a substrate. These methods include: (a) vertically orienting the substrate between a vertically oriented backstop and a spray gun; (b) at least partially coating the vertically oriented substrate with a substantially 100% solids, radiation curable liquid coating composition by passing the composition through the spray gun wherein the composition is atomized; whereby a portion of the atomized coating composition deposits on the vertically oriented substrate and a portion of the atomized coating composition deposits on the vertically oriented backstop; (c) exposing the coated substrate to ionizing radiation and/or actinic radiation to cure the coating composition deposited thereon; and (d) removing and reusing at least a portion of the coating composition deposited on the vertically oriented backstop. Related coating systems are also disclosed. | 04-23-2009 |
| 20110294942 | PIGMENT DISPERSIONS, RELATED COATING COMPOSITIONS AND COATED SUBSTRATES - Disclosed are pigment dispersions and coating compositions that include such pigment dispersions. The pigment dispersions include: (a) a pigment; (b) an acid functional, hydroxyl functional and secondary amine functional acrylic polymer having a weight average molecular weight of at least 11,000; and (c) a liquid carrier comprising an organic solvent. | 12-01-2011 |
Timothy J. Duffy, West Middlesex, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090247117 | CELLULAR TELEPHONE SYSTEM THAT USES POSITION OF A MOBILE UNIT TO MAKE CALL MANAGEMENT DECISIONS - A cellular telephone system has call management decisions made based on the exact geographic location of the mobile unit. These call management decisions include billing and taxing decisions, cell site selection, frequency selection and even cellular system selection. The decisions are continuously updated during a call whereby decisions can be made and changed regardless of where a call originated. Cell site location, and even cellular system selection, can be made in a specific manner to best serve the needs of the mobile user, the cellular system as well as the public. It is even possible for a cellular system to locate one or more of its cell sites in the geographic area served by another cellular system. In some cases, cellular systems might even share cell sites. | 10-01-2009 |