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Du, US

Bingchen Du, Rockville, MD US

Patent application numberDescriptionPublished
20110256469Platinum Adlayered Ruthenium Nanoparticles, Method for Preparing, and Uses Thereof - A superior, industrially scalable one-pot ethylene glycol-based wet chemistry method to prepare platinum-adlayered ruthenium nanoparticles has been developed that offers an exquisite control of the platinum packing density of the adlayers and effectively prevents sintering of the nanoparticles during the deposition process. The wet chemistry based method for the controlled deposition of submonolayer platinum is advantageous in terms of processing and maximizing the use of platinum and can, in principle, be scaled up straightforwardly to an industrial level. The reactivity of the Pt(31)-Ru sample was about 150% higher than that of the industrial benchmark PtRu (1:1) alloy sample but with 3.5 times less platinum loading. Using the Pt(31)-Ru nanoparticles would lower the electrode material cost compared to using the industrial benchmark alloy nanoparticles for direct methanol fuel cell applications.10-20-2011

Bingfan Du, Cambridge, MA US

Patent application numberDescriptionPublished
20090069297Aurora kinase modulators and method of use - The present invention relates to chemical compounds having a general formula I03-12-2009
20090163501Aurora kinase modulators and method of use - The present invention relates to chemical compounds having a general formula I06-25-2009
20110263530Aurora Kinase Modulators and Method of Use - The present invention relates to chemical compounds having a general formula I10-27-2011
20120122847AURORA KINASE MODULATORS AND METHOD OF USE - The present invention relates to chemical compounds having a general formula I05-17-2012

Patent applications by Bingfan Du, Cambridge, MA US

Daniel Y. Du, Milan, MI US

Patent application numberDescriptionPublished
20090192202ANDROGEN MODULATORS - The present invention is directed to a new class of 4-cyano-phenoxy-alkyl carboxyl derivatives and to their use as androgen receptor modulators. Other aspects of the invention are directed to the use of these compounds to decrease excess sebum secretions and to stimulate hair growth.07-30-2009
20100048517ANDROGEN MODULATORS - The present invention is directed to a new class of 4-cycloalkoxy benzonitriles and to their use as androgen receptor modulators. Other aspects of the invention are directed to the use of these compounds to decrease excess sebum secretions and to stimulate hair growth.02-25-2010

Patent applications by Daniel Y. Du, Milan, MI US

Daniel Yunlong Du, Milan, MI US

Patent application numberDescriptionPublished
20090105349ANDROGEN MODULATORS - The present invention is directed to the discovery of a new class of androgen receptor modulators. Other aspects of the invention are directed to the use of these compounds to decrease sebum secretion and to stimulate hair growth.04-23-2009

Eliza Yingzi Du, Indianapolis, IN US

Patent application numberDescriptionPublished
20110150334SYSTEM AND METHOD FOR NON-COOPERATIVE IRIS IMAGE ACQUISITION - A method segments iris images from eye image data captured from non-cooperative subjects. The method includes receiving a frame of eye image data, and determining whether a pupil exists in the image by detecting glare areas in the image. Upon finding a pupil, subsequent images are processed with reference to the pupil location and a radius is calculated for the pupil. A k means clustering method and principal component analysis are used to locate pupil boundary points, which are fitted to a conic. Using the pupil boundary, an angular derivative is computed for each frame having a pupil and iris boundary points are fitted to a conic to identify an iris region between the iris boundary and the pupil boundary. Noise data are then removed from the iris region to generate an iris segment. A method for evaluating iris frame quality and iris image segmentation quality is also disclosed.06-23-2011
20110182483SYSTEM AND METHOD FOR CANCELABLE IRIS RECOGNITION - A method of generating a biometric feature descriptor has been developed that includes acquiring an image of an anatomical feature having a biometric feature, isolating a region of the image having the biometric feature, extracting image data from the image of the region to identify a plurality of features for the biometric feature, transforming the extracted image data for each identified feature into a plurality of feature descriptors, mapping the feature descriptors for the plurality of features into a first arrangement of feature descriptors, generating a second arrangement of feature descriptors with a non-invertible transform of the first arrangement of feature descriptors, and storing the second arrangement of feature descriptors into an electronic database.07-28-2011

Fengxing Du, Chesterfield, MO US

Patent application numberDescriptionPublished
20110054246WHOLE GENOME SCAN TO DISCOVER QUANTITATIVE TRAI LOCI (QTL) AFFECTING GROWTH, BODY COMPOSITION, AND REPRODUCTION IN MATERNAL PIG LINES - The present invention provides compositions and methods useful for determining an animal's genotype and to select animals having a desired genotype. Embodiments of the invention also provide isolated nucleic acid molecules and analytical kits that may be used to determine an animal's genotype. Furthermore, the present invention provides methods for improving desirable animal traits including improved growth, enhanced body composition, and improved reproductive traits. The invention also provides methods for allocating animals for predetermined uses, for picking potential parent animals for breeding, and for producing progeny animals. The instant invention also provides methods for identifying associations between single nucleotide polymorphisms (SNPs) and phenotypic traits. Also provided are methods for identifying genetic markers in allelic association with the SNP disclosed herein and for identifying the genotypes of a causative mutation underlying a quantitative trait locus (QTL).03-03-2011

Fengxing Du, St. Louis, MI US

Patent application numberDescriptionPublished
20100304353METHODS OF IMPROVING A GENOMIC MARKER INDEX OF DAIRY ANIMALS AND PRODUCTS - The present invention provides methods for improving desirable dairy traits through the use of a genomic marker index. Also provided are methods for determining an animal's genotype with respect to multiple markers used in calculation of the genomic marker index. The invention also provides methods for selecting or allocating animals for predetermined uses, for picking potential parent animals for breeding, and for producing improved dairy products.12-02-2010
20110123983Methods of Using Genetic Markers and Related Epistatic Interactions - The present invention provides methods for improving desirable animal traits including improved fitness and productivity in dairy animals. Also provided are methods for determining a dairy animal's genotype with respect to multiple markers associated with fitness and/or productivity. The invention also provides methods for selecting or allocating animals for predetermined uses such as progeny testing or nucleus herd breeding, for picking potential parent animals for breeding, and for producing improved progeny animals. Each of the above methods may be further improved through the incorporation of interaction effects between multiple SNPs.05-26-2011

Fuliang Du, Mansfield, CT US

Patent application numberDescriptionPublished
20100227403rbLIF PROTEIN FOR USE IN EMBRYONIC STEM CELL CULTURES - Provided herein methods of maintaining an embryonic stem cell culture in an undifferentiated state, wherein the method includes culturing an embryonic stem cell on a rabbit feeder cell layer, wherein the rabbit feeder layer expresses a leukemia inhibitory factor (LIF) protein. Also provided are methods of maintaining an embryonic stem cell culture in an undifferentiated state, wherein the method includes culturing an embryonic stem cell in a culture medium comprising rabbit leukemia inhibitory factor (rbLIF) protein. Also provided are polynucleotide and amino acid sequences of a rabbit leukemia inhibitory factor protein (rbLIF).09-09-2010

George Du, Fairfield, NJ US

Patent application numberDescriptionPublished
20110112620Single continuous piece prosthetic tubular aortic conduit and method for manufacturing the same - A prosthetic aortic conduit for replacing a root portion of an aorta is provided. The conduit comprises a continuous tubular conduit along a substantially common axis. A portion of the tubular conduit does not substantially deform in a longitudinal direction and has resilient means which allow said another portion of the conduit to be expandable in a lateral direction. The portion that is able to deform laterally mimics the function of the sinuses of Valsalva. The method of manufacturing such a conduit comprises the steps of having a continuous weave of rows of yarn or the equivalent with a change in tightness of the rows so that in some portion of the conduit it is expandable in the lateral direction and in some portion of the conduit it is expandable in the longitudinal direction.05-12-2011

