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Draney
Dan Draney, Lincoln, NE US
| Patent application number | Description | Published |
|---|---|---|
| 20080206764 | Flowcell system for single molecule detection - The present invention provides compounds, methods and systems for sequencing nucleic acid using single molecule detection. Using labeled NPs that exhibit charge-switching behavior, single-molecule DNA sequencing in a microchannel sorting system is realized. In operation, sequencing products are detected enabling real-time sequencing as successive detectable moieties flow through a detection channel. By electrically sorting charged molecules, the cleaved product molecules are detected in isolation without interference from unincorporated NPs and without illuminating the polymerase-DNA complex. | 08-28-2008 |
| 20110039266 | FLOWCELL SYSTEMS FOR SINGLE MOLECULE DETECTION - The present invention provides compounds, methods and systems for sequencing nucleic acid using single molecule detection. Using labeled NPs that exhibit charge-switching behavior, single-molecule DNA sequencing in a microchannel sorting system is realized. In operation, sequencing products are detected enabling real-time sequencing as successive detectable moieties flow through a detection channel. By electrically sorting charged molecules, the cleaved product molecules are detected in isolation without interference from unincorporated NPs and without illuminating the polymerase-DNA complex. | 02-17-2011 |
Daniel R. Draney, Lincoln, NE US
| Patent application number | Description | Published |
|---|---|---|
| 20100080758 | OPTICAL FLUORESCENT IMAGING - Compounds and methods are disclosed that are useful for noninvasive imaging in the near-infrared (NIR) spectral range. The NIR is highly sensitive for tumor detection and tracking. The application discloses targeting a tumor-enriched cell surface receptor with a ligand-conjugated fluorescent probe, which specifically allows detection of the tumor relative to the negligible animal autofluorescence. | 04-01-2010 |
| 20100323389 | FLUORESCENT IMAGING WITH SUBSTITUTED CYANINE DYES - Compounds and methods are disclosed that are useful for noninvasive imaging in the near-infrared spectral range. The cyanine compounds of Formula I are presented: | 12-23-2010 |
Ryan Draney, Goddard, KS US
| Patent application number | Description | Published |
|---|---|---|
| 20100064473 | Attachment Bolt And Tensioned Support System Using Same - Attachment bolts and tensioned support systems (e.g., aircraft access systems) are set forth herein. According to one embodiment, an attachment bolt for use in a tensioned support system includes a head portion and a shaft portion extending from the head portion. The head portion has an end face, and the shaft portion has at least one thread and a tip distal to the head portion. A cavity extends entirely through the head and shaft portions and has a linearly extruded segment, an extended diameter at the end face, and an enlarged diameter at the tip. The extended diameter is larger than a diameter of the linearly extruded segment, and the enlarged diameter is larger than the diameter of the linearly extruded segment. | 03-18-2010 |