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Drazen
Drazen Borkovic, Mountain View, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110055792 | Method and Apparatus for Circuit Partitioning and Trace Assignment in Circuit Design - Methods and apparatuses for incremental circuit partitioning and incremental trace assignment. In one embodiment of the present invention, a cost function based on both the partitioning solution and the trace assignment solution is used for the partitioning of a circuit; in reducing the cost function, blocks of circuits are moved among partitions and the trace assignment are updated accordingly to evaluate the cost function. In one embodiment, the traces and nets are grouped according to the partitions they connect for trace assignment. In one embodiment, a flow diagram is constructed for assigning nets to traces; and, maximum flow algorithms are used. In one embodiment, a flow diagram includes feedthrough solutions, in which flow conservation is not preserved at certain nodes. In one embodiment, integer linear programming techniques are used for assigning nets to traces. In one embodiment, a distribution of nets, which defines the numbers of blocks that each net has in each partition, is computed and maintained for efficient determination of the number of nets in net groups. | 03-03-2011 |
Drazen Cavuzic, Zagred HR
| Patent application number | Description | Published |
|---|---|---|
| 20090306393 | PROCESS FOR PREPARING OF, IMPURITIES FREE, SUBSTITUTED 2-BENZIMIDAZOLE-SULFOXIDE COMPOUND - The present invention relates to an improved process for the preparation of pantoprazole free from overoxidation impurities. The process enables better control of the process and therefore the quality of the products obtained, avoiding the formation of impurities. | 12-10-2009 |
Drazen Cavuzic, Zagreb HR
| Patent application number | Description | Published |
|---|---|---|
| 20090149427 | PHARMACEUTICALLY ACCEPTABLE SALTS AND HYDRATES OF RISEDRONIC ACID - The present invention is concerned with new hydrated forms of risedronate salts, processes of preparing the new hydrated forms, pharmaceutical compositions containing the same, therapeutic uses thereof and methods of treatment employing the same. In particular, the present invention provides tri-sodium risedronate dihydrate. | 06-11-2009 |
| 20110015413 | PROCESS FOR PREPARING CRYSTALLINE CALCIUM MUPIROCIN DIHYDRATE - Provided herein are methods of preparing crystalline mupirocin calcium dihydrate comprising combining solid mupirocin, solid calcium carbonate, and water in an amount sufficient to form a heterogeneous mixture and precipitate crystalline mupirocin calcium dihydrate from the mixture. In some embodiments, the methods produce nanocrystalline mupirocin calcium dihydrate, suitable for use in pharmaceutical formulations. | 01-20-2011 |
Drazen Kostelac, Roemerbeg DE
| Patent application number | Description | Published |
|---|---|---|
| 20100310648 | PHARMACEUTICAL DOSAGE FORM FOR ORAL ADMINISTRATION OF A BCL 2 FAMILY INHIBITOR - The invention relates to a pharmaceutical dosage form which comprises a solid dispersion product comprising N-(4-(4-((2-(4-chlorophenyl)-5,5-dimethyl-1-cyclohex-1-en-1-yl)methyl)piperazin-1-yl)benzoyl)-4-(((1R)-3-(morpholin-4-yl)-1-((phenylsulfanyl)methyl)propyl)amino)-3-((trifluoromethyl)sulfonyl)benzenesulfonamide or a salt, hydrate or solvate thereof, at least one pharmaceutically acceptable polymer, and at least one pharmaceutically acceptable solubilizer. The invention is further directed to processes for preparing the pharmaceutical dosage form and to use of the dosage form for treating proliferative disorders. | 12-09-2010 |
Drazen Kostelac, Roemerberg DE
| Patent application number | Description | Published |
|---|---|---|
| 20100297194 | FORMULATION FOR ORAL ADMINISTRATION OF APOPTOSIS PROMOTER - An orally deliverable pharmaceutical composition comprises as a sole or first active ingredient a compound of Formula I defined herein or a pharmaceutically acceptable salt thereof, for example ABT-263 free base or ABT-263 bis-HCl salt, dispersed, in a free base equivalent amount of at least about 2.5% by weight of the composition, in a pharmaceutically acceptable carrier; wherein said active ingredient is in solid-state form and/or the composition further comprises, dispersed in the carrier, a pharmaceutically acceptable heavier-chalcogen antioxidant in an amount effective to inhibit oxidation of the active ingredient at a thioether linkage thereof. The composition is suitable for oral administration to a subject in need thereof for treatment of a disease characterized by overexpression of one or more anti-apoptotic Bcl-2 family proteins, for example cancer. | 11-25-2010 |
Drazen Raucher, Madison, MS US
| Patent application number | Description | Published |
|---|---|---|
| 20100022466 | THERMALLY-TARGETED DELIVERY OF MEDICAMENTS INCLUDING DOXORUBICIN - Elastin-like polypeptide (ELP) serves as a vector for thermally-targeted delivery of therapeutics, including cytotoxic chemotherapeutic drugs such as doxorubicin. Examples of an ELP-based delivery vehicle can comprise: (1) a cell penetrating peptide, such as a Tat protein, (2) ELP, and (3) the lysosomally degradable glycylphenylalanylleucylglycine (GFLG) spacer and a cysteine residue conjugated to therapeutic such as doxorubicin, or a analog thereof. | 01-28-2010 |
Drazen Rot, Frankfurt Am Main DE
| Patent application number | Description | Published |
|---|---|---|
| 20120111087 | Compensation of measuring errors in handling equipment - A method is provided for compensating measuring errors for handling equipment with a drive carrier that includes a carrier part and driven drums for moving the steel cables arranged thereon and including a handling receptacle in which the handling receptacle is suitable for picking up loads and is connected to the carrier part by deflection pulleys via the support cables and a controllable lever mechanism that is at least connected to at least two support cables and with at least two force sensors that capture the forces of at least two support cables and a monitoring device that monitors the forces of the at least two force sensors. An adjustment angle of the controllable lever mechanism is captured by sensors and a correction of the cable forces based on the captured adjustment angle is carried in the monitoring device. | 05-10-2012 |
Drazen Sajatovic, Asperg DE
| Patent application number | Description | Published |
|---|---|---|
| 20120043309 | GLOW PLUG AND METHOD FOR CONNECTING A PIN MADE OF FUNCTIONAL CERAMIC TO A METAL SLEEVE - The invention relates to a glow plug comprising a housing in which an inner conductor is disposed, a metal sleeve which is inserted into the housing, and a ceramic glow pin which is disposed in the metal sleeve, wherein the two ends of the glow pin protrude from the metal sleeve and the rear end of the pin is connected to the inner conductor, and wherein the metal sleeve has a tapering section at the rear end, the section enclosing a tapering section of the glow pin. According to the invention, the glow pin is pressed into the metal sleeve. The invention further relates to a method for connecting a pin made of functional ceramic to a metal sleeve. | 02-23-2012 |
Drazen Veselovac, Aachen DE
| Patent application number | Description | Published |
|---|---|---|
| 20100132528 | TOOL CONDITION MONITORING SYSTEM - The invention relates to a tool comprising a tool element which rotates in operation with at least one geometrically defined blade, in particular a material cutting tool element, said tool element being subject to an operating parameter in the operating condition. A measuring device is provided for determination and conversion of the operation parameter into a measured signal. A first measuring device cooperates with a first tool element in the operating condition such that essentially only a first operating parameter for the first tool element may be recorded by the first measuring device | 06-03-2010 |