Haikun Du, Lake Worth, FL US

Patent application numberDescriptionPublished
20100241731METHOD FOR VIRTUALIZING INTERNET RESOURCES AS A VIRTUAL COMPUTER - A system and method for presenting a representation of a remotely located storage resource includes: using a processor device for: receiving a first request from a user, said first request including an identification of the storage resource; authenticating the user request; virtualizing the storage resource by creating a node for presentation to the user, wherein said node represents the storage resource; presenting the node to the user; receiving a second request from the user for data stored in the storage resource represented by the node; retrieving the requested data from the storage resource; and presenting the requested data to the user on the node.09-23-2010

Hao Du, Ann Arbor, MI US

Patent application numberDescriptionPublished
20090188903Method for welding process consistency - A method is provided for monitoring and controlling the process consistency of an arc welding process. The weld voltage signal is monitored and analyzed to determine the occurrence of the detachment of a weld droplet. The weld droplet detachment is determined via statistical techniques as having occurred at a normal interval following a prior detachment indicating consistent weld process or as a sporadic detachment having occurred at an irregular interval with respect to the prior detachment and indicating inconsistent weld process. The weld process is adjusted by controlling the weld process variables to maximize the predominance of droplet detachment at normal intervals and minimize the occurrence of the sporadic detachments.07-30-2009

Heng Du, Fort Lee, NJ US

Patent application numberDescriptionPublished
20100291074CYCLOPHILIN D-AMYLOID BETA INTERACTION POTENTIATES MITOCHONDRIAL DYSFUNCTION IN A TRANSGENIC MOUSE MODEL OF ALZHEIMER'S DISEASE - The present invention is directed to methods for treating or preventing Alzheimer's disease by administering therapeutically effective amounts of an agent that reduces Cyclophilin D expression in a patient, or that reduce Cyclophilin D activity or its ability to form a complex with Amyloid beta. Such agents include antisense nucleotides and small interfering RNAs, antibodies that selectively bind to Cyclophilin D, and cyclosporine A and D.11-18-2010

Hong Du, North Andover, MA US

Patent application numberDescriptionPublished
20090048333Zearalenone Macrolide Derivatives and Uses of the Same - The present invention provides compounds, pharmaceutical compositions and methods for the treatment of specific cancers. Such compositions may generally comprise a compound of formula (I):02-19-2009
20090082313Multikinase Inhibitors for Use in the Treatment of Cancer - The present invention provides compounds, pharmaceutical compositions and methods for the treatment of specific cancers. Such compositions may generally comprise a compound of formula (I):03-26-2009
20110144101MACROCYCLIC COMPOUNDS USEFUL AS PHARMACEUTICALS - The present invention provides methods for the use of compounds having formula (I) in the treatment of various disorders including inflammatory or autoimmune disorders, and disorders involving malignancy or increased angiogenesis, wherein R06-16-2011
20110237805INTERMEDIATES AND METHODS FOR MAKING ZEARALENONE MACROLIDE ANALOGS - Disclosed herein are methods and intermediates useful in the preparation of macrolides, e.g., compounds of formula (IV) wherein R09-29-2011

Patent applications by Hong Du, North Andover, MA US

Hong Du, Cincinnati, OH US

Patent application numberDescriptionPublished
20100239558Lipid Hydrolysis Therapy for Atherosclerosis and Related Diseases - The present invention comprises a method to diminish and/or eliminate atherosclerotic plaques, in mammals, through direct and indirect treatment of these plaques, in situ, using suitable substances which are capable of lipid removal, primarily through hydrolysis, either by a catalytic or stoichiometric process, wherein the substance targets receptors in and/or on the cell which lead to uptake into the lysosome. Such substances used to diminish and/or eliminate atherosclerotic plaques are generally comprised of lipid hydrolyzing proteins and/or polypeptides.09-23-2010

Hung T. Du, Reisterstown, MD US

Patent application numberDescriptionPublished
20090021090Power Tools With Motor Having a Multi-Piece Stator - A power tool has a motor having a stator made by separately forming pole pieces, return path pieces and field coils. The field coils are placed over necks of the pole path pieces and the return path pieces are affixed to the pole pieces. An armature having an outside diameter of at least 0.625 the outside diameter of the stator is placed in the stator. The field coils may be formed so that they extend beyond pole tips of the pole pieces.01-22-2009
20090200891Electric Motor Having A Field Assembly With Slot Insulation - An electric motor has a field assembly, such as a stator, for a dynamoelectric machine has field coils that are wound to a net shape. Lead wires are brought out from the ends of each field coil. The field coils are insulated with insulating sleeves or insulating slot liners. The field coils are assembled with stator core pieces, such as pole pieces and return path pieces, into the stator. The stator core pieces are formed prior to being assembled with the field coils. In an aspect of the invention, the pole pieces and return path pieces are separately formed and then assembled together with the field coils, which have also been separately formed.08-13-2009
20090206783Soft start for electric motor of a power tool - A power tool has an electric motor with field windings. In an aspect of the invention, each field winding includes two coils wound with the same number of turns of the same gauge magnet wire. When the motor is first energized, the two coils of each field winding are connected in series, reducing in-rush current. Upon expiration of a soft start period, which can be after the motor reaches a predetermined speed or upon expiration of a predetermined time period, the two coils of each field winding are connected in parallel. In another aspect of the invention, an electric motor used in a power tool includes field windings that are connected in series with a separate start winding when the motor is first energized. Upon expiration of the soft start period, the start winding is bypassed. In another aspect of the invention, the separate start winding includes two sub-windings. The two sub-windings are connected in a way that magnetic field created by the two sub-windings is counterbalanced so that the overall magnetic force created by the start winding in the motor armature is minimized or zero. Also, the voltage across the two sub-windings is minimized or zero. In another aspect, the field windings are connected in series with a start impedance when the motor is first energized and a time delay relay having a set of delay contacts coupled across the start impedance energized. Upon expiration of the soft start period, the time delay contacts close, bypassing the start impedance. In an aspect, the motor is a universal motor.08-20-2009
20100033036Motor With Permanent Magnets and Method of Manufacturing; Power Tool With Same - An electric motor has a rotor and a stator. The rotor or the stator has arced permanent magnets that have essentially the same inner radius (IR) and outer radius (OR). In an aspect, the stator has a stator housing having a plurality of poles. Each pole includes a plurality of flat magnets affixed to an inner surface of the stator housing. In an aspect, flats on the outside of the stator housing key the stator assembly in a power tool housing. In an aspect, flat magnets are pre-magnetized, pre-assembled with alternating magnetic polarities, inserted into a stator housing, and remagnetized to a final, desired magnetic polarity configuration. In an aspect, pre-magnetized magnets and unmagnetized magnets are pre-assembled with unmagnetized magnets between magnetized magnets, the pre-assembled magnets inserted into a stator housing, and the unmagnetized magnets magnetized to a final, desired magnetic polarity configuration. In an aspect, pre-magnetized magnets are inserted between anchors inwardly extending from an inner surface of a stator housing with the anchors retaining each magnet placed in the stator housing between anchors from being angularly displaced by subsequently inserted magnets. In an aspect, pre-magnetized magnets are inserted in recesses in an inner surface of a stator housing with the recesses retaining each magnet placed in the stator housing between anchors from being angularly displaced by subsequently inserted magnets. In an aspect, each pole has at least three magnets, at least one of the magnets being thinner than the other magnets. In an aspect, the outer most magnets are made of magnetic material that is more resistant to demagnetization than at least one of the other magnets. In an aspect, the magnets of each pole are unevenly spaced over the pole In an aspect, a power tool includes such an electric motor.02-11-2010
20110018370METHOD OF FORMING A POWER TOOL - An electric motor has a stator in which an armature is disposed. The armature has a lamination stack having slots in which magnet wires are wound. An armature shaft extends coaxially through the lamination stack and a commutator is disposed on the armature shaft to which ends of the magnet wires are electrically coupled. The magnet wires are at least partially encased in thermally conductive plastic. When the thermally conductive plastic is molded, a balancing feature is formed of the thermally conductive plastic. In aspects, the balancing feature can include a layer of the plastic from which plastic can be removed during balancing; one or more balancing rings adjacent axial sides of the lamination stack from which plastic can be removed to balance the armature; or one or more balancing rings having one or more pockets therein in which one or more weights are disposed to balance the armature.01-27-2011
20110115314POWER TOOLS WITH MOTOR HAVING A MULTI-PIECE STATOR - A power tool has a motor having a stator made by separately forming pole pieces, return path pieces and field coils. The field coils are placed over necks of the pole path pieces and the return path pieces are affixed to the pole pieces. An armature having an outside diameter of at least 0.625 the outside diameter of the stator is placed in the stator. The field coils may be formed so that they extend beyond pole tips of the pole pieces.05-19-2011
20110278966Motor With Overmolded Permanent Magnets - A permanent magnet electric motor has a stator and a rotor. The stator has a stator housing with at least a North pole and a South pole. Each pole includes at least two permanent magnets arranged on an inner surface of the stator housing near the pole tips and an overmold of magnetic material molded around the permanent magnets and over the inner surface of the stator between the permanent magnets. Alternatively, an overmold of magnetic material may be provided over an inner surface of the stator, where the thickness of the overmold layer is greater near tips of each pole than in the middle portion of each pole.11-17-2011
20110298313Motor With Permanent Magnets and Method of Manufacturing Power Tool With Same - A permanent magnet electric motor has a stator and a rotor. The stator has a stator housing with at least a North pole and a South pole, each pole including permanent magnets affixed to an inner surface of the stator housing, where at least two of the magnets within a pole have dissimilar characteristics, e.g., different widths or different grades of demagnetization resistance.12-08-2011

Patent applications by Hung T. Du, Reisterstown, MD US

Hung T. Du, Towson, MD US

Patent application numberDescriptionPublished
20090101379Cordless Power Tool Having Multi-Speed Transmission and Constant Speed in Light Torque Range - A cordless power tool (04-23-2009

Jeff Du, Redmond, WA US

Patent application numberDescriptionPublished
20080320525Audio stream management for television content - Audio stream management techniques are described. In an implementation, a unique representation is generated by a client for each of a plurality of audio streams associated with television content received at the client. Each of the unique representations is displayed in a user interface at the client to be selectable by a user to cause output of a respective audio stream with the television content12-25-2008

Jerry G. Du, Princeton, NJ US

Patent application numberDescriptionPublished
20120058259ELECTROLESS NICKEL ALLOY PLATING BATH AND PROCESS FOR DEPOSITING THEREOF - An aqueous nickel phosphorus tin alloy electroless plating bath and process for depositing a nickel phosphorus tin alloy onto a substrate, particularly an aluminum substrate for memory disk applications, wherein the nickel phosphorus tin alloy deposit provides enhanced thermal stability, as defined by the inhibition of crystallization and suppression of magnetization upon high temperature annealing when compared to typical NiP deposits.03-08-2012

Jian Hua Du, Orlando, FL US

Patent application numberDescriptionPublished
20100006273THERMALLY CONDUCTIVE POROUS ELEMENT-BASED RECUPERATORS - A heat exchanger includes at least one hot fluid flow channel comprising a first plurality of open cell porous elements having first gaps therebetween for flowing a hot fluid in a flow direction and at least one cold fluid flow channel comprising a second plurality of open cell porous elements having second gaps therebetween for flowing a cold fluid in a countercurrent flow direction relative to the flow direction. The thermal conductivity of the porous elements is at least 10 W/m·K. A separation member is interposed between the hot and cold flow channels for isolating flow paths associated these flow channels. The first and second plurality of porous elements at least partially overlap one another to form a plurality of heat transfer pairs which transfer heat from respective ones of the first porous elements to respective ones of the second porous elements through the separation member.01-14-2010

John Du, Beaverton, OR US

Patent application numberDescriptionPublished
20090307108BUSINESS PROCESS AND APPARATUS FOR ONLINE PURCHASES USING A RULE-BASED TRANSFERABLE SHOPPING BASKET - An online shopping basket is acquired by a buyer from an online store and is customized according to rules specified by the buyer. The buyer places zero or more items in the online shopping basket(s) before they are given to at least one shopper by the online store. The shopper(s) may further customize the online shopping basket(s) with rules that do not conflict with those specified by the buyer. The shopper(s) then place zero or more items in the online shopping basket(s) and return the basket(s) to the online store. Multiple online shopping baskets are merged into a single basket, and the buyer reviews the items in the merged online shopping basket and adds or removes items as necessary. The buyer then purchases the remaining items from the online store.12-10-2009
20100318643SYSTEMS AND METHODS FOR VIRTUALIZING FUNCTIONS AND DECENTRALIZING SERVICE DELIVERY IN A FLAT NETWORK OF INTERCONNECTED PERSONAL DEVICES - Systems and methods are described herein to virtualize functions and decentralize services in a flat-graph network of client devices. Other embodiments include apparatus and systems of devices comprising virtual node modules to perform a variety of service functions. Further embodiments include methods for overlaying service functions on a flat-graph network of client devices.12-16-2010

Patent applications by John Du, Beaverton, OR US

Kien S. Du, Durham, NC US

Patent application numberDescriptionPublished
20100029650BICYCLIC COMPOUNDS AND USE AS ANTIDIABETICS - The present invention relates to novel compounds that are useful in the treatment of metabolic disorders, particularly type II diabetes mellitus and related disorders, and also to the methods for the making and use of such compounds.02-04-2010
20100105654SUBSTITUTED QUINAZOLINONE COMPOUNDS - A variety of small molecule, guanidine-containing molecules capable of acting as MC4-R agonists are provided. The compounds are useful in treating MC4-R mediated diseases when administered to subjects. The compounds have the structures VA, VB, VIIA and VIIB where the values of the variables are defined herein.04-29-2010
20120077812BICYCLIC COMPOUNDS AND USE AS ANTIDIABETICS - The present invention relates to novel compounds that are useful in the treatment of metabolic disorders, particularly type II diabetes mellitus and related disorders, and also to the methods for the making and use of such compounds.03-29-2012

Patent applications by Kien S. Du, Durham, NC US

Li Du, Broomfield, CO US

Patent application numberDescriptionPublished
20090044084Combined DC restoration double detection and loops - A method of double detection in a perpendicular magnetic read channel is disclosed. The method generally includes the steps of (A) generating an intermediate signal by performing a first detection on an input signal of the perpendicular read channel, the first detection having a first error rate, (B) generating a statistics signal based on the intermediate signal, the statistics signal conveying noise statistics that depend on data in the input signal and (C) generating an output signal by performing a second detection on the input signal using the noise statistics to reduce a second error rate of the second detection compared with the first error rate, wherein the first detection is independent of the second detection.02-12-2009
20100157464Systems and Methods for Adaptive MRA Compensation - Various embodiments of the present invention provide systems and methods for reducing head distortion. For example, various embodiments of the present invention provide storage devices that include a storage medium, a read/write head assembly, and an adaptive distortion modification circuit. The storage medium includes information that may be sensed by the read/write head assembly that is disposed in relation to the storage medium. The adaptive distortion modification circuit receives the information sensed by the read/write head assembly and adaptively estimates and implements a distortion compensation factor in the analog domain. In some instances of the aforementioned embodiments, the read/write head assembly includes a magneto resistive head. In such instances, the distortion compensation factor is designed to compensate for non-linear distortion introduced by the magneto resistive head.06-24-2010

Li Du, Akron, OH US

Patent application numberDescriptionPublished
20100109686METAL WEAR DETECTION APPARATUS AND METHOD EMPLOYING MICROFLUIDIC ELECTRONIC DEVICE - An apparatus and a method for detection of wear particles in a lubricant are disclosed. The apparatus includes a microfluidic device including a microchannel sized for a lubricant containing wear particles to pass therethrough and first and second electrodes extending into the microchannel. A detection system is coupled with the electrodes for detection of wear particles passing through the microchannel, based on a change in capacitance of the electrodes.05-06-2010

Libin Du, Jersey City, NJ US

Patent application numberDescriptionPublished
20120136109Composite Polymer Emulsion - A polymerization process to copolymerize hydrophobic ethylenically unsaturated C05-31-2012

Libin Du, Chapel Hill, NC US

Patent application numberDescriptionPublished
20100216928POLYMER PARTICLE COMPOSITE HAVING HIGH FIDELITY ORDER, SIZE, AND SHAPE PARTICLES - A polymer composite includes a polymer and an additive encased in the polymer, wherein the additive includes a plurality of isolated particles where each particle of the plurality of particles has a substantially predetermined three dimensional shape and is substantially oriented with respect to each other in a predetermined two dimensional array.08-26-2010

Libin Du, Cleveland, OH US

Patent application numberDescriptionPublished
20100016531PROCESS OF FLUOROMONOMER POLYMERIZATION - Methods of making fluoropolymers from at least one fluoromonomerin either (1) a heterogeneous medium comprising a carbon dioxide and an aqueous phase with or without hydrocarbon surfactants or dispersants or stabilizer, or (2) a homogenous medium containing carbon dioxide with one or more organic solvents, are described.01-21-2010

Libin Du, Forest Hills, OH US

Patent application numberDescriptionPublished
20110245399Dispersion Of Hybrid Polyurethane With Olefin-Acrylic Copolymerization - A product and processes comprising urethane polymer and at least one copolymer from a hydrophobic ethylenically unsaturated C10-06-2011

Ling Du, Akron, OH US

Patent application numberDescriptionPublished
20100216037CARBON-FILLED POLYMER COMPOSITE BIPOLAR PLATES FOR PROTON EXCHANGE MEMBRANE FUEL CELLS - Proton exchange membrane (PEM) fuel cells, also known as polymer electrolyte membrane fuel cells, consist of a proton conducting membrane or a proton exchange membrane possessing adequate proton conducting properties typically contained between two platinum impregnated porous electrodes. PEM fuel cells are used in the transportation, stationary and portable applications and are currently used in the automobile industry as the fuel cell favored for replacement of the internal combustion engine. An opportunity exists for the development of lightweight and highly conductive polymer-based bipolar plates produced by standard mass production techniques, such as extrusion or compression and injection molding. The present invention capitalizes this opportunity and discloses method and compositions of matter for manufacturing of lightweight, low cost carbon-filled polymer composite bipolar plates.08-26-2010

Liqun Du, Pullman, WA US

Patent application numberDescriptionPublished
20100223690COMPOSITIONS AND METHODS FOR MODULATING PLANT DISEASE RESISTANCE AND IMMUNITY - Provided are methods for enhancing plant cell disease resistance, comprising (1) generating a homozygous gene modification of AtSR1 (or AtSR1 ortholog or homolog) in a plant or plant cell characterized by sialic acid-mediated systemic acquired resistance (SA-mediated SAR), wherein said gene modification reduces or eliminates the calmodulin-binding activity of the respective AtSR1 or AtSR1 ortholog or homolog; or (2) expression of a recombinant or mutant AtSR1 sequence (or AtSR1 gene ortholog or homolog sequence) encoding a modified AtSR1, or AtSR1 ortholog or homolog protein, in a plant or plant cell, wherein said protein modification reduces or eliminates the calmodulin-binding activity of the respective AtSR1 or AtSR1 ortholog or homolog protein. Plants and/or plant cells comprising said modified AtSR1, or AtSR1 ortholog or homolog proteins, and/or said expression means (e.g., recombinant expression vector or expressible recombinant and/or mutant sequences), along with nucleic acids encoding said modified proteins are provided.09-02-2010

Mingliang Du, Copley, OH US

Patent application numberDescriptionPublished
20100065183TURNUP REINFORCING STRUCTURE FOR PNEUMATIC TIRES - A pneumatic tire includes a tread, two inextensible annular beads, a carcass ply having two turnup end portions, and an annular cap structure encompassing one of the turnup end portions. Each turnup end portion is wrapped around one of the annular beads. The cap structure has a U-shaped cross-section for surrounding the turnup end portion. The cap structure is constructed of reinforced fabric with fibers oriented in the range from −45° to +45° with respect to a radial direction of the pneumatic tire.03-18-2010
20100065184REINFORCING STRUCTURE FOR PNEUMATIC TIRES - A pneumatic tire includes a tread, two annular bead portions, a carcass ply having two turnup end portions, a first reinforcing structure disposed at one of the bead portions, and an annular first cap structure encompassing a first end portion of the first reinforcing structure. Each turnup end portion is wrapped around one of the annular bead portions. The first reinforcing structure is disposed at one of the bead portions. The first cap structure encompasses the first end portion of the first reinforcing structure. The first cap structure has a U-shaped cross-section for surrounding the first end portion. The first cap structure is constructed of reinforced fabric with fibers oriented in the range from −45° to +45° with respect to a radial direction of the pneumatic tire.03-18-2010

Pengwei Du, Richland, WA US

Patent application numberDescriptionPublished
20110270452SCHEDULING AND MODELING THE OPERATION OF CONTROLLABLE AND NON-CONTROLLABLE ELECTRONIC DEVICES - Disclosed herein are representative embodiments of methods, apparatus, and systems for controlling and scheduling power distribution in a power network, such as household power network. One disclosed embodiment is a system comprising a central controller and a control device coupled to a household appliance. The central controller can comprise computing hardware coupled to a wireless transceiver. The central controller can be configured to generate and transmit control signals for controlling the operational state of the household appliance according to the schedule. Furthermore, the control device can be configured to receive the transmitted control signals from the central controller and to control the operational state of the household appliance in response to the control signals.11-03-2011

Phong Du, Newark, DE US

Patent application numberDescriptionPublished
20100313340PROTECTIVE CHITOSAN LAMINATES - Provided are laminates containing in order: a fabric layer with an oil and water repellant coating, a continuous chitosan film, a continuous water vapor permeable polyurethane layer, and a fabric layer. The laminates, which have improved function in high moisture environments, can be used to make a variety of finished articles that can be used to provide protection from hazardous chemical and biological agents.12-16-2010
20120108127POLYAMIDE COMPOSITE STRUCTURES AND PROCESSES FOR THEIR PREPARATION - Disclosed herein are composite structures, overmolded composites structures and processes for their preparation. The disclosed composite structures have a surface having at least a portion made of a surface resin composition, and comprise a fibrous material being impregnated with a matrix resin composition, wherein the matrix polyamide resin composition and the surface resin composition are selected from polyamide compositions comprising a blend of semi-aromatic polyamides.05-03-2012
20120108130OVERMOLDED POLYAMIDE COMPOSITE STRUCTURES AND PROCESS FOR THEIR PREPARATION - Disclosed herein are overmolded composite structures and processes for their preparation. The disclosed overmolded composite structures comprise i) a first component having a surface, of which at least a portion made of a surface resin composition, and comprising a fibrous material being impregnated with a matrix resin composition, ii) a second component comprising an overmolding resin composition, wherein said second component is adhered to said first component over at least a portion of the surface of said first component, and wherein the matrix resin composition and the surface resin composition are identical or different polyamide compositions.05-03-2012

Robert Du, Canton, MI US

Patent application numberDescriptionPublished
20110012413RECLINING SEAT ASSEMBLY - An eccentric free pivot for a reclining seat assembly may include a seat cushion, a seatback, a gear system, an input mechanism, a rod, and an eccentric pivot. The gear system may pivotally couple the seat cushion to the seatback. A rod extending generally across the seat assembly may be coupled to the gear system on one side and the eccentric pivot on the other side. When the gear system and/or input mechanism rotate the rod and eccentric pivot, this rotation causes the side of the seatback opposite the gear system and/or input mechanism to move up and down.01-20-2011

Ruyu Du, Carmel, IN US

Patent application numberDescriptionPublished
20100160433TREATMENT OF NEURODEGENERATIVE AND CARDIOVASCULAR DISORDERS - A method of treating a neurodegenerative or cardiovascular disorder with a compound of the following formula:06-24-2010

Shawn Du, Macedonia, OH US

Patent application numberDescriptionPublished
20090021936LINEAR LED ILLUMINATION SYSTEM - A linear LED light module and system includes a heat sink, a printed circuit board, a plurality of LEDs, a power supply housing, a flexible electrical conductor, a first electrical connector, a second electrical connector, and a power supply. The heat sink is elongated in an axial direction along a longitudinal axis that is parallel with a greatest dimension of the heat sink. The PCB is in thermal communication with the heat sink and includes circuitry. The plurality of LEDs mount to the PCB and are in electrical communication with the circuitry of the PCB. The power supply housing connects to the heat sink. The flexible electrical conductor includes at least two wires that are configured to accommodate an AC line voltage of at least 120 VAC. The first electrical connector is at a first end of the electrical conductor. The second electrical connector is at a second end of the electrical conductor. The second connector has a configuration that complements the first connector so that the second connector can connect to an associated adjacent first connector of an associated adjacent LED module to allow a plurality of similar LED modules to be mechanically and electrically connected to one another. The power supply is disposed in the power supply housing and in electrical communication with the circuitry of the PCB and the electrical conductor. The power supply is configured to receive the AC line voltage from the electrical conductor and to convert the received AC line voltage to a lower DC voltage for delivery to the circuitry of the PCB to drive the LEDs mounted on the PCB.01-22-2009

Shoucheng Du, Pittsburgh, PA US

Patent application numberDescriptionPublished
20080261950Compounds that inhibit cholinesterase - Compounds that inhibit cholinesterase activity and, upon hydrolysis release a pharmacologically active agent. The compounds of the invention are employed in methods to treat an individual. The pharmacologically active agent obtained by hydrolysis of the compound can treat, for example, a nervous system condition, a cholinergic deficiency and conditions or diseases associated with a deficiency in a pharmacologically active agent, such as acetylcholine.10-23-2008
20110144177Carbamoyl Esters That Inhibit Cholinesterase And Release Pharmacologically Active Agents - Carbamoyl esters inhibit cholinesterase activity and, upon hydrolysis release a pharmacologically active agent. In one embodiment, the carbamoyl ester has the following structure:06-16-2011

Patent applications by Shoucheng Du, Pittsburgh, PA US

Shu Du, Erie, PA US

Patent application numberDescriptionPublished
20100274269Single probe with disturber - A single probe percutaneous surgical instrument for de-bulking/removing thrombus/clog/calculi has an actuator assembly (10-28-2010

Patent applications by Shu Du, Erie, PA US

Shu-Yuan Du US

Patent application numberDescriptionPublished
20090044291DROUGHT-RESISTANT PLANTS AND METHOD FOR PRODUCING THE PLANTS - This application provides a recombinant expression cassette for expressing the H subunit of Mg-chelatase, a plant gene product that is newly identified as an abscisic acid receptor. Also provided are a transgenic plant with drought-resistance and a method for producing such plants.02-12-2009

Tao Tom Du, North Potomac, MD US

Patent application numberDescriptionPublished
20110195031METHODS FOR THE USE OF PROGESTOGEN AS A GLUCOCORTICOID SENSITIZER - Provided are methods and kits for administering progestogen as a glucocorticoid sensitizer to restore corticosteroid sensitivity or reverse the glucocorticoid insensitivity or enhance glucocorticoid sensitivity, in order to treat one or more glucocorticoid insensitivity related diseases or conditions. For example, these include methods for reversing the glucocorticoid insensitivity in a subject having no history of menstrual cycle-related exacerbation or allergy to self-hormones, particularly progesterone, such as premenstrual or perimenstrual deterioration in the symptoms, e.g., premenstrual worsening of atopic dermatitis or premenstrual exacerbations of asthma, and exhibiting relatively or totally refractory responses to glucocorticoid therapy, e.g., glucocorticoid resistance. The methods and kits provide for the administration of a sex hormone to the subject who is corticosteroid dependent or corticoid resistant or unresponsive or intolerant to corticosteroids.08-11-2011
20110262502PULMONARY DELIVERY OF 17-HYDROXYPROGESTERONE CAPROATE (17-HPC) - The invention relates to 17-HPC pulmonary formulations for administration by inhalation comprising 17-HPC and a pharmaceutically acceptable excipient. Particle size reduction of 17-HPC is required for the pulmonary delivery, and can be achieved with a surfactant or water without the surfactant. Preferred pulmonary formulations include a powder blend comprising a therapeutically effective amount of at least one steroid hormone (progestogen) as a glucocorticoid sensitizer, and at least one pharmaceutically acceptable excipient, wherein the at least one steroid hormone (progestogen) has a particle size distribution profile ranging from about one nanometer to about ten microns in the powder blend.10-27-2011

Tianbao Du, Beaverton, OR US

Patent application numberDescriptionPublished
20100038584Polishing Composition and Polishing Method Using the Same - A polishing composition for electrochemical mechanical polishing a surface of an object in which the polishing composition contains a phosphate electrolyte such as a potassium phosphate, a chelating agent such as a potassium citrate, a corrosion inhibitor such as benzotriazole, an oxidizing agent such as hydrogen peroxide, and a solvent such as water. The polishing composition preferably further contains abrasive particles such as colloidal silica particles.02-18-2010

Tianbo Du, Beaverton, OR US

Patent application numberDescriptionPublished
20080277787METHOD AND PAD DESIGN FOR THE REMOVAL OF BARRIER MATERIAL BY ELECTROCHEMICAL MECHANICAL PROCESSING - A method and apparatus for processing barrier and metals disposed on a substrate in an electrochemical mechanical planarizing system are provided. In certain embodiments a method for electroprocessing a substrate is provided. The method comprises contacting the substrate with the non-conductive surface of a polishing pad assembly, establishing a first electrically conductive path through an electrolyte between an exposed layer of barrier material and a first electrode, establishing a second electrically conductive path through the electrolyte between the exposed layer of barrier material and a second electrode, applying a voltage to the first electrode to cause a voltage drop between the substrate and the second electrode, and removing the barrier material from the substrate.11-13-2008

Wenhui Du, Toledo, OH US

Patent application numberDescriptionPublished
20110111550HYBRID WINDOW LAYER FOR PHOTOVOLTAIC CELLS - A novel photovoltaic solar cell and method of making the same are disclosed. The solar cell includes: at least one absorber layer which could either be a lightly doped layer or an undoped layer, and at least a doped window-layers which comprise at least two sub-window-layers. The first sub-window-layer, which is next to the absorber-layer, is deposited to form desirable junction with the absorber-layer. The second sub-window-layer, which is next to the first sub-window-layer, but not in direct contact with the absorber-layer, is deposited in order to have transmission higher than the first-sub-window-layer.05-12-2011

Wenjun Du, St. Louis, MO US

Patent application numberDescriptionPublished
20090234105Construction of a Multivalent SCFV Through Alkyne-Azide 1,3-Dipolar Cycloaddition - The present invention provides for a practical, universal and efficient method to ligate two large macromolecules (e.g., proteins) using the alkyne-azide 1,3-dipolar cycloaddition reaction to produce a conjugated macromolecule, such as a multivalent scFv. The present invention also provides for conjugate macromolecules comprising a plurality of macromolecule components cross-linked through at least one linking group comprising at least one 1,2,3-triazole moiety, wherein at least 50 percent of the macromolecule components in the conjugate macromolecule has only one site available for cross-linking.09-17-2009

Wenjun Du, Mount Pleasant, MI US

Patent application numberDescriptionPublished
20110251378ONE-POT SYNTHESIS OF ALPHA/BETA-O-GLYCOLIPIDS - The present invention provides a one-pot method of preparing an unprotected α-O-glycolipid. The first step involves contacting a protected α-iodo sugar with a catalyst and a lipid comprising a hydroxy group, under conditions sufficient to prepare a protected α-O-glycolipid. The second step involves deprotecting the protected α-O-glycolipid under conditions sufficient to prepare the unprotected α-O-glycolipid, wherein the contacting and deprotecting steps are performed in a single vessel. The present invention also provides a one-pot method of preparing an unprotected β-O-glycolipid following the steps for the preparation of the unprotected α-O-glycolipid.10-13-2011

Wu Du, Monroe Township, NJ US

Patent application numberDescriptionPublished
20100184758BETA CARBOLINE DERIVATIVES AS ANTIDIABETIC COMPOUNDS - Beta-carboline derivatives of structural formula I are selective antagonists of the somatostatin subtype receptor 3 (SSTR3) and are useful for the treatment of Type 2 diabetes mellitus and of conditions that are often associated with this disease, including hyperglycemia, insulin resistance, obesity, lipid disorders, and hypertension. The compounds are also useful for the treatment of depression and anxiety.07-22-2010
20100184799OXADIAZOLE BETA CARBOLINE DERIVATIVES AS ANTIDIABETIC COMPOUNDS - Beta-carboline derivatives of structural formula I are selective antagonists of the somatostatin subtype receptor 3 (SSTR3) and are useful for the treatment of Type 2 diabetes mellitus and of conditions that are often associated with this disease, including hyperglycemia, insulin resistance, obesity, lipid disorders, and hypertension. The compounds are also useful for the treatment of depression and anxiety.07-22-2010

Xian Xian Du, Pittsburgh, KS US

Patent application numberDescriptionPublished
20110060115High bio-content hybrid natural oil polyols and methods therefor - Methods of producing a hybrid petro-plant oil polyol having a high bio-content by coupling a petro-chemical polyol with a plant oil based polyol is provided, including coupling an intermediate petro-polyol prepolymer with a plant oil polyol so as to synthesize a hybrid petro-plant oil polyol having a high bio-content and a hydroxyl number of between about 50 and 60.03-10-2011

Xian Xian Du, Pittsburg, KS US

Patent application numberDescriptionPublished
20090292099Polyols from plant oils and methods of conversion - Methods of producing plant polyols from plant oils include reacting a plant oil with a designed reactant having one or more nucleophilic functional groups and one or more active hydrogen functional groups in the presence of an addition reaction catalyst in a single reaction step. The resultant polyols may be directly reacted with polyisocyanates to produce polyurethanes.11-26-2009
20110166315Coupling method for providing high molecular weight natural oil polyol - Methods of coupling plant oil based polyols so as to synthesis high molecular weight plant oil polyols having a hydroxyl number between from about 40 to about 60. The resultant polyols may be directly reacted with polyisocyanates to produce polyurethanes.07-07-2011
20120116042Method of synthesizing tuneably high functionality in high molecular weight natural oil polyols - Methods of one-pot synthesis of high molecular weight natural oil polyols having a functionality of between about 4 and about 8 are provided. The resultant polyols may be directly reacted with polyisocyanates to produce polyurethanes.05-10-2012
20120116043Method for providing higher molecular weight natural oil polyols without loss of functionality - Methods of one-pot synthesis of high molecular weight natural oil polyols having a functionality of at least two are provided. The resultant polyols may be directly reacted with polyisocyanates to produce polyurethanes.05-10-2012

Patent applications by Xian Xian Du, Pittsburg, KS US

Xiaogang Du, Wilsonville, OR US

Patent application numberDescriptionPublished
20090172486TESTING EMBEDDED MEMORIES IN AN INTEGRATED CIRCUIT - Various new and non-obvious apparatus and methods for testing embedded memories in an integrated circuit are disclosed. One of the disclosed embodiments is an apparatus for testing an embedded memory in an integrated circuit. This exemplary embodiment comprises input logic that includes one or more memory-input paths coupled to respective memory inputs of the embedded memory, a memory built-in self-test (MBIST) controller, and at least one scan cell coupled between the input logic and the MBIST controller. The scan cell of this embodiment is selectively operable in a memory-test mode and a system mode. In memory-test mode, the scan cell can apply memory-test data to the memory inputs along the memory-input paths of the integrated circuit. Any of the disclosed apparatus can be designed, simulated, and/or verified (and any of the disclosed methods can be performed) in a computer-executed application, such as an electronic-design-automation (“EDA”) software tool.07-02-2009
20110145774TESTING EMBEDDED MEMORIES IN AN INTEGRATED CIRCUIT - Various new and non-obvious apparatus and methods for testing embedded memories in an integrated circuit are disclosed. One of the disclosed embodiments is an apparatus for testing an embedded memory in an integrated circuit. This exemplary embodiment comprises input logic that includes one or more memory-input paths coupled to respective memory inputs of the embedded memory, a memory built-in self-test (MBIST) controller, and at least one scan cell coupled between the input logic and the MBIST controller. The scan cell of this embodiment is selectively operable in a memory-test mode and a system mode. In memory-test mode, the scan cell can apply memory-test data to the memory inputs along the memory-input paths of the integrated circuit. Any of the disclosed apparatus can be designed, simulated, and/or verified (and any of the disclosed methods can be performed) in a computer-executed application, such as an electronic-design-automation (“EDA”) software tool.06-16-2011

Patent applications by Xiaogang Du, Wilsonville, OR US

Xiao Hong Du, Colorado Springs, CO US

Patent application numberDescriptionPublished
200901033482T/2C FERROELECTIC RANDOM ACCESS MEMORY WITH COMPLEMENTARY BIT-LINE LOADS - The signal margin of a small array 2T/2C memory is increased by writing the ferroelectric load capacitors on the bit lines to complementary states. A ferroelectric memory array includes rows and columns of 2T/2C memory cells, wherein each column of the memory array includes a first memory subcell having a first node coupled to a word line, a second node coupled to a first bit line, and a third node coupled to a first plate line, the first memory cell being poled in a first direction; a second memory subcell having a first node coupled to the word line, a second node coupled to a second bit line, and a third node coupled to the first plate line, the second memory cell being poled in a second direction; a first load subcell having a first node coupled to the word line, a second node coupled to the first bit line, and a third node coupled to a second plate line, the first load cell being poled in the first direction; and a second load subcell having a first node coupled to the word line, a second node coupled to a second bit line, and a third node coupled to the second plate line, the second load cell being poled in the second direction.04-23-2009
20090108887FAST POWER-ON DETECT CIRCUIT WITH ACCURATE TRIP-POINTS - A power-on reset circuit includes a first PNP transistor having an emitter, a base, and a collector coupled to ground; a second PNP transistor having an emitter coupled to the base of the first transistor, and a base and collector coupled to ground; a third PNP transistor having an emitter, a base coupled to the base of the first transistor, and a collector coupled to ground; a first resistor coupled between VDD and an internal node; a second resistor coupled between VDD and the emitter of the first transistor; a third resistor coupled between the internal node and the emitter of the third transistor; and a comparator having a first input coupled to the internal node and a second input coupled to the emitter of the first transistor for generating a power-on reset signal.04-30-2009

Patent applications by Xiao Hong Du, Colorado Springs, CO US

Xiaohua Du, Somerset, NJ US

Patent application numberDescriptionPublished
20100072170SHORT PITCH METAL GRATINGS AND METHODS FOR MAKING THE SAME - Methods for forming a metal grating include providing a first grating including a plurality of grating lines formed from a dielectric material, each grating having a pair of sidewalls, facing sidewalls of adjacent grating lines being separated by corresponding trenches, the grating lines and trenches forming a grating surface; forming a layer of a metal on the grating surface, where the metal layer has a constant thickness and conforms to the grating surface; and removing portions of the metal layer between sidewalls of adjacent grating lines of the first grating to form a metal grating having grating lines formed from the metal, the grating lines of the metal grating corresponding to the portions of the metal layer adjacent the sidewalls of the grating lines of the first grating. The metal grating has a pitch of 200 nm or less, a depth of 50 nm or more, and the grating lines of the metal grating have an aspect ratio of 10-to-1 or more.03-25-2010

Xiaosong Du, Morganville, NJ US

Patent application numberDescriptionPublished
20090150369METHOD AND APPARATUS TO PROVIDE MULTIMEDIA SERVICE USING TIME-BASED MARKUP LANGUAGE - A multimedia player and method is disclosed for displaying multimedia content on a video screen. A video stream and a markup language segment associated with the video stream are received, wherein the markup language segment comprising a time stamp identifying a target segment of the video stream, and at least one keyword associated with the time stamp. The keyword is transmitted over a network to a search engine, and related content is received from the search engine over the network, wherein the related content is related to the keyword. When the target segment of the video stream is displayed on the video screen, the related content is concurrently displayed on the video screen.06-11-2009

Yan Du, Bridgewater, NJ US

Patent application numberDescriptionPublished
20100056514THIENOPYRAZOLES - Thienopyrazoles, their preparation, pharmaceutical compositions comprising these compounds, and their pharmaceutical uses in the treatment of disease states capable of being modulated by the inhibition of the protein kinases, in particular interleukin-2 inducible tyrosine kinase (ITK).03-04-2010

Yanan Du, Cambridge, MA US

Patent application numberDescriptionPublished
20110300570METHOD AND SYSTEM FOR GENERATING SPATIALLY AND TEMPORALLY CONTROLLABLE CONCENTRATION GRADIENTS - The ability to rapidly generate concentration gradients of diffusible molecules has important applications in many chemical and biological studies. The present invention is directed to methods and systems for generating spatially and temporally controllable concentration gradients of molecules (i.e. proteins or toxins) in a portable microfluidic device. The formation of the concentration gradients can be initiated by an induced forward flow and further optimized during an induced backward flow. The forward and backward flows can be either passively induced and/or actively pumped. The centimeter-length gradients along the microfluidic channel can be spatially and temporally controlled by the backward flow. The gradient profile was stabilized by stopping the flow. In one example, a stabilized concentration gradient of a cardiac toxin, Alpha-cypermethrin, generated according to the invention was used to test the response of HL-1 cardiac cells in the microfluidic device, which correlated with toxicity data obtained from multi-well plates. The invention can be useful for bio-logical and chemical processes that require rapid generation of concentration gradients in a portable microfluidic device.12-08-2011

Yangsheng Du, Westfield, IN US

Patent application numberDescriptionPublished
20120129931CAFFEIC ACID DERIVATIVES AND THEIR USE IN IMPROVING NEURONAL CELL VIABILITY - This invention relates to caffeic acid derivatives and improving viability of neuronal cells by contacting neuronal cells by caffeic acid derivatives as shown in the specification.05-24-2012

Yansheng Du, Westfield, IN US

Patent application numberDescriptionPublished
20080220085PRODUCTION OF NEURAL PROTECTIVE AND REGENERATIVE FACTORS FROM STEM CELLS AND TREATMENT OF NERVOUS SYSTEM CONDITIONS THEREWITH - A method for producing stem cell conditioned media for treatment of neurological insults is provided herein. By providing for the culture of adipose stem cells, and collecting the supernatants thereof, the supernatants have been shown to effect biological activity in preventing neural death when the supernatants are administered to a patient that has or is about to be subjected to a neural insult.09-11-2008
20100160433TREATMENT OF NEURODEGENERATIVE AND CARDIOVASCULAR DISORDERS - A method of treating a neurodegenerative or cardiovascular disorder with a compound of the following formula:06-24-2010
20110046410Method for Producing Caffeic Acid Phenyl Ester and Its Analogues - A method for producing caffeic acid phenyl ester and its analogues, which includes the steps of: (i) reacting, in a solvent, a salt of a compound of formula (II)02-24-2011
20120064029COMPOSITIONS FOR TREATING NERVOUS SYSTEM CONDITIONS - Compositions for treating nervous system conditions. In at least one embodiment of a stem cell conditioned medium of the present disclosure, the stem cell comprises a cell culture supernatant containing at least one factor capable of exerting effective neuroprotection to treat a mammalian neural injury or insult, the cell culture supernatant produced by culturing at least one mammalian adipose stem cell to produce the at least one factor.03-15-2012
20120064030METHODS OF TREATING NERVOUS SYSTEM CONDITIONS - Methods of treating nervous system conditions. In at least one embodiment of a method of treating a mammalian patient having a neuronal injury or insult of the present disclosure, the method comprises the step of administering a therapeutically-effective dose of a stem cell conditioned medium to a mammalian patient, the stem cell conditioned medium comprising a cell culture supernatant containing at least one factor capable of exerting effective neuroprotection to treat a mammalian neural injury or insult.03-15-2012

Patent applications by Yansheng Du, Westfield, IN US

Yansheng Du, Carmel, IN US

Patent application numberDescriptionPublished
20120100122COMBINATION THERAPY - A pharmaceutical composition containing a mitochondrial electron transport chain enhancer (or an antioxidant) and a compound of formula (I) shown in the specification. This pharmaceutical composition can be used to treat neurodegenerative disorders.04-26-2012

Ying Jun Du, North Billerica, MA US

Patent application numberDescriptionPublished
20100174245System for pretreating the lumen of a catheter - A method of and system for pretreating the lumen of a catheter or small diameter tubing. A vacuum chamber includes a microwave port and a microwave supply subsystem including a microwave generator, and a circular polarizer produces circularly polarized microwaves propagated into the vacuum chamber via the port at a frequency which produces electron cyclotron resonance. A magnetic coil about the vacuum chamber generates a magnetic field in the vacuum chamber with magnetic field lines co-linear with the propagation direction of the microwaves. A catheter manifold positions at least one catheter in the vacuum chamber and supplies a gas within the catheter lumen to generate a plasma in the lumen for pretreating the same.07-08-2010

Yingzi Du, Indianapolis, IN US

Patent application numberDescriptionPublished
20100202668System And Method For Measuring Clarity Of Images Used In An Iris Recognition System - An image quality measuring method enables a biometric image to be evaluated to determine whether the biometric image data are adequate for identification processing. The method includes converting a biometric image to dimensionless image data, filtering the dimensionless image data with a band pass filter, identifying a plurality of portions in the filtered data as containing identification features, each portion in the plurality having an information measurement that indicates feature content greater than portions in the filtered data that are excluded from the plurality, and measuring clarity for the biometric image from the identified plurality of portions in the filtered data.08-12-2010

Yiping Du, Aurora, CO US

Patent application numberDescriptionPublished
20090312625METHOD FOR FAST MULTI-SLICE MAPPING OF MYELIN WATER FRACTION - Mapping of myelin water content in white matter may provide important information for early diagnosis of multiple sclerosis and the detection of white matter abnormality in other diseases. It is disclosed here that free induction decay (FID) of each voxel at multiple slice locations is acquired in the brain using an echo-planar spectroscopic imaging (EPSI) pulse sequence. The multi-slice EPSI acquisition is designed to have a short first echo time (˜2 ms) and echo-spacing (˜1 ms) in order to acquire multiple sampling points during the fast decay of the myelin water signal. Multi-compartment analysis is then applied to the FID in each pixel using a 3-pool model of white matter to obtain quantitative maps of the myelin water fraction. Using this technique, the MR data for whole brain mapping of the myelin water can be acquired in less than 10 minutes, making this technique feasible for routine clinical applications.12-17-2009
20110275926Susceptibility Weighted Magnetic Resonance Imaging Of Venous Vasculature - Methods, systems, and devices are described for substantially simultaneous acquisition of magnetic resonance angiography (MRA) and magnetic resonance venography (MRV) data. Some embodiments provide susceptibility weighted magnetic resonance imaging of vasculature, including generating a multi-echo pulse sequence having a repetition time, and a first echo and a second echo during the repetition time; acquiring MRA data from at least the first echo; and acquiring MRV data from at least the second echo. The MRA data and/or the MRV data may also be post-processed (e.g., filtered, displayed, etc.). Various embodiments provide additional functionality, including techniques for processing data from an unsampled portion of one echo using sampled data from another echo.11-10-2011

Yu Du, Raleigh, NC US

Patent application numberDescriptionPublished
20090110806METHOD FOR PRODUCING AN ELECTRODE AND DEVICE - A method includes: coat a slurry that includes a carbon material, a water-insoluble binder, and a water-soluble polymer on a surface of a current collector to form a template structure; then dry the template structure; and finally, contact the template structure to an aqueous solution, and thereby to remove the water-soluble polymer and to form at least one electrode having a plurality of pores.04-30-2009
20090159460ELECTRODIALYSIS DEVICE AND PROCESS - A device includes a first electrode and a second electrode spaced from the first electrode to define a volume. An anion exchange membrane and a cation exchange membrane are disposed within the volume. A controller controls a supply of electrical current from an electrical source to the first electrode and to the second electrode. The electrical current supply is controlled to switch from a first mode of operation to a second mode of operation providing electrical current having a reverse polarity during each cycle. The electrical current is supplied at a controlled cycle rate and for a controlled duration. The cycle rate is greater than about 100 hertz and less than about 10 kilohertz.06-25-2009

Yu Du, Christiansburg, VA US

Patent application numberDescriptionPublished
20100218775SOUND-ATTENUATING EARMUFF HAVING ISOLATED DOUBLE-SHELL STRUCTURE - An earmuff assembly with a double-shell structure is disclosed for use with a sound-attenuating circumaural headset. The earmuff assembly comprises a cup-shaped outer shell mounted on a resilient outer sealing ring and a cup-shaped inner shell mounted on a resilient inner sealing ring. By means of the two sealing rings the outer and the inner shells are brought into abutment with the head surface around an ear of a wearer. Both shells are structurally rigid. The sound attenuation performance is maximized by isolating the inner shell from the outer shell.09-02-2010

Patent applications by Yu Du, Christiansburg, VA US

Yuhong Du, Atlanta, GA US

Patent application numberDescriptionPublished
20110281908Aminoquinoline Derived Heat Shock Protein 90 Inhibitors, Methods Of Preparing Same, And Methods For Their Use - Novel classes of molecular chaperone Heat shock protein 90 (Hsp90) inhibitors and methods for making these classes are provided herein. These compounds are useful in treating and preventing cancer and other Hsp90-related diseases, such as inflammation and neurodegenerative disorders. Also provided herein are methods of treating and preventing cancer and other Hsp90 related disease. The methods include administering to a subject a therapeutically effective amount of an Hsp90 inhibitor.11-17-2011
20120022070Heat Shock Protein 90 Inhibitors, Methods Of Preparing Same, And Methods For Their Use - Novel classes of molecular chaperone Heat shock protein 90 (Hsp90) inhibitors are disclosed. These compounds are useful in treating and preventing cancer and other Hsp90-related diseases and conditions, such as inflammation and neurodegenerative disorders. Methods of treating and preventing cancer and other Hsp90 related diseases and conditions are disclosed that include administering to the subject a therapeutically effective amount of an Hsp90 inhibitor. Methods of preparing the novel Hsp90 inhibitors are also provided.01-26-2012

Zaiwei Du, Bellevue, WA US

Patent application numberDescriptionPublished
20100125549MAINTAINING CLIENT DATA INTEGRITY IN A DISTRIBUTED ENVIRONMENT USING ASYNCHRONOUS DATA SUBMISSION - Data processing architecture where submitters can write data and/or metadata changes to a destination through an asynchronous interface. The architecture includes a ticketing system that issues a ticket (a unique identifier) to the submitter in response to receiving a changelist from the submitter. When the changes are successfully completed at the destination, the cached destination data can be re-downloaded to the submitter, and the changes cached in the submitter, discarded. Absent this capability, a user has to manually manage the cached changes and cached data. The architecture can be distributed in that multiple submitters can submit changelists. The destination provides data integrity by managing submissions to assist in ensuring data integrity across multiple submissions. Automatic changelist cleanup is provided on the submitter so that changelists do not impact performance, memory, and storage.05-20-2010

Zhong-Wei Du, Madison, WI US

Patent application numberDescriptionPublished
20090239305Gene recombination exchange system for stable gene modification in human ES cells - A method of creating a human pluripotent transgenic stem cell, wherein heterologous DNA is inserted into specific “hot-spots” in the genome where stable and high gene expression may occur, is disclosed. In one embodiment, the method comprises the steps of: (a) selecting a pluripotent stem cell line, and (b) inserting heterologous DNA at an insertion site selected from the group consisting of insertion site one and insertion site two to form a transgenic cell line. In another embodiment, the heterologous DNA is an exchange cassette and the transgenic cell line formed is a master cell line.09-24-2009
20100159595METHOD OF GENERATING MYELINATING OLIGODENDROCYTES - A method of differentiating embryonic stem cells into oligodendroglial precursor cells and oligodendroglial cells by culturing a population of cells comprising a majority of cells that are characterized by a neural tube-like rosette morphology and are Pax6+/Sox1+ into a population of cells that are PDGFRα+.06-24-2010

Zhunming Du, Cary, NC US

Patent application numberDescriptionPublished
20100033936Method and apparatus for rapid and dynamic RF and microwave circuit prototyping and integration - A method and apparatus for rapid and dynamic RF and Microwave circuit prototyping and integration provides a standard test fixture for testing any single device from any device vendors, provides a rapid dynamic tool for sub-system and system integration and prototyping, provides a flexibility to make any single function or multi-function assembled module quickly and economically. This prototyping approach can help RF/microwave companies share development times and costs. The combination of standard PCB function cells and dynamic standard mechanical cells helps build a prototype design quickly and reduce R&D costs.02-11-2010

Zijin Du, Chesterfield, MO US

Patent application numberDescriptionPublished
20090188005METHODS FOR GENETIC CONTROL OF PLANT PEST INFESTATION AND COMPOSITIONS THEREOF - The present invention is directed to controlling plant pest infestation, and particularly plant nematode infestation, by inhibiting one or more biological functions in the plant pest. The invention discloses methods and compositions for use in controlling plant pest infestation by providing one or more different recombinant double stranded RNA molecules in the diet of the pest in order to achieve a reduction in pest infestation through suppression of pest gene expression. The invention is also directed to methods for making transgenic plants that express the double stranded RNA molecules, to methods for detecting cells comprising the disclosed sequences, and to methods for detecting the disclosed sequences in biological samples.07-23-2009